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  1. Article ; Online: Rotary F

    Li, Yue / Liu, Jun / Wu, Yingjie / He, Qiang

    Journal of the American Chemical Society

    2024  

    Abstract: We report the hierarchical assembly of a chloroplast-derived rotary ... ...

    Abstract We report the hierarchical assembly of a chloroplast-derived rotary F
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c00334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
    Z 7.3: Show issues

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  2. Article ; Online: Plasmonic silver and gold nanoparticles: shape- and structure-modulated plasmonic functionality for point-of-caring sensing, bio-imaging and medical therapy.

    Hang, Yingjie / Wang, Anyang / Wu, Nianqiang

    Chemical Society reviews

    2024  Volume 53, Issue 6, Page(s) 2932–2971

    Abstract: Silver and gold nanoparticles have found extensive biomedical applications due to their strong localized surface plasmon resonance (LSPR) and intriguing plasmonic properties. This review article focuses on the correlation among particle geometry, plasmon ...

    Abstract Silver and gold nanoparticles have found extensive biomedical applications due to their strong localized surface plasmon resonance (LSPR) and intriguing plasmonic properties. This review article focuses on the correlation among particle geometry, plasmon properties and biomedical applications. It discusses how particle shape and size are tailored
    MeSH term(s) Gold/chemistry ; Silver/chemistry ; Metal Nanoparticles/chemistry ; Surface Plasmon Resonance/methods ; Spectrum Analysis, Raman/methods
    Chemical Substances Gold (7440-57-5) ; Silver (3M4G523W1G)
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1472875-8
    ISSN 1460-4744 ; 0306-0012
    ISSN (online) 1460-4744
    ISSN 0306-0012
    DOI 10.1039/d3cs00793f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Macrocycle-Based Hierarchically Porous Hydrogen-Bonded Organic Frameworks.

    Wang, Hui / Wang, Danbo / Wu, Yumin / Zhao, Yingjie

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2024  Volume 30, Issue 14, Page(s) e202303618

    Abstract: Hydrogen-bonded organic frameworks (HOFs) are porous crystalline materials. The pores in HOFs are usually non-covalent extrinsic pores constructed through the formation of the framework. Supramolecular macrocycles with intrinsic pores in their structures ...

    Abstract Hydrogen-bonded organic frameworks (HOFs) are porous crystalline materials. The pores in HOFs are usually non-covalent extrinsic pores constructed through the formation of the framework. Supramolecular macrocycles with intrinsic pores in their structures are good candidates for constructing HOFs with intrinsic pores from the macrocycles themselves, thus leading to hierarchically porous structures. Combining the macrocycle and HOFs will endow these hierarchically porous materials with enhanced properties and special functionalities. This review summarizes recent advances in macrocycle-based HOFs, including the macrocycles used for constructing HOFs, the hierarchically porous structures of the HOFs, and the applications induced by the hierarchically HOFs porous structures. This review provides insights for future research on macrocycle-based hierarchically porous HOFs and the appropriate applications of the unique structures.
    Language English
    Publishing date 2024-01-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202303618
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  4. Article ; Online: Recent advances in targeted drug delivery for the treatment of glioblastoma.

    Mao, Meng / Wu, Yingjie / He, Qiang

    Nanoscale

    2024  

    Abstract: Glioblastoma multiforme (GBM) is one of the highly malignant brain tumors characterized by significant morbidity and mortality. Despite the recent advancements in the treatment of GBM, major challenges persist in achieving controlled drug delivery to ... ...

    Abstract Glioblastoma multiforme (GBM) is one of the highly malignant brain tumors characterized by significant morbidity and mortality. Despite the recent advancements in the treatment of GBM, major challenges persist in achieving controlled drug delivery to tumors. The management of GBM poses considerable difficulties primarily due to unresolved issues in the blood-brain barrier (BBB)/blood-brain tumor barrier (BBTB) and GBM microenvironment. These factors limit the uptake of anti-cancer drugs by the tumor, thus limiting the therapeutic options. Current breakthroughs in nanotechnology provide new prospects concerning unconventional drug delivery approaches for GBM treatment. Specifically, swimming nanorobots show great potential in active targeted delivery, owing to their autonomous propulsion and improved navigation capacities across biological barriers, which further facilitate the development of GBM-targeted strategies. This review presents an overview of technological progress in different drug administration methods for GBM. Additionally, the limitations in clinical translation and future research prospects in this field are also discussed. This review aims to provide a comprehensive guideline for researchers and offer perspectives on further development of new drug delivery therapies to combat GBM.
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d4nr01056f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Multi-omics assists genomic prediction of maize yield with machine learning approaches.

