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  1. Book ; Online: Environmental pollution and chronic arsenicosis in South Calcutta / D. N. Guha Mazumder . [et al.]

    Guha Mazumder, D. N / Das Gupta, J / Chakraborty, A. K / Chatterjee, A / Das, D / Chakraborti, D

    1992  

    Keywords Arsenic ; Industrial waste ; Water pollutants ; Chemical ; India ; Environment and Public Health ; toxicity
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: Environmental pollution and chronic arsenicosis in South Calcutta / D. N. Guha Mazumder . [et al.]

    Guha Mazumder, D. N / Das Gupta, J / Chakraborty, A. K / Chatterjee, A / Das, D / Chakraborti, D

    1992  

    Keywords Arsenic ; Industrial waste ; Water pollutants ; Chemical ; India ; Environment and Public Health ; toxicity
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online: Chronic arsenic toxicity from drinking tubewell water in rural West Bengal / D. N. Guha Mazumder . [et al.]

    Guha Mazumder, D. N / Chakraborty, A. K / Ghose, A / Gupta, J. D / Chakraborty, D. P / Dey, S. B / Chattopadhyay, N

    1988  

    Keywords Water pollution ; Arsenic ; Liver diseases ; India ; Community Health and Primary Health Care ; toxicity ; chemically induced
    Document type Book ; Online
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  4. Book ; Online: Chronic arsenic toxicity from drinking tubewell water in rural West Bengal / D. N. Guha Mazumder . [et al.]

    Guha Mazumder, D. N / Chakraborty, A. K / Ghose, A / Gupta, J. D / Chakraborty, D. P / Dey, S. B / Chattopadhyay, N

    1988  

    Keywords Water pollution ; Arsenic ; Liver diseases ; India ; Community Health and Primary Health Care ; toxicity ; chemically induced
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Skin score correlates with global DNA methylation and GSTO1 A140D polymorphism in arsenic-affected population of Eastern India.

    Majumder, Moumita / Dasgupta, Uma B / Guha Mazumder, D N / Das, Nilansu

    Toxicology mechanisms and methods

    2017  Volume 27, Issue 6, Page(s) 467–475

    Abstract: Arsenic is a potent environmental toxicant causing serious public health concerns in India, Bangladesh and other parts of the world. Gene- and promoter-specific hypermethylation has been reported in different arsenic-exposed cell lines, whereas whole ... ...

    Abstract Arsenic is a potent environmental toxicant causing serious public health concerns in India, Bangladesh and other parts of the world. Gene- and promoter-specific hypermethylation has been reported in different arsenic-exposed cell lines, whereas whole genome DNA methylation study suggested genomic hypo- and hypermethylation after arsenic exposure in in vitro and in vivo studies. Along with other characteristic biomarkers, arsenic toxicity leads to typical skin lesions. The present study demonstrates significant correlation between severities of skin manifestations with their whole genome DNA methylation status as well as with a particular polymorphism (Ala 140 Asp) status in arsenic metabolizing enzyme Glutathione S-transferase Omega-1 (GSTO1) in arsenic-exposed population of the district of Nadia, West Bengal, India.
    Language English
    Publishing date 2017-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2081252-8
    ISSN 1537-6524 ; 1537-6516 ; 1051-7235
    ISSN (online) 1537-6524
    ISSN 1537-6516 ; 1051-7235
    DOI 10.1080/15376516.2017.1323255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3215: Show issues Location:
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  6. Article: Hepatology in Kolkata.

    Guha Mazumder, D N

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2007  Volume 26 Suppl 1, Page(s) S18–23

    MeSH term(s) Animals ; Gastroenterology/history ; Gastroenterology/trends ; History, 20th Century ; Humans ; India ; Liver Diseases/history
    Language English
    Publishing date 2007-07-17
    Publishing country India
    Document type Historical Article ; Journal Article
    ZDB-ID 632595-6
    ISSN 0254-8860
    ISSN 0254-8860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Chronic arsenic toxicity & human health.

    Guha Mazumder, D N

    The Indian journal of medical research

    2008  Volume 128, Issue 4, Page(s) 436–447

    Abstract: Chronic arsenic toxicity (arsenicosis) due to drinking of arsenic contaminated ground water is a major environmental health hazard throughout the world including India. A lot of new information is emerging from extensive research on health effects of ... ...

