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Article ; Online: Human presence as a determinant of the occurrence of mammals in a high diversity protected area of Cerrado-Caatinga ecotone in Brazil.

Pereira, Adriele A / Rosa, Clarissa / Faria, Lucas D B / Silva, Lucas G DA / Passamani, Marcelo

Anais da Academia Brasileira de Ciencias

2023 Volume 95, Issue 1, Page(s) e20201869

Abstract: The Cerrado domain and its biodiversity has suffered several anthropogenic influences. Our objective was to evaluate the influence of biotic and anthropic variables on the mammal community in a protected area in the Cerrado-Caatinga ecotone. For this we ... ...

Abstract	The Cerrado domain and its biodiversity has suffered several anthropogenic influences. Our objective was to evaluate the influence of biotic and anthropic variables on the mammal community in a protected area in the Cerrado-Caatinga ecotone. For this we sampled the mammals using camera traps (4,072 days/trap) for 16 months. We used generalized mixed linear models (GLMM) with model selection via Akaike's Information Criteria corrected for small sample size (AICc) to assess the influence of variables on richness, abundance and functional groups of mammals. We made a total of 663 photographic records of 16 species of medium and large mammals. The richness and number of mammals was negatively influenced by the distance to human settlements while carnivores were not affected by any of the variables evaluated, herbivores and generalists were more common in areas closer from human habitation. Despite the presence of large areas of native vegetation, our results show that there is a dominance of common and generalist species. The protected area is vulnerable to different sources of human pressure and the design and implementation of a management plan can be a key tool for protecting biodiversity and regulating the use of natural resources by local communities.
MeSH term(s)	Animals ; Humans ; Brazil ; Mammals ; Biodiversity ; Herbivory ; Linear Models
Language	English
Publishing date	2023-05-08
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2046885-4
ISSN	1678-2690 ; 0001-3765
ISSN (online)	1678-2690
ISSN	0001-3765
DOI	10.1590/0001-3765202320201869
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon.

Paixão, Daniela da Silva / Portela Madeira, Fernanda / Costa de Jesus, Adila / Paixão, Hêmilly Caroline da Silva / Camargo, Juliana de Souza Almeida Aranha / Ribeiro, Mariane Albuquerque Lima / José Ramos, Leandro / de Oliveira, Jader / Aristeu da Rosa, João / Bernarde, Paulo Sérgio / Pereira Relvas, Antonieta / Basano, Sergio de Almeida / Aranha Camargo, Luis Marcelo / Meneguetti, Dionatas Ulises de Oliveira

Pathogens (Basel, Switzerland)

2024 Volume 13, Issue 2

Abstract: Chagas disease (CD) is a typical tropical illness caused ... ...

Abstract	Chagas disease (CD) is a typical tropical illness caused by
Language	English
Publishing date	2024-02-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens13020176
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Article ; Online: Synergy between polypyrrol and benzoic acid against antibiotic-resistant Salmonella spp.

Garcez, Dino César Pereira / Ribeiro, Gabrielle / Kominkiewicz, Marcelo / da Costa, Mateus Matiuzzi / Chideroli, Roberta Torres / Rosa, Danillo Sales / Dos Santos, Isaac Emanuel Pereira / Morante, Vitor Hugo Penariol / Silveira, Simone / Girardini, Lilian Kolling

Journal of applied microbiology

2023 Volume 134, Issue 9

Abstract: Aims: The purpose was to characterize Salmonella Heidelberg (SH) and Minnesota (SM) isolates in terms of their resistance and persistence profile and to assess the antimicrobial effect of benzoic acid (BA) and polypyrrole (PPy).: Methods and results: ...

