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  1. Article: Mindfulness-based Practices in Workers to Address Mental Health Conditions: A Systematic Review.

    Durand-Moreau, Quentin / Jackson, Tanya / Deibert, Danika / Els, Charl / Kung, Janice Y / Straube, Sebastian

    Safety and health at work

    2023  Volume 14, Issue 3, Page(s) 250–258

    Abstract: The effectiveness of mindfulness techniques in addressing mental health conditions in workers is uncertain. However, it could represent a therapeutic tool for workers presenting with such conditions. Our objective was to assess the effects of mindfulness- ...

    Abstract The effectiveness of mindfulness techniques in addressing mental health conditions in workers is uncertain. However, it could represent a therapeutic tool for workers presenting with such conditions. Our objective was to assess the effects of mindfulness-based practices for workers diagnosed with mental health conditions. We conducted a systematic review of randomized controlled trials. Participants included were workers with a mental health condition. Interventions included any mindfulness technique, compared to any nonmindfulness interventions. Outcomes were scores on validated psychiatric rating scales. A total of 4,407 records were screened; 202 were included for full-text analysis; 2 studies were included. The first study (Finnes et al., 2017) used Acceptance and Commitment Therapy (ACT) associated or not with Workplace Dialogue Intervention (WDI), compared to treatment as usual. At 9 months follow-up, for the ACT group, depression scores improved marginally (standardized mean difference [SMD]: -0.06,
    Language English
    Publishing date 2023-08-03
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2592798-X
    ISSN 2093-7997 ; 2093-7911
    ISSN (online) 2093-7997
    ISSN 2093-7911
    DOI 10.1016/j.shaw.2023.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An Update on Pediatric Environmental Health Specialty Units: Activities and Impacts, 2015-19.

    Woolf, Alan D / Jackson, J Elizabeth / Corcoran, Peter / Fritz, Meredith K / Kim, Stephani S / Maslak, Tanya M / Shah, Manthan / Hansen, Linda

    Academic pediatrics

    2024  

    Abstract: Objective: Pediatric Environmental Health Specialty Units (PEHSUs) address health concerns impacting children and their families related to environmental hazards by providing consultation and education to families, communities, and health care ... ...

    Abstract Objective: Pediatric Environmental Health Specialty Units (PEHSUs) address health concerns impacting children and their families related to environmental hazards by providing consultation and education to families, communities, and health care professionals. This analysis evaluated the productivity of the national PEHSU program.
    Methods: PEHSUs reported data on services provided to US communities between October 1, 2014 and September 30, 2019. Descriptive statistics and qualitative analysis are presented.
    Results: During this period, 6102 consultations and 4644 educational outreach activities were recorded. PEHSU faculty and staff published 462 articles, reviews, book chapters, fact sheets, commentaries, short informational pieces, and other materials between 2014 and 2019. These included 190 articles in scientific peer-reviewed journals and 29 textbook chapters to increase professional capacity in pediatric and reproductive environmental health. Lead, other metals, substances of abuse, pesticides, mold, and air pollution were frequently reported as agents of concern and educational topics. Requests for an overview of pediatric environmental health and outdoor pollutants were other frequently reported topics.
    Conclusions: PEHSUs work to decrease harmful exposures and improve children's health. They serve as expert resources for families, health care professionals, and communities on health effects related to environmental exposures. Data show the breadth and depth of concerns addressed and demonstrate the productivity and impact of this national program.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2483385-X
    ISSN 1876-2867 ; 1876-2859
    ISSN (online) 1876-2867
    ISSN 1876-2859
    DOI 10.1016/j.acap.2024.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mindfulness-based Practices in Workers to Address Mental Health Conditions

    Quentin Durand-Moreau / Tanya Jackson / Danika Deibert / Charl Els / Janice Y. Kung / Sebastian Straube

    Safety and Health at Work, Vol 14, Iss 3, Pp 250-

    A Systematic Review

    2023  Volume 258

    Abstract: The effectiveness of mindfulness techniques in addressing mental health conditions in workers is uncertain. However, it could represent a therapeutic tool for workers presenting with such conditions. Our objective was to assess the effects of mindfulness- ...

