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  1. Book ; Online: Story, Michael McCarthy

    McCarthy, Michael

    2020  

    Abstract: Account of reflections inspired by Albert Camus' novel, The Plauge. ...

    Abstract Account of reflections inspired by Albert Camus' novel, The Plauge.
    Keywords Coronavirus infections--personal narratives ; COVID-19 (Disease)--Social aspects ; covid19
    Language English
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The professional legacy of Michael Metz.

    McCarthy, Barry

    Journal of sex & marital therapy

    2013  Volume 39, Issue 5, Page(s) 393

    MeSH term(s) Female ; History, 20th Century ; History, 21st Century ; Humans ; Male ; Marital Therapy/history ; Medical History Taking ; Professional Competence ; Professional Role/history ; Sexology/history ; Sexual Dysfunction, Physiological/history ; Sexual Dysfunction, Physiological/therapy ; Sexual Dysfunctions, Psychological/history ; Sexual Dysfunctions, Psychological/therapy ; United States
    Language English
    Publishing date 2013
    Publishing country England
    Document type Biography ; Historical Article ; Letter
    ZDB-ID 752393-2
    ISSN 1521-0715 ; 0092-623X
    ISSN (online) 1521-0715
    ISSN 0092-623X
    DOI 10.1080/0092623X.2013.796579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In memoriam: Michael John Welch, Ph.D 1939-2012.

    McCarthy, Timothy J / Vanbrocklin, Henry F

    Molecular imaging and biology

    2012  Volume 14, Issue 4, Page(s) 393–394

    MeSH term(s) Animals ; England ; History, 20th Century ; History, 21st Century ; Humans ; Molecular Imaging/history ; United States
    Language English
    Publishing date 2012-06-15
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 2079160-4
    ISSN 1860-2002 ; 1536-1632
    ISSN (online) 1860-2002
    ISSN 1536-1632
    DOI 10.1007/s11307-012-0570-2
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  4. Article ; Online: Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19.

    McCarthy, Michael J

    Brain, behavior, & immunity - health

    2022  Volume 20, Page(s) 100412

    Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a common and disabling disorder primarily characterized by persistent fatigue and exercise intolerance, with associated sleep disturbances, autonomic dysfunction, and cognitive problems. The ... ...

    Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a common and disabling disorder primarily characterized by persistent fatigue and exercise intolerance, with associated sleep disturbances, autonomic dysfunction, and cognitive problems. The causes of ME/CFS are not well understood but may coincide with immune and inflammatory responses following viral infections. During the current SARS-CoV2 coronavirus pandemic, ME/CFS has been increasingly reported to overlap with persistent "long COVID" symptoms, also called the post-acute sequelae of COVID-19 (PASC). Given the prominence of activity and sleep problems in ME/CFS, circadian rhythm disruption has been examined as a contributing factor in ME/CFS. While these studies of circadian rhythms have been pursued for decades, evidence linking circadian rhythms to ME/CFS remains inconclusive. A major limitation of older chronobiology studies of ME/CFS was the unavailability of modern molecular methods to study circadian rhythms and incomplete understanding of circadian rhythms outside the brain in peripheral organ systems. Major methodological and conceptual advancements in chronobiology have since been made. Over the same time, biomarker research in ME/CFS has progressed. Together, these new developments may justify renewed interest in circadian rhythm research in ME/CFS. Presently, we review ME/CFS from the perspective of circadian rhythms, covering both older and newer studies that make use of modern molecular methods. We focus on transforming growth factor beta (TGFB), a cytokine that has been previously associated with ME/CFS and has an important role in circadian rhythms, especially in peripheral cells. We propose that disrupted TGFB signaling in ME/CFS may play a role in disrupting physiological rhythms in sleep, activity, and cognition, leading to the insomnia, energy disturbances, cognition problems, depression, and autonomic dysfunction associated with ME/CFS. Since SARS-like coronavirus infections cause persistent changes in TGFB and previous coronavirus outbreaks have caused ME/CFS-like syndromes, chronobiological considerations may have immediate implications for understanding ME/CFS in the context of the COVID-19 pandemic and possibly suggest new avenues for therapeutic interventions.
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3546
    ISSN (online) 2666-3546
    DOI 10.1016/j.bbih.2022.100412
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  5. Article ; Online: The emerging landscape of eukaryotic polyphosphatases.

    McCarthy, Liam / Downey, Michael

    FEBS letters

    2023  Volume 597, Issue 11, Page(s) 1447–1461

    Abstract: Polyphosphate (polyP) is a conserved polymer of inorganic phosphate residues that can reach thousands of moieties in length. PolyP has been implicated in cellular functions ranging from energy and phosphate homeostasis to cell signalling in eukaryotes ... ...

