Article ; Online: The value of periodic spirometry for early recognition of long-term excessive lung function decline in individuals.
Journal of occupational and environmental medicine
2012 Volume 54, Issue 12, Page(s) 1506–1512
Abstract: Objective: To establish the value of workplace spirometry monitoring methods for early recognition of long-term excessive lung function decline in individuals.: Methods: Sensitivity, specificity, and positive likelihood ratio were calculated to ... ...
Abstract | Objective: To establish the value of workplace spirometry monitoring methods for early recognition of long-term excessive lung function decline in individuals. Methods: Sensitivity, specificity, and positive likelihood ratio were calculated to determine the predictive value of the linear regression slope and limits of longitudinal decline for early prediction of long-term excessive forced expiratory volume in 1 second (FEV1) decline (> 90 mL/yr established over 9 to 11 years) in ongoing spirometry monitoring programs (firefighters and construction workers) and a historical program (paper-pulp mill workers). The longitudinal limits account for the expected FEV1 within-person variability. Results: The longitudinal limits achieved clinical "usefulness" (positive likelihood ratio 10 or higher) from the fourth to fifth year of follow-up, whereas the linear regression slope was less useful. The usefulness depended on data precision and measurement frequency. Conclusion: The limits of longitudinal decline are more useful for early recognition of long-term excessive FEV1 decline than the linear regression slope. |
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MeSH term(s) | Adult ; Construction Industry ; Disease Progression ; Firefighters ; Follow-Up Studies ; Forced Expiratory Volume ; Humans ; Linear Models ; Male ; Middle Aged ; Occupational Diseases/diagnosis ; Occupational Diseases/physiopathology ; Occupational Health Services/methods ; Predictive Value of Tests ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Sensitivity and Specificity ; Spirometry |
Language | English |
Publishing date | 2012-12 |
Publishing country | United States |
Document type | Evaluation Studies ; Journal Article ; Research Support, N.I.H., Intramural |
ZDB-ID | 1223932-x |
ISSN | 1536-5948 ; 1076-2752 |
ISSN (online) | 1536-5948 |
ISSN | 1076-2752 |
DOI | 10.1097/JOM.0b013e3182664811 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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