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Article ; Online: In vivo

Zhou, Yufeng / Gong, Xiaobo / You, Yaqing

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

2024 Volume 41, Issue 1, Page(s) 2325477

Abstract: Objective: Monitoring sensitivity of sonography in focused ultrasound ablation surgery (FUAS) is limited (no hyperechoes in ∼50% of successful coagulation in uterine fibroids). A more accurate and sensitive approach is required.: Method: The echo ... ...

Abstract	Objective: Monitoring sensitivity of sonography in focused ultrasound ablation surgery (FUAS) is limited (no hyperechoes in ∼50% of successful coagulation in uterine fibroids). A more accurate and sensitive approach is required. Method: The echo amplitudes of the focused ultrasound (FUS) transducer in a testing mode (short pulse duration and low power) were found to correlate with the Results: The echo amplitude changes of the FUS transducer correlate well with the lesion areas in the liver ( Conclusion: The FUS echo amplitudes are sensitive to the tissue properties and their changes after FUAS. They are sensitive and reliable in evaluating and predicting FUAS outcomes.
MeSH term(s)	Animals ; Ultrasonic Therapy ; Liver/diagnostic imaging ; Liver/surgery ; Kidney/diagnostic imaging ; Kidney/surgery ; Blood Coagulation ; Transducers
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	632526-9
ISSN	1464-5157 ; 0265-6736
ISSN (online)	1464-5157
ISSN	0265-6736
DOI	10.1080/02656736.2024.2325477
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Article ; Online: Clinical Effect of Tumor-Specific Total Nutrients in Patients with Adjuvant Chemotherapy After Radical Gastric Cancer Resection: A Randomized Controlled Trial.

Hua, Xiumei / Liu, Yang / Zhou, Yaqing

Journal of gastrointestinal cancer

2024

Abstract: Background: In this study, we combined adjuvant chemotherapy after radical gastric cancer resection with tumor-specific total nutrient therapy to analyze how it affects the nutritional state and immune function of the patient.: Method: We collected ... ...

Abstract	Background: In this study, we combined adjuvant chemotherapy after radical gastric cancer resection with tumor-specific total nutrient therapy to analyze how it affects the nutritional state and immune function of the patient. Method: We collected data from 106 patients having undergone adjuvant chemotherapy after radical gastric cancer resection between January 2020 and December 2021. We divided the patients into experimental and control groups (with 53 cases in each group) through single-blinded simple randomization using a random number table and the sealed envelope system. The control group received chemotherapy and the regular nutritional diet at the same time while the experimental group received tumor-specific total nutrients based on the control group. We analyzed the index results for the physical examination, nutritional status, and immune function of the patients in both groups recorded before and after one chemotherapeutic cycle. Results: The control and experimental group compositions were as follows: 58.5% and 52.8% males with a mean age ± standard deviation of 54.36 ± 12.68 and 55.15 ± 12.32 years, respectively. After one chemotherapeutic cycle and the nutritional intervention, the experimental group displayed better physical examination indicators than the control group concerning the weight (55.8 ± 5.41 vs. 54.8 ± 6.94, p = 0.621), body fat mass (13.3 ± 0.88 vs. 13.1 ± 0.91, p = 0.253), upper arm circumference (21.9 ± 0.94 vs. 21.2 ± 1.23 cm, p = 0.001), triceps skinfold thickness (15.1 ± 1.36 vs. 14.3 ± 1.62 cm, p = 0.007), and grip strength (23.0 ± 1.30 vs. 22.3 ± 1.33, p = 0.007). In addition, the experimental group yielded better nutritional-status indicators than the control, including albumin (35.2 ± 1.60 vs. 33.7 ± 1.44 g/L, p = 0.001), hemoglobin (115.7 ± 9.28 vs. 111.5 ± 10.56 g/L, p = 0.032), total protein (63.7 ± 5.85 vs. 60.5 ± 5.27 g/L, p = 0.004), transferrin (2.5 ± 0.53 vs. 2.2 ± 0.58 g/L, p = 0.007), and immune-function indicators CD4 Conclusion: Combined tumor-specific total nutrient and adjuvant chemotherapy application after radical gastric cancer surgery effectively improves the nutritional state and immune function of the patients and could be applied in clinical practice.
Language	English
Publishing date	2024-02-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452514-5
ISSN	1941-6636 ; 1559-0739 ; 1941-6628 ; 1537-3649
ISSN (online)	1941-6636 ; 1559-0739
ISSN	1941-6628 ; 1537-3649
DOI	10.1007/s12029-024-01029-3
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Zs.A 2184: Show issues

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Article ; Online: Drip irrigation in agricultural saline-alkali land controls soil salinity and improves crop yield: Evidence from a global meta-analysis.