    Abstract Polyphosphate (polyP) is a conserved polymer of inorganic phosphate residues that can reach thousands of moieties in length. PolyP has been implicated in cellular functions ranging from energy and phosphate homeostasis to cell signalling in eukaryotes from yeast to humans. Despite the interest in the role of polyP as a signalling molecule, the spatiotemporal regulation of polyP itself remains poorly understood. This knowledge gap limits our ability to understand how polyP impacts the physiology of normal and diseased cells and how this might be exploited in a therapeutic context. Polyphosphatases, enzymes that degrade polyP to generate shorter chains and free inorganic phosphate are ideally positioned to mediate polyP dynamics. However, little is known about how the activities of these enzymes are linked to specific cellular functions and how they might be regulated. Here, we provide an in-depth overview of polyphosphatase enzymes in budding yeast, which has served as a workhorse for polyP research, and in mammalian cells where the enzymes that make and degrade polyP have remained elusive. We identify critical open questions in both systems and propose strategies to guide future work.
    MeSH term(s) Animals ; Humans ; Acid Anhydride Hydrolases/metabolism ; Saccharomyces cerevisiae/metabolism ; Eukaryotic Cells/metabolism ; Polyphosphates/metabolism ; Mammals/metabolism
    Chemical Substances endopolyphosphatase (EC 3.6.1.10) ; Acid Anhydride Hydrolases (EC 3.6.-) ; Polyphosphates
    Language English
    Publishing date 2023-02-02
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 212746-5
    ISSN 1873-3468 ; 0014-5793
    ISSN (online) 1873-3468
    ISSN 0014-5793
    DOI 10.1002/1873-3468.14584
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  6. Article ; Online: An Anatheistic Wager for Bioethics.

    McCarthy, Michael

    The American journal of bioethics : AJOB

    2021  Volume 21, Issue 6, Page(s) 26–28

    MeSH term(s) Bioethics ; Dissent and Disputes ; Ethicists ; Humans ; Morals ; Religion
    Language English
    Publishing date 2021-06-07
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2021.1915428
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    Zs.A 6814: Show issues Location:
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  7. Book: Cognitive behavioral therapy for sexual dysfunction

    Metz, Michael E. / Epstein, Norman / McCarthy, Barry

    2018  

    Title variant Cognitive-behavioral therapy for sexual dysfunction
    Author's details Michael E. Metz, Norman B. Epstein nd Barry McCarthy
    Language English
    Size viii, 244 S., Illustrationen
    Publisher Routledge
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT016915750
    ISBN 978-0-415-87408-3 ; 978-0-415-87407-6 ; 0-415-87407-6 ; 9780203863459 ; 0-415-87408-4 ; 0203863453
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2018 A 82 available for loan (reading room) Lesesaal EG

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  8. Article ; Online: Hyperfine-Resolved Rotational Spectroscopy of Phenyl Radical.

    Changala, P Bryan / McCarthy, Michael C

    The journal of physical chemistry letters

    2023  Volume 14, Issue 23, Page(s) 5370–5376

    Abstract: We present an analysis of the hyperfine-resolved rotational spectrum of gas-phase phenyl radical, ...

    Abstract We present an analysis of the hyperfine-resolved rotational spectrum of gas-phase phenyl radical,
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.3c01243
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  9. Article ; Online: Acquired Cystic Disease-Associated Renal Cell Carcinoma.

    McCarthy, Michael R / Gupta, Sounak / Erickson, Lori A

    Mayo Clinic proceedings

    2023  Volume 98, Issue 4, Page(s) 637–638

    MeSH term(s) Humans ; Carcinoma, Renal Cell/pathology ; Kidney Neoplasms/pathology ; Renal Dialysis ; Kidney Failure, Chronic
    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.01.016
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  10. Article ; Online: Obituary for Professor Emeritus Howard D. Dorfman, MD, 1928-2023.

    Klein, Michael J / McCarthy, Edward F / Haramati, Nogah / Bencardino, Jenny T

    Skeletal radiology

    2024  Volume 53, Issue 5, Page(s) 1031–1032

    Language English
    Publishing date 2024-02-06
    Publishing country Germany
    Document type Editorial
    ZDB-ID 527592-1
    ISSN 1432-2161 ; 0364-2348
    ISSN (online) 1432-2161
    ISSN 0364-2348
    DOI 10.1007/s00256-024-04606-6
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