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Article ; Online: Nut bush pesticide limits: urgent need for a comprehensive strategy to address current and emerging insect pests and insecticide options in the Australian macadamia industry.

Ellis, Kirsten L / Anderson, Jay M / Yonow, Tania / Kriticos, Darren J / Andrew, Nigel R

2024

Abstract: In Australia, macadamia orchards are attacked by four main insect pest groups. Management and control of three of these key pests currently relies on broad-spectrum insecticides whose long-term future is questionable. Of the 23 insecticides registered ... ...

Abstract	In Australia, macadamia orchards are attacked by four main insect pest groups. Management and control of three of these key pests currently relies on broad-spectrum insecticides whose long-term future is questionable. Of the 23 insecticides registered for use in macadamia in Australia, 19 face issues affecting their availability and 12 are presently not approved in the EU, the USA or Canada. These international markets may refuse produce that does not adhere to their own insecticide use standards, hence Australian produce may be excluded from market access. Many of the potential replacement integrated pest management methods of pest control are generally considered less effective by the industry and have not been adopted. There are 17 insect pest groups identified by the industry, any of which have potential to become major problems if broad-spectrum insecticide options become unavailable. Thirteen pest groups need urgent attention as they are at risk of losing current effective control methods, and no replacement solutions have yet been developed. The lag period for research and development to identify new chemical and biological control solutions means there is now an urgent need for the macadamia industry to craft a strategy for sustainable pest management for each pest. Critically, this industry strategy needs to address the vulnerabilities identified in this paper, identify potential solutions for any cases of market failure and consider funding mechanisms to address these gaps. On economic and sustainability grounds, potential biological control options should be explored, especially in cases where insecticide control options are vulnerable. © 2024 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Language	English
Publishing date	2024-02-26
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2001705-4
ISSN	1526-4998 ; 1526-498X
ISSN (online)	1526-4998
ISSN	1526-498X
DOI	10.1002/ps.8043
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Article ; Online: Trends in Oral Tongue Cancer Incidence in the US.

Burus, Todd / Damgacioglu, Haluk / Huang, Bin / Christian, W Jay / Hull, Pamela C / Ellis, Amanda R / Arnold, Susanne M / Deshmukh, Ashish A / Lang Kuhs, Krystle A

JAMA otolaryngology-- head & neck surgery

2024

Abstract: Importance: Oral tongue cancer (OTC) incidence has increased rapidly among young (<50 years) non-Hispanic White individuals in the US during the past 2 decades; however, it is unknown if age-associated trajectories have persisted.: Objective: To ... ...

Abstract	Importance: Oral tongue cancer (OTC) incidence has increased rapidly among young (<50 years) non-Hispanic White individuals in the US during the past 2 decades; however, it is unknown if age-associated trajectories have persisted. Objective: To examine US trends in OTC incidence and project future case burden. Design, setting, and participants: This cross-sectional analysis of OTC incidence trends used the US Cancer Statistics Public Use Database, which covers approximately 98% of the US population, and included individuals with an OTC diagnosis reported to US cancer registries between January 1, 2001, and December 31, 2019. Exposures: Sex, race and ethnicity, and age. Main outcomes and measures: Estimated average annual percentage change in OTC incidence from 2001 to 2019. Given the substantial incidence rate increases among non-Hispanic White individuals compared with those of racial and ethnic minority groups, subsequent analyses were restricted to non-Hispanic White individuals. Forecasted OTC incidence trends and case burden among non-Hispanic White individuals to 2034. Results: There were 58 661 new cases of OTC identified between 2001 and 2019. Male individuals (57.6%), non-Hispanic White individuals (83.7%), those aged 60 years or older (58.0%), and individuals with localized stage disease at diagnosis (62.7%) comprised most cases. OTC incidence increased across all age, sex, and racial and ethnic groups, with marked increases observed among non-Hispanic White individuals (2.9% per year; 95% CI, 2.2%-3.7%). Increases among female individuals aged 50 to 59 years were most notable and significantly outpaced increases among younger non-Hispanic White female individuals (4.8% per year [95% CI, 4.1%-5.4%] vs 3.3% per year [95% CI, 2.7%-3.8%]). While all non-Hispanic White birth cohorts from 1925 to 1980 saw sustained increases, rates stabilized among female individuals born after 1980. Should trends continue, the burden of new OTC cases among non-Hispanic White individuals in the US is projected to shift more toward older individuals (from 33.1% to 49.3% among individuals aged 70 years or older) and female individuals (86% case increase vs 62% among male individuals). Conclusions and relevance: The results of this cross-sectional study suggest that the period of rapidly increasing OTC incidence among younger non-Hispanic White female individuals in the US is tempering and giving way to greater increases among older female individuals, suggesting a birth cohort effect may have been associated with previously observed trends. Recent increases among non-Hispanic White individuals 50 years or older of both sexes have matched or outpaced younger age groups. Continuing increases among older individuals, particularly female individuals, may be associated with a shift in the OTC patient profile over time.
Language	English
Publishing date	2024-04-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2701825-8
ISSN	2168-619X ; 2168-6181
ISSN (online)	2168-619X
ISSN	2168-6181
DOI	10.1001/jamaoto.2024.0301
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Article ; Online: Pain management strategies in penile implantation.

