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  1. Article ; Online: The effect of Ding-kun-dan comparing with Marvelon on primary dysmenorrhea: A prospective, double-blind, multicenter, randomized controlled trial.

    Gan, Jingwen / Zhu, Shi-Yang / Ma, Xiao / Ding, Xue-Song / Deng, Yan / Wang, Yanfang / Sun, Ai-Jun

    Journal of ethnopharmacology

    2023  Volume 318, Issue Pt B, Page(s) 116975

    Abstract: Ethnopharmacological relevance: Ding-kun-dan (DKD), as one of well-known ... Aim of the study: To compare the effect of Ding-kun-dan (DKD) with Marvelon on relief of symptoms and ... 4: Conclusion: Ding-kun-dan is another available, effective and safe method for patients ...

    Abstract Ethnopharmacological relevance: Ding-kun-dan (DKD), as one of well-known traditional Chinese medicine (TCM), is considered as an effective prescription to regulate menstruation, benefit Qi and nourish the blood. Previous studies had showed that DKD could improve sex hormone levels, insulin resistance, metabolism abnormalities and regulate immunity in animal models with polycystic ovary syndrome or endometriosis, however, little study conducted to reveal its clinical efficacy in Primary Dysmenorrhea (PD).
    Aim of the study: To compare the effect of Ding-kun-dan (DKD) with Marvelon on relief of symptoms and change of serum pain-related factors in patients with primary dysmenorrhea.
    Materials and method: 136 patients with primary dysmenorrhea were randomly assigned to the DKD group (n = 73, take one tablet per day from 5th day of the menstrual cycle for 10 days every 28 days) and the Marvelon group (n = 63, take one tablet per day from 5th day of the menstrual cycle for 21 days every 28 days), the therapeutic effects were analyzed through evaluating the change of VAS scores, CMSS scores and the level of PGF
    Results: Both DKD and Marvelon could effectively relief pain and other associated symptoms at each visit (Baseline, 4
    Conclusion: Ding-kun-dan is another available, effective and safe method for patients with primary dysmenorrhea to choose, especially for those who are suffered from mild pain and/or contraindicated to hormonal agents.
    MeSH term(s) Female ; Humans ; Desogestrel/therapeutic use ; Dinoprostone ; Double-Blind Method ; Dysmenorrhea/drug therapy ; Dysmenorrhea/diagnosis ; Endometriosis ; Medicine, Chinese Traditional ; Prospective Studies
    Chemical Substances Desogestrel (81K9V7M3A3) ; Dinoprostone (K7Q1JQR04M)
    Language English
    Publishing date 2023-07-29
    Publishing country Ireland
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The effect of Ding-kun-dan comparing with Marvelon on primary dysmenorrhea: A prospective, double-blind, multicenter, randomized controlled trial

    Gan, Jingwen / Zhu, Shi-yang / Ma, Xiao / Ding, Xue-song / Deng, Yan / Wang, Yanfang / Sun, Ai-jun

    Journal of Ethnopharmacology. 2024 Jan., v. 318 p.116975-

    2024  

    Abstract: Ding-kun-dan (DKD), as one of well-known traditional Chinese medicine (TCM), is considered ... conducted to reveal its clinical efficacy in Primary Dysmenorrhea (PD). To compare the effect of Ding-kun ... and NO between DKD and Marvelon group at each follow-up. No serious adverse effect was observed. Ding ...

