Article ; Online: Determination of the Role of Fusobacterium Nucleatum in the Pathogenesis in and Out the Mouth.
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)
2020 Volume 41, Issue 1, Page(s) 87–99
Abstract: Introduction: One of the most important types of microorganisms in the oral cavity in both healthy and non-healthy individuals is Fusobacterium nucleatum. Although present as a normal resident in the oral cavity, this Gram-negative pathogen is dominant ... ...
| Abstract | Introduction: One of the most important types of microorganisms in the oral cavity in both healthy and non-healthy individuals is Fusobacterium nucleatum. Although present as a normal resident in the oral cavity, this Gram-negative pathogen is dominant in periodontal disease and it is involved in many invasive infections in the population, acute and chronic inflammatory conditions, as well as many adverse events with a fatal outcome. Aim: To determine the role of F. nucleatum in the development of polymicrobial biofilms thus pathogenic changes in and out of the oral media. Material and method: A systematic review of the literature concerning the determination and role of F. nucleatum through available clinical trials, literature reviews, original research and articles published electronically at Pub Med and Google Scholar. Conclusion: The presence of Fusobacterium nucleatum is commonly associated with the health status of individuals. These anaerobic bacteria plays a key role in oral pathological conditions and has been detected in many systemic disorders causing complex pathogenethic changes probably due to binding ability to various cells thus several virulence mechanisms. Most common diseases and conditions in the oral cavity associated with F.nucleatum are gingivitis (G), chronic periodontitis (CH), aggressive periodontitis (AgP), endo-periodental infections (E-P), chronic apical periodontitis (PCHA). The bacterium has been identified and detected in many systemic disorders such as coronary heart disease (CVD) pathological pregnancy (P); polycystic ovary syndrome (PCOS), high-risk pregnancy (HRP), colorectal cancer (CRC); pre-eclampsia (PE); rheumatoid arthritis (RA); osteoarthritis (OA). |
|---|---|
| MeSH term(s) | Arthritis, Rheumatoid/microbiology ; Biofilms/growth & development ; Chronic Disease ; Colorectal Neoplasms/microbiology ; Coronary Disease/microbiology ; Female ; Fusobacterium nucleatum/genetics ; Fusobacterium nucleatum/growth & development ; Fusobacterium nucleatum/isolation & purification ; Fusobacterium nucleatum/pathogenicity ; Gingivitis/microbiology ; Humans ; Mouth/microbiology ; Osteoarthritis/microbiology ; Periodontal Diseases/microbiology ; Periodontitis/microbiology ; Polycystic Ovary Syndrome/microbiology ; Pre-Eclampsia/microbiology ; Pregnancy ; Pregnancy, High-Risk |
| Language | English |
| Publishing date | 2020-06-23 |
| Publishing country | North Macedonia |
| Document type | Journal Article ; Systematic Review |
| ZDB-ID | 2743787-5 |
| ISSN | 1857-8985 ; 1857-9345 |
| ISSN (online) | 1857-8985 |
| ISSN | 1857-9345 |
| DOI | 10.2478/prilozi-2020-0026 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 6857: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.