Ellis, Jeffrey L / Higgins, Andrew M / Simhan, Jay

Asian journal of andrology

2019 Volume 22, Issue 1, Page(s) 34–38

Abstract: The opioid epidemic continues to be a serious public health concern. Many have pointed to prescription drug misuse as a nidus for patients to become addicted to opioids and as such, urologists and other surgical subspecialists must critically define ... ...

Abstract	The opioid epidemic continues to be a serious public health concern. Many have pointed to prescription drug misuse as a nidus for patients to become addicted to opioids and as such, urologists and other surgical subspecialists must critically define optimal pain management for the various procedures performed within their respective disciplines. Controlling pain following penile prosthesis implantation remains a unique challenge for urologists, given the increased pain patients commonly experience in the postoperative setting. Although most of the existing urological literature focuses on interventions performed in the operating room, there are many studies that examine the role of preoperative adjunctive pain medicine in diminishing postoperative narcotic requirements. There are relatively few studies looking at postoperative strategies for managing pain in prosthetic surgery with follow-up past the immediate hospitalization. This review assess the various strategies employed for managing pain following penile implantation through the lens of the current state of the opioid crisis, thus examining how urologists can responsibly treat pain without contributing to the growing threat of opioid addiction.
MeSH term(s)	Analgesics/therapeutic use ; Analgesics, Opioid/therapeutic use ; Anesthetics, Local/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Cyclooxygenase 2 Inhibitors/therapeutic use ; Gabapentin/therapeutic use ; Humans ; Intraoperative Care ; Male ; Nerve Block/methods ; Opioid Epidemic ; Pain Management/methods ; Pain, Postoperative/prevention & control ; Pain, Postoperative/therapy ; Penile Implantation/methods ; Pregabalin/therapeutic use ; Preoperative Care
Chemical Substances	Analgesics ; Analgesics, Opioid ; Anesthetics, Local ; Anti-Inflammatory Agents, Non-Steroidal ; Cyclooxygenase 2 Inhibitors ; Pregabalin (55JG375S6M) ; Gabapentin (6CW7F3G59X)
Language	English
Publishing date	2019-08-29
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2075824-8
ISSN	1745-7262 ; 1008-682X
ISSN (online)	1745-7262
ISSN	1008-682X
DOI	10.4103/aja.aja_91_19
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Article ; Online: Community Assessments for Public Health Emergency Response (CASPERs)-US Virgin Islands, 2017-2018.

Schnall, Amy Helene / Wolkin, Amy Funk / Roth, Joseph Jay / Ellis, Esther M

American journal of public health

2019 Volume 109, Issue S4, Page(s) S303–S308

Abstract: Objectives. ...

Abstract	Objectives.
MeSH term(s)	Cyclonic Storms ; Disaster Planning/methods ; Drinking Water ; Emergencies ; Food Supply/statistics & numerical data ; Humans ; Needs Assessment ; Public Health ; United States Virgin Islands
Chemical Substances	Drinking Water
Language	English
Publishing date	2019-10-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	121100-6
ISSN	1541-0048 ; 0090-0036 ; 0002-9572
ISSN (online)	1541-0048
ISSN	0090-0036 ; 0002-9572
DOI	10.2105/AJPH.2019.305161
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Article ; Online: Quantitative artifact reduction and pharmacologic paralysis improve detection of EEG epileptiform activity in critically ill patients.

