LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 73

Search options

  1. Book: Bacterial chromatin

    Dame, Remus

    methods and protocols

    (Methods in molecular biology ; 1837 ; Springer protocols)

    2018  

    Author's details edited by Remus T. Dame (Leiden Institute of Chemistry and Centre for Microbial Cell Biology, Leiden University, Leiden, the Netherlands)
    Series title Methods in molecular biology ; 1837
    Springer protocols
    Collection
    Language English
    Size xi, 419 Seiten, Illustrationen, Diagramme
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019861545
    ISBN 978-1-4939-8674-3 ; 9781493986750 ; 1-4939-8674-0 ; 1493986759
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -1837- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Bacterial chromatin

    Dame, Remus T.

    2010  

    Author's details Remus T. Dame ... ed
    Language English
    Size X, 448 S. : Ill.-, graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT016287791
    ISBN 978-90-481-3472-4 ; 9789048134731 ; 90-481-3472-2 ; 9048134730
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 1505 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Special Issue: Role of Bacterial Chromatin in Environmental Sensing, Adaptation and Evolution.

    Dame, Remus T

    Microorganisms

    2021  Volume 9, Issue 11

    Abstract: A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [ ... ]. ...

    Abstract A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [...].
    Language English
    Publishing date 2021-11-22
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9112406
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Special Issue

    Remus T. Dame

    Microorganisms, Vol 9, Iss 2406, p

    Role of Bacterial Chromatin in Environmental Sensing, Adaptation and Evolution

    2021  Volume 2406

    Abstract: A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [.] ...

    Abstract A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [.]
    Keywords n/a ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Special Issue: Role of Bacterial Chromatin in Environmental Sensing, Adaptation and Evolution

    Dame, Remus T.

    Microorganisms. 2021 Nov. 22, v. 9, no. 11

    2021  

    Abstract: A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [ ... ] ...

    Abstract A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [...]
    Keywords bacteria ; chromatin ; evolution ; genome
    Language English
    Dates of publication 2021-1122
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9112406
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Three-dimensional chromosome re-modelling: The integral mechanism of transcription regulation in bacteria.

    Rashid, Fatema-Zahra M / Dame, Remus T

    Molecular microbiology

    2023  Volume 120, Issue 1, Page(s) 60–70

    Abstract: Nucleoid-associated proteins (NAPs) are architectural proteins of the bacterial chromosome and transcription factors that dynamically organise the chromosome and regulate gene expression in response to physicochemical environmental signals. While the ... ...

    Abstract Nucleoid-associated proteins (NAPs) are architectural proteins of the bacterial chromosome and transcription factors that dynamically organise the chromosome and regulate gene expression in response to physicochemical environmental signals. While the architectural and regulatory functions of NAPs have been verified independently, the coupling between these functions in vivo has not been conclusively proven. Here we describe a model NAP - histone-like nucleoid structuring protein (H-NS) - as a coupled sensor-effector that directly regulates gene expression by chromatin re-modelling in response to physicochemical environmental signals. We outline how H-NS-binding partners and post-translational modifications modulate the role of H-NS as a transcription factor by influencing its DNA structuring properties. We consolidate our ideas in models of how H-NS may regulate the expression of the proVWX and hlyCABD operons by chromatin re-modelling. The interplay between chromosome structure and gene expression may be a common - but, at present, under-appreciated - concept of transcription regulation in bacteria.
    MeSH term(s) Gene Expression Regulation ; Chromatin Assembly and Disassembly ; Transcription Factors/genetics ; Chromosomes, Bacterial/genetics ; Bacteria/genetics ; Histones ; Chromatin
    Chemical Substances Transcription Factors ; Histones ; Chromatin
    Language English
    Publishing date 2023-04-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 619315-8
    ISSN 1365-2958 ; 0950-382X
    ISSN (online) 1365-2958
    ISSN 0950-382X
    DOI 10.1111/mmi.15062
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2502: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Rok from B. subtilis: Bridging genome structure and transcription regulation.

    Erkelens, Amanda M / van Erp, Bert / Meijer, Wilfried J J / Dame, Remus T

    Molecular microbiology

    2024  

    Abstract: Bacterial genomes are folded and organized into compact yet dynamic structures, called nucleoids. Nucleoid orchestration involves many factors at multiple length scales, such as nucleoid-associated proteins and liquid-liquid phase separation, and has to ... ...