    Abstract Ding-kun-dan (DKD), as one of well-known traditional Chinese medicine (TCM), is considered as an effective prescription to regulate menstruation, benefit Qi and nourish the blood. Previous studies had showed that DKD could improve sex hormone levels, insulin resistance, metabolism abnormalities and regulate immunity in animal models with polycystic ovary syndrome or endometriosis, however, little study conducted to reveal its clinical efficacy in Primary Dysmenorrhea (PD). To compare the effect of Ding-kun-dan (DKD) with Marvelon on relief of symptoms and change of serum pain-related factors in patients with primary dysmenorrhea. 136 patients with primary dysmenorrhea were randomly assigned to the DKD group (n = 73, take one tablet per day from 5th day of the menstrual cycle for 10 days every 28 days) and the Marvelon group (n = 63, take one tablet per day from 5th day of the menstrual cycle for 21 days every 28 days), the therapeutic effects were analyzed through evaluating the change of VAS scores, CMSS scores and the level of PGF₂ₐ, PGE₂, PGF₂ₐ/PGE₂ and NO during the 12 weeks intervention. Both DKD and Marvelon could effectively relief pain and other associated symptoms at each visit (Baseline, 4ᵗʰ week, 8ᵗʰ week and 12ᵗʰ week). Although Marvelon was significantly superior to DKD in reducing VAS scores, the total CMSS, CMSS severity and duration scores at each posttreatment follow-up (P < 0.01), VAS scores in the DKD group decreased significantly over time while scores in the COC group only dropped rapidly after the first two months of treatment. Efficacy gap between two interventions continuously narrowed over time and the efficacy of DKD became non-inferior at the 12ᵗʰ week compared to that of Marvelon (the difference between groups, – 0.78%; 95% confidence interval (CI), −13.67%–12.75%; non-inferiority margin, 15%). DKD group had better efficacy on mild pain compared to that of the COC group with no statistical difference (75% VS 61.9%, P > 0.05). DKD and Marvelon could effectively reduce PGF₂ₐ, PGE₂ and higher PGF₂ₐ/PGE₂ in patients with PD. There was no statistical difference in the level of PGF₂ₐ, PGE₂, PGF₂ₐ/PGE₂ and NO between DKD and Marvelon group at each follow-up. No serious adverse effect was observed. Ding-kun-dan is another available, effective and safe method for patients with primary dysmenorrhea to choose, especially for those who are suffered from mild pain and/or contraindicated to hormonal agents.
    Keywords Oriental traditional medicine ; adverse effects ; animals ; blood serum ; confidence interval ; endometriosis ; immunity ; insulin resistance ; menstruation ; metabolism ; pain ; polycystic ovary syndrome ; therapeutics ; Primary dysmenorrhea ; Ding-kun-dan ; Marvelon ; VAS ; CMSS ; PGF2a ; PGE2 ; PGF2a/PGE2
    Language English
    Dates of publication 2024-01
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116975
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Experience of Dr. Ding Guangdi in treating chronic enteritis.

    Shi, Yiping

    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

    2007  Volume 27, Issue 2, Page(s) 128–130

    MeSH term(s) Adult ; China ; Chronic Disease/therapy ; Drugs, Chinese Herbal/therapeutic use ; Enteritis/drug therapy ; History, 20th Century ; History, 21st Century ; Humans ; Male ; Medicine, Chinese Traditional/history
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2007-06
    Publishing country China
    Document type Case Reports ; Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603186-9
    ISSN 0254-6272 ; 0255-2922
    ISSN (online) 0254-6272
    ISSN 0255-2922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Yun yu ding cheng zhai ri ji

    Yun, Yuding / Shi, Xiaofeng

    (Guo jia qing shi bian zuan wei yuan hui wen xian cong kan ; 国家清史编纂委员会文献丛刊)

    2004  

    Author's details Yun yu ding zhu, shi xiao feng zheng li
    Series title Guo jia qing shi bian zuan wei yuan hui wen xian cong kan
    国家清史编纂委员会文献丛刊
    Language Chinese
    Size 3, 3, 2, 417 S
    Publisher Zhe jiang gu ji chu ban she
    Publishing place Hang zhou
    Document type Book
    ISBN 7805189447 ; 9787805189444
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book: Yun yu ding cheng zhai ri ji

    Yun, Yuding / Shi, Xiaofeng

    (Guo jia qing shi bian zuan wei yuan hui wen xian cong kan ; 国家清史编纂委员会文献丛刊)

    2004  

    Author's details Yun yu ding zhu, shi xiao feng zheng li
    Series title Guo jia qing shi bian zuan wei yuan hui wen xian cong kan
    国家清史编纂委员会文献丛刊
    Language Chinese
    Size S.417-812
    Publisher Zhe jiang gu ji chu ban she
    Publishing place Hang zhou
    Document type Book
    ISBN 7805189447 ; 9787805189444
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Yun yu ding cheng zhai ri ji

    Yun, Yuding / Shi, Xiaofeng

    (Guo jia qing shi bian zuan wei yuan hui wen xian cong kan ; 国家清史编纂委员会文献丛刊)

    2004  

    Author's details Yun yu ding zhu, shi xiao feng zheng li
    Series title Guo jia qing shi bian zuan wei yuan hui wen xian cong kan
    国家清史编纂委员会文献丛刊
    Language Chinese
    Size 2 v.
    Publisher Zhe jiang gu ji chu ban she
    Publishing place Hang zhou
    Document type Book
    ISBN 7805189447 ; 9787805189444
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book: Song Yuan ci qi jian ding er shi jiang

    Shi, Shuqing

    (Jian bao dazhong shoucang congshu; 7 ; 鉴宝大众收藏丛书 ; 7)

