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  1. Book ; Online: Utilizing dataset affinity prediction in object detection to assess training data

    Becker, Stefan / Bayer, Jens / Hug, Ronny / Hübner, Wolfgang / Arens, Michael

    2023  

    Abstract: Data pooling offers various advantages, such as increasing the sample size, improving generalization, reducing sampling bias, and addressing data sparsity and quality, but it is not straightforward and may even be counterproductive. Assessing the ... ...

    Abstract Data pooling offers various advantages, such as increasing the sample size, improving generalization, reducing sampling bias, and addressing data sparsity and quality, but it is not straightforward and may even be counterproductive. Assessing the effectiveness of pooling datasets in a principled manner is challenging due to the difficulty in estimating the overall information content of individual datasets. Towards this end, we propose incorporating a data source prediction module into standard object detection pipelines. The module runs with minimal overhead during inference time, providing additional information about the data source assigned to individual detections. We show the benefits of the so-called dataset affinity score by automatically selecting samples from a heterogeneous pool of vehicle datasets. The results show that object detectors can be trained on a significantly sparser set of training samples without losing detection accuracy.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2023-11-16
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Efficacy of Antihypertensive Drugs of Different Classes After Renal Denervation in Spontaneously Hypertensive Rats.

    Hohl, Mathias / Lauder, Lucas / Sevimli, Özlem / Tokcan, Mert / Wagmann, Lea / Götzinger, Felix / Schneider, Clara / Hübner, Ulrich / Lehnert, Ulrike / Meyer, Markus R / Böhm, Michael / Mahfoud, Felix

    Hypertension (Dallas, Tex. : 1979)

    2023  Volume 80, Issue 6, Page(s) e90–e100

    Abstract: Background: Renal denervation (RDN) lowers blood pressure (BP) in patients with uncontrolled hypertension. Limited data exist on the effectiveness of different antihypertensive medications following RDN on BP and maladaptive cardiac phenotypes.: ... ...

    Abstract Background: Renal denervation (RDN) lowers blood pressure (BP) in patients with uncontrolled hypertension. Limited data exist on the effectiveness of different antihypertensive medications following RDN on BP and maladaptive cardiac phenotypes.
    Methods: Eighty-nine male spontaneously hypertensive rats with continuous BP recording underwent RDN or sham operation. Ten days postsurgery, spontaneously hypertensive rats were randomized to receive no antihypertensive medication, amlodipine, olmesartan, hydrochlorothiazide, bisoprolol, doxazosin, or moxonidine for 28 days. Cardiac remodeling was determined histologically, and activation of the renin-angiotensin-aldosterone system was explored.
    Results: Before initiation of antihypertensive drugs, RDN reduced mean arterial pressure (-12.6 mm Hg [95% CI, -14.4 to -10.8];
    Conclusions: Following RDN, treatment with amlodipine and olmesartan resulted in the largest BP reduction. Antihypertensive medications mediated heterogeneous effects on renin-angiotensin-aldosterone system activity and cardiac remodeling.
    MeSH term(s) Animals ; Male ; Rats ; Aldosterone ; Amlodipine/pharmacology ; Amlodipine/therapeutic use ; Antihypertensive Agents/pharmacology ; Antihypertensive Agents/therapeutic use ; Bisoprolol/pharmacology ; Bisoprolol/therapeutic use ; Blood Pressure/physiology ; Cardiomyopathies ; Denervation/methods ; Doxazosin/pharmacology ; Doxazosin/therapeutic use ; Hydrochlorothiazide/pharmacology ; Hydrochlorothiazide/therapeutic use ; Hypertension/drug therapy ; Hypertension/surgery ; Kidney ; Rats, Inbred SHR ; Renin ; Sympathectomy
    Chemical Substances Aldosterone (4964P6T9RB) ; Amlodipine (1J444QC288) ; Antihypertensive Agents ; Bisoprolol (Y41JS2NL6U) ; Doxazosin (NW1291F1W8) ; Hydrochlorothiazide (0J48LPH2TH) ; Renin (EC 3.4.23.15)
    Language English
    Publishing date 2023-03-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.122.20756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: B\'ezier Curve Gaussian Processes

    Hug, Ronny / Becker, Stefan / Hübner, Wolfgang / Arens, Michael / Beyerer, Jürgen

    2022  

    Abstract: Probabilistic models for sequential data are the basis for a variety of applications concerned with processing timely ordered information. The predominant approach in this domain is given by neural networks, which incorporate either stochastic units or ... ...

