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  1. Article ; Online: Classical complication of infective endocarditis: ruptured, large mycotic cerebral aneurysm.

    Chimparlee, Nitinan / Jittapiromsak, Pakrit / Tantivatana, Jarturon / Chattranukulchai, Pairoj

    BMJ case reports

    2014  Volume 2014

    MeSH term(s) Adolescent ; Aneurysm, Ruptured/diagnostic imaging ; Aneurysm, Ruptured/microbiology ; Basilar Artery ; Endocarditis, Subacute Bacterial/complications ; Endocarditis, Subacute Bacterial/diagnosis ; Female ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/microbiology ; Radiography ; Rupture, Spontaneous/diagnostic imaging ; Rupture, Spontaneous/microbiology ; Subarachnoid Hemorrhage/diagnostic imaging ; Subarachnoid Hemorrhage/microbiology
    Language English
    Publishing date 2014-03-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2013-202275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pyopneumopericardium and empyema thoracis from perforated oesophageal cancer.

    Chimparlee, Nitinan / Tumkosit, Monravee / Luengtaviboon, Kittichai / Chattranukulchai, Pairoj

    BMJ case reports

    2013  Volume 2013

    MeSH term(s) Aged ; Bacterial Infections/etiology ; Empyema, Pleural/etiology ; Esophageal Neoplasms/complications ; Esophageal Perforation ; Humans ; Male ; Pneumopericardium/diagnosis ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-07-02
    Publishing country England
    Document type Journal Article ; Case Reports
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2013-010053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical Characteristics of

    Chimparlee, Nitinan / Prechawat, Somchai / Khongphatthanayothin, Apichai / Mauleekoonphairoj, John / Lekchuensakul, Sarin / Wongcharoen, Wanwarang / Makarawate, Pattarapong / Sahasatas, Dujdao / Krittayaphong, Rungroj / Amnueypol, Montawatt / Anannab, Alisara / Ngarmukos, Tachapong / Vardhanabhuti, Saran / Sutjaporn, Boosamas / Wandee, Pharawee / Veerakul, Gumpanart / Bezzina, Connie R / Poovorawan, Yong / Nademanee, Koonlawee

    Circulation. Genomic and precision medicine

    2021  Volume 14, Issue 3, Page(s) e003229

    MeSH term(s) Adult ; Aged ; Amino Acid Substitution ; Brugada Syndrome/genetics ; Female ; Genetic Testing ; Humans ; Male ; Middle Aged ; Mutation, Missense ; NAV1.5 Voltage-Gated Sodium Channel/genetics ; Thailand
    Chemical Substances NAV1.5 Voltage-Gated Sodium Channel ; SCN5A protein, human
    Language English
    Publishing date 2021-06-07
    Publishing country United States
    Document type Clinical Trial ; Letter ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ISSN 2574-8300
    ISSN (online) 2574-8300
    DOI 10.1161/CIRCGEN.120.003229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Diagnostic and Prognostic Roles of Serum Osteopontin and Osteopontin Promoter Polymorphisms in Hepatitis B-related Hepatocellular Carcinoma.

    Chimparlee, Nitinan / Chuaypen, Natthaya / Khlaiphuengsin, Apichaya / Pinjaroen, Nutcha / Payungporn, Sunchai / Poovorawan, Yong / Tangkijvanich, Pisit

    Asian Pacific journal of cancer prevention : APJCP

    2015  Volume 16, Issue 16, Page(s) 7211–7217

    Abstract: Background: The aims of this study were to evaluate the diagnostic and prognostic roles of serum osteopontin (OPN) and single nucleotide polymorphisms (SNPs) in the OPN promoter in patients with hepatitis B-related hepatocellular carcinoma (HCC).: ... ...

    Abstract Background: The aims of this study were to evaluate the diagnostic and prognostic roles of serum osteopontin (OPN) and single nucleotide polymorphisms (SNPs) in the OPN promoter in patients with hepatitis B-related hepatocellular carcinoma (HCC).
    Materials and methods: Four groups were studied, which included 157 patients with HCC, 73 with liver cirrhosis (LC) and 97 with chronic hepatitis (CH), along with 80 healthy subjects. Serum OPN and alpha-fetoprotein (AFP) levels were measured. The SNPs -66 T/G, -156 G/δG and -433 C/T within the OPN promoter were determined by direct sequencing.
    Results: Serum OPN levels were significantly higher in patients with HCC than in the other groups. Area under receiver operating characteristics curves in distinguishing HCC from chronic liver disease (CLD; CH and LC) were 0.782 (95% CI; 0.729-0.834) for OPN and 0.888 (95% CI; 0.850-0.927) for AFP. Using the optimal cut-off value (70 ng/mL), OPN had sensitivity and specificity of 72% and 71%, respectively. Serum OPN was superior to AFP in detecting early-stage HCC (68% vs. 46%). A combination of both markers yielded an improved sensitivity for detecting early HCC to 82%. A high OPN level was significantly correlated with advanced BCLC stage and was an independent prognostic factor for HCC. The SNPs -156 and -443 were associated with susceptibility to HCC, but were not related to overall survival.
    Conclusions: Serum OPN is a useful diagnostic and prognostic marker for HCC. The combined use of serum OPN and AFP improved the diagnosis of early HCC. Genetic variation in the OPN promoter is associated with the risk, but not the prognosis of HCC.
    MeSH term(s) Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/blood ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/virology ; Case-Control Studies ; Female ; Follow-Up Studies ; Hepatitis B/blood ; Hepatitis B/genetics ; Hepatitis B/mortality ; Hepatitis B/virology ; Hepatitis B virus/genetics ; Humans ; Liver Neoplasms/blood ; Liver Neoplasms/genetics ; Liver Neoplasms/mortality ; Liver Neoplasms/virology ; Male ; Middle Aged ; Neoplasm Staging ; Osteopontin/blood ; Osteopontin/genetics ; Polymorphism, Genetic/genetics ; Prognosis ; Promoter Regions, Genetic/genetics ; ROC Curve ; Survival Rate ; alpha-Fetoproteins/analysis
    Chemical Substances Biomarkers, Tumor ; alpha-Fetoproteins ; Osteopontin (106441-73-0)
    Language English
    Publishing date 2015-10-29
    Publishing country Thailand
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2218955-5
    ISSN 2476-762X ; 1513-7368
    ISSN (online) 2476-762X
    ISSN 1513-7368
    DOI 10.7314/apjcp.2015.16.16.7211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hepatitis B and hepatitis C virus in Thai blood donors.

