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  1. Article ; Online: Optimization of beam dump shielding for K-130 cyclotron at VECC.

    Chatterjee, S / Banerjee, K / Pandit, Deepak / Roy, Pratap / Bandyopadhyay, T / Ravishankar, R / Bhattacharya, C / Bhattacharya, S / Datta, D / Banerjee, S R

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2017  Volume 128, Page(s) 216–223

    Abstract: A compact and efficient beam dump shield has been designed using Monte Carlo simulation code FLUKA to facilitate low background measurement of neutron and gamma rays using K130 cyclotron at Variable Energy Cyclotron Centre, Kolkata (VECC). Iron, lead and ...

    Abstract A compact and efficient beam dump shield has been designed using Monte Carlo simulation code FLUKA to facilitate low background measurement of neutron and gamma rays using K130 cyclotron at Variable Energy Cyclotron Centre, Kolkata (VECC). Iron, lead and high density Polyethylene (HDPE) were considered in the design of the beam dump shield. Representative FLUKA simulation results have been validated using in-beam experiment performed on the same beam dump constituents. Experimental neutron and gamma-rays energy spectra have been found to be in fair agreement with the simulation results. Activation of various beam dump shield components were also carried out.
    Language English
    Publishing date 2017-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2017.07.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mapping-free variant calling using haplotype reconstruction from k-mer frequencies.

    Audano, Peter A / Ravishankar, Shashidhar / Vannberg, Fredrik O

    Bioinformatics (Oxford, England)

    2017  Volume 34, Issue 10, Page(s) 1659–1665

    Abstract: ... We developed a novel k-mer algorithm and software implementation, Kestrel, capable of characterizing densely ... of a purely k-mer based approach affect overall sensitivity.: Availability and implementation: Source code ...

    Abstract Motivation: The standard protocol for detecting variation in DNA is to map millions of short sequence reads to a known reference and find loci that differ. While this approach works well, it cannot be applied where the sample contains dense variants or is too distant from known references. De novo assembly or hybrid methods can recover genomic variation, but the cost of computation is often much higher. We developed a novel k-mer algorithm and software implementation, Kestrel, capable of characterizing densely packed SNPs and large indels without mapping, assembly or de Bruijn graphs.
    Results: When applied to mosaic penicillin binding protein (PBP) genes in Streptococcus pneumoniae, we found near perfect concordance with assembled contigs at a fraction of the CPU time. Multilocus sequence typing (MLST) with this approach was able to bypass de novo assemblies. Kestrel has a very low false-positive rate when applied to the whole genome, and while Kestrel identified many variants missed by other methods, limitations of a purely k-mer based approach affect overall sensitivity.
    Availability and implementation: Source code and documentation for a Java implementation of Kestrel can be found at https://github.com/paudano/kestrel. All test code for this publication is located at https://github.com/paudano/kescases.
    Contact: paudano@gatech.edu or fredrik.vannberg@biology.gatech.edu.
    Supplementary information: Supplementary data are available at Bioinformatics online.
    MeSH term(s) Algorithms ; Genome, Bacterial ; Genomics/methods ; Haplotypes ; Multilocus Sequence Typing/methods ; Polymorphism, Genetic ; Software ; Streptococcus pneumoniae/genetics
    Language English
    Publishing date 2017-11-29
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1422668-6
    ISSN 1367-4811 ; 1367-4803
    ISSN (online) 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btx753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2374: Show issues Location:
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  3. Article: Mapping-free variant calling using haplotype reconstruction from k-mer frequencies

    Audano, Peter A / Ravishankar, Shashidhar / Vannberg, Fredrik O / Berger, Bonnie

    Bioinformatics. 2018 May 15, v. 34, no. 10

    2018  

    Abstract: ... a novel k-mer algorithm and software implementation, Kestrel, capable of characterizing densely packed ... identified many variants missed by other methods, limitations of a purely k-mer based approach affect overall ...

    Abstract The standard protocol for detecting variation in DNA is to map millions of short sequence reads to a known reference and find loci that differ. While this approach works well, it cannot be applied where the sample contains dense variants or is too distant from known references. De novo assembly or hybrid methods can recover genomic variation, but the cost of computation is often much higher. We developed a novel k-mer algorithm and software implementation, Kestrel, capable of characterizing densely packed SNPs and large indels without mapping, assembly or de Bruijn graphs. When applied to mosaic penicillin binding protein (PBP) genes in Streptococcus pneumoniae, we found near perfect concordance with assembled contigs at a fraction of the CPU time. Multilocus sequence typing (MLST) with this approach was able to bypass de novo assemblies. Kestrel has a very low false-positive rate when applied to the whole genome, and while Kestrel identified many variants missed by other methods, limitations of a purely k-mer based approach affect overall sensitivity. Source code and documentation for a Java implementation of Kestrel can be found at https://github.com/paudano/kestrel. All test code for this publication is located at https://github.com/paudano/kescases. Supplementary data are available at Bioinformatics online.
    Keywords DNA ; Streptococcus pneumoniae ; algorithms ; binding proteins ; bioinformatics ; computer software ; enzymes ; genes ; genetic variation ; graphs ; haplotypes ; loci ; multilocus sequence typing ; penicillins ; single nucleotide polymorphism
    Language English
    Dates of publication 2018-0515
    Size p. 1659-1665.
    Publishing place Oxford University Press
    Document type Article
    ZDB-ID 1468345-3
    ISSN 1460-2059 ; 1367-4811 ; 1367-4803
    ISSN (online) 1460-2059 ; 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btx753
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: MR image reconstruction from highly undersampled k-space data by dictionary learning.

