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  1. Article ; Online: Utility of Intracoronary Acetylcholine Provocation Testing in Inducing Atrial Fibrillation with Preexcitation Followed by Ventricular Fibrillation in a Patient with Wolff-Parkinson-White Syndrome: A Case Report.

    Saito, Akira / Mochida, Chisaki / Mizuno, Atsushi / Masuda, Keita

    Internal medicine (Tokyo, Japan)

    2024  

    Abstract: A 20-year-old man was resuscitated after ventricular fibrillation (VF). Electrocardiography revealed Wolff-Parkinson-White (WPW) syndrome. Intracoronary acetylcholine provocation testing was performed to induce VF secondary to the coronary vasospasm. The ...

    Abstract A 20-year-old man was resuscitated after ventricular fibrillation (VF). Electrocardiography revealed Wolff-Parkinson-White (WPW) syndrome. Intracoronary acetylcholine provocation testing was performed to induce VF secondary to the coronary vasospasm. The administration of acetylcholine to the coronary artery induced atrial fibrillation (AF) with pre-excitation, followed by VF without coronary vasospasm. Electrophysiological studies revealed an accessory pathway managed by catheter ablation. Subsequent intracoronary acetylcholine provocation testing (ACH test) induced the occurrence of AF without preexcitation. To our knowledge, this case report is the first to demonstrate the utility of the ACH test in confirming WPW syndrome as a cause of VF.
    Language English
    Publishing date 2024-02-19
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.3000-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 240: Show issues Location:
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  2. Article ; Online: Persistent trigeminal artery variant and presumed ophthalmic artery simultaneously arising from the inferolateral trunk incidentally diagnosed by magnetic resonance angiography.

    Uchino, Akira / Masuda, Hiroaki

    Surgical and radiologic anatomy : SRA

    2023  Volume 46, Issue 1, Page(s) 47–50

    Abstract: Purpose: To describe a case of persistent trigeminal artery variant (PTAV) and presumed ophthalmic artery (OA) simultaneously arising from the inferolateral trunk (ILT).: Methods: A 53-year-old woman with an initial episode of convulsion underwent ... ...

    Abstract Purpose: To describe a case of persistent trigeminal artery variant (PTAV) and presumed ophthalmic artery (OA) simultaneously arising from the inferolateral trunk (ILT).
    Methods: A 53-year-old woman with an initial episode of convulsion underwent cranial magnetic resonance imaging (MRI) and MR angiography (MRA) of the intracranial region for the evaluation of brain and vascular lesions. The MR machine was a 3-T scanner.
    Results: MRI revealed no pathological brain lesions. On MRA, the left anterior inferior cerebellar artery (AICA) arose from the cavernous segment of the internal carotid artery (ICA), indicative of the PTAV. The arising point was more distal than the usual point, and the presumed OA also arose simultaneously from the short common trunk, which was considered the ILT.
    Conclusion: There are two types of PTA: lateral (usual) and medial (intrasellar) PTA. The lateral-type PTA and PTAV arise from the ICA of the distal precavernous-proximal cavernous segment and take a course similar to that of the posterior fossa. The medial type arises slightly more in the distal cavernous segment than in the lateral type. The OA rarely arises from the cavernous segment of the ICA and enters the orbit via the superior orbital fissure. The origin of this type of OA is considered to be the ILT. We herein report a case of a PTAV and presumed OA arising simultaneously from an ILT. No similar case has been reported in the relevant English language literature.
    MeSH term(s) Female ; Humans ; Middle Aged ; Ophthalmic Artery/diagnostic imaging ; Magnetic Resonance Angiography/methods ; Magnetic Resonance Imaging ; Head ; Brain ; Carotid Artery, Internal/diagnostic imaging
    Language English
    Publishing date 2023-11-17
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 632839-8
    ISSN 1279-8517 ; 0930-312X ; 0930-1038
    ISSN (online) 1279-8517
    ISSN 0930-312X ; 0930-1038
    DOI 10.1007/s00276-023-03264-y
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1456: Show issues Location:
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  3. Article ; Online: Effects of Thioureas, Inhibitors of Melanogenesis, on Lens Transdifferentiation of Cultured Chicken Embryonic Retinal Pigment Cells: (retinal pigment cells/thioureas/transdifferentiation/cell culture).

    Masuda, Akira / Eguchi, Goro

    Development, growth & differentiation

    2023  Volume 24, Issue 6, Page(s) 589–599

    Abstract: The effects of phenylthiourea (PTU) and its analogues on chick embryonic pigmented epithelial cells (PECs) in culture were studied to elucidate the correlation between inhibition of melanogenesis of PECs and enhancement of their transdifferentiation into ...

