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  1. Article ; Online: The Diagnostic Conundrum of Felty Syndrome and T-Cell Large Granular Lymphocytic Leukemia.

    Onuorah, Nneoma / Abraham, Hrudya / Vashisht, Priyanka

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2020  Volume 27, Issue 8S, Page(s) S829–S831

    MeSH term(s) Arthritis, Rheumatoid ; Felty Syndrome/diagnosis ; Humans ; Leukemia, Large Granular Lymphocytic/diagnosis
    Language English
    Publishing date 2020-06-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000001421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Sump Syndrome: A Rare Long-Term Complication of Choledochoduodenostomy.

    Abraham, Hrudya / Thomas, Sajan / Srivastava, Amit

    Case reports in gastroenterology

    2017  Volume 11, Issue 2, Page(s) 428–433

    Abstract: Biliary sump syndrome is a rare condition. It is seen as a rare long-term complication in patients with a history of a side-to-side choledochoduodenostomy. In the era before endoscopic retrograde cholangiopancreatography, side-to-side ... ...

    Abstract Biliary sump syndrome is a rare condition. It is seen as a rare long-term complication in patients with a history of a side-to-side choledochoduodenostomy. In the era before endoscopic retrograde cholangiopancreatography, side-to-side choledochoduodenostomy was a common surgical procedure for the management of biliary obstruction. In the setting of a side-to-side choledochoduodenostomy, the bile does not drain through the distal common bile duct anymore. Therefore, the part of the common bile duct distal from the choledochoduodenostomy anastomosis consequently transforms into a poorly drained reservoir, making this so-called "sump" prone to accumulation of debris. These patients are prone to cholangitis. We present a 64-year-old man with a history of side-to-side choledochoduodenostomy who presented with manifestations of cholangitis. An endoscopic retrograde cholangiopancreatography confirmed a diagnosis of sump syndrome. The etiology, clinical manifestations, and treatment of biliary sump syndrome are discussed in this article.
    Language English
    Publishing date 2017-08-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000477335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): An Uncommon Manifestation of Systemic Lupus Erythematosus (SLE).

    Abraham, Hrudya / Kuzhively, Jose / Rizvi, Syed W

    The American journal of case reports

    2017  Volume 18, Page(s) 980–983

    Abstract: BACKGROUND Chronic inflammatory demyelinating polyneuropathy (CIDP) is an uncommon manifestation of systemic lupus erythematosus (SLE). We report a case of SLE presenting as CIDP and discuss the diagnosis, management, and prognosis of CIDP. CASE REPORT A ...

    Abstract BACKGROUND Chronic inflammatory demyelinating polyneuropathy (CIDP) is an uncommon manifestation of systemic lupus erythematosus (SLE). We report a case of SLE presenting as CIDP and discuss the diagnosis, management, and prognosis of CIDP. CASE REPORT A 40-year-old woman with a past medical history of SLE treated with hydroxychloroquine presented with bilateral, progressive, ascending, sensory and motor neuropathy. Physical examination showed weakness and reduced temperature of all extremities, reduced pinprick and vibration sense of the distal extremities, loss of reflexes, and walking with a wide-based unsteady gait. Laboratory investigations showed positive antinuclear antibodies (ANA), anti-(smooth muscle (SM) antibody, anti-RNP antibody, anti-SSA antibody, anti-ds-DNA antibody, and an erythrocyte sedimentation rate (ESR) of 75 mm/hr, low C4, leukopenia, and anemia. Electromyography (EMG) confirmed the diagnosis of CIDP. The patient's neuropathy and muscle weakness improved on treatment with intravenous immunoglobulin (IVIG) and high-dose steroids. CONCLUSIONS The early clinical diagnosis of CIDP, supported by serological autoantibody profiles associated with SLE, can predict a good response to steroids. Most patients with CIDP are treated successfully with steroids if the diagnosis is made early. IVIG, plasmapheresis, or immunosuppressive therapy should be considered if there is no response to steroids.
    MeSH term(s) Adult ; Autoantibodies/blood ; Female ; Glucocorticoids/therapeutic use ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Lupus Erythematosus, Systemic/complications ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/diagnosis ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/drug therapy
    Chemical Substances Autoantibodies ; Glucocorticoids ; Immunoglobulins, Intravenous
    Language English
    Publishing date 2017-09-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/ajcr.903541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Sump Syndrome: A Rare Long-Term Complication of Choledochoduodenostomy

    Abraham, Hrudya / Thomas, Sajan / Srivastava, Amit

    Case Reports in Gastroenterology

    2017  Volume 11, Issue 2, Page(s) 428–433

    Abstract: Biliary sump syndrome is a rare condition. It is seen as a rare long-term complication in patients with a history of a side-to-side choledochoduodenostomy. In the era before endoscopic retrograde cholangiopancreatography, side-to-side ... ...