Du, Yaqing / Liu, Xufei / Zhang, Lin / Zhou, Wei

The Science of the total environment

2023 Volume 880, Page(s) 163226

Abstract: Saline-alkali land, a precious candidate arable land resources, plays a critical role in achieving agricultural sustainability. Drip irrigation (DI) is an effective method for rationalizing of saline-alkali land. Nevertheless, the inapposite application ... ...

Abstract	Saline-alkali land, a precious candidate arable land resources, plays a critical role in achieving agricultural sustainability. Drip irrigation (DI) is an effective method for rationalizing of saline-alkali land. Nevertheless, the inapposite application of DI increases the risk of secondary salinization, significantly leading to severe soil degradation and yield decline. In this study, we conducted a meta-analysis to quantify the impacts of DI on soil salinity and crop yield to determine the appropriate DI management strategies for an irrigated agricultural system in saline-alkali land. The results showed that DI generally decreased soil salinity in the root zone by 37.7 % and increased crop yield by 37.4 % relative to flooding irrigation (FI). Drip emitters with a flow rate of 2-4 L h
Language	English
Publishing date	2023-04-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.163226
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Article ; Online: Effects of high-flow nasal cannula oxygen therapy for patients with acute exacerbation of chronic obstructive pulmonary disease in combination with type II respiratory failure

Aiming Liu / Yaqing Zhou / Zunguo Pu

Journal of International Medical Research, Vol

2023 Volume 51

Abstract: Objective To evaluate the therapeutic effects of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and type II respiratory failure. Methods Seventy-two patients with AECOPD ...

Abstract	Objective To evaluate the therapeutic effects of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and type II respiratory failure. Methods Seventy-two patients with AECOPD and type II respiratory failure were randomly allocated to an HFNC oxygen therapy trial group or a non-invasive positive-pressure ventilator therapy (NIPPV) control group. Their arterial blood gas parameters and comfort, evaluated using a questionnaire, were compared before and after the therapeutic interventions. Results The PaCO 2 and blood HCO 3 − concentration of both groups were significantly reduced by the treatments, whereas the pH, PaO 2 and PaO 2 /FiO 2 were increased. The PaCO 2 of the experimental group was significantly lower than that of the control group following treatment. The PaO 2 of the experimental group was significantly higher than that of the control group. The tracheal intubation rates of the two groups did not significantly differ. After treatment, all the indices of comfort were rated higher in the HFNC group than in the NIPPV group. Conclusions HFNC has a good therapeutic effect in patients with AECOPD and type II respiratory failure. It improves patient comfort and has clinical value.
Keywords	Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
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Article ; Online: Gravity-driven membrane coupled with oxidation technology to modify the surface properties and biofilm formation: Biofouling mitigation.

Du, Yaqing / Zhou, Wei / Zhang, Lin / Liu, Xufei

Journal of environmental management

2023 Volume 345, Page(s) 118444

Abstract: Biofilms caused by biological fouling play an essential role in gravity-driven membranes' (GDMs) flux decline and rejection rate. The effects of ozone, permanganate, and ferrate (VI) in-situ pretreatment on membrane properties and biofilm formation were ... ...

Abstract	Biofilms caused by biological fouling play an essential role in gravity-driven membranes' (GDMs) flux decline and rejection rate. The effects of ozone, permanganate, and ferrate (VI) in-situ pretreatment on membrane properties and biofilm formation were systematically studied. Due to the selective retention and adsorption of algal organic matter by biofilms and oxidative degradation, the rejection efficiency of dissolved organic carbon (DOC) in algae-laden water pretreated with permanganate by GDM was up to 23.63%. Pre-oxidation extraordinarily postponed flux decline and biofilm formation of GDM and reduced membrane fouling. The total membrane resistance decreased by 87.22%-90.30% within 72 h after pre-ozonation. Permanganate was more effective than ozone and ferrate (VI) in alleviating secondary membrane fouling caused by algal cells destroyed by pre-oxidation. Extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) theory revealed that the distribution of electrostatic force (EL), acid-base (AB), and Lifshitz-van der Waals forces (LW) interactions between M. aeruginosa and the released intracellular algogenic organic matter (IOM) and ceramic membrane surface was similar. The membrane and foulants are always attracted to each other by LW interaction at different separation distances. The dominant fouling mechanism of GDM combined with pre-oxidation technology shifts from complete pore blocking to cake layer filtration during operation. After pre-oxidation of algae-laden water by ozone, permanganate, and ferrate (VI), GDM can treat at least 131.8%, 37.0%, and 61.5% more feed solution before forming a complete cake layer. This study provides new insights into the biological fouling control strategies and mechanisms for GDM coupled with oxidation technology, which is expected to alleviate membrane fouling and optimize the feed liquid pretreatment procedure.
MeSH term(s)	Biofouling/prevention & control ; Filtration/methods ; Water ; Biofilms ; Surface Properties ; Ozone ; Membranes, Artificial ; Water Purification/methods ; Ultrafiltration
Chemical Substances	permanganic acid (14333-13-2) ; ferrate ion (16836-06-9) ; Water (059QF0KO0R) ; Ozone (66H7ZZK23N) ; Membranes, Artificial
Language	English
Publishing date	2023-06-27
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.118444
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Article ; Online: Effects of high-flow nasal cannula oxygen therapy for patients with acute exacerbation of chronic obstructive pulmonary disease in combination with type II respiratory failure.