    Ravishankar, Saiprasad / Bresler, Yoram

    IEEE transactions on medical imaging

    2011  Volume 30, Issue 5, Page(s) 1028–1041

    Abstract: ... reconstruction from undersampled k-space data. Recent CS methods have employed analytical sparsifying ... undersampled k-space data. The sparsity in this framework is enforced on overlapping image patches emphasizing ... and subsequently restores and fills-in the k-space data in the other step. Numerical experiments are ...

    Abstract Compressed sensing (CS) utilizes the sparsity of magnetic resonance (MR) images to enable accurate reconstruction from undersampled k-space data. Recent CS methods have employed analytical sparsifying transforms such as wavelets, curvelets, and finite differences. In this paper, we propose a novel framework for adaptively learning the sparsifying transform (dictionary), and reconstructing the image simultaneously from highly undersampled k-space data. The sparsity in this framework is enforced on overlapping image patches emphasizing local structure. Moreover, the dictionary is adapted to the particular image instance thereby favoring better sparsities and consequently much higher undersampling rates. The proposed alternating reconstruction algorithm learns the sparsifying dictionary, and uses it to remove aliasing and noise in one step, and subsequently restores and fills-in the k-space data in the other step. Numerical experiments are conducted on MR images and on real MR data of several anatomies with a variety of sampling schemes. The results demonstrate dramatic improvements on the order of 4-18 dB in reconstruction error and doubling of the acceptable undersampling factor using the proposed adaptive dictionary as compared to previous CS methods. These improvements persist over a wide range of practical data signal-to-noise ratios, without any parameter tuning.
    MeSH term(s) Algorithms ; Artificial Intelligence ; Brain/anatomy & histology ; Databases, Factual ; Humans ; Image Processing, Computer-Assisted/methods ; Lumbosacral Region/anatomy & histology ; Magnetic Resonance Imaging/methods ; Models, Theoretical
    Language English
    Publishing date 2011-05
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 622531-7
    ISSN 1558-254X ; 0278-0062
    ISSN (online) 1558-254X
    ISSN 0278-0062
    DOI 10.1109/TMI.2010.2090538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2546: Show issues Location:
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  5. Book: Migraine

    Ravishankar, K.

    (Journal of Association of Physicians of India ; 58,Apr., Suppl.)

    2010  

    Author's details guest ed. K. Ravishankar
    Series title Journal of Association of Physicians of India ; 58,Apr., Suppl.
    The Journal of the Association of Physicians of India
    Collection The Journal of the Association of Physicians of India
    Language English
    Size 36 S. : Ill.
    Publishing place Mumbai
    Publishing country India
    Document type Book
    HBZ-ID HT016388169
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs B 313 -58,Apr.,Suppl.- verfügbar in Königswinter Königswinter

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  6. Article ; Online: Uncommon (Group 4.0) Primary Headaches: Less Familiarity and More Missed Diagnosis.

    Ravishankar, Krishnamurthy

    Neurology India

    2021  Volume 69, Issue Supplement, Page(s) S168–S172

    Abstract: Background: Other primary headaches make up group 4.0 of the International Classification of Headache Disorders third edition (ICHD-3). This group includes a clinically varied group of headache entities whose pathophysiology is not well understood and ... ...

    Abstract Background: Other primary headaches make up group 4.0 of the International Classification of Headache Disorders third edition (ICHD-3). This group includes a clinically varied group of headache entities whose pathophysiology is not well understood and whose treatments are based on open-label reports.
    Objective: To review and update the uncommon primary headaches included under group 4.0 in ICHD-3.
    Methods: We reviewed the headache disorders listed under group 4.0 of ICHD-3 for the clinical features, diagnostic criteria, and management, and described recent updates of these relatively rare disorders.
    Results: The entities included in this group have a characteristic presentation in practice. Some of them are activity-related and can be provoked by Valsalva maneuver (primary cough headache), some by prolonged exercise (primary exercise headache), and some by sexual excitation (primary headache associated with sexual activity); primary thunderclap headache has also been included here because all the above-listed entities can sometimes present in thunderclap fashion too. Two of the entities in this group 4.0 are linked to direct physical stimuli viz. cold stimulus headache and external pressure headache. Also included in this group are primary stabbing headaches and nummular headaches that are presumed to be due to the involvement of the terminal branches of the sensory nerves supplying the scalp and are, therefore, termed "epicranial headaches." Hypnic headache syndrome and new daily persistent headache are included here as "miscellaneous headaches" because we still do not know enough about their causation.
    Conclusion: The headache disorders included under group 4.0 in ICHD-3 are uncommon, heterogeneous entities, which may pose diagnostic and management challenges to the physicians. The diagnosis may be missed owing to a lack of familiarity.
    MeSH term(s) Headache/diagnosis ; Headache/etiology ; Headache Disorders ; Headache Disorders, Primary/diagnosis ; Humans ; Missed Diagnosis ; Sexual Behavior
    Language English
    Publishing date 2021-05-18
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.315979
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    Zs.A 698: Show issues Location:
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  7. Article: ARCH Is Bringing Asia Closer to the Rest of the World.