Abstract	Aims: The purpose was to characterize Salmonella Heidelberg (SH) and Minnesota (SM) isolates in terms of their resistance and persistence profile and to assess the antimicrobial effect of benzoic acid (BA) and polypyrrole (PPy). Methods and results: The 20 isolates from broiler litter drag swabs were submitted to antibiogram and efflux pump expression. The minimum inhibitory/bactericidal concentration (MIC/MBC) of the compounds, synergistic activity, time kill, biofilm production, presence of related genes, and molecular docking between compounds and bacterial target sites were evaluated. All isolates showed multidrug resistance (MDR) and BA and PPy showed mean MIC (1750 and 342 µg ml-1) and MBC (3167 and 1000 µg ml-1), respectively. None of the isolates expressed an efflux pump. The compounds showed synergism against an SH isolate and reduced the count by 3 logs in the presence of the compounds after 4 h. Most isolates (16/20) produced weak to moderate biofilm and 17 showed genes related to biofilm. The compounds interacted with two essential proteins, 3,4-dihydroxy-2-butanone 4-phosphate synthase proteins and ferritin-like domain-containing protein, in bacterial metabolism at different target sites. Conclusions: It can be concluded that BA and PPy showed activity on SH and SM, MDR, and biofilm producers, with a potential synergistic effect.
MeSH term(s)	Animals ; Benzoic Acid/pharmacology ; Chickens ; Manure ; Molecular Docking Simulation ; Polymers ; Pyrroles/pharmacology ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Benzoic Acid (8SKN0B0MIM) ; Manure ; Polymers ; Pyrroles ; 3,4-dihydroxy-2-butanone ; Anti-Bacterial Agents
Language	English
Publishing date	2023-09-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1358023-1
ISSN	1365-2672 ; 1364-5072
ISSN (online)	1365-2672
ISSN	1364-5072
DOI	10.1093/jambio/lxad186
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Article ; Online: Impact of Metal Accumulation on Photosynthetic Pigments, Carbon Assimilation, and Oxidative Metabolism in Mangroves Affected by the Fundāo Dam Tailings Plume

Veronica D’Addazio / Monica Maria Pereira Tognella / Adriano Alves Fernandes / Antelmo Ralph Falqueto / Marcelo Barcellos da Rosa / Ivoney Gontijo / Marcelo Antônio de Oliveira

Coasts, Vol 3, Iss 8, Pp 125-

2023 Volume 144

Abstract: The effects of iron, manganese, zinc, copper, and lead on the chlorophyll content, carbon assimilation, and the antiradical activity of Rhizophora mangle and Laguncularia racemosa were evaluated in regions affected by the Fundão dam disruption in Brazil. ...

Abstract	The effects of iron, manganese, zinc, copper, and lead on the chlorophyll content, carbon assimilation, and the antiradical activity of Rhizophora mangle and Laguncularia racemosa were evaluated in regions affected by the Fundão dam disruption in Brazil. The mine waste which settled and accumulated in the sediments could represent long-term contamination. It can be expected that the iron oxyhydroxides deposited in the sediments will be solubilized, leading to chronic contamination by trace metals and the accumulation of these metals in the biota. In this sense, biological indicators prove to be important tools to assess this type of damage. The different bioaccumulation of metals by the species revealed that R. mangle was more impacted by Mn and Cu and that L. racemosa showed alterations in its physiological responses in the presence of Cu, Zn, and Fe. The concentration of these metals in the leaves, with values above previous local reference limits, was associated with reductions in the chlorophyll-a and chlorophyll-b content and carbon assimilation, mainly in L. racemosa . The antiradical activity was also altered, suggesting a lower ability of both species to eliminate reactive oxygen species (ROS). A possible reason for the symptoms of oxidative stress may be due to the reduced efficiency of antioxidant defense by Cu 2+ and Zn 2+ . In addition, the presence of Pb in the leaf tissue may be toxic to the fauna and the bioaccumulation of this metal and trace elements can be a way to transfer them into the food web by biomagnification.
Keywords	chlorophyll ; DPPH • ; mangrove ; Rhizophora mangle ; Laguncularia racemosa ; potentially toxic metal ; Environmental sciences ; GE1-350 ; Harbors and coast protective works. Coastal engineering. Lighthouses ; TC203-380 ; Geography (General) ; G1-922
Subject code	333
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Social cognition and psychosocial functioning in schizophrenia and bipolar disorder: Theory of mind as a key to understand schizophrenia dysfunction.

de Sales, Sarah Corrêa / Philippsen, Marieli / de Jesus, Letícia Stephane / Carriello, Marcelo Alves / Alvim, Pedro Henrique Pereira / Costa, Diogo Fernando Bornancin / da Rosa, Laura Canani / Hasse-Sousa, Mathias / Czepielewski, Letícia Sanguinetti / Massuda, Raffael

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

2023 Volume 77, Page(s) 12–20

Abstract: Functional impairment is a common symptom in schizophrenia (SZ) and bipolar disorder (BD). Pharmacological treatments have limited functional recovery in both disorders. Social cognition, a cognitive process, has been associated with functioning in ... ...

