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Article ; Online: Determinants, Inequalities and Geographical Differences in Cognitive Performance Amongst the Elderly Population in South Korea

Sylvia Szabo / Malay Pramanik / Sayem Ahmed / Kevin Lesson

Asia Pacific Journal of Health Management (2023)

2023

Abstract: Using the most recent 2018 Korean Longitudinal Study of Aging (KLoSA) survey data, this study aimed to examine the key determinants of cognitive impairment (CI) and to explore the inequalities and geographic differences of CI amongst the South Korean ... ...

Abstract	Using the most recent 2018 Korean Longitudinal Study of Aging (KLoSA) survey data, this study aimed to examine the key determinants of cognitive impairment (CI) and to explore the inequalities and geographic differences of CI amongst the South Korean elderly population. The findings show that being super-aged, poor general health, and lack of exercise are positively associated with CI, while household wealth, educational level, participation in social activities and regular exercise all have a significant negative effect on CI. Compared to males, female respondents are more likely to experience CI. We found little difference between the specific determinates for the two subsamples. Inequalities in the prevalence of cognitive impairment were greatest in rural areas as well as amongst the respondents living in the Chungcheong region, Seoul Metropolitan Area and the Kangwan region. The results are helpful for the early intervention and prevention strategies to tackle the cognitive impairment problems of the elderly.
Keywords	cognitive impairment ; South Korea ; super-aged society ; socio-economic inequalities ; Medicine (General) ; R5-920 ; Public aspects of medicine ; RA1-1270
Subject code	950
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	ACHSM
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: In-silico whole-genome sequence analysis of a halotolerant filamentous mangrove cyanobacterium revealed CRISPR-Cas systems with unique properties.

Basu, Shayontani / Bhattacharya, Dhruba / Pramanik, Arnab / Saha, Malay / Mukherjee, Joydeep

Journal of phycology

2023 Volume 59, Issue 6, Page(s) 1339–1346

Abstract: Novel CRISPR systems capable of cleaving both DNA and RNA are progressively emerging as attractive tools for genome manipulation of prokaryotic and eukaryotic organisms. We report specific characteristics of CRISPR systems present in Oxynema aestuarii ... ...

Abstract	Novel CRISPR systems capable of cleaving both DNA and RNA are progressively emerging as attractive tools for genome manipulation of prokaryotic and eukaryotic organisms. We report specific characteristics of CRISPR systems present in Oxynema aestuarii AP17, a halotolerant, filamentous cyanobacterium and the second known member of the Oxynema genus. In-silico analyses of its whole-genome sequence revealed the presence of multiple Type I and Type III CRISPR loci with one Type I-G system previously unreported in cyanobacteria. We further identified the leader sequences at the 5' end of multiple CRISPR loci, many of which were distinct from previously reported cyanobacterial CRISPR leaders. Phylogenetic analyses of the O. aestuarii AP17 Cas1 proteins revealed two protein sequences that were unique and distantly related to other cyanobacterial Cas1 protein sequences. Our findings are significant because novel Class 1 CRISPR systems possess multi-subunit effectors and are highly flexible for repurposing by protein domain fusions made to the effector complex. Additionally, Type III CRISPRs are particularly useful for genome editing in certain extremophiles for which mesophilic Type II CRISPRs are ineffective.
MeSH term(s)	CRISPR-Cas Systems ; Phylogeny ; Cyanobacteria/genetics ; Genome ; Sequence Analysis
Language	English
Publishing date	2023-10-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	281226-5
ISSN	1529-8817 ; 0022-3646
ISSN (online)	1529-8817
ISSN	0022-3646
DOI	10.1111/jpy.13393
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Article ; Online: Hydrogeochemistry and quality evaluation of groundwater and its impact on human health in North Tripura, India.

Roy, Biplab / Pramanik, Malay / Manna, Ajay Kumar

Environmental monitoring and assessment

2022 Volume 195, Issue 1, Page(s) 39

Abstract: Groundwater contamination becomes an alarming threat to the provision of ecosystem services and natural resources. A very high level of groundwater contamination has been observed in the northeastern states particularly in North Tripura district. ... ...

