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  1. Article ; Online: A comparison of artificial intelligence versus radiologists in the diagnosis of thyroid nodules using ultrasonography: a systematic review and meta-analysis.

    Potipimpanon, Pimrada / Charakorn, Natamon / Hirunwiwatkul, Prakobkiat

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  Volume 279, Issue 11, Page(s) 5363–5373

    Abstract: Background: Thyroid nodules are common. Ultrasonography (US) is the first investigation for thyroid nodules. Artificial Intelligence (AI) is widely integrated into medical diagnosis to provide additional information. The primary objective of this study ... ...

    Abstract Background: Thyroid nodules are common. Ultrasonography (US) is the first investigation for thyroid nodules. Artificial Intelligence (AI) is widely integrated into medical diagnosis to provide additional information. The primary objective of this study was to accumulate the pooled sensitivity and specificity between all available AI and radiologists using thyroid US imaging. The secondary objective was to compare AI's diagnostic performance to that of radiologists.
    Materials and methods: A systematic review meta-analysis. PubMed, Scopus, Web of Science, and Cochrane Library data were searched for studies from inception until June 11, 2020.
    Results: Twenty five studies were included in this meta-analysis. The pooled sensitivity and specificity of AI were 0.86 (95% CI 0.81-0.91) and 0.78 (95% CI 0.73-0.83), respectively. The pooled sensitivity and specificity of radiologists were 0.85 (95% CI 0.80-0.89) and 0.82 (95% CI 0.77-0.86), respectively. The accuracy of AI and radiologists is equivalent in terms of AUC [AI 0.89 (95% CI 0.86-0.92), radiologist 0.91 (95% CI 0.88-0.93)]. The diagnostic odd ratio (DOR) between AI 23.10 (95% CI 14.20-37.58) and radiologists 27.12 (95% CI 17.45-42.16) had no statistically significant difference (P = 0.56). Meta-regression analysis revealed that Deep Learning AI had significantly greater sensitivity and specificity than classic machine learning AI (P < 0.001).
    Conclusion: AI demonstrated comparable performance to radiologists in diagnosing benign and malignant thyroid nodules using ultrasonography. Additional research to establish its equivalency should be conducted.
    MeSH term(s) Artificial Intelligence ; Humans ; Radiologists ; Sensitivity and Specificity ; Thyroid Nodule/diagnostic imaging ; Thyroid Nodule/pathology ; Ultrasonography/methods
    Language English
    Publishing date 2022-06-29
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07436-1
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  2. Article: The use of topical nasal steroids to improve continuous positive airway pressure compliance in patients with obstructive sleep apnea: An updated systematic review and meta-analysis of randomized control trials.

    Segsarnviriya, Charnsiri / Prakassajjatham, Mantana / Chirakalwasan, Naricha / Hirunwiwatkul, Prakobkiat / Chaitusaney, Busarakum / Charakorn, Natamon

    Asian Pacific journal of allergy and immunology

    2023  

    Abstract: Background: Nasal steroids are commonly prescribed to reduce nasal side effects, which are the primary cause of continuous positive airway pressure (CPAP) intolerance in obstructive sleep apnea (OSA) patients.: Objective: We conducted a systematic ... ...