    Abstract The effects of phenylthiourea (PTU) and its analogues on chick embryonic pigmented epithelial cells (PECs) in culture were studied to elucidate the correlation between inhibition of melanogenesis of PECs and enhancement of their transdifferentiation into lens cells. Both 0.25-0.5 mM PTU and 0.1 mM alpha-naphthylthiourea (ANTU) effectively inhibited melanogenesis of PECs and stimulated their transdifferentiation into lens cells at the same time. Thiourea (TU) also inhibited melanogenesis at a much higher concentration (4 mM), but did not stimulate the lens transdifferentiation at all. Methylthiourea (MTU), on the other hand, did not inhibit melanogenesis, but stimulated the lens transdifferentiation. Testicular hyaluronidase effectively amplified the above-mentioned stimulating effects of thioureas without their altering optimum concentrations, although this enzyme itself never enhanced the lens transdifferentiation of PECs but suppressed their melanogenesis at a concentration of 100 U/ml medium, onward. These results suggest that the suppression of melanogenesis of PECs by PTU or its analogues does not directly correlate with their transdifferentiation into lens cells. The possible mode of thiourea actions on the lens transdifferentiation of PECs cultured in vitro is discussed.
    Language English
    Publishing date 2023-06-06
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 280433-5
    ISSN 1440-169X ; 0012-1592
    ISSN (online) 1440-169X
    ISSN 0012-1592
    DOI 10.1111/j.1440-169X.1982.00589.x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 194: Show issues Location:
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  4. Article: Therapeutic Effects of CDK4/6 Inhibitors in Gastric and Colonic Metastases From Breast Cancer: A Case Report.

    Sasaki, Akinori / Masuda, Shuko / Yoshioka, Tsubasa / Saito, Akira / Motomura, Yasuaki

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52765

    Abstract: Breast cancer often metastasizes to the lungs, bones, liver, and brain; however, gastric and colonic metastases from breast cancer are rare. Nevertheless, here, we present the case of a 50-year-old woman diagnosed with recurrent breast cancer, exhibiting ...

    Abstract Breast cancer often metastasizes to the lungs, bones, liver, and brain; however, gastric and colonic metastases from breast cancer are rare. Nevertheless, here, we present the case of a 50-year-old woman diagnosed with recurrent breast cancer, exhibiting gastric and colonic metastases that were detected when she experienced intermittent abdominal pain. The differentiation between primary gastric cancer and metastasis from breast cancer was made through immunohistochemical staining. The patient underwent treatment with palbociclib, a cyclin-dependent kinase (CDK)4/6 inhibitor, and anastrozole, with no significant adverse effects. Subsequent upper and lower endoscopic examinations following the initiation of these treatments revealed tumor shrinkage in both gastric and colonic metastases. This case report presents the first instance in which morphological changes in gastrointestinal metastasis induced by CDK4/6 inhibitors could be evaluated.
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52765
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  5. Article ; Online: Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid.

    Masuda, Yasutaka / Yamazaki, Sho / Honda, Akira / Masamoto, Yosuke / Kurokawa, Mineo

    Annals of hematology

    2024  Volume 103, Issue 4, Page(s) 1403–1407

    Abstract: Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after ... ...

    Abstract Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before she presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.
    MeSH term(s) Female ; Humans ; Middle Aged ; Bronchiolitis Obliterans Syndrome ; Graft vs Host Disease/drug therapy ; Graft vs Host Disease/etiology ; Adrenal Cortex Hormones/therapeutic use ; Pleural Effusion/drug therapy ; Pleural Effusion/etiology ; Tacrolimus/therapeutic use ; Hematopoietic Stem Cell Transplantation/adverse effects ; Chronic Disease
    Chemical Substances Adrenal Cortex Hormones ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2024-01-29
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-024-05643-w
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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.181: Show issues Location:
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  6. Article ; Online: Multisystem Inflammatory Syndrome in Clinically Mild Encephalitis/Encephalopathy with Reversible Splenial Lesion.

    Ishikawa, Kazu / Hayakawa, Itaru / Masuda, Hiroshi / Kubota, Mitsuru / Ishiguro, Akira

    Indian journal of pediatrics

    2023  Volume 90, Issue 9, Page(s) 940–941

    MeSH term(s) Humans ; Brain Diseases/diagnostic imaging ; Brain Diseases/etiology ; Encephalitis/diagnosis ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-04-21
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04542-8
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    Zs.A 826: Show issues Location:
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  7. Article: Effect of propofol on salivary secretion from the submandibular, sublingual, and labial glands during intravenous sedation.