Kulick-Soper, Catherine V / Shinohara, Russell T / Ellis, Colin A / Ganguly, Taneeta M / Raghupathi, Ramya / Pathmanathan, Jay S / Conrad, Erin C

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

2022 Volume 145, Page(s) 89–97

Abstract: Objective: Epileptiform activity is common in critically ill patients, but movement-related artifacts-including electromyography (EMG) and myoclonus-can obscure EEG, limiting detection of epileptiform activity. We sought to determine the ability of ... ...

Abstract	Objective: Epileptiform activity is common in critically ill patients, but movement-related artifacts-including electromyography (EMG) and myoclonus-can obscure EEG, limiting detection of epileptiform activity. We sought to determine the ability of pharmacologic paralysis and quantitative artifact reduction (AR) to improve epileptiform discharge detection. Methods: Retrospective analysis of patients who underwent continuous EEG monitoring with pharmacologic paralysis. Four reviewers read each patient's EEG pre- and post- both paralysis and AR, and indicated the presence of epileptiform discharges. We compared the interrater reliability (IRR) of identifying discharges at baseline, post-AR, and post-paralysis, and compared the performance of AR and paralysis according to artifact type. Results: IRR of identifying epileptiform discharges at baseline was slight (N = 30; κ = 0.10) with a trend toward increase post-AR (κ = 0.26, p = 0.053) and a significant increase post-paralysis (κ = 0.51, p = 0.001). AR was as effective as paralysis at improving IRR of identifying discharges in those with high EMG artifact (N = 15; post-AR κ = 0.63, p = 0.009; post-paralysis κ = 0.62, p = 0.006) but not with primarily myoclonus artifact (N = 15). Conclusions: Paralysis improves detection of epileptiform activity in critically ill patients when movement-related artifact obscures EEG features. AR improves detection as much as paralysis when EMG artifact is high, but is ineffective when the primary source of artifact is myoclonus. Significance: In the appropriate setting, both AR and paralysis facilitate identification of epileptiform activity in critically ill patients.
MeSH term(s)	Humans ; Electroencephalography ; Artifacts ; Critical Illness ; Retrospective Studies ; Myoclonus/diagnosis ; Reproducibility of Results ; Paralysis/diagnosis
Language	English
Publishing date	2022-11-18
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1463630-x
ISSN	1872-8952 ; 0921-884X ; 1388-2457
ISSN (online)	1872-8952
ISSN	0921-884X ; 1388-2457
DOI	10.1016/j.clinph.2022.11.007
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Article ; Online: Cones and cone pathways remain functional in advanced retinal degeneration.

Ellis, Erika M / Paniagua, Antonio E / Scalabrino, Miranda L / Thapa, Mishek / Rathinavelu, Jay / Jiao, Yuekan / Williams, David S / Field, Greg D / Fain, Gordon L / Sampath, Alapakkam P

Current biology : CB

2023 Volume 33, Issue 8, Page(s) 1513–1522.e4

Abstract: Most defects causing retinal degeneration in retinitis pigmentosa (RP) are rod-specific mutations, but the subsequent degeneration of cones, which produces loss of daylight vision and high-acuity perception, is the most debilitating feature of the ... ...

Abstract	Most defects causing retinal degeneration in retinitis pigmentosa (RP) are rod-specific mutations, but the subsequent degeneration of cones, which produces loss of daylight vision and high-acuity perception, is the most debilitating feature of the disease. To understand better why cones degenerate and how cone vision might be restored, we have made the first single-cell recordings of light responses from degenerating cones and retinal interneurons after most rods have died and cones have lost their outer-segment disk membranes and synaptic pedicles. We show that degenerating cones have functional cyclic-nucleotide-gated channels and can continue to give light responses, apparently produced by opsin localized either to small areas of organized membrane near the ciliary axoneme or distributed throughout the inner segment. Light responses of second-order horizontal and bipolar cells are less sensitive but otherwise resemble those of normal retina. Furthermore, retinal output as reflected in responses of ganglion cells is less sensitive but maintains spatiotemporal receptive fields at cone-mediated light levels. Together, these findings show that cones and their retinal pathways can remain functional even as degeneration is progressing, an encouraging result for future research aimed at enhancing the light sensitivity of residual cones to restore vision in patients with genetically inherited retinal degeneration.
MeSH term(s)	Humans ; Retinal Degeneration/metabolism ; Retinal Cone Photoreceptor Cells/physiology ; Retina/metabolism ; Retinitis Pigmentosa/genetics ; Retinitis Pigmentosa/metabolism ; Color Vision
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/j.cub.2023.03.007
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Article: Recent and Projected Trends in Oral Tongue Cancer in the United States: A Demographic Shift in Case Burden as Early Onset Increases Among Females Subside.

