LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 87

Search options

  1. Article: Intra-abdominal Pressure Measurement as a Predictor of Postoperative Wound Complications in Patients Undergoing Emergency Laparotomy: A Prospective Observational Study.

    Dugar, Dharmendra / Goel, Sunny

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54860

    Abstract: Introduction Elevated intra-abdominal pressure (IAP) hampers the effective functioning of intra- and extra-abdominal organs. Despite the abundance of knowledge, routine measurement of IAP still needs to be widely incorporated in managing at-risk patients. ...

    Abstract Introduction Elevated intra-abdominal pressure (IAP) hampers the effective functioning of intra- and extra-abdominal organs. Despite the abundance of knowledge, routine measurement of IAP still needs to be widely incorporated in managing at-risk patients. The present study intends to assess the need for IAP measurement on abdominal wound healing in emergency laparotomy patients. Methods This prospective study was carried out over 24 months in patients undergoing emergency laparotomy. The IAP was measured at admission, immediately after surgery, and during the early postoperative period at 6, 12, 24, 48, and 72 hours. The patients were evaluated for the development of wound-related complications over a follow-up period of three months post-operatively. Results Seventy-two patients were enrolled. At admission, 54 (75%) patients had intra-abdominal hypertension (IAH), of which three patients had evidence of abdominal compartment syndrome. Thirty-one (43%) patients developed postoperative wound infections. The overall incidence of wound infection was significantly higher in patients with IAH (54.3% vs. 24%, p-value = 0.04, Pearson's Chi-squared test). The frequency of wound dehiscence was greater (19.6 % vs. 4.3 %, p-value 0.14, Fischer's exact test) in patients with IAH. The median duration of hospital stay (13 vs. 8 days, p-value 0.02, Mann-Whitney U test) and healing time (30.5 vs. 18 days, p-value 0.02, Mann-Whitney U test) was significantly higher in patients with IAH. Conclusion Measurement of IAP is a relatively simple procedure that should be incorporated into the routine postoperative care of surgical patients. The presence of elevated IAP can identify the subset of patients at risk of increased postoperative wound complications.
    Language English
    Publishing date 2024-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54860
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: COVID-19 pandemic and its impact on cardiology and its subspecialty training.

    Goel, Sunny / Sharma, Abhishek

    Progress in cardiovascular diseases

    2020  Volume 63, Issue 4, Page(s) 525–526

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiology/education ; Cardiology/organization & administration ; Coronavirus Infections/epidemiology ; Education, Medical, Graduate/organization & administration ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-16
    Publishing country United States
    Document type Letter
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2020.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Recurrent vesico-acetabulo-cutaneous fistula: lessons to be learnt.

    Wadhwa, Pankaj / Goel, Sunny / Talwar, Harkirat Singh / Zafar, Feroz

    BMJ case reports

    2022  Volume 15, Issue 8

    Abstract: A man in early 40s met with an accident with a complex pelvic fracture and extraperitoneal bladder injury and posterior urethral disruption 16 years ago. He additionally had left lumbar spinal segment mixed nerve injury, resulting in a foot drop. He ... ...

    Abstract A man in early 40s met with an accident with a complex pelvic fracture and extraperitoneal bladder injury and posterior urethral disruption 16 years ago. He additionally had left lumbar spinal segment mixed nerve injury, resulting in a foot drop. He underwent laparotomy and a diverting cystostomy at the time with a primary perineal urethroplasty a year later. He later developed pseudoarthrodesis of the hip joint, and poorly compliant bladder with complete block at bulbar urethra. A redo anastomotic urethroplasty was performed, hyperreflexive neurogenic bladder was managed with intravesical botox injections and underwent a hip replacement. Having defaulted botox injections, he developed a vesico-acetabulo-cutaneous fistula and the hip prosthesis was explanted. Later he underwent a ileal cystoplasty and a revision hip replacement. Ten years later, he presented with a recurrent fistula due to poor compliance with clean intermittent catheterisation. A challenging exploration with fistula excision was done with a primary bladder repair.
    MeSH term(s) Botulinum Toxins, Type A ; Cutaneous Fistula/etiology ; Cutaneous Fistula/surgery ; Humans ; Male ; Pelvic Bones/injuries ; Urethra/surgery ; Urethral Stricture/surgery ; Urinary Bladder/surgery ; Urinary Bladder Fistula/etiology ; Urinary Bladder Fistula/surgery
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2022-08-19
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-250618
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: COVID-19 pandemic and its impact on cardiology and its subspecialty training

    Goel, Sunny / Sharma, Abhishek

    Progress in Cardiovascular Diseases

    2020  Volume 63, Issue 4, Page(s) 525–526

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 209312-1
    ISSN 1532-8643 ; 1873-1740 ; 0033-0620
    ISSN (online) 1532-8643 ; 1873-1740
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2020.05.004
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article: Carcinoma bladder and sliding bladder hernia: Unusual association of paramount significance.

    Agrawal, Manav / Garg, Gaurav / Goel, Sunny / Kumar, Manoj

    Asian journal of urology

    2019  Volume 7, Issue 2, Page(s) 186–187

    Language English
    Publishing date 2019-04-30
    Publishing country Singapore
    Document type Case Reports
    ZDB-ID 2831144-9
    ISSN 2214-3882
    ISSN 2214-3882
    DOI 10.1016/j.ajur.2019.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Recent clinical trials in valvular heart diseases.