    Masuda, Keisuke / Furuyama, Akira / Ohsuga, Kenji / Abe, Shota / Kawaai, Hiroyoshi

    Journal of dental anesthesia and pain medicine

    2023  Volume 23, Issue 3, Page(s) 153–162

    Abstract: Background: Recent animal studies have suggested the role of GABA type A (GABA-: Methods: Twenty healthy male volunteers participated in the study. They received a loading dose of propofol 6 mg/kg/h for 10 min, followed by 3 mg/kg/h for 15 min. ... ...

    Abstract Background: Recent animal studies have suggested the role of GABA type A (GABA-
    Methods: Twenty healthy male volunteers participated in the study. They received a loading dose of propofol 6 mg/kg/h for 10 min, followed by 3 mg/kg/h for 15 min. Salivary flow rates in the submandibular, sublingual, and labial glands were measured before, during, and after propofol infusion, and amylase activity was measured in the saliva from the submandibular and sublingual glands.
    Results: We found that the salivary flow rates in the submandibular, sublingual, and labial glands significantly decreased during intravenous sedation with propofol (P < 0.01). Similarly, amylase activity in the saliva from the submandibular and sublingual glands was significantly decreased (P < 0.01).
    Conclusion: It can be concluded that intravenous sedation with propofol decreases salivary secretion in the submandibular, sublingual, and labial glands via the GABA-
    Language English
    Publishing date 2023-05-26
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3024253-8
    ISSN 2383-9317 ; 2383-9309
    ISSN (online) 2383-9317
    ISSN 2383-9309
    DOI 10.17245/jdapm.2023.23.3.153
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  8. Article ; Online: Metabolic changes contributing to large biomass production in the Arabidopsis ppGpp-accumulating mutant under nitrogen deficiency.

    Goto, Mina / Oikawa, Akira / Masuda, Shinji

    Planta

    2022  Volume 255, Issue 2, Page(s) 48

    Abstract: Main conclusion: The Arabidopsis ppGpp-overproducing mutant indicates a larger biomass than wild type by modulated amino-acid metabolism under nitrogen-limiting conditions. The regulatory nucleotide, guanosine 3', 5'-bis(pyrophosphate; ppGpp)-originally ...

    Abstract Main conclusion: The Arabidopsis ppGpp-overproducing mutant indicates a larger biomass than wild type by modulated amino-acid metabolism under nitrogen-limiting conditions. The regulatory nucleotide, guanosine 3', 5'-bis(pyrophosphate; ppGpp)-originally identified in Escherichia coli-controls gene expression and enzyme activities in the bacteria and plastids of plant cells. We recently reported that the ppGpp over-producing mutant of Arabidopsis thaliana had a larger shoot weight than wild type (WT), especially under nutrient-deficient conditions. However, the mechanisms behind the influence of ppGpp on plant growth and biomass remain elusive. To understand the impact of the ppGpp accumulation on plant growth, we characterized metabolic changes in the ppGpp-overproducing mutant upon transition from nitrogen-rich to nitrogen-limiting concentrations. We found that the fresh weight of the mutant was significantly larger than WT when the total nitrogen source (KNO
    MeSH term(s) Arabidopsis/genetics ; Biomass ; Escherichia coli ; Guanosine Tetraphosphate ; Nitrogen
    Chemical Substances Guanosine Tetraphosphate (33503-72-9) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2022-01-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 208909-9
    ISSN 1432-2048 ; 0032-0935 ; 1866-2749
    ISSN (online) 1432-2048
    ISSN 0032-0935 ; 1866-2749
    DOI 10.1007/s00425-022-03835-0
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    Z 46/303: Show issues

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  9. Article ; Online: Kawasaki Disease with Facial Nerve Palsy.

    Murata, Yo / Masuda, Hiroshi / Moroka, Shintaro / Yotani, Nobuyuki / Morimoto, Noriko / Kubota, Mitsuru / Ishiguro, Akira

    Indian journal of pediatrics

    2023  Volume 91, Issue 1, Page(s) 101

    MeSH term(s) Humans ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Facial Nerve ; Facial Paralysis/diagnosis ; Facial Paralysis/etiology ; Coronary Aneurysm
    Language English
    Publishing date 2023-09-02
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04835-y
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 826: Show issues Location:
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  10. Article ; Online: Nrf3 Functions Reversely as a Tumorigenic to an Antitumorigenic Transcription Factor in Obese Mice.

    Waku, Tsuyoshi / Iwami, Takuya / Masuda, Haruka / Hirose, Shuuhei / Aketa, Iori / Kobayashi, Akira

    The Tohoku journal of experimental medicine

    2022  

    Language English
    Publishing date 2022-11-03
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 123477-8
    ISSN 1349-3329 ; 0040-8727
    ISSN (online) 1349-3329
    ISSN 0040-8727
    DOI 10.1620/tjem.2022.J090
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