    Abstract Background: Nasal steroids are commonly prescribed to reduce nasal side effects, which are the primary cause of continuous positive airway pressure (CPAP) intolerance in obstructive sleep apnea (OSA) patients.
    Objective: We conducted a systematic review and meta-analysis of OSA patients to assess the effect of nasal steroids on CPAP compliance and nasal symptoms.
    Methods: PubMed, Scopus, Ovid, and Cochrane Library were searched through March 2022. Randomized controlled trials (RCTs) evaluating the effects of nasal steroids on CPAP compliance in adult patients, which reported quantitative data on CPAP use and nasal symptoms, were included.
    Results: Three RCTs (224 patients) were eligible for the meta-analysis. At the 4-week follow-up, the study did not demonstrate a statistically significant difference in CPAP compliance (average hours of CPAP use per night: mean difference 0.45; 95% confident interval (CI) (-0.01, 0.90); P = 0.06, percentage of nights device used: mean difference 1.79; 95%CI (-2.59, 6.17); P = 0.42). There was also no difference in overall nasal symptoms (mean difference 0.47, 95%CI (-0.00, 0.94); P = 0.05), with significantly more sneezing and rhinorrhea among patients with nasal steroids (sneezing: mean difference 0.64, 95%CI (0.23, 1.05); P = 0.002, rhinorrhea: mean difference 0.78, 95%CI (0.24, 1.31); P = 0.005).
    Conclusions: At the 4-week follow-up, the pooled results did not demonstrate significant benefits of nasal steroids on CPAP compliance. There was also no significant benefit for relieving nasal symptoms. To further explore the benefit of nasal steroids on CPAP use, additional, longer-term studies are required.
    Language English
    Publishing date 2023-04-17
    Publishing country Thailand
    Document type Journal Article
    ZDB-ID 605782-2
    ISSN 2228-8694 ; 0125-877X
    ISSN (online) 2228-8694
    ISSN 0125-877X
    DOI 10.12932/AP-081122-1498
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  3. Article ; Online: Adenotonsillectomy in children with syndromic craniosynostosis: a systematic review and meta-analysis.

    Saengthong, Petcharat / Chaitusaney, Busarakum / Hirunwiwatkul, Prakobkiat / Charakorn, Natamon

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2019  Volume 276, Issue 6, Page(s) 1555–1560

    Abstract: Objective: To conduct a systematic review and meta-analysis in children with syndromic craniosynostosis, to evaluate the effect of adenotonsillectomy for the treatment of obstructive sleep apnea (OSA).: Study design: A systematic review and meta- ... ...

    Abstract Objective: To conduct a systematic review and meta-analysis in children with syndromic craniosynostosis, to evaluate the effect of adenotonsillectomy for the treatment of obstructive sleep apnea (OSA).
    Study design: A systematic review and meta-analysis.
    Search methods: Data sources: a comprehensive search of PubMed, SCOPUS, Ovid Medline, and Web of science databases was performed through June 22nd, 2018. Manual searches and subject matter expert input were also obtained. This article includes studies assessing the effectiveness of adenotonsillectomy in syndromic craniosynostosis children, in which apnea-hypopnea index (AHI) or oxygen desaturation index (ODI) was reported.
    Results: A total of 3 retrospective studies (24 patients) met the inclusion criteria. Pooled random effect analysis did not identify a statistically significant difference between preoperative and postoperative AHI. But there was an overall reduction of AHI of 5.00 events per hour [95% confidence interval (CI) (- 17.79, 7.79); P = 0.44]. However, the fixed effect model demonstrated a statistically significant difference between preoperative and postoperative ODI with an overall reduction of 8.5 per hour [95% CI (- 15.01, - 1.99); P = 0.01].
    Conclusion: Adenotonsillectomy showed benefits for the treatment of OSA in syndromic craniosynostosis children, in terms of AHI and ODI. However, only ODI, but not AHI, reached statistical significance. Data were based on meta-analysis of retrospective reviews. Further studies that are conducted at multiple centers are needed to confirm the benefits of adenotonsillectomy for the treatment of OSA in syndromic craniosynostosis children.
    MeSH term(s) Adenoidectomy ; Child ; Craniosynostoses/complications ; Humans ; Models, Statistical ; Sleep Apnea, Obstructive/etiology ; Sleep Apnea, Obstructive/surgery ; Syndrome ; Tonsillectomy ; Treatment Outcome
    Language English
    Publishing date 2019-04-17
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-019-05427-3
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  4. Article ; Online: Drug-Induced Sleep Endoscopy.

    Charakorn, Natamon / Kezirian, Eric J

    Otolaryngologic clinics of North America

    2016  Volume 49, Issue 6, Page(s) 1359–1372

    Abstract: Drug-induced sleep endoscopy (DISE) is an upper airway evaluation technique in which fiberoptic examination is performed under conditions of unconscious sedation. Unique information obtained from this 3-dimensional examination of the airway potentially ... ...