    Wu, Chengxiu / Luo, Jingyun / Xiao, Yingjie

    Molecular breeding : new strategies in plant improvement

    2024  Volume 44, Issue 2, Page(s) 14

    Abstract: With the improvement of high-throughput technologies in recent years, large multi-dimensional plant omics data have been produced, and big-data-driven yield prediction research has received increasing attention. Machine learning offers promising ... ...

    Abstract With the improvement of high-throughput technologies in recent years, large multi-dimensional plant omics data have been produced, and big-data-driven yield prediction research has received increasing attention. Machine learning offers promising computational and analytical solutions to interpret the biological meaning of large amounts of data in crops. In this study, we utilized multi-omics datasets from 156 maize recombinant inbred lines, containing 2496 single nucleotide polymorphisms (SNPs), 46 image traits (i-traits) from 16 developmental stages obtained through an automatic phenotyping platform, and 133 primary metabolites. Based on benchmark tests with different types of prediction models, some machine learning methods, such as Partial Least Squares (PLS), Random Forest (RF), and Gaussian process with Radial basis function kernel (GaussprRadial), achieved better prediction for maize yield, albeit slight difference for method preferences among i-traits, genomic, and metabolic data. We found that better yield prediction may be caused by various capabilities in ranking and filtering data features, which is found to be linked with biological meaning such as photosynthesis-related or kernel development-related regulations. Finally, by integrating multiple omics data with the RF machine learning approach, we can further improve the prediction accuracy of grain yield from 0.32 to 0.43. Our research provides new ideas for the application of plant omics data and artificial intelligence approaches to facilitate crop genetic improvements.
    Supplementary information: The online version contains supplementary material available at 10.1007/s11032-024-01454-z.
    Language English
    Publishing date 2024-02-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1230924-2
    ISSN 1572-9788 ; 1380-3743
    ISSN (online) 1572-9788
    ISSN 1380-3743
    DOI 10.1007/s11032-024-01454-z
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    In stock of ZB MED Bonn / Germany

    Z 6088: Show issues

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  6. Article: Entrepreneurial bricolage and entrepreneurial performance: The role of business model innovation and market orientation.

    Wu, Shaoling / Luo, Yingjie / Zhang, Han / Cheng, Peng

    Heliyon

    2024  Volume 10, Issue 4, Page(s) e26600

    Abstract: Newly established enterprises in China face significant challenges and opportunities, with persistently high mortality rates. Navigating market challenges and establishing sustainable competitive advantages are pressing issues for contemporary businesses. ...

    Abstract Newly established enterprises in China face significant challenges and opportunities, with persistently high mortality rates. Navigating market challenges and establishing sustainable competitive advantages are pressing issues for contemporary businesses. This study delves into the bridging role of business model innovation between entrepreneurial bricolage and entrepreneurial performance, with market orientation influencing the relationship boundaries. We examined 288 Chinese small and medium-sized enterprises, investigating the relationships among entrepreneurial bricolage, business model innovation, market orientation, and entrepreneurial performance. Empirical results indicate: (1) Entrepreneurial bricolage positively influences business model innovation, and business model innovation positively impacts entrepreneurial performance. (2) Business model innovation plays a fully mediating positive role between entrepreneurial bricolage and entrepreneurial performance. (3) Market orientation positively moderates the impact of entrepreneurial bricolage on business model innovation and entrepreneurial performance, and it also positively moderates the impact of business model innovation on entrepreneurial performance. (4) Market orientation positively moderates the impact of entrepreneurial bricolage, mediated by business model innovation, on entrepreneurial performance. The study results contribute to a more effective understanding of the mechanisms through which entrepreneurial bricolage and business model innovation influence entrepreneurial performance, as well as how market orientation moderates their relationships and how enterprises sustain competitive advantages.
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26600
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  7. Article ; Online: CRISPR/Cas gene editing and delivery systems for cancer therapy.

    Li, Yingjie / Zhou, Shiyao / Wu, Qinjie / Gong, Changyang

    Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

    2024  Volume 16, Issue 1, Page(s) e1938

    Abstract: CRISPR/Cas systems stand out because of simplicity, efficiency, and other superiorities, thus becoming attractive and brilliant gene-editing tools in biomedical field including cancer therapy. CRISPR/Cas systems bring promises for cancer therapy through ... ...

