LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 569

Search options

  1. Article ; Online: Fevipiprant, a selective prostaglandin D

    Hardman, Clare / Chen, Wentao / Luo, Jian / Batty, Paul / Chen, Yi-Ling / Nahler, Janina / Wu, Yanqiu / Pavord, Ian D / Erpenbeck, Veit J / Sandham, David A / Xue, Luzheng / Ogg, Graham

    The Journal of allergy and clinical immunology

    2019  Volume 143, Issue 6, Page(s) 2329–2333

    MeSH term(s) Cell Aggregation/drug effects ; Cytokines/genetics ; Cytokines/metabolism ; Humans ; Immunity, Innate/drug effects ; Indoleacetic Acids/pharmacology ; Lymphocytes/drug effects ; Lymphocytes/physiology ; Pyridines/pharmacology ; Receptors, Immunologic/antagonists & inhibitors ; Receptors, Prostaglandin/antagonists & inhibitors
    Chemical Substances Cytokines ; Indoleacetic Acids ; Pyridines ; Receptors, Immunologic ; Receptors, Prostaglandin ; fevipiprant (2PEX5N7DQ4) ; prostaglandin D2 receptor (XZF106QU24)
    Language English
    Publishing date 2019-02-28
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2019.02.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.92: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Online ; E-Book: The asthmas

    Backer, Vibeke / Gibson, Peter G. / Pavord, Ian D.

    a precision medicine approach to treatable traits, diagnosis and management

    2023  

    Author's details Vibeke Backer, Peter G. Gibson, Ian D. Pavord
    Keywords Asthma ; Lungs/Diseases
    Subject code 616.2/38
    Language English
    Size 1 Online-Ressource (142 Seiten)
    Publisher CRC Press
    Publishing place Boca Raton, Florida
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-429-33029-4 ; 1-000-63880-4 ; 0-367-35273-7 ; 978-0-429-33029-2 ; 978-1-000-63880-6 ; 978-0-367-35273-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D

    Chen, Wentao / Luo, Jian / Ye, Yuan / Hoyle, Ryan / Liu, Wei / Borst, Rowie / Kazani, Shamsah / Shikatani, Eric A / Erpenbeck, Veit J / Pavord, Ian D / Klenerman, Paul / Sandham, David A / Xue, Luzheng

    Journal of immunology (Baltimore, Md. : 1950)

    2021  Volume 206, Issue 11, Page(s) 2714–2724

    Abstract: Human type 2 cytotoxic T (Tc2) cells are enriched in severe eosinophilic asthma and can contribute to airway eosinophilia. ... ...

    Abstract Human type 2 cytotoxic T (Tc2) cells are enriched in severe eosinophilic asthma and can contribute to airway eosinophilia. PGD
    MeSH term(s) Cells, Cultured ; Coculture Techniques ; Humans ; Indoleacetic Acids/pharmacology ; Inflammation/drug therapy ; Inflammation/immunology ; Prostaglandin D2/antagonists & inhibitors ; Prostaglandin D2/biosynthesis ; Pyridines/pharmacology ; Receptors, Immunologic/antagonists & inhibitors ; Receptors, Immunologic/immunology ; Receptors, Prostaglandin/antagonists & inhibitors ; Receptors, Prostaglandin/immunology ; T-Lymphocytes, Cytotoxic/drug effects ; T-Lymphocytes, Cytotoxic/immunology
    Chemical Substances Indoleacetic Acids ; Pyridines ; Receptors, Immunologic ; Receptors, Prostaglandin ; fevipiprant (2PEX5N7DQ4) ; Prostaglandin D2 (RXY07S6CZ2) ; prostaglandin D2 receptor (XZF106QU24)
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.2001245
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.37: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 28: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Case-finding and diagnosis of obstructive airway diseases: the Dragons' Den experience.

    Pavord, Ian D

    The European respiratory journal

    2022  Volume 60, Issue 3

    MeSH term(s) Asthma/diagnosis ; Humans ; Machine Learning ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-09-22
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00679-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2322: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Challenges and Opportunities in Asthma Prevention and Treatment.

    Gern, James E / Pavord, Ian D

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 3, Page(s) 748–749

    MeSH term(s) Humans ; Asthma/epidemiology ; Asthma/prevention & control
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2022.12.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Which biologic? New findings from a real-world study.