    Abstract The effectiveness of mindfulness techniques in addressing mental health conditions in workers is uncertain. However, it could represent a therapeutic tool for workers presenting with such conditions. Our objective was to assess the effects of mindfulness-based practices for workers diagnosed with mental health conditions. We conducted a systematic review of randomized controlled trials. Participants included were workers with a mental health condition. Interventions included any mindfulness technique, compared to any nonmindfulness interventions. Outcomes were scores on validated psychiatric rating scales. A total of 4,407 records were screened; 202 were included for full-text analysis; 2 studies were included. The first study (Finnes et al., 2017) used Acceptance and Commitment Therapy (ACT) associated or not with Workplace Dialogue Intervention (WDI), compared to treatment as usual. At 9 months follow-up, for the ACT group, depression scores improved marginally (standardized mean difference [SMD]: -0.06, p = 0.021), but anxiety scores were worse (SMD: 0.15, p = 0.036). Changes in mental health outcomes were not statistically significant for the ACT + WDI group. In the second study (Grensman et al., 2018), no statistically significant change in mental health scales has been observed after completion of mindfulness-based cognitive therapy compared to cognitive behavioral therapy. Substantial heterogeneity precluded meta-analysis. This systematic review did not find evidence that mindfulness-based practices provide a durable and substantial improvement of mental health outcomes in workers diagnosed with mental health conditions.
    Keywords Mental health ; Mindfulness ; Occupational groups ; Systematic review ; Public aspects of medicine ; RA1-1270
    Subject code 150
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Identifying prodromal symptoms at high specificity for Parkinson's disease.

    Jackson, Holly / Anzures-Cabrera, Judith / Simuni, Tanya / Postuma, Ronald B / Marek, Kenneth / Pagano, Gennaro

    Frontiers in aging neuroscience

    2023  Volume 15, Page(s) 1232387

    Abstract: Introduction: To test drugs with the potential to prevent the onset of Parkinson's disease (PD), it is key to identify individuals in the general population at high risk of developing PD. This is often difficult because most of the clinical markers are ... ...

    Abstract Introduction: To test drugs with the potential to prevent the onset of Parkinson's disease (PD), it is key to identify individuals in the general population at high risk of developing PD. This is often difficult because most of the clinical markers are non-specific, common in PD but also common in older adults (e.g., sleep problems).
    Objective: We aimed to identify the clinical markers at high specificity for developing PD by comparing individuals with PD or prodromal PD to healthy controls.
    Methods: We investigated motor and non-motor symptoms (Movement Disorder Society Unified Parkinson's Disease Rating Scale Part 1 and 2 items) in 64 prodromal PD and 422 PD individuals calculating the odds ratios, adjusting for age and gender, for PD and prodromal PD versus 195 healthy controls. Symptoms at high specificity were defined as having an adjusted odds ratio ≥ 6.
    Results: Constipation had an adjusted odds ratio, 6.14 [95% CI: 2.94-12.80] showing high specificity for prodromal PD, and speech difficulties had an adjusted odds ratio, 9.61 [95% CI: 7.88-48.81] showing high specificity for PD. The proportion of participants showing these specific markers was moderate (e.g., prevalence of constipation was 43.75% in prodromal PD, and speech difficulties was 33.89% in PD), suggesting these symptoms may make robust predictors of prodromal PD and PD, respectively.
    Discussion: Clinical markers at high specificity for developing PD could be used as tools in the screening of general populations to identify individuals at higher risk of developing PD.
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2023.1232387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Modulation of Trust in Borderline Personality Disorder by Script-Based Imaginal Exposure to Betrayal.

    Shapiro-Thompson, Rosa / Shah, Tanya V / Yi, Caroline / Jackson, Nasir / Trujillo Diaz, Daniel / Fineberg, Sarah K

    Journal of personality disorders

    2023  Volume 37, Issue 5, Page(s) 508–524

    Abstract: Interpersonal and trust-related difficulties are central features of borderline personality disorder (BPD). In this study, we applied script-driven betrayal imagery to evoke mistrustful behavior in a social reinforcement learning task. In 21 BPD and 20 ... ...

    Abstract Interpersonal and trust-related difficulties are central features of borderline personality disorder (BPD). In this study, we applied script-driven betrayal imagery to evoke mistrustful behavior in a social reinforcement learning task. In 21 BPD and 20 healthy control (HC) participants, we compared this approach to the standard confederate paradigm used in research studies. The script-driven imagery evoked a transient increase in negative affect and also decreased trusting behavior to a similar degree in both groups. Across conditions, we also replicated previously reported between-group differences in negative affect (increased in BPD) and task behavior (more sensitive to social cues in BPD). These results support the validity of script-driven imagery as an alternative social task stimulus. This script-driven imagery approach is appealing for clinical research studies on reinforcement learning because it eliminates deception, scales easily, and evokes disorder-specific states of social difficulty.
    MeSH term(s) Humans ; Trust ; Betrayal ; Borderline Personality Disorder
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639252-0
    ISSN 1943-2763 ; 0885-579X
    ISSN (online) 1943-2763
    ISSN 0885-579X
    DOI 10.1521/pedi.2023.37.5.508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The impact of steroid-sparing biologic therapies on weight loss in obese individuals with severe eosinophilic asthma.

