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  1. Article ; Online: Optimal Timing of Cholecystectomy for Severe Acute Pancreatitis and Understanding Complications and Comorbidities-Reply.

    Di Martino, Marcello / Ielpo, Benedetto / Podda, Mauro

    JAMA surgery

    2024  Volume 159, Issue 4, Page(s) 466–467

    MeSH term(s) Humans ; Pancreatitis/surgery ; Pancreatitis/etiology ; Acute Disease ; Cholecystectomy/adverse effects ; Cholecystectomy, Laparoscopic/adverse effects ; Retrospective Studies
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2023.6932
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  2. Article ; Online: Pancreatic cancer surgery.

    Di Martino, Marcello / El Boghdady, Michael

    BMC surgery

    2023  Volume 23, Issue 1, Page(s) 196

    MeSH term(s) Humans ; Pancreatic Neoplasms/surgery ; Pancreas/surgery ; Pancreatectomy ; Pancreatic Neoplasms
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Editorial
    ZDB-ID 2050442-1
    ISSN 1471-2482 ; 1471-2482
    ISSN (online) 1471-2482
    ISSN 1471-2482
    DOI 10.1186/s12893-023-02091-7
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  3. Article ; Online: ASO Author Reflections: Peri-operative Chemotherapy for Resectable Colorectal Liver Metastases.

    Di Martino, Marcello / Primavesi, Florian

    Annals of surgical oncology

    2022  Volume 29, Issue 11, Page(s) 6843–6844

    MeSH term(s) Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Hepatectomy ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-022-12176-x
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    Zs.A 4042: Show issues Location:
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  4. Article ; Online: Percutaneous cholecystostomy in elderly patients with acute cholecystitis: a systematic review and meta-analysis.

    Terrone, Alfonso / Di Martino, Marcello / Saeidi, Sara / Ranucci, Chiara / Di Saverio, Salomone / Giuliani, Antonio

    Updates in surgery

    2024  Volume 76, Issue 2, Page(s) 363–373

    Abstract: Percutaneous cholecystostomy (PC) is often preferred over early cholecystectomy (EC) for elderly patients presenting with acute cholecystitis (AC). However, there is a lack of solid data on this issue. Following the PRISMA guidelines, we searched the ... ...

    Abstract Percutaneous cholecystostomy (PC) is often preferred over early cholecystectomy (EC) for elderly patients presenting with acute cholecystitis (AC). However, there is a lack of solid data on this issue. Following the PRISMA guidelines, we searched the Medline and Web of Science databases for reports published before December 2022. Studies that assessed elderly patients (aged 65 years and older) with AC treated using PC, in comparison with those treated with EC, were included. Outcomes analyzed were perioperative outcomes and readmissions. The literature search yielded 3279 records, from which 7 papers (1208 patients) met the inclusion criteria. No clinical trials were identified. Patients undergoing PC comprised a higher percentage of cases with ASA III or IV status (OR 3.49, 95%CI 1.59-7.69, p = 0.009) and individuals with moderate to severe AC (OR 1.78, 95%CI 1.00-3.16, p = 0.05). No significant differences were observed in terms of mortality and morbidity. However, patients in the PC groups exhibited a higher rate of readmissions (OR 3.77, 95%CI 2.35-6.05, p < 0.001) and a greater incidence of persistent or recurrent gallstone disease (OR 12.60, 95%CI 3.09-51.38, p < 0.001). Elderly patients selected for PC, displayed greater frailty and more severe AC, but did not exhibit increased post-interventional morbidity and mortality compared to those undergoing EC. Despite their inferior life expectancy, they still presented a greater likelihood of persistent or recurrent disease compared to the control group.
    MeSH term(s) Aged ; Humans ; Cholecystostomy/adverse effects ; Treatment Outcome ; Cholecystitis, Acute/surgery ; Cholecystitis, Acute/etiology ; Cholecystectomy/adverse effects ; Gallstones/surgery ; Retrospective Studies
    Language English
    Publishing date 2024-02-19
    Publishing country Italy
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01736-9
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    Zs.B 101: Show issues Location:
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  5. Article ; Online: A comprehensive classification of food-energy-water nexus optimization studies: State of the art

    Martino, Marcello Di / Linke, Patrick / Pistikopoulos, Efstratios N.

    Journal of Cleaner Production. 2023 Aug. 03, p.138293-

    2023  , Page(s) 138293–

    Abstract: To tackle the globally increasing discrepancy between food, energy and water demands and resource availability sustainably, resource supply system models have to incorporate the inter-dependencies and -connectivities to other supply systems. This leads ... ...

    Abstract To tackle the globally increasing discrepancy between food, energy and water demands and resource availability sustainably, resource supply system models have to incorporate the inter-dependencies and -connectivities to other supply systems. This leads naturally to a food-energy-water nexus (FEWN) approach. The FEWN can be interpreted as the study of the connections between the food, energy and water resource systems, emphasizing how decision-making influences the synergies, conflicts and trade-offs among the various sectors. In recent years, modeling and optimization of FEWN systems has been receiving an increasing interest in the open literature, however, with limited emphasis on how decisions of the FEWN are derived. In this review, FEWN optimization studies are analyzed with focus on the employed objectives, optimization and solution strategies, as well as the selected sub-systems and their corresponding spatial and temporal scales to uncover in detail how decision-making is facilitated. More specifically, FEWN optimization studies are classified according to their modeling and solution strategies. Based on this classification it is uncovered that (i) the decision-making itself has not yet been investigated in detail in FEWN literature, (ii) the incorporation of all aspects of the FEWN is still a challenge, (iii) the interconnection between FEWN systems and society has to be further investigated, and (iv) the implications of uncertainty for the resiliency, robustness and security of process systems is not yet well defined. Additionally, a generic FEWN resource-task network formulation is introduced to illustrate the similarities across the various resource supply sectors. Special interest is placed on how synergies are identified and competition be avoided among resource systems. It is shown that the selected spatial scale as well as the utilized modeling and optimization strategies significantly influence the synergy level of obtained solutions. Furthermore, it is derived that the energy transition has to incorporate FEWN systems thinking for sustainable solution generation. Overall, this review summarizes the different applications and implications of process systems engineering concepts to FEWN systems.
    Keywords decision making ; energy ; society ; uncertainty ; Food-energy-water nexus ; Resource supply systems ; Process systems engineering ; Optimization ; Sustainability
    Language English
    Dates of publication 2023-0803
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2023.138293
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: A Neural Network Based Superstructure Optimization Approach to Reverse Osmosis Desalination Plants.