    Abstract CRISPR/Cas systems stand out because of simplicity, efficiency, and other superiorities, thus becoming attractive and brilliant gene-editing tools in biomedical field including cancer therapy. CRISPR/Cas systems bring promises for cancer therapy through manipulating and engineering on tumor cells or immune cells. However, there have been concerns about how to overcome the numerous physiological barriers and deliver CRISPR components to target cells efficiently and accurately. In this review, we introduced the mechanisms of CRISPR/Cas systems, summarized the current delivery strategies of CRISPR/Cas systems by physical methods, viral vectors, and nonviral vectors, and presented the current application of CRISPR/Cas systems in cancer clinical treatment. Furthermore, we discussed prospects related to delivery approaches of CRISPR/Cas systems. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease.
    MeSH term(s) Humans ; Gene Editing ; CRISPR-Cas Systems ; Gene Transfer Techniques ; Genetic Vectors ; Neoplasms/genetics ; Neoplasms/therapy
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2502698-7
    ISSN 1939-0041 ; 1939-5116
    ISSN (online) 1939-0041
    ISSN 1939-5116
    DOI 10.1002/wnan.1938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6781: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: DNA nanotechnology-based nucleic acid delivery systems for bioimaging and disease treatment.

    Sun, Zhaorong / Ren, Yingjie / Zhu, Wenjun / Xiao, Yuliang / Wu, Han

    The Analyst

    2024  Volume 149, Issue 3, Page(s) 599–613

    Abstract: Nucleic acids, including DNA and RNA, have been considered as powerful and functional biomaterials owing to their programmable structure, good biocompatibility, and ease of synthesis. However, traditional nucleic acid-based probes have always suffered ... ...

    Abstract Nucleic acids, including DNA and RNA, have been considered as powerful and functional biomaterials owing to their programmable structure, good biocompatibility, and ease of synthesis. However, traditional nucleic acid-based probes have always suffered from inherent limitations, including restricted cell internalization efficiency and structural instability. In recent years, DNA nanotechnology has shown great promise for the applications of bioimaging and drug delivery. The attractive superiorities of DNA nanostructures, such as precise geometries, spatial addressability, and improved biostability, have enabled them to be a novel category of nucleic acid delivery systems for biomedical applications. In this review, we introduce the development of DNA nanotechnology, and highlight recent advances of DNA nanostructure-based delivery systems for cellular imaging and therapeutic applications. Finally, we propose the challenges as well as opportunities for the future development of DNA nanotechnology in biomedical research.
    MeSH term(s) Nucleic Acids ; Nanotechnology/methods ; DNA/genetics ; DNA/chemistry ; Nanostructures/chemistry ; Drug Delivery Systems
    Chemical Substances Nucleic Acids ; DNA (9007-49-2)
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an01871g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Confined Synthesis of Noble Metal Clusters Assisted by Liquid Film for Photocatalytic CO

    Gong, Dongkun / Wu, Yingjie / Jiang, Hao / Li, Chunzhong / Hu, Yanjie

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 14, Page(s) 7492–7501

    Abstract: The important concept of confined synthesis is considered a promising strategy for the design and synthesis of definable nanostructured materials with controllable compositions and specific morphology, such as highly loaded single-atom catalysts capable ... ...

    Abstract The important concept of confined synthesis is considered a promising strategy for the design and synthesis of definable nanostructured materials with controllable compositions and specific morphology, such as highly loaded single-atom catalysts capable of providing abundant active sites for photocatalytic reactions. In recent years, researchers have been working on developing new confined reaction systems and searching for new confined spaces. Here, we present for the first time the concept of a bubble liquid film as a novel confined space. The liquid film has a typical sandwich structure consisting of a water layer, sandwiched between the upper and lower surfactant layers, with the thickness of the intermediate water layer at the micro- and nanometer scales, which can serve as a good confinement. Based on the above understanding and combined with the photodeposition method, we successfully confined synthesized Ag/TiO
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c04020
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  10. Article ; Online: Rich-Carbonyl Carbon Catalysis Facilitating the Li

    Wu, Yingjie / Ju, Jie / Shen, Bolei / Wei, Jie / Jiang, Hao / Li, Chunzhong / Hu, Yanjie

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2311891

    Abstract: The active lithium loss of lithium-ion batteries can be well addressed by adding a cathode lithium compensation agent. Due to the poor conductivity and electrochemical activity, lithium carbonate ( ... ...

    Abstract The active lithium loss of lithium-ion batteries can be well addressed by adding a cathode lithium compensation agent. Due to the poor conductivity and electrochemical activity, lithium carbonate (Li
    Language English
    Publishing date 2024-01-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202311891
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