    Wijeratne, Tissa / Ravishankar, Krishnamurthy

    Brain sciences

    2023  Volume 13, Issue 10

    Abstract: As the immediate Past President (KR) of Asian Regional Consortium For Headache (ARCH) and the newly appointed President (TW) of ARCH, we are pleased to share our thoughts with the readers of MDPI [ ... ]. ...

    Abstract As the immediate Past President (KR) of Asian Regional Consortium For Headache (ARCH) and the newly appointed President (TW) of ARCH, we are pleased to share our thoughts with the readers of MDPI [...].
    Language English
    Publishing date 2023-10-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13101430
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  8. Article: Classification of Trigeminal Autonomic Cephalalgia: What has Changed in International Classification of Headache Disorders-3 Beta?

    Ravishankar, K

    Annals of Indian Academy of Neurology

    2018  Volume 21, Issue Suppl 1, Page(s) S45–S50

    Abstract: The term "Trigeminal Autonomic Cephalalgia (TAC)" was first coined by Goadsby and Lipton[1] to include a group of relatively rare primary headache disorders characterized by moderate to severe, short-lived head pain in the trigeminal distribution with ... ...

    Abstract The term "Trigeminal Autonomic Cephalalgia (TAC)" was first coined by Goadsby and Lipton[1] to include a group of relatively rare primary headache disorders characterized by moderate to severe, short-lived head pain in the trigeminal distribution with unilateral cranial parasympathetic autonomic features, such as lacrimation, rhinorrhea, conjunctival injection, eyelid edema, and ptosis. In the current International Classification of Headache Disorders (ICHD-3 beta),[2] the TAC group includes cluster headache (CH), paroxysmal hemicrania (PH), short-lasting unilateral neuralgiform headache attacks (SUNHAs) and their 2 subforms - SUNHAs with conjunctival injection and tearing (SUNCT), SUNHAs with cranial autonomic symptoms (SUNA). Hemicrania Continua (HC) is also now included in the TAC group. Although the entities included under TACs seem broadly similar, they differ in attack duration, frequency and their response to different treatments. At one end of the spectrum lies CH, the prototypic TAC where the duration of attacks is the longest and at the other end is the SUNCT syndrome where the duration is shortest. There is some overlap across the entities; they are not difficult to recognize and subclassify. The umbrella term "TAC" for the short-lasting headaches with autonomic features was for the first time introduced in The ICHD, 2
    Language English
    Publishing date 2018-02-13
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_350_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Epitaxial Heterostructures of CsPbBr

    Patra, Avijit / Jagadish, Koushik / Ravishankar, N / Pradhan, Narayan

    Nano letters

    2024  Volume 24, Issue 5, Page(s) 1710–1716

    Abstract: The facet chemistry of halide perovskite nanocrystals plays a key role in designing nanoscale epitaxial heterostructures. However, despite significant successes achieved in designing these nanocrystals, their heterostructures with several leading ... ...

    Abstract The facet chemistry of halide perovskite nanocrystals plays a key role in designing nanoscale epitaxial heterostructures. However, despite significant successes achieved in designing these nanocrystals, their heterostructures with several leading transition metals could not be established yet. Herein, the possible heterostructures of metals beyond transition metals are explored and the epitaxial combinations of soft CsPbBr
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c04513
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  10. Article: Evaluation of

    Kori, V K / Ravishankar, B / Patel, K S

    Ayu

    2023  Volume 42, Issue 2, Page(s) 103–109

    Abstract: Background: Punarnavadi: Aim: To evaluate the hematinic effect of : Materials and methods: The test drug (: Results: Exposure of mercuric chloride to rats for 30 days resulted in a significant decrease of body weight, an increase in the weight ... ...

    Abstract Background: Punarnavadi
    Aim: To evaluate the hematinic effect of
    Materials and methods: The test drug (
    Results: Exposure of mercuric chloride to rats for 30 days resulted in a significant decrease of body weight, an increase in the weight of the liver and kidney and a decrease in hemoglobin content. It also decreased serum ferritin to a significant extent and increased serum TIBC. Histopathology of the liver shows macro fatty changes, vacuolization, marked necrosis, and severe degenerative changes, while the kidney shows cell infiltration. All these changes were significantly attenuated by the administration of
    Conclusion: The present data indicate that
    Language English
    Publishing date 2023-03-16
    Publishing country India
    Document type Journal Article
    ISSN 0974-8520
    ISSN 0974-8520
    DOI 10.4103/ayu.AYU_294_20
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