    Di Martino, Marcello / Avraamidou, Styliani / Pistikopoulos, Efstratios N

    Membranes

    2022  Volume 12, Issue 2

    Abstract: An ever-growing population together with globally depleting water resources pose immense stresses for water supply systems. Desalination technologies can reduce these stresses by generating fresh water from saline water sources. Reverse osmosis (RO), as ... ...

    Abstract An ever-growing population together with globally depleting water resources pose immense stresses for water supply systems. Desalination technologies can reduce these stresses by generating fresh water from saline water sources. Reverse osmosis (RO), as the industry leading desalination technology, typically involves a complex network of membrane modules that separate unwanted particles from water. The optimal design and operation of these complex RO systems can be computationally expensive. In this work, we present a modeling and optimization strategy for addressing the optimal operation of an industrial-scale RO plant. We employ a feed-forward artificial neural network (ANN) surrogate modeling representation with rectified linear units as activation functions to capture the membrane behavior accurately. Several ANN set-ups and surrogate models are presented and evaluated, based on collected data from the H2Oaks RO desalination plant in South-Central Texas. The developed ANN is then transformed into a mixed-integer linear programming formulation for the purpose of minimizing energy consumption while maximizing water utilization. Trade-offs between the two competing objectives are visualized in a Pareto front, where indirect savings can be uncovered by comparing energy consumption for an array of water recoveries and feed flows.
    Language English
    Publishing date 2022-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes12020199
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  7. Article ; Online: Systemic therapy with lenvatinib in advanced hepatocellular carcinoma: what to do in the case of a complete radiologic response?

    Pirozzi, Raffaele Emmanuele Maria / Di Martino, Marcello / Ferraro, Daniele / Pisaniello, Donatella / Vennarecci, Giovanni

    Journal of gastrointestinal and liver diseases : JGLD

    2023  Volume 32, Issue 1, Page(s) 118–119

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/drug therapy ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/drug therapy ; Phenylurea Compounds/therapeutic use ; Quinolines/therapeutic use
    Chemical Substances lenvatinib (EE083865G2) ; Phenylurea Compounds ; Quinolines
    Language English
    Publishing date 2023-04-01
    Publishing country Romania
    Document type Letter ; Comment
    ZDB-ID 2427021-0
    ISSN 1842-1121 ; 1841-8724
    ISSN (online) 1842-1121
    ISSN 1841-8724
    DOI 10.15403/jgld-4811
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    Zs.A 3825: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Correction: Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study.

    Pata, Francesco / Di Martino, Marcello / Podda, Mauro / Di Saverio, Salomone / Ielpo, Benedetto / Pellino, Gianluca

    World journal of surgery

    2022  Volume 47, Issue 1, Page(s) 285

    Language English
    Publishing date 2022-10-22
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-022-06808-2
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    Zs.A 1336: Show issues Location:
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  9. Article ; Online: Authors' Reply: Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study.

    Pata, Francesco / Di Martino, Marcello / Di Saverio, Salomone / Ielpo, Benedetto / Pellino, Gianluca

    World journal of surgery

    2022  Volume 47, Issue 1, Page(s) 283–284

    MeSH term(s) Humans ; COVID-19 ; Acute Disease ; Appendicitis/surgery
    Language English
    Publishing date 2022-10-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-022-06821-5
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  10. Article ; Online: Long-term experience with debulking surgery in extensive hepatic alveolar echinococcosis

    Mohsen Aliakbarian / Marcello Di Martino / Sara Saeidi

    Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 10, Pp 468-

    A case series and literature review

    2022  Volume 473

    Abstract: Objective: To assess the role of debulking surgery in extensive hepatic alveolar echinococcosis (HAE). Methods: Five cases of extensive HAE undergoing debulking surgery with their long-term follow-ups were reported. Additionally, a systematic review was ... ...

    Abstract Objective: To assess the role of debulking surgery in extensive hepatic alveolar echinococcosis (HAE). Methods: Five cases of extensive HAE undergoing debulking surgery with their long-term follow-ups were reported. Additionally, a systematic review was carried out. Results: The average age of patients in the study was (50.8±17.1) years (range 36 to 77 years). Three cases were female. The median follow-up period was 61 months (range 12 to 84 months). Left liver resections were performed in 2 cases and right hemihepatectomies were undertaken in 2 cases. Two patients (cases 2 and 4) developed early surgical complications, while one of them (case 4) who suffered from the recurrent sub-hepatic abscess died at 12 months postoperatively. Conclusions: This study highlights the importance of debulking surgery for the management of complex symptomatic HAE lesions in patients with no curative option available.
    Keywords alveolar echinococcosis ; debulking surgery ; reduction ; palliative ; echinoccocosis multilocularis ; case series ; Arctic medicine. Tropical medicine ; RC955-962
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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