    2007  

    Author's details Shi Shuqing zhubian
    Series title Jian bao dazhong shoucang congshu; 7
    鉴宝大众收藏丛书 ; 7
    Language Chinese
    Size 191 p, Ill
    Edition Di 1 ban
    Publisher Jilin chuban jituan
    Publishing place Changchun
    Document type Book
    ISBN 9787807206200 ; 7807206209
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book: Bei tie jian ding

    Ma, Ziyun / Shi, Anchang

    Appraisal of rubbings from stone inscription

    ("Zhongguo wen wu jian ding" cong shu)

    1993  

    Title variant Appraisal of rubbings from stone inscriptions
    Author's details Ma zi yun; shi an chang zhu
    Series title "Zhongguo wen wu jian ding" cong shu
    Keywords Calligraphy, Chinese/Catalogs ; Rubbing/Catalogs
    Language Chinese
    Size 5, 81, 484 p, ill, 21 cm
    Edition Di 1 ban
    Publisher Guang xi shi fan da xue chu ban she
    Publishing place Gui lin
    Document type Book
    ISBN 7563316922 ; 9787563316922
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article: [Screening genes related to 'black' character in wu-ding chicken by delta differential display].

    Wu, Ge-Min / Liu, Xiao-Chun / Lou, Yi-Zhou / Shi, Qi-Shun

    Yi chuan xue bao = Acta genetica Sinica

    2005  Volume 32, Issue 1, Page(s) 30–37

    Abstract: The 'black' character is a cardinal character of black chicken that is very important to the medical value and economical value of black chicken. The study compared gene expression between black chicken and non-black chicken by delta differential display ...

    Abstract The 'black' character is a cardinal character of black chicken that is very important to the medical value and economical value of black chicken. The study compared gene expression between black chicken and non-black chicken by delta differential display method, and obtained twenty-nine expressed sequence tags(ESTs) by extraction, amplification, purification, northern blotting, cloning and sequencing of gel-embedded DNA. Of twenty-nine ESTs, eight ESTs have high similarity rate with known gene in chicken-beta-trepomyosin gene, cardiac myosin alkali light chain gene, insertionally activated c-Ha-ras oncogene, fra-2 oncogene, 16S rRNA gene and mitochondrion genome sequence, respectively, with similarity rate 97%,100%, 98%, 98%, 98%, 99%, 99% and 97%. Five ESTs have high similarity rate with human TTN gene, human phosphoglucomutase 5 gene, human or mouse signal recongnition particle 54 kD gene, human or mouse ribonuclease/angiogenin inhibitor gene, respectively, with similarity rate 82%, 82%, 87%, 99% and 99%. Their homologous genes in chicken are still not cloned. Thirteen ESTs are novel gene fragments. Of thirteen ESTs, nine ESTs have high similarity with ESTs in database. Four ESTs have not high similarity with any EST in database. The results of gene expression analysis show that one known gene (insertionally activated c-Ha-ras oncogene) fragment and one novel gene fragment are expressed in all non-black chicken and are not expressed in all black chicken, and that one known gene (signal recongnition particle 54 kD gene) fragment is expressed in all black chicken and is not expressed in all non-black chicken. According to these results, we conclude that the expression of insertionally activated c-Ha-ras oncogene, signal recongnition particle 54 kD gene and one novel gene are related to the 'black' character in chicken.
    MeSH term(s) Animals ; Chickens/genetics ; Chickens/metabolism ; Expressed Sequence Tags ; Gene Expression Profiling ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Recognition Particle/metabolism
    Chemical Substances SRP54 protein, human ; Signal Recognition Particle
    Language Chinese
    Publishing date 2005-01
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 190603-3
    ISSN 0379-4172
    ISSN 0379-4172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Conference proceedings: Boron in plant physiology and nutrition

    White, Philip J. / Ding, Guangda / Shi, Lei / Xu, Fangsen

    paper presented to the International Fertiliser Society at a conference in Cambridge, UK, on 10th December 2021

    (Proceedings / International Fertiliser Society ; 859)

    2021  

    Author's details by Philip J. White, Guangda Ding, Lei Shi and Fangsen Xu
    Series title Proceedings / International Fertiliser Society ; 859
    Proceedings / the International Fertiliser Society
    Collection Proceedings / the International Fertiliser Society
    Language English
    Size 40 Seiten, Diagramme
    Publisher International Fertiliser Society
    Publishing place Colchester
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    Note Literaturverzeichnis: Seite 26-38
    HBZ-ID HT021213883
    ISBN 978-0-85310-496-4 ; 0-85310-496-4
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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