    Nanzer, Alexandra M / Taylor, Victoria / Hearn, Andrew P / Kavanagh, Joanne E / Patrick, Tanya / Green, Linda / Thomson, Louise / Lam, Jodie / Fernandes, Mariana / Roxas, Cris / d'Ancona, Grainne / Kent, Brian D / Dhariwal, Jaideep / Jackson, David J

    The European respiratory journal

    2023  Volume 62, Issue 2

    MeSH term(s) Humans ; Asthma/complications ; Asthma/drug therapy ; Biological Therapy ; Steroids ; Obesity/complications ; Weight Loss
    Chemical Substances Steroids
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Letter
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00245-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Characteristics of operative pediatric trauma transfer patients.

    Lee, Su Yeon / Jackson, Jordan E / Vukcevich, Olivia / Stokes, Sarah C / Leshikar, Holly / Rinderknecht, Tanya / Kohler, Jonathan E / Brown, Erin G

    American journal of surgery

    2023  Volume 227, Page(s) 224–228

    Abstract: Background: Pediatric patients treated at trauma centers demonstrate improved outcomes, but investigation of optimal resource utilization surrounding the transfer is ongoing. We evaluated characteristics of operative pediatric trauma transfer patients ... ...

    Abstract Background: Pediatric patients treated at trauma centers demonstrate improved outcomes, but investigation of optimal resource utilization surrounding the transfer is ongoing. We evaluated characteristics of operative pediatric trauma transfer patients for resource optimization.
    Methods: A retrospective review of pediatric trauma patients transferred to a level 1 pediatric trauma center from 2009 to 2019 was performed. Patients were categorized by initial operative subspecialty.
    Results: Of 4164 transferred patients, 33.9 ​% required operative intervention. 65 ​% of operations were performed on orthopedic patients, who were significantly less injured compared to other patients. General surgery patients were more likely to undergo surgery on day of transfer compared to orthopedic patients (39.4%vs 56.3 ​%, OR 2.0, CI 1.4-2.8).
    Conclusions: One-third of pediatric trauma transfer patients required operative intervention. The majority of surgeries were on orthopedic patients, who were less likely to undergo surgery on day of transfer. Critical evaluation of this patient population is required to safely utilize a less resource-intensive transfer process.
    MeSH term(s) Humans ; Child ; Trauma Centers ; Retrospective Studies ; Surgical Wound ; Orthopedics ; Patient Transfer
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2023.09.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Social Media-Based Interventions for Health Behavior Change in Low- and Middle-Income Countries: Systematic Review.

    Seiler, Jessie / Libby, Tanya E / Jackson, Emahlea / Lingappa, J R / Evans, W D

    Journal of medical Internet research

    2022  Volume 24, Issue 4, Page(s) e31889

    Abstract: Background: Despite the wealth of evidence regarding effective health behavior change techniques using digital interventions to focus on residents of high-income countries, there is limited information of a similar nature for low- and middle-income ... ...

    Abstract Background: Despite the wealth of evidence regarding effective health behavior change techniques using digital interventions to focus on residents of high-income countries, there is limited information of a similar nature for low- and middle-income countries.
    Objective: The aim of this review is to identify and describe the available literature on effective social media-based behavior change interventions within low- and middle-income countries.
    Methods: This systematic review was conducted in accordance with the 2009 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We searched PubMed, Embase, Elsevier, CINAHL, PsycInfo, and Global Index Medicus, and the final search was conducted on April 6, 2021. We excluded studies published before 2000 because of the subject matter. We included studies that evaluated interventions conducted at least partly on a social media platform.
    Results: We identified 1832 studies, of which 108 (5.89%) passed title-abstract review and were evaluated by full-text review. In all, 30.6% (33/108) were included in the final analysis. Although 22 studies concluded that the social media intervention was effective, only 13 quantified the level of social media engagement, of which, few used theory (n=8) or a conceptual model (n=5) of behavior change.
    Conclusions: We identified gaps in the settings of interventions, types and sectors of interventions, length of follow-up, evaluation techniques, use of theoretical and conceptual models, and discussions of the privacy implications of social media use.
    Trial registration: PROSPERO CRD42020223572; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=223572.
    MeSH term(s) Developing Countries ; Health Behavior ; Humans ; Social Media
    Language English
    Publishing date 2022-04-14
    Publishing country Canada
    Document type Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/31889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of the COVID-19 booster vaccine on glycemia and insulin resistance in people with type 1 diabetes: A prospective pilot study.

    Zilbermint, Mihail / Motevalli, Mahsa / Batty, Kristine / Venner-Walcott, Jemila / Edwards, Alexis / Burley, Tanya / Jackson, Keith / Akhtar, Mehro / Demidowich, Andrew P

    Diabetes research and clinical practice

    2023  Volume 204, Page(s) 110898

    Abstract: Aims: Inflammation can trigger hyperglycemia in people with type 1 diabetes (T1D). Vaccines purposefully intend to cause an acute immunogenic response, and booster vaccines may cause even more potent immunologic responses. However, the effects of ... ...