    Chimparlee, Nitinan / Oota, Sineenart / Phikulsod, Soisaang / Tangkijvanich, Pisit / Poovorawan, Yong

    The Southeast Asian journal of tropical medicine and public health

    2011  Volume 42, Issue 3, Page(s) 609–615

    Abstract: Hepatitis B virus (HBV) and hepatitis C virus (HCV) are major causes of transfusion-transmitted infection (TTI). In Thailand, the prevalence of HBV infection in new blood donors has decreased gradually from 7.1% in 1988 to 2.6% in 2009. This drastic ... ...

    Abstract Hepatitis B virus (HBV) and hepatitis C virus (HCV) are major causes of transfusion-transmitted infection (TTI). In Thailand, the prevalence of HBV infection in new blood donors has decreased gradually from 7.1% in 1988 to 2.6% in 2009. This drastic decline in HBV prevalence is mostly the result of an effective expanded program on immunization (EPI) against HBV; the current coverage rate with HBV vaccine in newborns is more than 98% nation-wide. The prevalence of HCV infection, has decreased at a slower rate due to lack of HCV vaccination. The use of healthy volunteer blood donors and nucleic acid amplification technology (NAT) has also contributed to the steady decrease in rates of HBV and HCV infections. We summarize the current status of the EPI program for preventing HBV and the current strategy of HBV and HCV screening in new blood donors.
    MeSH term(s) Adolescent ; Adult ; Aged ; Blood Donors ; Hepacivirus ; Hepatitis B/epidemiology ; Hepatitis B/prevention & control ; Hepatitis B Antigens/blood ; Hepatitis B Vaccines ; Hepatitis B virus/immunology ; Hepatitis C/epidemiology ; Hepatitis C/prevention & control ; Humans ; Mass Screening ; Middle Aged ; Thailand/epidemiology ; Young Adult
    Chemical Substances Hepatitis B Antigens ; Hepatitis B Vaccines
    Language English
    Publishing date 2011-05
    Publishing country Thailand
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 800646-5
    ISSN 0125-1562 ; 0038-3619
    ISSN 0125-1562 ; 0038-3619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Response of health care workers with isolated antibody to hepatitis B core antigen to hepatitis B vaccine.

    Chiarakul, Supawadee / Eunumjitkul, Krissana / Vorapimol, Ar-Reerat / Kaewkungwal, Jaranit / Chimparlee, Nitinan / Poovorawan, Yong

    The Southeast Asian journal of tropical medicine and public health

    2011  Volume 42, Issue 4, Page(s) 831–838

    Abstract: Isolated hepatitis B core antibody (antiHBc) without hepatitis B surface antigen (HBsAg) or hepatitis B surface antibody (antiHBs) is found during routine screening for hepatitis B virus (HBV) markers. Isolated antiHBc may indicate immunity against HBV ... ...

    Abstract Isolated hepatitis B core antibody (antiHBc) without hepatitis B surface antigen (HBsAg) or hepatitis B surface antibody (antiHBs) is found during routine screening for hepatitis B virus (HBV) markers. Isolated antiHBc may indicate immunity against HBV or occult infection. To determine the immune response of health care workers (HCWs) with isolated antiHBc, HCWs were divided into two groups. A single dose of recombinant hepatitis B (HB) vaccine was administered to HCWs with isolated antiHBc (n = 36) and healthy HCWs (n = 20) seronegative for HBsAg, antiHBc and antiHBs. One month later, the subjects were tested for antiHBs. Twenty-one of 36 HCW (58.3%) in the antiHBc group had antiHBs, while only 1 of 20 HCW (5.0%) in the seronegative control group had a detectable antiHBs titer exceeding 10 mIU/ml. The antiHBs response in HCWs with antiHBc was significantly higher than in the seronegative group. The subjects' sera were tested for HBV DNA by nested PCR. Of those with antiHBc, 4 had detectable HBV DNA (occult HBV infection). None of these 4 responded to the vaccine. Therefore, the response elicited by a single dose of HB vaccine administered to patients with antiHBc may serve as an indicator of occult HBV infection.
    MeSH term(s) Adult ; Antibody Formation ; Female ; Health Personnel ; Hepatitis B Antibodies/blood ; Hepatitis B Antibodies/immunology ; Hepatitis B Core Antigens/blood ; Hepatitis B Core Antigens/immunology ; Hepatitis B Surface Antigens/blood ; Hepatitis B Surface Antigens/immunology ; Hepatitis B Vaccines/immunology ; Humans ; Male
    Chemical Substances Hepatitis B Antibodies ; Hepatitis B Core Antigens ; Hepatitis B Surface Antigens ; Hepatitis B Vaccines
    Language English
    Publishing date 2011-07
    Publishing country Thailand
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 800646-5
    ISSN 0125-1562 ; 0038-3619
    ISSN 0125-1562 ; 0038-3619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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