    Abstract Drug-induced sleep endoscopy (DISE) is an upper airway evaluation technique in which fiberoptic examination is performed under conditions of unconscious sedation. Unique information obtained from this 3-dimensional examination of the airway potentially provides additive benefits to other evaluation methods to guide treatment selection. This article presents recommendations regarding DISE technique and the VOTE Classification system for reporting DISE findings and reviews the evidence concerning DISE test characteristics and the association between DISE findings and treatment outcomes.
    MeSH term(s) Electric Stimulation Therapy ; Endoscopy/methods ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypoglossal Nerve ; Monitoring, Physiologic ; Orthodontic Appliances, Removable ; Posture ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/therapy ; Stomatognathic System/anatomy & histology
    Chemical Substances Hypnotics and Sedatives
    Language English
    Publishing date 2016-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 417489-6
    ISSN 1557-8259 ; 0030-6665
    ISSN (online) 1557-8259
    ISSN 0030-6665
    DOI 10.1016/j.otc.2016.06.002
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  5. Article: Chronic sphenoid rhinosinusitis: management challenge.

    Charakorn, Natamon / Snidvongs, Kornkiat

    Journal of asthma and allergy

    2016  Volume 9, Page(s) 199–205

    Abstract: Chronic sphenoid rhinosinusitis is a spectrum of inflammatory diseases in isolated sphenoid sinus which may persist over a period of 12 weeks. It is a different entity from other types of rhinosinusitis because clinical presentations include headache, ... ...

    Abstract Chronic sphenoid rhinosinusitis is a spectrum of inflammatory diseases in isolated sphenoid sinus which may persist over a period of 12 weeks. It is a different entity from other types of rhinosinusitis because clinical presentations include headache, visual loss or diplopia, and patients may or may not have nasal obstruction or nasal discharge. Nasal endoscopic examination is useful, and computed tomography is mandatory. The disease requires comprehensive knowledge and appropriate imaging technique for diagnosis. To treat patients with chronic sphenoid rhinosinusitis, surgical treatment with endoscopic transnasal sphenoidotomy is often required. As there are no recent updated reviews of chronic sphenoid rhinosinusitis, in this article, we review the anatomy of the sphenoid sinus and its clinical relationship with the clinical signs and symptoms of the disease, the imaging findings of each diagnosis and the comprehensive surgical techniques.
    Language English
    Publishing date 2016-11-09
    Publishing country New Zealand
    Document type Review ; Journal Article
    ZDB-ID 2494877-9
    ISSN 1178-6965
    ISSN 1178-6965
    DOI 10.2147/JAA.S93023
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  6. Article ; Online: Lingual tonsillectomy with palatal surgery for the treatment of obstructive sleep apnea in adults: a systematic review and meta-analysis.

    Samutsakorn, Phantipar / Hirunwiwatkul, Prakobkiat / Chaitusaney, Busarakum / Charakorn, Natamon

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2018  Volume 275, Issue 4, Page(s) 1005–1013

    Abstract: Objective: To conduct a systematic review and meta-analysis to evaluate effects of lingual tonsillectomy with palatal surgery as a combined procedure for the treatment of obstructive sleep apnea (OSA) in adults.: Search methods: Data source: a ... ...