Abstract	Groundwater contamination becomes an alarming threat to the provision of ecosystem services and natural resources. A very high level of groundwater contamination has been observed in the northeastern states particularly in North Tripura district. Therefore, the present study considered the region as a case study to evaluate the hydrogeochemical facies, heavy metal pollution and irrigation indices, and their impact on human health. For the investigation, we have collected a total of 35 groundwater samples from North Tripura district. Hydrogeochemical facies through Piper plot reflect Ca
MeSH term(s)	Child ; Adult ; Humans ; Water Quality ; Environmental Monitoring/methods ; Ecosystem ; Facies ; Water Pollutants, Chemical/analysis ; Groundwater/analysis ; Metals, Heavy/analysis ; Trace Elements/analysis ; Water/analysis ; India
Chemical Substances	Water Pollutants, Chemical ; Metals, Heavy ; Trace Elements ; Water (059QF0KO0R)
Language	English
Publishing date	2022-10-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-022-10642-3
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Article ; Online: Hydrogeochemistry and quality evaluation of groundwater and its impact on human health in North Tripura, India

Roy, Biplab / Pramanik, Malay / Manna, Ajay Kumar

Environ Monit Assess. 2023 Jan., v. 195, no. 1 p.39-39

2023

Abstract	Groundwater contamination becomes an alarming threat to the provision of ecosystem services and natural resources. A very high level of groundwater contamination has been observed in the northeastern states particularly in North Tripura district. Therefore, the present study considered the region as a case study to evaluate the hydrogeochemical facies, heavy metal pollution and irrigation indices, and their impact on human health. For the investigation, we have collected a total of 35 groundwater samples from North Tripura district. Hydrogeochemical facies through Piper plot reflect Ca²⁺–Mg²⁺–HCO₃⁻ and Na⁺–HCO₃⁻ as dominant water types. Gibbs plot identifies the dominance of rock-water interaction process in groundwater hydrochemistry. Geochemical plots indicate the dominance of silicate weathering, ion exchange and carbonate dissolution processes in groundwater mineralisation. The order of trace metal contaminations follows Fe > As > Zn > Mn > Cu > Pb. Results of heavy metal indices suggest above 80% samples are at high risk due to high Fe contamination. The risk of the heavy metal indices is associated with rising elevation in southern part of North Tripura. Findings of health risk assessment study imply that children face much carcinogenic and non-carcinogenic risks than adults because of unsafe levels of Fe and As. Multivariate statistical tools are applied to unravel interrelationships among all ions and trace metals as well as probable hydrogeochemical processes in groundwater. Results of Wilcox and USSL plots suggest 77% samples meet irrigation suitability criteria. Besides, the analysis suggests a better insight to identify hydrogeochemical processes controlling groundwater chemistry and the suitability of groundwater for irrigation and drinking purposes. The study also suggests treatment and sustainable management of groundwater resources is compulsory to reduce trace metal contaminations before public use.
Keywords	carbonates ; carcinogenicity ; case studies ; ecosystems ; face ; groundwater ; groundwater contamination ; health effects assessments ; heavy metals ; human health ; hydrogeochemistry ; ion exchange ; irrigation ; mineralization ; risk ; silicates ; trace elements ; India
Language	English
Dates of publication	2023-01
Size	p. 39.
Publishing place	Springer International Publishing
Document type	Article ; Online
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-022-10642-3
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Article ; Online: Identification of bio-climatic determinants and potential risk areas for Kyasanur forest disease in Southern India using MaxEnt modelling approach.

Pramanik, Malay / Singh, Poonam / Dhiman, Ramesh C

BMC infectious diseases

2021 Volume 21, Issue 1, Page(s) 1226

Abstract: Background: Kyasanur forest disease (KFD), known as monkey fever, was for the first time reported in 1957 from the Shivamogga district of Karnataka. But since 2011, it has been spreading to the neighbouring state of Kerala, Goa, Maharashtra, and Tamil ... ...