    Abstract Probabilistic models for sequential data are the basis for a variety of applications concerned with processing timely ordered information. The predominant approach in this domain is given by neural networks, which incorporate either stochastic units or components. This paper proposes a new probabilistic sequence model building on probabilistic B\'ezier curves. Using Gaussian distributed control points, these parametric curves pose a special case for Gaussian processes (GP). Combined with a Mixture Density network, Bayesian conditional inference can be performed without the need for mean field variational approximation or Monte Carlo simulation, which is a requirement of common approaches. For assessing this hybrid model's viability, it is applied to an exemplary sequence prediction task. In this case the model is used for pedestrian trajectory prediction, where a generated prediction also serves as a GP prior. Following this, the initial prediction can be refined using the GP framework by calculating different posterior distributions, in order to adapt more towards a given observed trajectory segment.
    Keywords Statistics - Machine Learning ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2022-05-03
    Publishing country us
    Document type Book ; Online
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  4. Article ; Online: Ambulantisierung in der Pneumologie – eine wissenschaftliche Analyse und ein Positionspapier der DGP.

    Darwiche, Kaid / Randerath, Winfried / Hübner, Ralf-Harto / Rathmayer, Markus / Tiefgraber, Melanie / Borass, Volkmar / Piening, Anne / Hagmeyer, Lars / Hetzel, Juergen / Eberhardt, Ralf / Gesierich, Wolfgang / Unnewehr, Markus / Boeing, Sebastian / Wilke, Michael / Herth, Felix / Bauer, Torsten

    Pneumologie (Stuttgart, Germany)

    2024  

    Abstract: Introduction:  The ambulantization of patient care that were previously provided as inpatient service is one of the goals of the current reform in the German healthcare system. In pulmonology, this particularly applies to endoscopic procedures. However, ...

    Title translation Outpatient care in pulmonology - a scientific analysis and a position paper of the German Society of Respiratory Medicine (DGP).
    Abstract Introduction:  The ambulantization of patient care that were previously provided as inpatient service is one of the goals of the current reform in the German healthcare system. In pulmonology, this particularly applies to endoscopic procedures. However, the real costs of endoscopic services, which form the basis for the calculation of a future so called hybrid DRG or in the AOP catalog, are unclear.
    Methods:  After selection of use cases including endoscopic procedures which can be performed on an outpatient basis by a committee of experts the appropriate DRGs were identified from the § 21-KHEntgG data for 2022 published by the Institute for the Hospital Remuneration System (InEK). The costs were calculated from the respective InEK cost matrix added by the calculated material costs.
    Results:  The use cases suitable for outpatient treatment were systematic endobronchial ultrasound (EBUS) with transbronchial needle aspiration (calculated costs € 2,175.60 without or € 3,315.60 including PET/CT), navigation-assisted bronchoscopy for peripheral lesions (depending on the methodology € 2,870.23 to €4,120.23) and diagnostic (flexible) bronchoscopy (€ 1,121.02).
    Conclusion:  Outpatient treatment of endoscopic procedures that were previously performed inpatient is possible and necessary, and the costs calculated in this publication can form a reliable basis for appropriate reimbursement. Together with a structural quality that has been transformed to outpatient service and cross-sector cooperation, continued high-quality care for pneumological patients can be ensured.
    Language German
    Publishing date 2024-03-20
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/a-2279-7787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.142: Show issues Location:
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  5. Book ; Online: Quantifying the Complexity of Standard Benchmarking Datasets for Long-Term Human Trajectory Prediction

    Hug, Ronny / Becker, Stefan / Hübner, Wolfgang / Arens, Michael

    2020  

    Abstract: Methods to quantify the complexity of trajectory datasets are still a missing piece in benchmarking human trajectory prediction models. In order to gain a better understanding of the complexity of trajectory prediction tasks and following the intuition, ... ...

    Abstract Methods to quantify the complexity of trajectory datasets are still a missing piece in benchmarking human trajectory prediction models. In order to gain a better understanding of the complexity of trajectory prediction tasks and following the intuition, that more complex datasets contain more information, an approach for quantifying the amount of information contained in a dataset from a prototype-based dataset representation is proposed. The dataset representation is obtained by first employing a non-trivial spatial sequence alignment, which enables a subsequent learning vector quantization (LVQ) stage. A large-scale complexity analysis is conducted on several human trajectory prediction benchmarking datasets, followed by a brief discussion on indications for human trajectory prediction and benchmarking.
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Subject code 004 ; 006
    Publishing date 2020-05-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: A Short Note on Analyzing Sequence Complexity in Trajectory Prediction Benchmarks

    Hug, Ronny / Becker, Stefan / Hübner, Wolfgang / Arens, Michael

    2020  

    Abstract: The analysis and quantification of sequence complexity is an open problem frequently encountered when defining trajectory prediction benchmarks. In order to enable a more informative assembly of a data basis, an approach for determining a dataset ... ...

    Abstract The analysis and quantification of sequence complexity is an open problem frequently encountered when defining trajectory prediction benchmarks. In order to enable a more informative assembly of a data basis, an approach for determining a dataset representation in terms of a small set of distinguishable prototypical sub-sequences is proposed. The approach employs a sequence alignment followed by a learning vector quantization (LVQ) stage. A first proof of concept on synthetically generated and real-world datasets shows the viability of the approach.