Burus, Todd / Damgacioglu, Haluk / Huang, Bin / Christian, W Jay / Hull, Pamela C / Ellis, Amanda R / Arnold, Susanne M / Deshmukh, Ashish A / Kuhs, Krystle A Lang

Research square

2023

Abstract: Background: Oral tongue cancer (OTC) incidence has increased rapidly among young (< 50 years) non-Hispanic White (NHW) individuals in the United States (U.S.) over the last two decades; however, it is unknown if age-associated trajectories have ... ...

Abstract	Background: Oral tongue cancer (OTC) incidence has increased rapidly among young (< 50 years) non-Hispanic White (NHW) individuals in the United States (U.S.) over the last two decades; however, it is unknown if age-associated trajectories have persisted. Furthermore, incidence trends for all 50 U.S. states and the District of Columbia have never been investigated. Materials and methods: Using U.S. Cancer Statistics data, we investigated incidence trends from 2001-2019, overall and according to age, sex, race/ethnicity, and state of residence. We used age-period-cohort analysis to explore temporal patterns among birth cohorts and to project future trends and case counts. Results: OTC incidence increased across all age, sex, and racial/ethnic groups, with marked increases observed among the NHWs (2.9%/year; 95%CI, 2.2%-3.7%). Incidence among NHWs increased in most U.S. states, particularly in the Southeast. Increases were significantly greater among NHW females compared to males (3.6%/year vs 2.6%/year; Conclusion: The period of rapidly increasing OTC incidence among younger NHW females in the U.S. is tempering and giving way to greater increases among older females, suggesting that a birth cohort effect may have influenced previously observed trends. Recent increases among NHWs aged ≥ 50 of both sexes have matched or outpaced younger age groups. Continuing increases among older individuals, particularly females, will lead to a shift in the OTC patient profile over time.
Language	English
Publishing date	2023-09-22
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-3359293/v1
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Article ; Online: Addressing Community Needs During the Hurricane Response and Recovery Efforts Through Community Assessments for Public Health Emergency Response (CASPER)-United States Virgin Islands, 2017-2018.

Schnall, Amy Helene / Roth, Joseph Jay / Ellis, Brett / Seger, Krystal / Davis, Michelle / Ellis, Esther M

Disaster medicine and public health preparedness

2019 Volume 13, Issue 1, Page(s) 53–62

Abstract: Objectives: Two category 5 storms hit the US Virgin Islands (USVI) within 13 days of each other in September 2017. This caused an almost complete loss of power and devastated critical infrastructure such as the hospitals and airports METHODS: The USVI ... ...

Abstract	Objectives: Two category 5 storms hit the US Virgin Islands (USVI) within 13 days of each other in September 2017. This caused an almost complete loss of power and devastated critical infrastructure such as the hospitals and airports METHODS: The USVI Department of Health conducted 2 response Community Assessments for Public Health Emergency Response (CASPERs) in November 2017 and a recovery CASPER in February 2018. CASPER is a 2-stage cluster sampling method designed to provide household-based information about a community's needs in a timely, inexpensive, and representative manner. Results: Almost 70% of homes were damaged or destroyed, 81.2% of homes still needed repair, and 10.4% of respondents felt their home was unsafe to live in approximately 5 months after the storms. Eighteen percent of individual respondents indicated that their mental health was "not good" for 14 or more days in the past month, a significant increase from 2016. Conclusion: The CASPERs helped characterize the status and needs of residents after the devastating hurricanes and illustrate the evolving needs of the community and the progression of the recovery process. CASPER findings were shared with response and recovery partners to promote data-driven recovery efforts, improve the efficiency of the current response and recovery efforts, and strengthen emergency preparedness in USVI. (Disaster Med Public Health Preparedness. 2019;13:53-62).
MeSH term(s)	Civil Defense/methods ; Civil Defense/statistics & numerical data ; Cyclonic Storms/statistics & numerical data ; Disaster Planning/methods ; Disaster Planning/statistics & numerical data ; Health Services Needs and Demand ; Humans ; Psychometrics/instrumentation ; Psychometrics/methods ; Public Health/methods ; Public Health/standards ; Public Health/statistics & numerical data ; United States Virgin Islands
Language	English
Publishing date	2019-03-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2375268-3
ISSN	1938-744X ; 1935-7893
ISSN (online)	1938-744X
ISSN	1935-7893
DOI	10.1017/dmp.2019.6
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Article ; Online: Anaphylaxis: A 2023 practice parameter update.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