Liu, Aiming / Zhou, Yaqing / Pu, Zunguo

The Journal of international medical research

2023 Volume 51, Issue 6, Page(s) 3000605231182558

Abstract: Objective: To evaluate the therapeutic effects of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and type II respiratory failure.: Methods: Seventy-two patients with ...

Abstract	Objective: To evaluate the therapeutic effects of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and type II respiratory failure. Methods: Seventy-two patients with AECOPD and type II respiratory failure were randomly allocated to an HFNC oxygen therapy trial group or a non-invasive positive-pressure ventilator therapy (NIPPV) control group. Their arterial blood gas parameters and comfort, evaluated using a questionnaire, were compared before and after the therapeutic interventions. Results: The PaCO Conclusions: HFNC has a good therapeutic effect in patients with AECOPD and type II respiratory failure. It improves patient comfort and has clinical value.
MeSH term(s)	Humans ; Cannula ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/therapy ; Oxygen Inhalation Therapy ; Respiratory Insufficiency/etiology ; Oxygen ; Noninvasive Ventilation
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-06-28
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/03000605231182558
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Article ; Online: Design, synthesis and activity evaluation of pseudilin analogs against cyanobacteria as IspD inhibitors.

Wang, Jili / Wu, Wenhai / Zhou, Yaqing / Han, Mengying / Zhou, Xin / Sun, Yong / Zhang, Aidong

Pesticide biochemistry and physiology

2024 Volume 199, Page(s) 105769

Abstract: The discovery of safe, effective, and selective chemical algicides is the stringent need for the algicides development, and it is also one of the effective routes to control cyanobacteria harmful algal blooms and to meet the higher requirements of ... ...

Abstract	The discovery of safe, effective, and selective chemical algicides is the stringent need for the algicides development, and it is also one of the effective routes to control cyanobacteria harmful algal blooms and to meet the higher requirements of environmental and ecological. In this work, a series of novel bromo-N-phenyl-5-o-hydroxyphenylpyrazole-3-carboxyamides were rationally designed as pseudilin analogs by bioisosteric replacement and molecular hybridization strategies, in which the pyrrole unit of pseudilin was replaced with pyrazole and further combined with the dominant structural fragments of algicide diuron. The synthesis was carried out by a facile four-step routeincluding cyclization, amidation, transanulation, and halogenation. The biological activity evaluation on AtIspD, EcIspD, Synechocystis sp. PCC6803 and Microcystis aeruginosa FACHB905 revealed that most compounds had good EcIspD and excellent cyanobacteria inhibitory activity. In particular, compound 6bb exhibited potent algicidal activity against PCC6803 and FACHB905 with EC
MeSH term(s)	Molecular Docking Simulation ; Enzyme Inhibitors/pharmacology ; Synechocystis/chemistry ; Synechocystis/metabolism ; Microcystis ; Herbicides/pharmacology
Chemical Substances	Enzyme Inhibitors ; Herbicides
Language	English
Publishing date	2024-01-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	184819-7
ISSN	1095-9939 ; 0048-3583 ; 0048-3575
ISSN (online)	1095-9939
ISSN	0048-3583 ; 0048-3575
DOI	10.1016/j.pestbp.2024.105769
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Article: Clinical effect of high-flow nasal cannula oxygen therapy combined with naloxone on severe respiratory failure in older adult patients: a randomized controlled trial.

Zhou, Yaqing / Shi, Xiaoyan / Pu, Zunguo / Liu, Aiming

American journal of translational research

2023 Volume 15, Issue 11, Page(s) 6613–6620

Abstract: Objective: To analyze the clinical effect of high-flow nasal cannula (HFNC) oxygen therapy combined with naloxone on severe respiratory failure (SRF) in older adult patients.: Methods: We enrolled 96 older adult patients with SRF who were admitted to ...