    Lavoie, Gabriel / Pavord, Ian D

    Respirology (Carlton, Vic.)

    2023  Volume 28, Issue 12, Page(s) 1091–1092

    MeSH term(s) Humans ; Biological Products/therapeutic use
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-09-21
    Publishing country Australia
    Document type Editorial
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14606
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4957: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Type 2 inflammation and biological therapies in asthma: Targeted medicine taking flight.

    Howell, Imran / Howell, Aleksandra / Pavord, Ian D

    The Journal of experimental medicine

    2023  Volume 220, Issue 7

    Abstract: The field of asthma has undergone a dramatic change in recent years. Advances in our understanding of type 2 airway inflammation have driven the discovery of monoclonal antibodies targeting specific aspects of the immune pathway. In landmark trials, ... ...

    Abstract The field of asthma has undergone a dramatic change in recent years. Advances in our understanding of type 2 airway inflammation have driven the discovery of monoclonal antibodies targeting specific aspects of the immune pathway. In landmark trials, these drugs have shown efficacy in reducing asthma attacks and exposure to oral corticosteroids, important causes of morbidity in people with asthma. Our review explores the key features of type 2 inflammation in asthma and summarizes the clinical trial evidence of the novel monoclonal antibody treatments and future avenues for treatment.
    MeSH term(s) Humans ; Asthma ; Antibodies, Monoclonal/therapeutic use ; Inflammation/complications ; Biological Therapy/adverse effects
    Chemical Substances Antibodies, Monoclonal
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218343-2
    ISSN 1540-9538 ; 0022-1007
    ISSN (online) 1540-9538
    ISSN 0022-1007
    DOI 10.1084/jem.20221212
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.107: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 45: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Living without eosinophils: evidence from mouse and man.

    Jackson, David J / Pavord, Ian D

    The European respiratory journal

    2023  Volume 61, Issue 1

    Abstract: The enduring view of eosinophils, as immune effector cells whose primary function is host defence against infection by helminths and other microbial pathogens, sets the stage for a fundamental question regarding the safety of therapeutic eosinophil ... ...

    Abstract The enduring view of eosinophils, as immune effector cells whose primary function is host defence against infection by helminths and other microbial pathogens, sets the stage for a fundamental question regarding the safety of therapeutic eosinophil depletion. If eosinophils are significantly reduced or altogether depleted in an effort to alleviate the negative effects of tissue eosinophilia and eosinophilic inflammation in conditions such as asthma, COPD, chronic rhinosinusitis with nasal polyps, eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome, would these patients become susceptible to infection or another illness? Development of mouse models in which the eosinophil lineage has been ablated, observations in patients naturally lacking eosinophils and data from studies of eosinophil-depleting medical therapies indicate that the absence of eosinophils is not detrimental to health. The evidence available to date, as presented in this review, supports the conclusion that even if certain homeostatic roles for the eosinophil may be demonstrable in controlled animal models and human
    MeSH term(s) Animals ; Humans ; Eosinophils ; Rhinitis ; Churg-Strauss Syndrome ; Granulomatosis with Polyangiitis ; Eosinophilia ; Nasal Polyps
    Language English
    Publishing date 2023-01-12
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01217-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2322: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Type-2 inflammation: a key treatable trait associated with lung function decline in chronic airways disease.

    Petousi, Nayia / Pavord, Ian D / Kent, Brian Daniel

    Thorax

    2024  Volume 79, Issue 4, Page(s) 291–292

    MeSH term(s) Humans ; Pulmonary Disease, Chronic Obstructive ; Asthma ; Inflammation ; Lung
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Editorial
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thorax-2023-221329
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.83: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Blood Eosinophil-directed Management of Airway Disease. The Past, Present, and Future.

    Pavord, Ian D

    American journal of respiratory and critical care medicine

    2020  Volume 202, Issue 5, Page(s) 637–639

    MeSH term(s) Asthma/drug therapy ; Eosinophils ; Humans ; Pulmonary Disease, Chronic Obstructive ; Respiration Disorders
    Keywords covid19
    Language English
    Publishing date 2020-04-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202004-1013ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top