Abstract	Functional impairment is a common symptom in schizophrenia (SZ) and bipolar disorder (BD). Pharmacological treatments have limited functional recovery in both disorders. Social cognition, a cognitive process, has been associated with functioning in mental disorders. Theory of mind (ToM) is considered a key factor in understanding the social cognitive deficits in SZ and BD. Our study aimed to investigate the relationship between ToM and functioning in SZ, BD, and healthy controls (HC) and compare ToM and functioning impairments between groups. A total of 208 participants (HC n = 69; BD n = 89; SZ n = 50) were evaluated with the Functioning Assessment Short Test (FAST), Reading the Mind in the Eyes Test (RMET), the Vocabulary subtest of the Wechsler Abbreviated Scale for Intelligence (WASI) and the Hopkins Verbal Learning Test - Revised (HVLT-R). Comparisons of RMET between low- and high-functioning individuals and multiple linear regression analyses were conducted for each group. Multiple regression analysis revealed that the association between ToM and psychosocial functioning was observed only in SZ (β = -1.352, p = 0.008). Low-functioning SZ participants showed a lower ToM performance compared to participants with high-functioning SZ (t = 1.80, p = 0.039, Cohen's d = 0.938). No significant associations were found in the other groups. ToM is essential to understand the functional impairment in SZ, more than in BD. Furthermore, ToM may be a primary target for intervention strategies in improving functioning in SZ.
MeSH term(s)	Humans ; Schizophrenia/diagnosis ; Bipolar Disorder/diagnosis ; Social Cognition ; Theory of Mind ; Psychosocial Functioning ; Cognition ; Neuropsychological Tests
Language	English
Publishing date	2023-09-01
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1082947-7
ISSN	1873-7862 ; 0924-977X
ISSN (online)	1873-7862
ISSN	0924-977X
DOI	10.1016/j.euroneuro.2023.08.483
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Zs.A 3288: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Morphofunctional Improvement of the Facial Nerve and Muscles with Repair Using Heterologous Fibrin Biopolymer and Photobiomodulation.

Bueno, Cleuber Rodrigo de Souza / Tonin, Maria Clara Cassola / Buchaim, Daniela Vieira / Barraviera, Benedito / Ferreira Junior, Rui Seabra / Santos, Paulo Sérgio da Silva / Reis, Carlos Henrique Bertoni / Pastori, Cláudio Maldonado / Pereira, Eliana de Souza Bastos Mazuqueli / Nogueira, Dayane Maria Braz / Cini, Marcelo Augusto / Rosa Junior, Geraldo Marco / Buchaim, Rogerio Leone

Pharmaceuticals (Basel, Switzerland)

2023 Volume 16, Issue 5

Abstract: Peripheral nerve injuries impair the patient's functional capacity, including those occurring in the facial nerve, which require effective medical treatment. Thus, we investigated the use of heterologous fibrin biopolymer (HFB) in the repair of the ... ...

Abstract	Peripheral nerve injuries impair the patient's functional capacity, including those occurring in the facial nerve, which require effective medical treatment. Thus, we investigated the use of heterologous fibrin biopolymer (HFB) in the repair of the buccal branch of the facial nerve (BBFN) associated with photobiomodulation (PBM), using a low-level laser (LLLT), analyzing the effects on axons, muscles facials, and functional recovery. This experimental study used twenty-one rats randomly divided into three groups of seven animals, using the BBFN bilaterally (the left nerve was used for LLLT): Control group-normal and laser (CGn and CGl); Denervated group-normal and laser (DGn and DGl); Experimental Repair Group-normal and laser (ERGn and ERGl). The photobiomodulation protocol began in the immediate postoperative period and continued for 5 weeks with a weekly application. After 6 weeks of the experiment, the BBFN and the perioral muscles were collected. A significant difference (
Language	English
Publishing date	2023-04-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2193542-7
ISSN	1424-8247
ISSN	1424-8247
DOI	10.3390/ph16050653
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Article ; Online: Disruption of Redox Homeostasis by Alterations in Nitric Oxide Synthase Activity and Tetrahydrobiopterin along with Melanoma Progression.

Soares, Jaqueline Pereira Moura / Gonçalves, Diego Assis / de Sousa, Ricardo Xisto / Mouro, Margareth Gori / Higa, Elisa M S / Sperandio, Letícia Paulino / Vitoriano, Carolina Moraes / Rosa, Elisa Bachir Santa / Santos, Fernanda Oliveira Dos / de Queiroz, Gustavo Nery / Yamaguchi, Roberta Sessa Stilhano / Pereira, Gustavo / Icimoto, Marcelo Yudi / Melo, Fabiana Henriques Machado de

International journal of molecular sciences

2022 Volume 23, Issue 11

Abstract: Cutaneous melanoma emerges from the malignant transformation of melanocytes and is the most aggressive type of skin cancer. The progression can occur in different stages: radial growth phase (RGP), vertical growth phase (VGP), and metastasis. Reactive ... ...