    Abstract Chronic arsenic toxicity (arsenicosis) due to drinking of arsenic contaminated ground water is a major environmental health hazard throughout the world including India. A lot of new information is emerging from extensive research on health effects of chronic arsenic toxicity (CAT) in humans during the last two decades. Available literature has been reviewed to highlight the problem including its malignancies. Pigmentation and keratosis are the specific skin lesions characteristics of CAT. CAT also produces various systemic manifestations over and above skin lesions, important ones being chronic lung disease like chronic bronchitis, chronic obstructive pulmonary disease and bronchiectasis, liver disease like non-cirrhotic portal fibrosis and other diseases like polyneuropathy, peripheral vascular disease, hypertension and ischeamic heart disease, diabetes mellitus, non-pitting oedema of feet/hands, weakness and anaemia. Cancer of skin, lung and urinary bladder are important cancers associated with chronic arsenic toxicity. Stoppage of drinking of arsenic contaminated water is the main stay in the management of arsenicosis as specific chelation therapy has limited value. Early skin cancer, detectable by regular active surveillance, is curable. In addition to dermatological features, CAT produces protean clinical manifestations. Treatment of arsenicosis is unsatisfactory and is mostly symtomatic.
    MeSH term(s) Arsenic/toxicity ; Environmental Exposure ; Humans ; Water Pollutants, Chemical/toxicity ; Water Supply
    Chemical Substances Water Pollutants, Chemical ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2008-10
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Arsenic and non-malignant lung disease.

    Guha Mazumder, D N

    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

    2007  Volume 42, Issue 12, Page(s) 1859–1867

    Abstract: Many aquifers in various parts of the world have been found to be contaminated with arsenic at concentration above 0.05 mg/L. However reports of large number of affected people in India and Bangladesh are unprecedented. Characteristic skin lesions ( ... ...

    Abstract Many aquifers in various parts of the world have been found to be contaminated with arsenic at concentration above 0.05 mg/L. However reports of large number of affected people in India and Bangladesh are unprecedented. Characteristic skin lesions (pigmentation, depigmentation and keratosis) are the hallmark signs of chronic arsenic toxicity. Emerging evidences show that ingestion of arsenic through drinking water may also lead to non-malignant respiratory effects. Early report of non-malignant pulmonary effect of chronic ingestion of arsenic was available from studies in children in Chile as early as 1970. However on the basis of case studies, respiratory effect of chronic arsenic toxicity in adults following drinking of arsenic contaminated water in West Bengal was first reported in 1997. Epidemiological studies carried out in West Bengal on a population of 7683 showed that the prevalence odds ratio (POR) estimates were markedly increased for participants with arsenic induced skin lesions who also had high levels of arsenic in their current drinking water source (> or = 0.5 mg/L) compared with individuals who had normal skin and were exposed to low levels of arsenic (< 0.05 mg/L). In participants with skin lesions, age-adjusted POR estimates for chronic cough were 7.8 for females (95% CI:3.1-19.5) and 5.0 for males (95% CI:2.6-9.9). In Bangladesh, similar study carried out on a population of 218 showed that the crude prevalence ratio for chronic bronchitis was found to be 10.3 (95% CI:2.4-43.1) for females and 1.6 (95% CI:0.8-3.1) for males. Reports of lung function tests were available from both hospital and population based studies. Results show evidences of restrictive, obstructive and combined obstructive and restrictive lung disease in different people having chronic lung disease associated with chronic arsenic toxicity. On the basis of clinical study, chest X-ray and HRCT done in Arsenicosis patients with features of chronic lung disease, the abnormalities observed were varied. Evidences of obstructive pulmonary disease (COPD), interstitial lung disease (ILD) and bronchiectasis were found in some of the cases. Results of studies carried out on people showing features of Arsenicosis due to drinking arsenic contaminated water provide evidence that arsenic is a potent respiratory toxicant, even following ingestion.
    MeSH term(s) Adult ; Arsenic/analysis ; Arsenic Poisoning/epidemiology ; Arsenic Poisoning/etiology ; Arsenic Poisoning/pathology ; Bangladesh/epidemiology ; Bronchiectasis/chemically induced ; Bronchiectasis/epidemiology ; Bronchiectasis/pathology ; Bronchitis, Chronic/chemically induced ; Bronchitis, Chronic/epidemiology ; Bronchitis, Chronic/pathology ; Environmental Exposure/adverse effects ; Environmental Exposure/analysis ; Female ; Humans ; India/epidemiology ; Lung Diseases/chemically induced ; Lung Diseases/epidemiology ; Lung Diseases/pathology ; Lung Diseases, Interstitial/chemically induced ; Lung Diseases, Interstitial/epidemiology ; Lung Diseases, Interstitial/pathology ; Male ; Middle Aged ; Odds Ratio ; Prevalence ; Pulmonary Disease, Chronic Obstructive/chemically induced ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Disease, Chronic Obstructive/pathology ; Skin Diseases/chemically induced ; Skin Diseases/epidemiology ; Skin Diseases/pathology ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/poisoning ; Water Supply/analysis
    Chemical Substances Water Pollutants, Chemical ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2007-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 196584-0
    ISSN 1532-4117 ; 1093-4529 ; 0360-1226 ; 1077-1204
    ISSN (online) 1532-4117
    ISSN 1093-4529 ; 0360-1226 ; 1077-1204
    DOI 10.1080/10934520701566926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1217: Show issues Location:
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  9. Article: Effect of drinking arsenic contaminated water in children.