Abstract	Background: Kyasanur forest disease (KFD), known as monkey fever, was for the first time reported in 1957 from the Shivamogga district of Karnataka. But since 2011, it has been spreading to the neighbouring state of Kerala, Goa, Maharashtra, and Tamil Nadu. The disease is transmitted to humans, monkeys and by the infected bite of ticks Haemaphysalis spinigera. It is known that deforestation and ecological changes are the main reasons for KFD emergence, but the bio-climatic understanding and emerging pathways remain unknown. Methods: The present study aims to understand the bio-climatic determinants of distribution of tick vector of KFD in southern India using the Maximum Entropy (MaxEnt) model. The analysis was done using 34 locations of Haemaphysalis spinigera occurrence and nineteen bio-climatic variables from WorldClim. Climatic variables contribution was assessed using the Jackknife test and mean AUC 0.859, indicating the model performs with very high accuracy. Results: Most influential variables affecting the spatial distribution of Haemaphysalis spinigera were the average temperature of the warmest quarter (bio10, contributed 32.5%), average diurnal temperature range (bio2, contributed 21%), precipitation of wettest period (bio13, contributed 17.6%), and annual precipitation (bio12, contributed 11.1%). The highest probability of Haemaphysalis spinigera presence was found when the mean warmest quarter temperature ranged between 25.4 and 30 °C. The risk of availability of the tick increased noticeably when the mean diurnal temperature ranged between 8 and 10 °C. The tick also preferred habitat having an annual mean temperature (bio1) between 23 and 26.2 °C, mean temperature of the driest quarter (bio9) between 20 and 28 °C, and mean temperature of the wettest quarter (bio8) between 22.5 and 25 °C. Conclusions: The results have established the relationship between bioclimatic variables and KFD tick distribution and mapped the potential areas for KFD in adjacent areas wherein surveillance for the disease is warranted for early preparedness before the occurrence of outbreaks etc. The modelling approach helps link bio-climatic variables with the present and predicted distribution of Haemaphysalis spinigera tick.
MeSH term(s)	Animals ; Ecosystem ; Entropy ; India/epidemiology ; Ixodidae ; Kyasanur Forest Disease/epidemiology
Language	English
Publishing date	2021-12-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-021-06908-9
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Article: Improving outcomes for socioeconomic variables with coastal vulnerability index under significant sea-level rise: an approach from Mumbai coasts

Pramanik, Malay Kumar / Dash, Poli / Behal, Dimple

Environment, development and sustainability. 2021 Sept., v. 23, no. 9

2021

Abstract: Climate change has led to increased sea levels, which are caused by a complex interplay of the physical environment components from coastal areas, causing the rise in storm surge, erosion and flooding. In this scenario, the low-lying topography of the ... ...

Abstract	Climate change has led to increased sea levels, which are caused by a complex interplay of the physical environment components from coastal areas, causing the rise in storm surge, erosion and flooding. In this scenario, the low-lying topography of the Mumbai region is highly susceptible to sea level-induced flooding and coastal erosion due to the increasing number of economic activities. The unsustainable urbanization, unplanned development, and huge land conversion lead to the destruction of this region lead to the destruction of mangroves and filled waterways with construction debris which makes the region more vulnerable to flooding due to inadequate drainage, overflow and absence of natural protectors. These human-induced factors and their impacts remain unknown. Therefore, the study uses four socioeconomic variables (CVI4) with five geological (CVI5) and three geological variables (CVI8; with integrating CVI5) to assess the role of developmental and socio-economic activities in overall coastal vulnerability (CVI12) analysis. To quantify the importance of the combined variables and understand the response, random forest (RF) model was also used. This study selected four different iterations with integrating the pixel-based differentially weighted rank values of all variables to determine the significant causes behind that have an impact on coastal vulnerability index (CVI). The results show that CVI5 and CVI8 contributed 7.8% and 36.9%, respectively, whereas CVI4 contributed 55.3% to the CVI12. The response curve shows that the influence of these variables is an increasing trend to CVI12 and the results of CVI12 are highly correlated with socioeconomic index variables (r = 0.84, p = 0.001) which indicates the socio-economic variables played a major role towards the coastal vulnerability of the region. It suggests that unsustainable urbanization, unplanned development and coastal erosion increasing pressure make Mumbai and Kurla region more vulnerable to flood. Accordingly, CVI12 results show 55.83 km of the shoreline surveyed, being very low vulnerable, a moderate vulnerability of 60.91 km, while a high vulnerability of 50.75 km is considered to be very high. The results may be used as a guide in formulating policies to mitigate and adjust the Mumbai coast as the rise in sea level is expected to cause more frequent coastal floods, etc.
Keywords	climate change ; coasts ; drainage ; environment ; land use change ; models ; sea level ; shorelines ; storms ; topography ; urbanization ; India
Language	English
Dates of publication	2021-09
Size	p. 13819-13853.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1438730-x
ISSN	1387-585X
ISSN	1387-585X
DOI	10.1007/s10668-021-01239-w
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: In‐silico whole‐genome sequence analysis of a halotolerant filamentous mangrove cyanobacterium revealed CRISPR‐Cas systems with unique properties

