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Article ; Online: The effects of land use types on microplastics in river water: A case study on the mainstream of the Wei River, China.

Zhang, Le / Li, Xi / Li, Qi / Xia, Xiaoqiang / Zhang, Hang

2024 Volume 196, Issue 4, Page(s) 349

Abstract: ... ecological environment. The Wei River is a first-class tributary of the Yellow River, the fifth largest river ... in this river is not clear. Based on this, the spatiotemporal distribution of microplastics in the Wei River ...

Abstract	Microplastics are widely found in rivers and their sediments, which will cause harm to the water ecological environment. The Wei River is a first-class tributary of the Yellow River, the fifth largest river in the world, and has vulnerable ecological environment and most sediment in the world. However, understanding how anthropogenic activities and environmental factors affect the microplastics distribution in this river is not clear. Based on this, the spatiotemporal distribution of microplastics in the Wei River were investigated. The abundance of microplastics ranged from 1033 to 8333 items/m
MeSH term(s)	Microplastics ; Plastics ; Rivers ; Water Pollutants, Chemical/analysis ; Environmental Monitoring ; Water ; China
Chemical Substances	Microplastics ; Plastics ; Water Pollutants, Chemical ; Water (059QF0KO0R)
Language	English
Publishing date	2024-03-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-024-12430-7
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Article ; Online: Assessing ecological health in a semi-arid basin: a case study of the Wei River Basin, China.

Yang, Yonglin / Cao, Hongye / Xia, Yuyun / Liu, Dong / Liu, Yang / Qiao, Jianwei

Environmental science and pollution research international

2024 Volume 31, Issue 14, Page(s) 21687–21708

Abstract: ... health has emerged as a primary focus in current research. In this study, we selected the Wei River Basin ... River Ecological Health Assessment Index (REHAI) system. The research findings indicate that the Wei ... as sub-healthy. Furthermore, we observed variations within the Wei River system itself; the upper reaches ...

Abstract	A healthy water ecosystem within a river basin is essential for maintaining ecological security, preserving species diversity, and ensuring sustainable socio-economic development. Unfortunately, human activities have significantly threatened the health of water ecosystems in various basins. Consequently, timely restoration and targeted protection of damaged river ecosystems have become crucial objectives in watershed management. As a prerequisite and cornerstone for river protection and management, assessing river ecological health has emerged as a primary focus in current research. In this study, we selected the Wei River Basin, a representative area of the Yellow River Basin, as our research subject. We identified multiple influencing factors, including society, biology, water quality, and habitat, which collectively impact this semi-arid region. To assess the overall impact of these factors on ecological health, we developed a comprehensive River Ecological Health Assessment Index (REHAI) system. The research findings indicate that the Wei River system, as a whole, is currently in a healthy state, while the Jing and Luo River systems are classified as sub-healthy. Furthermore, we observed variations within the Wei River system itself; the upper reaches of the Wei River exhibit higher levels of health compared to the middle reaches, whereas the water environment in the lower reaches is the most compromised. This degradation can be attributed to downstream subsidence, increased pollution, and rapid urbanization. By establishing a river ecosystem health assessment methodology and conducting a comprehensive evaluation of the health status of river ecosystems, this paper puts forward management recommendations for river basins. These findings provide a scientific basis for the sustainable utilization of water resources in river basins and promote the harmonious coexistence of humanity and nature.
MeSH term(s)	Humans ; Ecosystem ; Water Quality ; Water Resources ; Rivers ; China
Language	English
Publishing date	2024-02-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-32377-z
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Article ; Online: Qi Wei anti-burn Tincture remodels liver metabolic pathways and treats burn wounds efficiently.

Wang, Shuai / Zhou, Hui / Cui, Weiqi / Zhang, Junwei / Wu, Deqiao / Zhang, Nan / Xu, Xia

Journal of burn care & research : official publication of the American Burn Association

2022

Abstract: This work aims to elucidate the molecular mechanism of Qi Wei anti-burn Tincture (QW ... Qi Wei anti-burn Tincture treatment did promote the healing of the burn wounds on Kunming mice ... that Qi Wei anti-burn Tincture reprogramed the above metabolic processes in the liver. Furthermore ...

