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  1. Book: 1st joint meeting of the International Society for Autonomic Neuroscience and the American Autonomic Society (ISAN/AAS 2011)

    Chapleau, Mark W.

    [Búzios, Rio de Janeiro, Brazil, September 12 - 16, 2011] ; [program ; abstracts]

    (Autonomic neuroscience ; 163,1/2 = Special issue)

    2011  

    Institution International Society for Autonomic Neuroscience
    American Autonomic Society
    Author's details guest ed.: Mark W. Chapleau
    Series title Autonomic neuroscience ; 163,1/2 = Special issue
    Collection
    Language English
    Size S. 1 - 133
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT016939860
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Differential engagement of inhibitory and excitatory cardiopulmonary reflexes by capsaicin and phenylbiguanide in C57BL/6 mice.

    Larson, Robert A / Chapleau, Mark W

    American journal of physiology. Regulatory, integrative and comparative physiology

    2023  Volume 324, Issue 3, Page(s) R336–R344

    Abstract: The Bezold-Jarisch reflex is a powerful inhibitory reflex initiated by activation of cardiopulmonary vagal nerves during myocardial ischemia, hemorrhage, and orthostatic stress leading to bradycardia, vasodilation, hypotension, and vasovagal syncope. ... ...

    Abstract The Bezold-Jarisch reflex is a powerful inhibitory reflex initiated by activation of cardiopulmonary vagal nerves during myocardial ischemia, hemorrhage, and orthostatic stress leading to bradycardia, vasodilation, hypotension, and vasovagal syncope. This clinically relevant reflex has been studied by measuring heart rate (HR) and mean arterial pressure (MAP) responses to injections of a variety of chemical compounds. We hypothesized that reflex responses to different compounds vary due to differential activation of vagal afferent subtypes and/or variable coactivation of excitatory afferents. HR and MAP responses to intravenous injections of the transient receptor potential vanilloid-1 (TRPV1) agonist capsaicin and the serotonin 5-HT
    MeSH term(s) Mice ; Animals ; Capsaicin/pharmacology ; Serotonin ; Mice, Inbred C57BL ; Bradycardia ; Heart Rate ; Reflex/physiology ; Blood Pressure
    Chemical Substances Capsaicin (S07O44R1ZM) ; phenyl biguanide (W8PKA3T2I3) ; Serotonin (333DO1RDJY)
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 603839-6
    ISSN 1522-1490 ; 0363-6119
    ISSN (online) 1522-1490
    ISSN 0363-6119
    DOI 10.1152/ajpregu.00102.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Neuro-cardiovascular regulation

    Chapleau, Mark W.

    from molecules to man ; [result of a Conference Entitled Baroreceptor and Cardiopulmonary Receptor Reflexes ... held August 23 - 27, 2000, in Iowa City, Iowa]

    (Annals of the New York Academy of Sciences ; 940)

    2001  

    Event/congress Conference Entitled Baroreceptor and Cardiopulmonary Receptor Reflexes (2000, IowaCityIowa)
    Author's details ed. by Mark W. Chapleau
    Series title Annals of the New York Academy of Sciences ; 940
    Collection
    Keywords Kardiovaskuläres System ; Regulation ; Pressorezeptor ; Blutkreislauf ; Blutdruck
    Subject Barorezeptor ; Kreislauf ; Blutzirkulation ; Blutbewegung ; Blutfluss ; Blutstrom ; Blutströmung ; Herz-Kreislauf-System ; Cardiovasculäres System
    Language English
    Size XXII, 546 S. : Ill., graph. Darst.
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT013138049
    ISBN 1-57331-344-0 ; 1-57331-345-9 ; 978-1-57331-344-5 ; 978-1-57331-345-2
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Increased cardiac sympathetic activity: Cause or compensation in vasovagal syncope?

    Larson, Robert A / Chapleau, Mark W

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2018  Volume 28, Issue 3, Page(s) 265–266

    MeSH term(s) Animals ; Heart ; Humans ; Models, Animal ; Syncope, Vasovagal ; Tilt-Table Test
    Language English
    Publishing date 2018-04-03
    Publishing country Germany
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-018-0524-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Contributions of skeletal muscle myopathy to heart failure: novel mechanisms and therapies. Introduction.

    Chapleau, Mark W

    Experimental physiology

    2014  Volume 99, Issue 4, Page(s) 607–608

    MeSH term(s) Animals ; Exercise Tolerance ; Heart Failure/complications ; Heart Failure/metabolism ; Heart Failure/physiopathology ; Heart Failure/therapy ; Humans ; Muscle Fatigue ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiopathology ; Muscular Diseases/complications ; Muscular Diseases/metabolism ; Muscular Diseases/physiopathology ; Muscular Diseases/therapy ; Phenotype ; Prognosis ; Risk Factors
    Language English
    Publishing date 2014-04-01
    Publishing country England
    Document type Introductory Journal Article ; Journal Article ; Video-Audio Media
    ZDB-ID 1016295-1
    ISSN 1469-445X ; 0958-0670
    ISSN (online) 1469-445X
    ISSN 0958-0670
    DOI 10.1113/expphysiol.2013.074294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Carotid body chemoreceptors: physiology, pathology, and implications for health and disease.