    Abstract Bacterial genomes are folded and organized into compact yet dynamic structures, called nucleoids. Nucleoid orchestration involves many factors at multiple length scales, such as nucleoid-associated proteins and liquid-liquid phase separation, and has to be compatible with replication and transcription. Possibly, genome organization plays an intrinsic role in transcription regulation, in addition to classical transcription factors. In this review, we provide arguments supporting this view using the Gram-positive bacterium Bacillus subtilis as a model. Proteins BsSMC, HBsu and Rok all impact the structure of the B. subtilis chromosome. Particularly for Rok, there is compelling evidence that it combines its structural function with a role as global gene regulator. Many studies describe either function of Rok, but rarely both are addressed at the same time. Here, we review both sides of the coin and integrate them into one model. Rok forms unusually stable DNA-DNA bridges and this ability likely underlies its repressive effect on transcription by either preventing RNA polymerase from binding to DNA or trapping it inside DNA loops. Partner proteins are needed to change or relieve Rok-mediated gene repression. Lastly, we investigate which features characterize H-NS-like proteins, a family that, at present, lacks a clear definition.
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 619315-8
    ISSN 1365-2958 ; 0950-382X
    ISSN (online) 1365-2958
    ISSN 0950-382X
    DOI 10.1111/mmi.15250
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2502: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Chromosome Conformation Capture in Bacteria and Archaea.

    Rashid, Fatema-Zahra M / Detmar, Laurien / Dame, Remus T

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2516, Page(s) 1–28

    Abstract: The three-dimensional structure of the chromosome is encoded within its sequence and regulates activities such as replication and transcription. This necessitates the study of the spatial organization of the chromosome in relation to the underlying ... ...

    Abstract The three-dimensional structure of the chromosome is encoded within its sequence and regulates activities such as replication and transcription. This necessitates the study of the spatial organization of the chromosome in relation to the underlying sequence. Chromosome conformation capture (3C) techniques are proximity ligation-based approaches that simplify the three-dimensional architecture of the chromosome into a one-dimensional library of hybrid ligation junctions. Deciphering the information contained in these libraries resolves chromosome architecture in a sequence-specific manner. This chapter describes the preparation of 3C libraries for bacteria and archaea. It details how the three-dimensional architecture of local chromatin can be extracted from the 3C library using qPCR (3C-qPCR), and it summarizes the processing of 3C libraries for next-generation sequencing (3C-Seq) for a study of global chromosome organization.
    MeSH term(s) Archaea/genetics ; Bacteria/genetics ; Chromatin/genetics ; Chromosomes/genetics ; High-Throughput Nucleotide Sequencing/methods ; Nucleic Acid Conformation
    Chemical Substances Chromatin
    Language English
    Publishing date 2022-08-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2413-5_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Direct visualization of the effect of DNA structure and ionic conditions on HU-DNA interactions.

    Lin, Szu-Ning / Dame, Remus T / Wuite, Gijs J L

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 18492

    Abstract: Architectural DNA-binding proteins are involved in many important DNA transactions by virtue of their ability to change DNA conformation. Histone-like protein from E. coli strain U93, HU, is one of the most studied bacterial architectural DNA-binding ... ...

    Abstract Architectural DNA-binding proteins are involved in many important DNA transactions by virtue of their ability to change DNA conformation. Histone-like protein from E. coli strain U93, HU, is one of the most studied bacterial architectural DNA-binding proteins. Nevertheless, there is still a limited understanding of how the interactions between HU and DNA are affected by ionic conditions and the structure of DNA. Here, using optical tweezers in combination with fluorescent confocal imaging, we investigated how ionic conditions affect the interaction between HU and DNA. We directly visualized the binding and the diffusion of fluorescently labelled HU dimers on DNA. HU binds with high affinity and exhibits low mobility on the DNA in the absence of Mg
    MeSH term(s) DNA/chemistry ; DNA/metabolism ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/metabolism ; Histones/chemistry ; Histones/metabolism ; Magnesium/chemistry ; Magnesium/metabolism ; Nucleic Acid Conformation ; Optical Tweezers ; Osmolar Concentration ; Protein Binding ; Protein Multimerization
    Chemical Substances Escherichia coli Proteins ; Histones ; DNA (9007-49-2) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 2021-09-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-97763-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Specific DNA binding of archaeal histones HMfA and HMfB.

    Erkelens, Amanda M / Henneman, Bram / van der Valk, Ramon A / Kirolos, Nancy C S / Dame, Remus T

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1166608

    Abstract: ... of alternating A/T and G/C motifs. These motifs are also present on the artificial sequence "Clone20," a high ...

    Abstract In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence specificity, they bind preferentially to DNA containing repeats of alternating A/T and G/C motifs. These motifs are also present on the artificial sequence "Clone20," a high-affinity model sequence for binding of the histones from
    Language English
    Publishing date 2023-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1166608
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top