Abstract	This work aims to elucidate the molecular mechanism of Qi Wei anti-burn Tincture (QW) on wound healing in burnt mice using metabolomics and molecular biology techniques. A scald model was first established in Kunming mice. After treatment, biochemical indicators for liver function and burnt skin tissues were then evaluated via biochemical detection and HE staining respectively. Liver tissues were further analyzed for differential metabolites, inflammatory factors, and mRNA levels of cytokines using metabolomics and molecular biology techniques. Involved metabolic pathways were also identified using software. Qi Wei anti-burn Tincture treatment did promote the healing of the burn wounds on Kunming mice with a downregulation of ALP, ALT, AST to normal levels. In mouse liver tissue, the contents of glutamine, aspartic acid, succinic acid and citrulline were significantly reduced, while the contents of 5-hydroxyproline, taurine, hypotaurine and glutamic acid significantly increased. These major differential compounds are involved in the arginine metabolic pathway, nitrogen excretion, and the metabolism of taurine and hypotaurine, suggesting that Qi Wei anti-burn Tincture reprogramed the above metabolic processes in the liver. Furthermore, the application of Qi Wei anti-burn Tincture increased the expression of TGF-β1 and FGF-2, and reduced the levels of TNF-α, IL-1β, IL-6 and reactive oxygen species in the liver of mice induced by burn injury. This study found that Qi Wei anti-burn Tincture treatment promoted metabolic pathway remodeling in liver, which might be a potential mechanism for Qi Wei anti-burn Tincture to treat burn wounds.
Language	English
Publishing date	2022-11-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2224246-6
ISSN	1559-0488 ; 1559-047X
ISSN (online)	1559-0488
ISSN	1559-047X
DOI	10.1093/jbcr/irac175
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Article ; Online: Response of aerosol composition to the clean air actions in Baoji city of Fen-Wei River Basin.

Wang, Yichen / Li, Xia / Wang, Qiyuan / Zhou, Bianhong / Liu, Suixin / Tian, Jie / Hao, Qiang / Li, Guohui / Han, Yongming / Hang Ho, Steven Sai / Cao, Junji

Environmental research

2022 Volume 210, Page(s) 112936

Abstract: ... control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is ... Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron ...

Abstract	The implementation of air pollution control measures could alter the compositions of submicron aerosols. Identifying the changes can evaluate the atmospheric responses of the implemented control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is the most air polluted region in China, and thereby is a key area for the reduction of emissions. Only limited studies determine the changes in the chemical compositions of submicron aerosols. In this study, Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron aerosols were determined between 2014 and 2019. Organic fractions were determined through an online instrument (Quadrupole Aerosol Chemical Speciation Monitor, Q-ACSM) and source recognition was performed by the Multilinear Engine (ME-2). The Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) was also employed to evaluate the contributions of emissions reduction and meteorological conditions to the changes of submicron aerosol compositions. The results indicate that the mass concentrations of submicron aerosols have been substantially decreased after implementation of air pollution control measures. This was mainly attributed to the emission reductions of sulfur dioxide (SO
MeSH term(s)	Aerosols/analysis ; Air Pollutants/analysis ; Air Pollution/analysis ; Air Pollution/prevention & control ; China ; Environmental Monitoring/methods ; Nitrates ; Nitrogen Oxides/analysis ; Particulate Matter/analysis ; Rivers
Chemical Substances	Aerosols ; Air Pollutants ; Nitrates ; Nitrogen Oxides ; Particulate Matter
Language	English
Publishing date	2022-02-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.112936
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Article ; Online: UPLC-Q-TOF-MS/MS Combined with Network Pharmacology, Molecular Docking, and Animal Verification Reveals the Mechanism of Insomnia Treatment by Shen Qi Wu Wei Zi capsules.

Bai, Fengyun / Wang, Jie / Xia, Ning / Sun, Ying / Xie, Yundong / Zhao, Chongbo / Sun, Jing / Zhang, Xiaofei

Combinatorial chemistry & high throughput screening

2023

Abstract: Background: Shen Qi Wu Wei Zi capsules (SQWWZ) are often used to treat insomnia ... the mechanism underlying the therapeutic effects of the Shen Qi Wu Wei Zi capsules on insomnia.: Methods ...

Abstract	Background: Shen Qi Wu Wei Zi capsules (SQWWZ) are often used to treat insomnia; however, the potential therapeutic mechanism is still unclear. Objective: This study aimed to investigate the mechanism underlying the therapeutic effects of the Shen Qi Wu Wei Zi capsules on insomnia. Methods: The components of SQWWZ were identified using the UPLC-Q-TOF-MS/MS technique in conjunction with relevant literature. Insomnia-related targets were searched in the GeneCards and DisGeNET databases, and the intersection targets were obtained using a Venn diagram. A component-target-insomnia network diagram was constructed using Cytoscape 3.7.2 software. Core targets underwent GO and KEGG enrichment analyses. Molecular docking techniques were employed to verify the key proteins involved in the pathway and their corresponding compounds. Insomnia was induced in SD rats through the intraperitoneal injection of pchlorophenylalanine (DL-4-chlorophenylalanine, PCPA). The rats were treated orally with SQWWZ, and the serum levels of 5-HT and GABA in each group were determined using ELISA. Histological analysis of hippocampal tissue sections from the rats was performed using HE staining. Results: Using UPLC-Q-TOF-MS/MS and reviewing relevant literature, we identified 49 components of SQWWZ. Additionally, we obtained 1,043 drug targets and 367 insomnia-related targets. Among these, 82 targets were found to be common to both drug and insomnia targets. Following drug administration, rats in the treatment group exhibited a significant increase in the serum levels of 5-HT and GABA. Moreover, histological analysis using HE staining revealed neatly arranged hippocampal neuronal cells in the treated rats. Conclusion: The active components of SQWWZ had good inhibition of insomnia. This study provides a reference and guidance for the in-depth study of SQWWZ for the treatment of insomnia.
Language	English
Publishing date	2023-12-27
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2064785-2
ISSN	1875-5402 ; 1386-2073
ISSN (online)	1875-5402
ISSN	1386-2073
DOI	10.2174/0113862073275553231202153259
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Article ; Online: Characteristics of the traditional Liu-Wei-Di-Huang prescription reassessed in modern pharmacology.

