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  1. Book ; Online ; E-Book: Orphan lung diseases

    Cottin, Vincent / Richeldi, Luca / Brown, Kevin / McCormack, Francis X.

    a clinical guide to rare lung disease

    2023  

    Author's details Vincent Cottin, Luca Richeldi, Kevin Brown, Francis X. McCormack editors
    Keywords Internal medicine ; Lung Diseases / physiopathology ; Rare Diseases / physiopathology
    Language English
    Size 1 Online-Ressource (xiii, 806 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030016162
    ISBN 978-3-031-12950-6 ; 9783031129490 ; 3-031-12950-4 ; 3031129490
    DOI 10.1007/978-3-031-12950-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Interstitial lung disease and autoimmune lung diseases

    Brown, Kevin K.

    (Immunology and allergy clinics of North America ; 32,4)

    2012  

    Author's details ed. Kevin K. Brown
    Series title Immunology and allergy clinics of North America ; 32,4
    Collection
    Language English
    Size XIV S., S. 454 - 684 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT017503930
    ISBN 978-1-4557-4846-4 ; 1-4557-4846-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 710 -32,4- verfügbar in Königswinter Königswinter

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  3. Book: Oxford American handbook of pulmonary medicine

    Brown, Kevin

    (Oxford American handbooks)

    2009  

    Title variant Handbook of pulmonary medicine ; American handbook of pulmonary medicine
    Author's details Kevin K. Brown
    Series title Oxford American handbooks
    Keywords Respiratory Tract Diseases / diagnosis ; Respiratory Tract Diseases / therapy
    Language English
    Size XLIV, 848 S. : Ill.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT016251110
    ISBN 978-0-19-532956-8 ; 0-19-532956-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 947 order for loan Magazin

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  4. Article ; Online: Interstitial Lung Disease: 150 Years of Progress.

    Solomon, Joshua J / Brown, Kevin K

    Immunology and allergy clinics of North America

    2023  Volume 43, Issue 2, Page(s) xiii–xv

    MeSH term(s) Humans ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/epidemiology ; Lung Diseases, Interstitial/therapy ; Disease Progression ; Lung
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2023.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 710: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Cooperative Pd/Cu Catalysis for Alkene Arylboration: Opportunities for Divergent Reactivity.

    Dorn, Stanna K / Brown, M Kevin

    ACS catalysis

    2022  Volume 12, Issue 3, Page(s) 2058–2063

    Abstract: A preeminent challenge in alkene difunctionalization is the control of regio-, diastereo-, and enantioselectivity. In this Perspective, a Pd/Cu-cooperative catalytic system for alkene arylboration is highlighted that allows for the controlled ... ...

    Abstract A preeminent challenge in alkene difunctionalization is the control of regio-, diastereo-, and enantioselectivity. In this Perspective, a Pd/Cu-cooperative catalytic system for alkene arylboration is highlighted that allows for the controlled introduction of substituents. In particular, examples that allowed for divergent reactivity from a single substrate based on the tuning of catalysts and reaction conditions are emphasized.
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Journal Article
    ISSN 2155-5435
    ISSN 2155-5435
    DOI 10.1021/acscatal.1c05696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Progressive Pulmonary Fibrosis: Should the Timelines Be Taken Out of the Definition?

    Cottin, Vincent / Brown, Kevin K / Flaherty, Kevin R / Wells, Athol U

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 10, Page(s) 1293–1294

    MeSH term(s) Humans ; Idiopathic Pulmonary Fibrosis/diagnosis
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202206-1143LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article: pH jump kinetics in colliding microdroplets: accelerated synthesis of azamonardine from dopamine and resorcinol.

    Brown, Emily K / Rovelli, Grazia / Wilson, Kevin R

    Chemical science

    2023  Volume 14, Issue 23, Page(s) 6430–6442

    Abstract: Recent studies report the dramatic acceleration of chemical reactions in micron-sized compartments. In the majority of these studies the exact acceleration mechanism is unknown but the droplet interface is thought to play a significant role. Dopamine ... ...