    Comment: Submitted to LHMP2020 Workshop
    Keywords Computer Science - Machine Learning ; Computer Science - Robotics
    Publishing date 2020-03-27
    Publishing country us
    Document type Book ; Online
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  7. Article: Wissen, wie man es (noch) besser machen kann? Qualitätsmanagement in der Krankenhausverwaltung

    Hübner, Michael / Mathias, Katrin / Schmeißer, Rainer

    KU-Gesundheitsmanagement

    2020  Volume 89, Issue 10, Page(s) 38

    Language German
    Document type Article
    ZDB-ID 2420760-3
    ISSN 1867-9269
    Database Current Contents Medicine

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  8. Article ; Online: Time pressure affects the efficiency of perceptual processing in decisions under conflict.

    Dambacher, Michael / Hübner, Ronald

    Psychological research

    2014  Volume 79, Issue 1, Page(s) 83–94

    Abstract: The negative correlation between speed and accuracy in perceptual decision making is often explained as a tradeoff, where lowered decision boundaries under time pressure result in faster but more error-prone responses. Corresponding implementations in ... ...

    Abstract The negative correlation between speed and accuracy in perceptual decision making is often explained as a tradeoff, where lowered decision boundaries under time pressure result in faster but more error-prone responses. Corresponding implementations in sequential sampling models confirmed the success of this account, which has led to the prevalent assumption that a second component of decision making, the efficiency of perceptual processing, is largely independent from temporal demands. To test the generality of this claim, we examined time pressure effects on decisions under conflict. Data from a flanker task were fit with a sequential sampling model that incorporates two successive phases of response selection, driven by the output of an early and late stage of stimulus selection, respectively. The fits revealed the canonical decrease of response boundaries with increasing time pressure. In addition, time pressure reduced the duration of non-decisional processes and impaired the early stage of stimulus selection, together with the subsequent first phase of response selection. The results show that the relation between speed and accuracy not only relies on the strategic adjustment of response boundaries but involves variations of processing efficiency. The findings support recent evidence of drift rate modulations in response to time pressure in simple perceptual decisions and confirm their validity in the context of more complex tasks.
    MeSH term(s) Adolescent ; Adult ; Conflict, Psychological ; Decision Making/physiology ; Female ; Humans ; Male ; Reaction Time/physiology ; Time Factors ; Young Adult
    Language English
    Publishing date 2014-02-02
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1463034-5
    ISSN 1430-2772 ; 0340-0727
    ISSN (online) 1430-2772
    ISSN 0340-0727
    DOI 10.1007/s00426-014-0542-z
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  9. Article ; Online: Controlled Self-Assembly of Gold Nanotetrahedra into Quasicrystals and Complex Periodic Supracrystals.

    Wang, Yi / Chen, Jun / Li, Ruipeng / Götz, Alexander / Drobek, Dominik / Przybilla, Thomas / Hübner, Sabine / Pelz, Philipp / Yang, Lin / Apeleo Zubiri, Benjamin / Spiecker, Erdmann / Engel, Michael / Ye, Xingchen

    Journal of the American Chemical Society

    2023  Volume 145, Issue 32, Page(s) 17902–17911

    Abstract: The self-assembly of shape-anisotropic nanocrystals into large-scale structures is a versatile and scalable approach to creating multifunctional materials. The tetrahedral geometry is ubiquitous in natural and manmade materials, yet regular tetrahedra ... ...

    Abstract The self-assembly of shape-anisotropic nanocrystals into large-scale structures is a versatile and scalable approach to creating multifunctional materials. The tetrahedral geometry is ubiquitous in natural and manmade materials, yet regular tetrahedra present a formidable challenge in understanding their self-assembly behavior as they do not tile space. Here, we report diverse supracrystals from gold nanotetrahedra including the quasicrystal (QC) and the dimer packing predicted more than a decade ago and hitherto unknown phases. We solve the complex three-dimensional (3D) structure of the QC by a combination of electron microscopy, tomography, and synchrotron X-ray scattering. Nanotetrahedron vertex sharpness, surface ligands, and assembly conditions work in concert to regulate supracrystal structure. We also discover that the surface curvature of supracrystals can induce structural changes of the QC tiling and eventually, for small supracrystals with high curvature, stabilize a hexagonal approximant. Our findings bridge the gap between computational design and experimental realization of soft matter assemblies and demonstrate the importance of accurate control over nanocrystal attributes and the assembly conditions to realize increasingly complex nanopolyhedron supracrystals.
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c05299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  10. Book: Internationalisierung von Gesundheitsdienstleistungen - Patientenimport und Serviceexport, Teilvorhaben: Management von Patienten- und Serviceströmen

    Hübner, Michael R

    Abschlussbericht des BMBF-Projektes

    2008  

    Author's details Michael R. Hübner
    Language German
    Size 44, [77] Bl., graph. Darst., Kt.
    Publisher SWZ
    Publishing place Gelsenkirchen
    Document type Book
    Note Förderkennzeichen BMBF 01 HQ 0512. - Verbund-Nr. 01038386 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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