    Goel, Sunny / Ro, Richard / Lerakis, Stamatios / Khera, Sahil

    Current opinion in cardiology

    2020  Volume 35, Issue 4, Page(s) 313–318

    Abstract: Purpose of review: In recent years, no other field of cardiology has experienced a greater influx of transformational therapeutic options as valvular heart disease. The present review discusses the landmark trials published in the last 18 months that ... ...

    Abstract Purpose of review: In recent years, no other field of cardiology has experienced a greater influx of transformational therapeutic options as valvular heart disease. The present review discusses the landmark trials published in the last 18 months that have shaped the modern day management of valvular heart diseases.
    Recent findings: There have been several landmark trials in recent years, which have expanded the indications for transcatheter aortic valve replacement to low-risk surgical patients and the use of MitraClip for patients with functional mitral regurgitation. Options for transcatheter management of right-sided valvular disease also continue to evolve, including promising results from early feasibility studies.
    Summary: The development of novel transcatheter therapies for valvular heart disease has expanded the armamentarium of physicians treating patients with valvular heart disease. The present review will focus on the recent (within 2 years) trials in this field of interest.
    MeSH term(s) Cardiology ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation ; Humans ; Mitral Valve Insufficiency/surgery ; Transcatheter Aortic Valve Replacement
    Language English
    Publishing date 2020-05-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645186-x
    ISSN 1531-7080 ; 0268-4705
    ISSN (online) 1531-7080
    ISSN 0268-4705
    DOI 10.1097/HCO.0000000000000750
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Re: Churukanti et al: Role of Ultrasonography for Testicular Injuries in Penetrating Scrotal Trauma (Urology 2016;95:208-212).

    Goel, Sunny / Goel, Apul / Bansal, Ankur

    Urology

    2017  Volume 99, Page(s) 290–291

    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Letter
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2016.07.056
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Current Insights on the Photoprotective Mechanism of the Macular Carotenoids, Lutein and Zeaxanthin: Safety, Efficacy and Bio-Delivery.

    Kumar, Pawan / Banik, Samudra P / Ohia, Sunny E / Moriyama, Hiroyoshi / Chakraborty, Sanjoy / Wang, Chin-Kun / Song, Yong Sang / Goel, Apurva / Bagchi, Manashi / Bagchi, Debasis

    Journal of the American Nutrition Association

    2024  , Page(s) 1–14

    Abstract: Ocular health has emerged as one of the major issues of global health concern with a decline in quality of life in an aging population, in particular and rise in the number of associated morbidities and mortalities. One of the chief reasons for vision ... ...

    Abstract Ocular health has emerged as one of the major issues of global health concern with a decline in quality of life in an aging population, in particular and rise in the number of associated morbidities and mortalities. One of the chief reasons for vision impairment is oxidative damage inflicted to photoreceptors in rods and cone cells by blue light as well as UV radiation. The scenario has been aggravated by unprecedented rise in screen-time during the COVID and post-COVID era. Lutein and Zeaxanthin are oxygenated carotenoids with proven roles in augmentation of ocular health largely by virtue of their antioxidant properties and protective effects against photobleaching of retinal pigments, age-linked macular degeneration, cataract, and retinitis pigmentosa. These molecules are characterized by their characteristic yellow-orange colored pigmentation and are found in significant amounts in vegetables such as corn, spinach, broccoli, carrots as well as fish and eggs. Unique structural signatures including tetraterpenoid skeleton with extensive conjugation and the presence of hydroxyl groups at the end rings have made these molecules evolutionarily adapted to localize in the membrane of the photoreceptor cells and prevent their free radical induced peroxidation. Apart from the benefits imparted to ocular health, lutein and zeaxanthin are also known to improve cognitive function, cardiovascular physiology, and arrest the development of malignancy. Although abundant in many natural sources, bioavailability of these compounds is low owing to their long aliphatic backbones. Under the circumstances, there has been a concerted effort to develop vegetable oil-based carriers such as lipid nano-emulsions for therapeutic administration of carotenoids. This review presents a comprehensive update of the therapeutic potential of the carotenoids along with the challenges in achieving an optimized delivery tool for maximizing their effectiveness inside the body.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2769-707X
    ISSN (online) 2769-707X
    DOI 10.1080/27697061.2024.2319090
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Chyluria in young child: a rare presentation.

    Garg, Gaurav / Goel, Apul / Goel, Sunny / Singh, Manmeet

    BMJ case reports

    2018  Volume 2018

    Abstract: Chyluria, a chronic manifestation of lymphatic filariasis, is rare in children. Clinicians must have a high index of suspicion to diagnose this condition in children as it mimics nephrotic syndrome. We present an unusual case in which a 7-year-old boy ... ...

    Abstract Chyluria, a chronic manifestation of lymphatic filariasis, is rare in children. Clinicians must have a high index of suspicion to diagnose this condition in children as it mimics nephrotic syndrome. We present an unusual case in which a 7-year-old boy hailing from a filarial endemic region presented with a passage of milky urine, which on evaluation was diagnosed as parasitic chyluria. The child showed remission after medical management that persisted until 1 year of follow-up.
    MeSH term(s) Child ; Chyle ; Diet, Fat-Restricted ; Diethylcarbamazine/therapeutic use ; Elephantiasis, Filarial/complications ; Elephantiasis, Filarial/therapy ; Filaricides/therapeutic use ; Humans ; India ; Male ; Treatment Outcome ; Urine
    Chemical Substances Filaricides ; Diethylcarbamazine (V867Q8X3ZD)
    Language English
    Publishing date 2018-03-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2017-223516
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top