Abstract	Cutaneous melanoma emerges from the malignant transformation of melanocytes and is the most aggressive type of skin cancer. The progression can occur in different stages: radial growth phase (RGP), vertical growth phase (VGP), and metastasis. Reactive oxygen species contribute to all phases of melanomagenesis through the modulation of oncogenic signaling pathways. Tetrahydrobiopterin (BH4) is an important cofactor for NOS coupling, and an uncoupled enzyme is a source of superoxide anion (O
MeSH term(s)	Biopterins/analogs & derivatives ; Biopterins/metabolism ; Homeostasis ; Humans ; Melanoma/pathology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Oxidation-Reduction ; Phosphatidylinositol 3-Kinases/metabolism ; Skin Neoplasms
Chemical Substances	Biopterins ; Nitric Oxide (31C4KY9ESH) ; Nitric Oxide Synthase (EC 1.14.13.39) ; Nitric Oxide Synthase Type III (EC 1.14.13.39) ; sapropterin (EGX657432I)
Language	English
Publishing date	2022-05-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms23115979
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Article ; Online: Lethal and sublethal effects of insecticides used in the management of Plutella xylostella (Lepidoptera: Plutellidae) on the predator Cycloneda sanguinea L. (Coleoptera: Coccinellidae).

da Silva, Wanderson Rosa / Pereira, Renata Cunha / Mendonça, Laís Viana Paes / Peçanha, Ludimila Simões / de Sales Abreu, Letícia Moamad / Abib, Pedro Henrique Nogueira / Samuels, Richard Ian / Picanço, Marcelo Coutinho / Silva, Gerson Adriano

Pest management science

2022 Volume 78, Issue 10, Page(s) 4397–4406

Abstract: Background: The application of synthetic insecticides is the main strategy used to reduce the damage caused by the diamondback moth Plutella xylostella in commercial Brassica crops. However, incorrect insecticide use can cause biological and ecological ... ...

Abstract	Background: The application of synthetic insecticides is the main strategy used to reduce the damage caused by the diamondback moth Plutella xylostella in commercial Brassica crops. However, incorrect insecticide use can cause biological and ecological disturbances in agroecosystems. Cycloneda sanguinea is a generalist voracious predator and is distributed widely in cultivated and noncultivated ecosystems. This study investigated the efficiency of four insecticides for the control of P. xylostella and the lethal and sublethal effects of these insecticides on C. sanguinea. Results: Spinosad (92% mortality) and chlorfenapyr (76% mortality) were highly toxic to P. xylostela. However, chlorantraniliprole (10% mortality) and methomyl (no mortality) were ineffective against this pest. Chlorantraniliprole was the only insecticide that was highly toxic to C. sanguinea by contact (90% mortality), however, it was nontoxic following the ingestion of chlorantraniliprole-contaminated aphids. Interestingly, ingestion of prey contaminated with methomyl and chlorfenapyr was highly toxic (100% mortality) to C. sanguinea. Spinosad was nontoxic to C. sanguinea via exposure to contaminated surfaces and following ingestion of contaminated prey. However, direct contact of the insects with both methomyl and spinosad significantly affected C. sanguinea flight activity (vertical flight and free-fall flight), whereas chlorfenapyr impacted vertical flight only. Conclusion: These findings showed that chlorantraniliprole was not only ineffective for the control of P. xylostela, but was also highly toxic to C. sanguinea. The results indicated that spinosad was efficient against P. xylostela and was of low toxicity to C. sanguinea; however, the deleterious effects of this insecticide on flight behavior could result in reduced predatory efficiency. © 2022 Society of Chemical Industry.
MeSH term(s)	Animals ; Coleoptera ; Ecosystem ; Insecticide Resistance ; Insecticides/toxicity ; Larva ; Methomyl/toxicity ; Moths
Chemical Substances	Insecticides ; Methomyl (1NQ08HN02S)
Language	English
Publishing date	2022-07-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2001705-4
ISSN	1526-4998 ; 1526-498X
ISSN (online)	1526-4998
ISSN	1526-498X
DOI	10.1002/ps.7060
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Article ; Online: Gestão do conhecimento e inovação em startups Catarinenses

Mariana Pereira da Silva / Larissa Lara Gabiatti / Marcelo Macedo / Nina Rosa Cruz Gerges

Encontros Bibli (2018)

2018

Abstract: O objetivo deste artigo é identificar os conhecimentos críticos voltados para o incremento do processo de inovação em startups catarinenses. O procedimento metodológico adotado é um estudo de casos múltiplos. Os resultados mostram que nem todos os ... ...