    Mazumder, D N Guha

    Indian pediatrics

    2007  Volume 44, Issue 12, Page(s) 925–927

    Abstract: Objective: Chronic arsenic toxicity due to drinking of arsenic contaminated water is a major environmental health hazard throughout the world including India. Though lot of information is available on health effects due to chronic arsenic toxicity in ... ...

    Abstract Objective: Chronic arsenic toxicity due to drinking of arsenic contaminated water is a major environmental health hazard throughout the world including India. Though lot of information is available on health effects due to chronic arsenic toxicity in adults, knowledge of such effect on children is scanty. A review of available literature has been made to highlight the problem in children.
    Review methods: Scientific publication in journals, monograph, thesis and proceedings of conferences on arsenic in regard to epidemiological, clinical and psychometric studies were reviewed.
    Results: Skin abnormalities including pigmentation change and keratosis are the diagnostic signs of chronic arsenic toxicity in adults. Incidence of skin manifestations vary between 1.9-37.1% in various arsenic exposed children populations in different regions of the world. Occurrence of chronic lung disease including pulmonary interstitial fibrosis was described in arsenic exposed children in Chile. Affection of intellectual function is also reported from Thailand, Bangladesh and India.
    Conclusion: Chronic arsenic toxicity due to drinking of arsenic contaminated water causes significant morbidity in children in different parts of the world.
    MeSH term(s) Adolescent ; Arsenic Poisoning/complications ; Arsenic Poisoning/epidemiology ; Child ; Child Welfare ; Child, Preschool ; Chronic Disease ; Environmental Exposure/adverse effects ; Female ; Humans ; India/epidemiology ; Infant ; Infant, Newborn ; Keratosis/chemically induced ; Keratosis/epidemiology ; Male ; Risk Factors ; Skin ; Skin Diseases/chemically induced ; Skin Diseases/epidemiology ; Water Pollutants, Chemical/toxicity ; Water Pollution, Chemical/adverse effects
    Chemical Substances Water Pollutants, Chemical
    Language English
    Publishing date 2007-12
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 402594-5
    ISSN 0019-6061
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Arsenic exposure and health effects.

    Guha Mazumder, D N

    Journal of toxicology. Clinical toxicology

    2002  Volume 40, Issue 4, Page(s) 527–8; author reply 529–30

    MeSH term(s) Arsenic Poisoning/complications ; Humans ; Laryngitis/chemically induced ; Muscular Diseases/chemically induced
    Language English
    Publishing date 2002
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 204476-6
    ISSN 1556-9519 ; 0731-3810 ; 0009-9309 ; 1556-3650
    ISSN (online) 1556-9519
    ISSN 0731-3810 ; 0009-9309 ; 1556-3650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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