Basu, Shayontani / Bhattacharya, Dhruba / Pramanik, Arnab / Saha, Malay / Mukherjee, Joydeep

Journal of Phycology. 2023 Dec., v. 59, no. 6 p.1339-1346

2023

Abstract	Novel CRISPR systems capable of cleaving both DNA and RNA are progressively emerging as attractive tools for genome manipulation of prokaryotic and eukaryotic organisms. We report specific characteristics of CRISPR systems present in Oxynema aestuarii AP17, a halotolerant, filamentous cyanobacterium and the second known member of the Oxynema genus. In‐silico analyses of its whole‐genome sequence revealed the presence of multiple Type I and Type III CRISPR loci with one Type I‐G system previously unreported in cyanobacteria. We further identified the leader sequences at the 5′ end of multiple CRISPR loci, many of which were distinct from previously reported cyanobacterial CRISPR leaders. Phylogenetic analyses of the O. aestuarii AP17 Cas1 proteins revealed two protein sequences that were unique and distantly related to other cyanobacterial Cas1 protein sequences. Our findings are significant because novel Class 1 CRISPR systems possess multi‐subunit effectors and are highly flexible for repurposing by protein domain fusions made to the effector complex. Additionally, Type III CRISPRs are particularly useful for genome editing in certain extremophiles for which mesophilic Type II CRISPRs are ineffective.
Keywords	CRISPR-Cas systems ; DNA ; RNA ; algology ; computer simulation ; extremophiles ; genome ; phylogeny ; protein domains ; salt tolerance ; sequence analysis
Language	English
Dates of publication	2023-12
Size	p. 1339-1346.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	281226-5
ISSN	1529-8817 ; 0022-3646
ISSN (online)	1529-8817
ISSN	0022-3646
DOI	10.1111/jpy.13393
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Geospatial multi-criteria evaluation to identify groundwater potential in a Himalayan District, Rudraprayag, India

Kumar, Atul / Pramanik, Malay / Chaudhary, Shairy / Negi, Mahabir Singh / Szabo, Sylvia

Environ Dev Sustain. 2023 Feb., v. 25, no. 2 p.1519-1560

2023

Abstract: The Himalayan region faces significant challenges in groundwater resource management due to the relief, precipitous slope, and rocky surface, leading to a lower infiltration into subsurface groundwater. Moreover, the region faces significant challenges ... ...

Abstract	The Himalayan region faces significant challenges in groundwater resource management due to the relief, precipitous slope, and rocky surface, leading to a lower infiltration into subsurface groundwater. Moreover, the region faces significant challenges due to the decline in its quantity and deterioration in quality, exacerbated by urbanisation, land-use change, over-abstraction, poor administration, and mismanagement. Therefore, the present study adopted the Analytic Hierarchy Process (AHP) and geospatial techniques to identify groundwater potential sites in the Rudraprayag district, the Indian Himalayan Region. We used expert knowledge to assign weights, then normalised by AHP eigenvector. The final index was developed using the weighted overlay method and specific criteria, including geomorphology, geology, slope, relief, drainage density, lineament density, dissection index, precipitation, and land use/land cover (LULC). We used the receiver operating characteristic (ROC) curve and the estimated area under the curve (AUC) for validation. The groundwater potential results show that the very few areas are potentially good (1.4%, 26.81 km²) and moderately good (17.70%, 350.9 km²), while 61.35% (1216.61 km²) areas are moderate to poor groundwater potential. The results show that plain to the nearly plain surface of the valley floor and the vicinity of perennial river (Alaknanda and Mandakini River valleys) areas are most potentially best sites for groundwater development. The groundwater potential sites proposed in the study can help farmers, regional planners, and local governments make more precise decisions to determine the groundwater development sites for installing hand pumps and tube wells for regular water supply. The study results have implications for developing a sustainable groundwater management plan to reduce the risk of water scarcity, improve the efficiency of water use, and restore and protect water-related ecosystems in the region.
Keywords	dissection ; drainage ; expert opinion ; geomorphology ; groundwater ; land cover ; land use change ; resource management ; risk reduction ; rivers ; urbanization ; water management ; water shortages ; water use efficiency ; Himalayan region ; India
Language	English
Dates of publication	2023-02
Size	p. 1519-1560.
Publishing place	Springer Netherlands
Document type	Article ; Online
ZDB-ID	1438730-x
ISSN	1387-585X
ISSN	1387-585X
DOI	10.1007/s10668-021-02107-3
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Article: Population health risks in multi-hazard environments: action needed in the Cyclone Amphan and COVID-19 – hit Sundarbans region, India