    Abstract Objective: To conduct a systematic review and meta-analysis to evaluate effects of lingual tonsillectomy with palatal surgery as a combined procedure for the treatment of obstructive sleep apnea (OSA) in adults.
    Search methods: Data source: a comprehensive search of MEDLINE, Scopus, Ovid, Web of Science, and the Cochrane Library was performed through November 2017. Manual searches and subject matter expert input were also obtained. This review includes studies assessing efficacy of lingual tonsillectomy with palatal surgery as a combined procedure for the treatment of OSA in adults, who had multilevel obstruction including lingual tonsil hypertrophy, in which apnea/hypopnea index (AHI) or respiratory disturbance index (RDI) were reported.
    Results: A total of four studies (107 patients) met our inclusion criteria. Pooled random effects analysis demonstrated a statistically significant improvement of polysomnographic respiratory events postoperatively, with average AHI reduction of 18.51 events per hour, [95% confidence interval (CI) (- 31.72, - 5.31); P = 0.006] and increase in minimal arterial oxygen saturation of 5.26 [95% CI (0.10, 10.42); P = 0.05]. The result also showed that the procedures significantly improved sleepiness resulting in an average Epworth Sleepiness Scale (ESS) reduction of 5.44 [95% CI (- 8.69, - 2.18); P = 0.001].
    Conclusion: A combination of lingual tonsillectomy with palatal surgery may offer benefits in a selected group of OSA adults, in terms of apnea/hypopnea index, minimal arterial oxygen saturation and Epworth Sleepiness Scale. Data were based on meta-analysis of all case series with 2-6 months' follow-up.
    MeSH term(s) Adult ; Humans ; Otorhinolaryngologic Surgical Procedures/methods ; Sleep Apnea, Obstructive/surgery ; Treatment Outcome
    Language English
    Publishing date 2018-04
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-018-4887-6
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  7. Article ; Online: The effects of a cold pack on postoperative turbinate and/or septal bleeding and pain.

    Hirunwiwatkul, Prakobkiat / Charakorn, Natamon / Teerapraipruk, Bussarakum / Jongsuebsit, Theerayoot

    American journal of rhinology & allergy

    2016  Volume 30, Issue 3, Page(s) 222–225

    Abstract: Background: The objective of this study is to evaluate the effects of a cold pack in postoperative turbinate and/or septal surgery in terms of postoperative bleeding control, pain management, and patient preference for or against application of a cold ... ...

    Abstract Background: The objective of this study is to evaluate the effects of a cold pack in postoperative turbinate and/or septal surgery in terms of postoperative bleeding control, pain management, and patient preference for or against application of a cold pack.
    Methods: A randomized controlled trial was done at the Department of Otolaryngology, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Ninety-nine adult subjects intending to have turbinate and/or septal surgery were consecutively enrolled in this study. Intervention was randomized into two groups. Postoperative bleeding was collected by paper tissue and weighed to determine amount and/or volume of blood loss. Postoperative pain was measured by using the visual analog scale. Patient preference for or against the use of a cold pack was also assessed.
    Results: The mean (standard deviation) postoperative bleeding in the cold pack group was 1.31 ± 1.50 g compared with 1.81 ± 1.89 g in the control group. The mean difference was 0.50 g (95% confidence interval, -0.19 to 1.19 g; p = 0.15). The mean (standard deviation) postoperative visual analog scale pain score in the cold pack group was 2.40 ± 2.32 compared with 3.33 ± 2.83 in the control group. The mean difference was 0.94 (95% confidence interval, -0.11 to 1.99; p = 0.79). Most of the subjects preferred using a cold pack (78.7%) to not using a cold pack (21.3%) (p < 0.001).
    Conclusion: A cold pack after turbinate and/or septal surgery had no benefit in terms of postoperative bleeding or postoperative pain.
    MeSH term(s) Adult ; Aged ; Cold Temperature ; Female ; Humans ; Male ; Middle Aged ; Nasal Septum/surgery ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Postoperative Hemorrhage/etiology ; Postoperative Hemorrhage/prevention & control ; Reconstructive Surgical Procedures ; Thailand ; Turbinates/surgery ; Visual Analog Scale ; Young Adult
    Language English
    Publishing date 2016-05
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.2500/ajra.2016.30.4306
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  8. Article ; Online: The effects of topical nasal steroids on continuous positive airway pressure compliance in patients with obstructive sleep apnea: a systematic review and meta-analysis.