    Abstract Recent studies report the dramatic acceleration of chemical reactions in micron-sized compartments. In the majority of these studies the exact acceleration mechanism is unknown but the droplet interface is thought to play a significant role. Dopamine reacts with resorcinol to form a fluorescent product azamonardine and is used as a model system to examine how droplet interfaces accelerate reaction kinetics. The reaction is initiated by colliding two droplets levitated in a branched quadrupole trap, which allows the reaction to be observed in individual droplets where the size, concentration, and charge are carefully controlled. The collision of two droplets produces a pH jump and the reaction kinetics are quantified optically and
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc01576a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Myositis-associated interstitial lung disease.

    Vu, Trang T T / Brown, Kevin K / Solomon, Joshua J

    Current opinion in pulmonary medicine

    2023  Volume 29, Issue 5, Page(s) 427–435

    Abstract: Purpose of review: In idiopathic inflammatory myopathies (IIMs), interstitial lung disease (ILD) is common and the autoantibody profile, made up of myositis-specific and myositis-associated (MSA and MAA) antibodies, can predict the clinical phenotype ... ...

    Abstract Purpose of review: In idiopathic inflammatory myopathies (IIMs), interstitial lung disease (ILD) is common and the autoantibody profile, made up of myositis-specific and myositis-associated (MSA and MAA) antibodies, can predict the clinical phenotype and progression over time. This review will focus on the characteristics and management of antisynthetase syndrome related ILD and anti-MDA5 positive ILD, which are the most clinically relevant subtypes.
    Recent findings: The prevalence of ILD in IIM has been estimated in Asia, North America and Europe at 50, 23 and 26%, respectively, and is increasing. In antisynthetase syndrome related ILD, the clinical presentation, progression and prognosis varies among anti-ARS antibodies. ILD is more common and severe in patients with anti-PL-7/anti-PL-12 antibodies when compared with anti Jo-1 patients. The prevalence of anti-MDA5 antibodies is higher in Asians (11-60%) than in whites (7-16%). Sixty-six percent of antisynthetase syndrome patients had 'chronic ILD' compared with the more rapidly progressive ILD (RP-ILD) seen in 69% of patients with anti-MDA5 antibodies.
    Summary: ILD is most common in the antisynthetase subtype of IIM and can be a chronic indolent or RP- ILD. The MSA and MAAs are associated with different clinical phenotypes of ILD. Treatments typically involve combinations of corticosteroids and other immunosuppressants.
    MeSH term(s) Humans ; Myositis/complications ; Myositis/drug therapy ; Autoantibodies ; Lung Diseases, Interstitial/etiology ; Lung Diseases, Interstitial/complications ; Immunosuppressive Agents
    Chemical Substances Autoantibodies ; Immunosuppressive Agents
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000001000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4900: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Poxed and scurvied

    Brown, Kevin

    the story of sickness and health at sea

    2011  

    Title variant Poxed & scurvied
    Author's details Kevin Brown
    Language English
    Size IX, 246 S., [4] Bl. : Ill.
    Publisher Seaforth Publ
    Publishing place Barnsley
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT016877613
    ISBN 978-1-84832-063-5 ; 1-84832-063-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 2807 order for loan Magazin

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  10. Article ; Online: Nintedanib in Progressive Fibrosing Interstitial Lung Diseases. Reply.

    Flaherty, Kevin R / Wells, Athol U / Brown, Kevin K

    The New England journal of medicine

    2020  Volume 382, Issue 8, Page(s) 781

    MeSH term(s) Humans ; Indoles ; Lung Diseases, Interstitial ; Pulmonary Fibrosis
    Chemical Substances Indoles ; nintedanib (G6HRD2P839)
    Language English
    Publishing date 2020-02-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1917224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.34: Show issues Location:
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