Pramanik, Malay / Szabo, Sylvia / Pal, Indrajit / Udmale, Parmeshwar / Pongsiri, Montira / Chilton, Susan

Climate and development. 2022 Feb. 07, v. 14, no. 2

2022

Abstract: The local population of Sundarbans, an environmentally vulnerable delta region in south-eastern India, is currently affected by combined negative impacts of cyclone Amphan and the COVID-19 pandemic. The lockdown measures have created an additional burden ...

Abstract	The local population of Sundarbans, an environmentally vulnerable delta region in south-eastern India, is currently affected by combined negative impacts of cyclone Amphan and the COVID-19 pandemic. The lockdown measures have created an additional burden on the health care system, while flooding during Amphan increased the risk of spreading water-borne diseases. In this viewpoint, we provide a conceptual model of the complex interlinkages among the combined multi-hazard effects, human health and water availability, with possible mitigation measures. We then discuss the specific pathways through which these immediate and long-term impacts occur and highlight the risk of together slowing progress on SDG3 and SDG6 in the Sundarbans. Finally, we call for coordinated assessment, support and appropriate intervention measures to secure clean water availability and minimize the health impacts of the recent multiple disasters in this tropical delta region.
Keywords	COVID-19 infection ; climate ; health services ; human health ; models ; risk ; India
Language	English
Dates of publication	2022-0207
Size	p. 99-104.
Publishing place	Taylor & Francis
Document type	Article
ISSN	1756-5537
DOI	10.1080/17565529.2021.1889948
Database	NAL-Catalogue (AGRICOLA)

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Article: Impacts of predicted sea level rise on land use/land cover categories of the adjacent coastal areas of Mumbai megacity, India

Pramanik, Malay Kumar

Environment, development and sustainability. 2017 Aug., v. 19, no. 4

2017

Abstract: Physical and ecological responses of the coastal areas in the vicinity of Mumbai, India, due to relative sea level rise are examined by different inundation scenarios. Evaluation of potential habitat loss under sea level rise was made by incorporating ... ...

Abstract	Physical and ecological responses of the coastal areas in the vicinity of Mumbai, India, due to relative sea level rise are examined by different inundation scenarios. Evaluation of potential habitat loss under sea level rise was made by incorporating the land use/land cover (LULC) adopted from the digital elevation model with the satellite imagery. LULC categories overlaid on 1.0, 2.0, 3.0 and 4.0 m coastal elevation showed that the coastal areas of Mumbai were mostly covered by vegetation followed by barren land, agricultural land, urban areas and water bodies. For the relative sea level rise scenarios of 1.0, 2.0, 3.0 and 4.0Â m, the tidal inundation areas were estimated to be 257.85, 385.58, 487.56 and 570.63Â kmÂ², respectively, using GIS techniques. The losses of urban areas were also estimated at 25.32, 41.64, 54.61 and 78.86Â kmÂ² for the 1.0, 2.0, 3.0 and 4.0 m relative sea level rise, respectively, which is most alarming information for the most populated city on the eastern coast of India. The results conclude that relative sea level rise scenario will lead profound impacts on LULC categories as well as on coastal features and landforms in the adjoining part of Mumbai. The sea level rise would also reduce the drainage gradients that promote flooding condition to rainstorms and subsequently increase saltwater intrusion into coastal regions. Alterations in the coastal features and landforms correlated with inundation characteristics that make the coastal region more vulnerable in the coming decades due to huge development activities and population pressures in Mumbai.
Keywords	agricultural land ; coasts ; digital elevation models ; drainage ; flooded conditions ; geographic information systems ; habitat destruction ; land cover ; land use ; remote sensing ; saltwater intrusion ; sea level ; surface water ; urban areas ; vegetation ; India
Language	English
Dates of publication	2017-08
Size	p. 1343-1366.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1438730-x
ISSN	1387-585X
ISSN	1387-585X
DOI	10.1007/s10668-016-9804-9
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