    Charakorn, Natamon / Hirunwiwatkul, Prakobkiat / Chirakalwasan, Naricha / Chaitusaney, Busarakum / Prakassajjatham, Mantana

    Sleep & breathing = Schlaf & Atmung

    2017  Volume 21, Issue 1, Page(s) 3–8

    Abstract: Objectives: The purpose of the study was to conduct a systematic review and meta-analysis in patients with obstructive sleep apnea (OSA), evaluating effects of topical nasal steroids on continuous positive airway pressure (CPAP) machine use and nasal ... ...

    Abstract Objectives: The purpose of the study was to conduct a systematic review and meta-analysis in patients with obstructive sleep apnea (OSA), evaluating effects of topical nasal steroids on continuous positive airway pressure (CPAP) machine use and nasal symptoms.
    Search methods: Data source: A comprehensive search of Pubmed, Scopus, Web of Science, and the Cochrane Library was performed through April 2016. Manual searches and subject matter expert input were also obtained. Studies assessing effects of nasal steroids on CPAP machine use in adults, which reported quantitative outcome data of CPAP compliance, were included.
    Results: Two studies (144 patients) met inclusion criteria. Both were randomized, placebo-controlled clinical trials (RCT). Pooled fixed effects analysis did not identify a statistically significant difference between both the groups for average duration of CPAP machine use per night. But there was an overall increase in the usage of 0.4 h (95 % confidence interval (CI) (-0.20, 1.00); P = 0.19) in favor of nasal steroids. Difference of percentage of nights with CPAP use was not demonstrated (mean difference 0.06, 95 % CI (-0.27, 0.39); P = 0.71). There was also no significant difference in nasal symptoms (mean difference 0.63, 95 % CI (-0.11, 1.36), P = 0.1).
    Conclusion: Nasal steroids showed benefits on CPAP use, but did not reach statistical significance. Data was based on meta-analysis of RCTs of 4-week follow-up in unselected OSA patients. Future controlled studies with selected group and longer follow-up duration are needed to confirm the benefits of nasal steroid on CPAP compliance in OSA patients.
    Language English
    Publishing date 2017-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-016-1375-3
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  9. Article ; Online: Comparison of polysomnographic and clinical presentations and predictors for cardiovascular-related diseases between non-obese and obese obstructive sleep apnea among Asians.

    Chirakalwasan, Naricha / Teerapraipruk, Busarakum / Simon, Rosalind / Hirunwiwatkul, Prakobkiat / Jaimchariyatam, Nattapong / Desudchit, Tayard / Charakorn, Natamon / Wanlapakorn, Chaisiri

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2013  Volume 9, Issue 6, Page(s) 553–557

    Abstract: Introduction: Unlike Caucasians, many Asians with obstructive sleep apnea (OSA) are non-obese but are affected by the disease due to predisposing craniofacial structure. Therefore, non-obese and obese OSA may represent different disease entities. The ... ...

    Abstract Introduction: Unlike Caucasians, many Asians with obstructive sleep apnea (OSA) are non-obese but are affected by the disease due to predisposing craniofacial structure. Therefore, non-obese and obese OSA may represent different disease entities. The associated risk factors for developing cardiovascular-related diseases, consequently, may be considered separately for the two types of OSA.
    Method: We reviewed polysomnographic studies performed in adults (aged ≥ 18 years) diagnosed with OSA (respiratory disturbance index [RDI] ≥ 5). We divided the patients into obese (body mass index [BMI] ≥ 25) and non-obese (BMI < 25) groups. We aimed to determine the differences between these two groups in terms of clinical presentations, polysomno-graphic findings, and association with cardiovascular-related diseases including hypertension, diabetes mellitus, coronary artery disease, and/or cerebrovascular disease.
    Results: Among 194 patients with OSA (RDI ≥ 5), 63.4% were non-obese and 36.6% were obese. Compared with obese OSA patients, non-obese OSA patients were noted to have smaller neck size, less prevalence of hypertension, and less history of frequent nocturia (> 3-4/week), with equal prevalence of excessive daytime sleepiness. Overall, non-obese OSA patients were noted to have milder disease indicated by lower total, supine, and non-supine, NREM RDI and higher mean and nadir oxygen saturations. In the non-obese group, only total obstructive apnea index (OAI) was noted to be a predictor for developing any of the cardiovascular-related diseases after controlling for age, sex, and RDI (odds ratio = 9.7). However, in the obese OSA group, frequent snoring (> 50% of total sleep time), low sleep efficiency (≤ 90%), and low mean oxygen saturation (< 95%) were noted to be significant predictors of cardiovascular-related diseases (odds ratios = 12.3, 4.2, and 5.2, respectively).
    Conclusion: Among Asians, most OSA patients were not obese. Compared to obese OSA patients, non-obese OSA patients were noted to have less prevalence of hypertension and less history of nocturia. They were also noted to have overall milder OSA. Only OAI was noted to be a significant predictor for cardiovascular-related disease in the non-obese OSA group.
    MeSH term(s) Asian Continental Ancestry Group ; Cardiovascular Diseases/ethnology ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Obesity/ethnology ; Polysomnography ; Retrospective Studies ; Risk Factors ; Sleep Apnea, Obstructive/ethnology ; Thailand/epidemiology
    Language English
    Publishing date 2013-06-15
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.2748
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  10. Article: Severity of obstructive sleep apnea in patients with and without cardiovascular-related diseases.