    Institution Internal Medicine Residency Program, MacNeal Hospital, Berwyn, Illinois, USA
    Transitional Year Residency Program, MacNeal Hospital, Berwyn, Illinois, USA
    Department of Internal Medicine, MacNeal Hospital, Berwyn, Illinois, USA
    Abstract Biliary sump syndrome is a rare condition. It is seen as a rare long-term complication in patients with a history of a side-to-side choledochoduodenostomy. In the era before endoscopic retrograde cholangiopancreatography, side-to-side choledochoduodenostomy was a common surgical procedure for the management of biliary obstruction. In the setting of a side-to-side choledochoduodenostomy, the bile does not drain through the distal common bile duct anymore. Therefore, the part of the common bile duct distal from the choledochoduodenostomy anastomosis consequently transforms into a poorly drained reservoir, making this so-called “sump” prone to accumulation of debris. These patients are prone to cholangitis. We present a 64-year-old man with a history of side-to-side choledochoduodenostomy who presented with manifestations of cholangitis. An endoscopic retrograde cholangiopancreatography confirmed a diagnosis of sump syndrome. The etiology, clinical manifestations, and treatment of biliary sump syndrome are discussed in this article.
    Keywords Sump syndrome ; Choledochoduodenostomy ; Complication
    Language English
    Publishing date 2017-08-04
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Single Case ; This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000477335
    Database Karger publisher's database

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  5. Article ; Online: Does Systemic Lupus Erythematosus Care Provided in a Lupus Clinic Result in Higher Quality of Care Than That Provided in a General Rheumatology Clinic?

    Arora, Shilpa / Nika, Ailda / Trupin, Laura / Abraham, Hrudya / Block, Joel / Sequeira, Winston / Yazdany, Jinoos / Jolly, Meenakshi

    Arthritis care & research

    2018  Volume 70, Issue 12, Page(s) 1771–1777

    Abstract: Objective: To compare the quality of care received by patients with systemic lupus erythematosus (SLE) in 2 settings within the academic institution (a dedicated lupus clinic and a general rheumatology clinic) using validated SLE quality measures.: ... ...

    Abstract Objective: To compare the quality of care received by patients with systemic lupus erythematosus (SLE) in 2 settings within the academic institution (a dedicated lupus clinic and a general rheumatology clinic) using validated SLE quality measures.
    Methods: One hundred fifty consenting, consecutive SLE patients receiving longitudinal care at the Rush University general rheumatology clinic (n = 73) or the subspecialty lupus clinic (n = 77) were recruited. An updated quality measure survey and retrospective medical chart review were used to evaluate each quality measure (n = 20). The overall and individual quality measure performance was calculated and compared between the 2 groups. Data on the number of SLE patients seen by each rheumatologist were collected to assess the relationship between SLE patient volume and quality measures.
    Results: Overall quality measure performance was significantly better in SLE patients receiving care at the lupus clinic (85.8% versus 70.2% of patients receiving care at the general rheumatology clinic; P = 0.001). Differences between the 2 groups were observed for sunscreen counseling (98.7% and 83.6%, respectively; P = 0.001), antiphospholipid antibody testing (71.4% and 37%, respectively; P < 0.001), pneumococcal vaccination (84.8% and 48.8%, respectively; P < 0.001), bone mineral density testing (94.2% and 54.5%, respectively; P < 0.001), drug counseling (92.2% and 80.8%, respectively; P = 0.04), use of a steroid-sparing agent (100% and 82%, respectively; P < 0.007), use of an angiotensin-converting enzyme inhibitor (94.4% and 58.3%, respectively; P = 0.03), and cardiovascular disease risk assessment (40.3% and 15.1%, respectively; P = 0.01). There was a moderate correlation between physician volume and quality measure performance (ρ = 0.48, P < 0.001).
    Conclusion: Compared with the general rheumatology clinic, the dedicated lupus clinic had better quality measure performance in this cross-sectional single-center study. In our health care system, we also observed indicators suggesting that rheumatologists with a higher volume of SLE patients provide higher quality of care.
    MeSH term(s) Adult ; Appointments and Schedules ; Chicago ; Cross-Sectional Studies ; Delivery of Health Care, Integrated/standards ; Female ; Humans ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/therapy ; Male ; Middle Aged ; Outcome and Process Assessment, Health Care/standards ; Outpatient Clinics, Hospital/standards ; Quality Indicators, Health Care/standards ; Retrospective Studies ; Rheumatologists/standards ; Rheumatology/standards ; Treatment Outcome ; Workload/standards
    Language English
    Publishing date 2018-11-10
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 645059-3
    ISSN 2151-4658 ; 0893-7524 ; 2151-464X
    ISSN (online) 2151-4658
    ISSN 0893-7524 ; 2151-464X
    DOI 10.1002/acr.23569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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