2023 Volume 132, Issue 2, Page(s) 124–176

Abstract: This practice parameter update focuses on 7 areas in which there are new evidence and new recommendations. Diagnostic criteria for anaphylaxis have been revised, and patterns of anaphylaxis are defined. Measurement of serum tryptase is important for ... ...

Abstract	This practice parameter update focuses on 7 areas in which there are new evidence and new recommendations. Diagnostic criteria for anaphylaxis have been revised, and patterns of anaphylaxis are defined. Measurement of serum tryptase is important for diagnosis of anaphylaxis and to identify underlying mast cell disorders. In infants and toddlers, age-specific symptoms may differ from older children and adults, patient age is not correlated with reaction severity, and anaphylaxis is unlikely to be the initial reaction to an allergen on first exposure. Different community settings for anaphylaxis require specific measures for prevention and treatment of anaphylaxis. Optimal prescribing and use of epinephrine autoinjector devices require specific counseling and training of patients and caregivers, including when and how to administer the epinephrine autoinjector and whether and when to call 911. If epinephrine is used promptly, immediate activation of emergency medical services may not be required if the patient experiences a prompt, complete, and durable response. For most medical indications, the risk of stopping or changing beta-blocker or angiotensin-converting enzyme inhibitor medication may exceed the risk of more severe anaphylaxis if the medication is continued, especially in patients with insect sting anaphylaxis. Evaluation for mastocytosis, including a bone marrow biopsy, should be considered for adult patients with severe insect sting anaphylaxis or recurrent idiopathic anaphylaxis. After perioperative anaphylaxis, repeat anesthesia may proceed in the context of shared decision-making and based on the history and results of diagnostic evaluation with skin tests or in vitro tests when available, and supervised challenge when necessary.
MeSH term(s)	Adult ; Humans ; Child ; Adolescent ; Anaphylaxis/diagnosis ; Anaphylaxis/drug therapy ; Anaphylaxis/prevention & control ; Insect Bites and Stings/drug therapy ; Epinephrine/therapeutic use ; Mastocytosis/diagnosis ; Allergens
Chemical Substances	Epinephrine (YKH834O4BH) ; Allergens
Language	English
Publishing date	2023-12-18
Publishing country	United States
Document type	Practice Guideline
ZDB-ID	1228189-x
ISSN	1534-4436 ; 0003-4738 ; 1081-1206
ISSN (online)	1534-4436
ISSN	0003-4738 ; 1081-1206
DOI	10.1016/j.anai.2023.09.015
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Article ; Online: Feasibility of Defibrillation and Pacing Without Transvenous Leads in a Combined MICRA and S-ICD System Following Lead Extraction.

Montgomery, Jay A / Orton, Jody M / Ellis, Christopher R

Journal of cardiovascular electrophysiology

2016 Volume 28, Issue 2, Page(s) 233–234

MeSH term(s)	Aged ; Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/therapy ; Cardiac Pacing, Artificial ; Defibrillators, Implantable ; Device Removal/methods ; Electric Countershock/instrumentation ; Female ; Heart Block/complications ; Heart Block/diagnosis ; Heart Block/physiopathology ; Heart Block/therapy ; Humans ; Pacemaker, Artificial ; Prosthesis Design ; Treatment Outcome
Language	English
Publishing date	2016-11-08
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1025989-2
ISSN	1540-8167 ; 1045-3873
ISSN (online)	1540-8167
ISSN	1045-3873
DOI	10.1111/jce.13111
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