    Abstract Aims: Inflammation can trigger hyperglycemia in people with type 1 diabetes (T1D). Vaccines purposefully intend to cause an acute immunogenic response, and booster vaccines may cause even more potent immunologic responses. However, the effects of vaccines on glycemic control and insulin requirements in the days immediately post-vaccination remains poorly understood. The aim of this study was to examine the changes in glycemic control and insulin usage immediately preceding and following a COVID-19 booster vaccine among adults with T1D.
    Methods: In this prospective cohort study of adults with T1D, participants wore blinded Dexcom G6 Pro continuous glucose monitors for 10 days. After a baseline period, participants received a COVID-19 booster vaccine, and subsequent changes in glycemic indices were evaluated.
    Results: Among the 21 enrolled participants, 38% received a Moderna and 62% Pfizer-BioNTech booster. Compared to baseline (162.9 ± 44.1 mg/dL), mean glucose was significantly increased at Day 2 (172.8 ± 47.0 mg/dL; p = 0.04) and Day 3 (173.1 ± 45.0 mg/dL; p = 0.02) post-vaccination. Insulin resistance was also increased on Day 2 (p = 0.03). There were no differences in outcome metrics between booster vaccine manufacturers.
    Conclusions: These results suggest that adults with type 1 diabetes may experience transient mild glycemic elevations after receiving a COVID-19 booster vaccination. Studies examining the effects of other vaccines are warranted.
    MeSH term(s) Adult ; Humans ; COVID-19 Vaccines/adverse effects ; Insulin Resistance ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Pilot Projects ; Prospective Studies ; COVID-19/prevention & control ; Insulin ; Insulin, Regular, Human ; Glucose
    Chemical Substances COVID-19 Vaccines ; Insulin ; Insulin, Regular, Human ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2023-09-09
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2023.110898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: High-dose opioids for chronic non-cancer pain: an overview of Cochrane Reviews.

    Els, Charl / Jackson, Tanya D / Hagtvedt, Reidar / Kunyk, Diane / Sonnenberg, Barend / Lappi, Vernon G / Straube, Sebastian

    The Cochrane database of systematic reviews

    2023  Volume 3, Page(s) CD012299

    Abstract: Background: This overview was originally published in 2017, and is being updated in 2022.  Chronic pain is typically described as pain on most days for at least three months. Chronic non-cancer pain (CNCP) is any chronic pain that is not due to a ... ...

    Abstract Background: This overview was originally published in 2017, and is being updated in 2022.  Chronic pain is typically described as pain on most days for at least three months. Chronic non-cancer pain (CNCP) is any chronic pain that is not due to a malignancy. Chronic non-cancer pain in adults is a common and complex clinical issue, for which opioids are prescribed by some physicians for pain management. There are concerns that the use of high doses of opioids for CNCP lacks evidence of effectiveness, and may increase the risk of adverse events.
    Objectives: To describe the evidence from Cochrane Reviews and overviews regarding the efficacy and safety of high-dose opioids (defined as 200 mg morphine equivalent or more per day) for CNCP.
    Methods: We identified Cochrane Reviews and overviews by searching the Cochrane Database of Systematic Reviews in The Cochrane Library. The date of the last search was 21 July 2022. Two overview authors independently assessed the search results. We planned to analyse data on any opioid agent used at a high dose for two weeks or more for the treatment of CNCP in adults.
    Main results: We did not identify any reviews or overviews that met the inclusion criteria. The excluded reviews largely reflected low doses or titrated doses, where all doses were analysed as a single group; we were unable to extract any data for high-dose use only.
    Authors' conclusions: There is a critical lack of high-quality evidence, in the form of Cochrane Reviews, about how well high-dose opioids work for the management of CNCP in adults, and regarding the presence and severity of adverse events.  No evidence-based argument can be made on the use of high-dose opioids, i.e. 200 mg morphine equivalent or more daily, in clinical practice. Considering that high-dose opioids have been, and are still being used in clinical practice to treat CNCP, knowing about the efficacy and safety of these higher doses is imperative.
    MeSH term(s) Adult ; Humans ; Analgesics, Opioid/adverse effects ; Chronic Pain/drug therapy ; Systematic Reviews as Topic ; Morphine/adverse effects ; Pain Management
    Chemical Substances Analgesics, Opioid ; Morphine (76I7G6D29C)
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 1469-493X
    ISSN (online) 1469-493X
    DOI 10.1002/14651858.CD012299.pub3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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