Abstract	O objetivo deste artigo é identificar os conhecimentos críticos voltados para o incremento do processo de inovação em startups catarinenses. O procedimento metodológico adotado é um estudo de casos múltiplos. Os resultados mostram que nem todos os conhecimentos estudados nas empresas podem ser considerados como críticos para o incremento da inovação. Ainda foi possível constatar que nem sempre a prática organizacional está de acordo com a literatura.
Keywords	Inovação ; Startup ; Gestão do Conhecimento ; Conhecimento Crítico ; Bibliography. Library science. Information resources ; Z
Language	English
Publishing date	2018-06-01T00:00:00Z
Publisher	Universidade Federal de Santa Catarina (UFSC)
Document type	Article ; Online
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Article ; Online: Development of a membrane and a bilayer of chitosan, gelatin, and polyhydroxybutyrate to be used as wound dressing for the regeneration of rat excisional wounds.

Barbosa, Joana Lobato / de Melo, Mariane Izabella Abreu / da Silva Cunha, Pricila / de Miranda, Marcelo Coutinho / Barrioni, Breno Rocha / Moreira, Cheisy Daiana Freitas / da Fonseca Ferreira, Andrea / Arantes, Rosa Maria Esteves / de Sá, Marcos Augusto / de Magalhães Pereira, Marivalda / Rodrigues, Michele Angela / Novikoff, Silviene / Gomes, Dawidson Assis / de Goes, Alfredo Miranda

Journal of biomedical materials research. Part A

2023 Volume 112, Issue 1, Page(s) 82–98

Abstract: The skin is the largest organ in the human body that acts as a protective barrier from the outside environment. Certain dermatological pathologies or significant skin lesions can result in serious complications. Several studies have focused on the ... ...

Abstract	The skin is the largest organ in the human body that acts as a protective barrier from the outside environment. Certain dermatological pathologies or significant skin lesions can result in serious complications. Several studies have focused on the development of tissue-engineered skin substitutes. In this study, a new bilayer scaffold composed of a chitosan-gelatin membrane and a chitosan-polyhydroxybutyrate (PHB) porous matrix was synthesized and populated with human adipose-derived mesenchymal stem cells (hASCs) to be potentially used for wound dressing applications. By combining this membrane and porous matrix with the stem cells, we aimed to provide immunomodulation and differentiation capabilities for the wound environment, as well as mechanical strength and biocompatibility for the underlying tissue. The membrane was prepared from the mixture of chitosan and gelatin in a 2:1 ratio and the porous matrix was prepared from the mixture of chitosan and PHB, in equal proportions to form a final solution at 2.5% (m/v). Fourier transform infrared spectroscopy analysis showed the formation of blends, and micro-computed tomography, scanning electron microscopy and atomic force microscopy images demonstrated membrane roughness and matrix porosity. The MTT assay showed that the scaffolds were biocompatible with hASC. The membrane and the bilayer were used as dressing and support for cell migration in the dorsal excisional wound model in Wistar rats. Histological and gene transcriptional analyses showed that the animals that received the scaffolds regenerated the hair follicles in the deep dermis in the central region of the wound. Our results demonstrate the potential of these new biomaterials as dressings in wound healing studies, favoring tissue regeneration.
MeSH term(s)	Rats ; Humans ; Animals ; Chitosan/chemistry ; Gelatin/pharmacology ; Gelatin/chemistry ; X-Ray Microtomography ; Rats, Wistar ; Bandages ; Tissue Scaffolds/chemistry
Chemical Substances	Chitosan (9012-76-4) ; Gelatin (9000-70-8) ; polyhydroxybutyrate
Language	English
Publishing date	2023-10-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2099989-6
ISSN	1552-4965 ; 1549-3296 ; 0021-9304
ISSN (online)	1552-4965
ISSN	1549-3296 ; 0021-9304
DOI	10.1002/jbm.a.37616
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