Article ; Online: Slope of the estimated glomerular filtration rate and its associated factors among individuals with chronic kidney disease in the general Japanese population.
Clinical and experimental nephrology
2024
Abstract: Background: To suppress the incidence of end-stage kidney disease, we need to identify chronic kidney disease (CKD) patients with a high risk of rapid decline in the estimated glomerular filtration rate (eGFR). However, the current status of eGFR slope ... ...
Abstract | Background: To suppress the incidence of end-stage kidney disease, we need to identify chronic kidney disease (CKD) patients with a high risk of rapid decline in the estimated glomerular filtration rate (eGFR). However, the current status of eGFR slope and its associated factors in the Japanese population have not been fully elucidated. Methods: Among examinees aged 40-70 years in the 2014 Specific Health Checkup conducted by the National Health Insurance in Kobe, Japan (n = 61,985), we prospectively observed 7291 examinees with CKD stage G3 from 2014 to 2018. Results: Until 2018, 4221 examinees continued to undergo annual SHCs for a total of five checkups per subject and had available records of all necessary data. The median eGFR change was -0.22 ml/min/1.73 m Conclusion: Most Japanese CKD stage-G3 subjects had a very slow decline in eGFR. A small proportion of CKD individuals who have a predictive factor of rapid eGFR decline should receive considerable attention from a nephrologist. |
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Language | English |
Publishing date | 2024-02-10 |
Publishing country | Japan |
Document type | Journal Article |
ZDB-ID | 1338768-6 |
ISSN | 1437-7799 ; 1342-1751 |
ISSN (online) | 1437-7799 |
ISSN | 1342-1751 |
DOI | 10.1007/s10157-024-02466-x |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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