    Simon, Rosalind / Chirakalwasan, Naricha / Teerapraipruk, Busarakum / Hirunwiwatkul, Prakobkiat / Jaimchariyatam, Nattapong / Desudchit, Tayard / Charakorn, Natamon / Wanlapakorn, Chaisiri

    Respiratory care

    2012  Volume 57, Issue 9, Page(s) 1476–1482

    Abstract: Background: Previous studies have often investigated the association of obstructive sleep apnea (OSA) with cardiovascular morbidity and mortality, but the possibility of reverse causation has not been clearly defined.: Objective: To examine if the ... ...

    Abstract Background: Previous studies have often investigated the association of obstructive sleep apnea (OSA) with cardiovascular morbidity and mortality, but the possibility of reverse causation has not been clearly defined.
    Objective: To examine if the presence of any of the cardiovascular-related diseases, including hypertension, diabetes mellitus, coronary artery disease, and/or cerebrovascular disease, correlates with more severe OSA.
    Methods: This was a retrospective study where all patients age ≥ 18 years referred to our sleep laboratory for suspected OSA were included. The data from the full-night baseline and split-night polysomnographic reports were reviewed. Data were then evaluated by logistic regression analysis to compare between 2 groups, the severity of OSA (respiratory disturbance index [RDI] < 15 vs RDI ≥ 15, and RDI < 5 vs RDI ≥ 5), other polysomnographic variables and daytime sleepiness score (Epworth Sleepiness Scale [ESS] score < 10 and ≥ 10).
    Results: 190 patients were analyzed. The patients with any of the cardiovascular-related diseases were noted to have more severe sleep apnea (RDI ≥ 15), with an adjusted odds ratio of 3.24. Sleep efficiency ≥ 90% and mean oxygen saturation ≥ 95% were observed less commonly in the patients with any of the cardiovascular-related diseases (adjusted odds ratios of 0.45 and 0.36, respectively). There was no statistically significant difference in ESS score.
    Conclusions: Patients with any of the cardiovascular-related diseases are at a higher risk of having moderate to severe OSA without significant increase in daytime sleepiness. Therefore, we suggest that patients with any of the cardiovascular-related diseases should be screened for OSA, even if they are asymptomatic.
    MeSH term(s) Adult ; Age Factors ; Aged ; Body Mass Index ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/physiopathology ; Disorders of Excessive Somnolence/complications ; Disorders of Excessive Somnolence/physiopathology ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Neck/anatomy & histology ; Odds Ratio ; Oximetry ; Polysomnography ; Retrospective Studies ; Severity of Illness Index ; Sleep/physiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/physiopathology
    Language English
    Publishing date 2012-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    DOI 10.4187/respcare.01660
    Database MEDical Literature Analysis and Retrieval System OnLINE

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