    Iturriaga, Rodrigo / Alcayaga, Julio / Chapleau, Mark W / Somers, Virend K

    Physiological reviews

    2021  Volume 101, Issue 3, Page(s) 1177–1235

    Abstract: The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases ... ...

    Abstract The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O
    MeSH term(s) Animals ; Autonomic Nervous System/metabolism ; Cardiovascular System/metabolism ; Carotid Body/metabolism ; Chemoreceptor Cells/metabolism ; Humans ; Hypoxia/metabolism
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 209902-0
    ISSN 1522-1210 ; 0031-9333
    ISSN (online) 1522-1210
    ISSN 0031-9333
    DOI 10.1152/physrev.00039.2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Plasticity of cerebral microvascular structure and mechanics during hypertension and following recovery of arterial pressure.

    Sabharwal, Rasna / Chapleau, Mark W / Gerhold, Thomas D / Baumbach, Gary L / Faraci, Frank M

    American journal of physiology. Heart and circulatory physiology

    2022  Volume 323, Issue 6, Page(s) H1108–H1117

    Abstract: Changes in vascular structure contribute to vascular events and loss of brain health. We examined changes in cerebral arterioles at the onset of hypertension and the hypothesis that alterations during hypertension would recover with the return of mean ... ...

    Abstract Changes in vascular structure contribute to vascular events and loss of brain health. We examined changes in cerebral arterioles at the onset of hypertension and the hypothesis that alterations during hypertension would recover with the return of mean arterial pressure (MAP) to normal. MAP was measured with radiotelemetry in awake male C57BL/6J mice at baseline and during infusion of vehicle or angiotensin II (ANG II, 1.4 mg/kg/day using osmotic pumps) for 28 days, followed by a 28-day recovery. With ANG II treatment, MAP increased through
    MeSH term(s) Animals ; Mice ; Male ; Arterial Pressure ; Mice, Inbred C57BL ; Hypertension ; Blood Pressure ; Arterioles ; Angiotensin II/pharmacology
    Chemical Substances Angiotensin II (11128-99-7)
    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 603838-4
    ISSN 1522-1539 ; 0363-6135
    ISSN (online) 1522-1539
    ISSN 0363-6135
    DOI 10.1152/ajpheart.00292.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Neurohormones in Vasovagal Syncope: Are They Important?

    Williford, Noah N / Chapleau, Mark W / Olshansky, Brian

    Journal of the American Heart Association

    2019  Volume 8, Issue 12, Page(s) e013129

    Abstract: See Article Torabi et al. ...

    Abstract See Article Torabi et al.
    MeSH term(s) Cardiovascular System ; Humans ; Neurotransmitter Agents ; Syncope, Vasovagal
    Chemical Substances Neurotransmitter Agents
    Language English
    Publishing date 2019-06-18
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.119.013129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats.

    Abboud, Francois M / Cicha, Michael Z / Ericsson, Aaron / Chapleau, Mark W / Singh, Madhu V

    Frontiers in physiology

    2021  Volume 12, Page(s) 752924

    Abstract: Hypertension is regulated by immunological components. Spontaneously hypertensive rats (SHR) display a large population of proinflammatory CD161 + immune cells. We investigated the effect of early post-natal gut microbiota on the development of the ... ...

    Abstract Hypertension is regulated by immunological components. Spontaneously hypertensive rats (SHR) display a large population of proinflammatory CD161 + immune cells. We investigated the effect of early post-natal gut microbiota on the development of the immune system and resulting hypertension in the SHR. We first examined the microbial populations in the fecal samples of SHR and normotensive control WKY using 16S rDNA sequencing. We found that in the newborn SHR (1-week old) the gut microbiota was qualitatively and quantitatively different from the newborns of normotensive WKY. The representation of the predominant bacterial phylum Proteobacteria was significantly less in 1-week old SHR pups than in WKY (94.5% Proteobacteria in WKY vs. 65.2% in SHR neonates). Even within the phylum Proteobacteria, the colonizing genera in WKY and SHR differed dramatically. Whereas WKY microbiota was predominantly comprised of
    Language English
    Publishing date 2021-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2021.752924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: CIH: from sleep apnea to breath-hold diving. Is sympathetic activation inevitable?

    Chapleau, Mark W

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2010  Volume 20, Issue 2, Page(s) 53–55

    MeSH term(s) Apnea/physiopathology ; Blood Pressure/physiology ; Carotid Body/physiology ; Chronic Disease ; Diving/physiology ; Humans ; Hypoxia/physiopathology ; Pulmonary Ventilation/physiology ; Signal Transduction/physiology ; Sleep Apnea Syndromes/physiopathology ; Sympathetic Nervous System/physiology
    Language English
    Publishing date 2010-04-20
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-010-0064-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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