Abstract	Objective: To analyze the clinical effect of high-flow nasal cannula (HFNC) oxygen therapy combined with naloxone on severe respiratory failure (SRF) in older adult patients. Methods: We enrolled 96 older adult patients with SRF who were admitted to Hai'an People's Hospital between February 2019 and March 2022. The patients were divided into two groups: the control group (treated with non-invasive positive pressure ventilation combined with naloxone) and the observation group (treated with HFNC oxygen therapy combined with naloxone). The blood gas measurement, respiratory rate (RR), St. George's Respiratory Questionnaire (SGRQ) score, Clara cell secreted protein (CC16) level, tumor necrosis factor-alpha (TNF-α) level, interleukin-1 (IL-1) level, length of intensive care unit (ICU) stay, tracheal intubation rate, and 28-day mortality rate were compared between the groups. Results: Blood gas measurement or RR did not differ significantly between the groups ( Conclusions: HFNC oxygen therapy combined with naloxone in older adult patients with SRF could improve blood gas results, disease duration, tracheal intubation rate, and 28-day mortality rate. This may occur through regulation of TNF-α, IL-1, and CC16 expression.
Language	English
Publishing date	2023-11-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
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Article ; Online: Establishment of animal models and behavioral studies for autism spectrum disorders.

Jiao, Daiyan / Xu, Yingkai / Tian, Fei / Zhou, Yaqing / Chen, Dong / Wang, Yujue

The Journal of international medical research

2024 Volume 52, Issue 4, Page(s) 3000605241245293

Abstract: In recent years, the incidence of autism spectrum disorder (ASD) has increased, but the etiology and pathogenesis remain unclear. In this narrative review, we review and systematically summarize the methods used to construct animal models to study ASD ... ...

Abstract	In recent years, the incidence of autism spectrum disorder (ASD) has increased, but the etiology and pathogenesis remain unclear. In this narrative review, we review and systematically summarize the methods used to construct animal models to study ASD and the related behavioral studies based on recent literature. Utilization of various ASD animal models can complement research on the etiology, pathogenesis, and core behaviors of ASD, providing information and a foundation for further basic research and clinical treatment of ASD.
MeSH term(s)	Animals ; Autism Spectrum Disorder/genetics ; Models, Animal
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/03000605241245293
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Article ; Online: Fabrication of Au nanoclusters confined on hydroxy double salt-based intelligent biosensor for on-site monitoring of urease and its inhibitors.

Han, Yaqing / Wang, Mengke / Xie, Han / Zhou, Yitong / Wang, Shun / Wang, Guannan

Talanta

2024 Volume 271, Page(s) 125725

Abstract: Sensitive and convenient sensing of urease and its inhibitors is exceptionally urgent in clinical diagnosis and new drug development. In this study, the gold nanoclusters (AuNCs) and hydroxyl double salt (HDS) were composited by a simple confinement ... ...

Abstract	Sensitive and convenient sensing of urease and its inhibitors is exceptionally urgent in clinical diagnosis and new drug development. In this study, the gold nanoclusters (AuNCs) and hydroxyl double salt (HDS) were composited by a simple confinement effect to prepare highly fluorescent AuNCs@HDS composites to monitor urease and its drug inhibitors. HDS was used as a matrix to confine AuNCs (AuNCs@HDS), facilitating the emission intensity of AuNCs. However, acidic conditions (low pH) can disrupt the structure of HDS to break the confinement effect, and quench the fluorescence of AuNCs. Therefore, a sensing platform for pH-related enzyme urease detection was constructed based on the sensitive response of AuNCs@HDS to pH. This sensing platform had a linear response range of 0.5-22.5 U/L and a low limit of detection (LOD) of 0.19 U/L for urease. Moreover, this sensing platform was also applied to monitor urease inhibitors and urease in human saliva samples. Additionally, a portable hydrogel kit combined with a smartphone was developed for urease detection to achieve portable, low-cost, instrument-free, and on-site monitoring of urease.
MeSH term(s)	Humans ; Urease ; Sodium Chloride ; Biosensing Techniques ; Gold/chemistry ; Metal Nanoparticles/chemistry ; Spectrometry, Fluorescence
Chemical Substances	Urease (EC 3.5.1.5) ; Sodium Chloride (451W47IQ8X) ; Gold (7440-57-5)
Language	English
Publishing date	2024-01-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1500969-5
ISSN	1873-3573 ; 0039-9140
ISSN (online)	1873-3573
ISSN	0039-9140
DOI	10.1016/j.talanta.2024.125725
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