Cheng, Xiao-Rui / Qi, Chun-Hui / Wang, Tong-Xing / Zhou, Wen-Xia / Zhang, Yong-Xiang

Chinese journal of natural medicines

2019 Volume 17, Issue 2, Page(s) 103–121

Abstract: Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription ...

Abstract	Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription in traditional Chinese medicine with promising pharmacological characteristics that can be further exploited and developed in modern medicine. We provide a comprehensive and detailed literature report on the clinical and experimental pharmacology of LW, including its quality control parameters, phytochemistry, pharmacokinetics, and toxicology. Our literature review indicates that the LW prescription possesses a unique combination of pharmacological characteristics that can be safely used for treating very different diseases. Quality control and pharmacokinetic parameters of LW are mostly based on its major bioactive phytochemical constituents. We postulate that modulating or rebalancing the neuroendocrine immunomodulation network in the body is the underlying mechanism of the multiple pharmacological activities displayed by LW.
MeSH term(s)	Animals ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Kidney/drug effects ; Medicine, Chinese Traditional ; Neuroimmunomodulation/drug effects ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Quality Control ; Yin Deficiency/drug therapy
Chemical Substances	Drugs, Chinese Herbal ; Liuwei Dihuang Decoction ; Phytochemicals
Language	English
Publishing date	2019-02-22
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(19)30013-5
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Article: Response of aerosol composition to the clean air actions in Baoji city of Fen-Wei River Basin

Wang, Yichen / Li, Xia / Wang, Qiyuan / Zhou, Bianhong / Liu, Suixin / Tian, Jie / Hao, Qiang / Li, Guohui / Han, Yongming / Hang Ho, Steven Sai / Cao, Junji

Environmental research. 2022 July, v. 210

2022

Abstract	The implementation of air pollution control measures could alter the compositions of submicron aerosols. Identifying the changes can evaluate the atmospheric responses of the implemented control measures and provide more scientific basis for the formulation of new measures. The Fen-Wei River Basin is the most air polluted region in China, and thereby is a key area for the reduction of emissions. Only limited studies determine the changes in the chemical compositions of submicron aerosols. In this study, Baoji was selected as a representative city in the Fen-Wei River Basin. The compositions of submicron aerosols were determined between 2014 and 2019. Organic fractions were determined through an online instrument (Quadrupole Aerosol Chemical Speciation Monitor, Q-ACSM) and source recognition was performed by the Multilinear Engine (ME-2). The Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) was also employed to evaluate the contributions of emissions reduction and meteorological conditions to the changes of submicron aerosol compositions. The results indicate that the mass concentrations of submicron aerosols have been substantially decreased after implementation of air pollution control measures. This was mainly attributed to the emission reductions of sulfur dioxide (SO₂) and primary organic aerosol (POA). In addition, the main components that drove the pollution episodes swapped from POA, sulfate, nitrate and less-oxidized organic (LO-OOA) in 2014 to nitrate and more-oxidized OOA (MO-OOA) in 2019. Due to the changes of chemical compositions of both precursors and secondary pollutants, the pollution control measures should be modernized to focus on the emissions of ammonia (NH₃), nitrogen oxides (NOₓ) and volatile organic compounds (VOCₛ) in this region.
Keywords	aerosols ; air ; air pollution control ; ammonia ; chemical speciation ; nitrates ; nitrogen ; pollution ; research ; sulfates ; sulfur dioxide ; volatile organic compounds ; watersheds
Language	English
Dates of publication	2022-07
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2022.112936
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Article: Multi-Objective Optimal Operations Based on Improved NSGA-II for Hanjiang to Wei River Water Diversion Project, China

Wu, Lianzhou / Bai, Tao / Huang, Qiang / Liu, Xia / Wei, Jian

Water. 2019 June 02, v. 11, no. 6

2019

Abstract: ... in intake areas. Given the multifaceted demands of the Hanjiang to Wei River Water Diversion Project, China ...

Abstract	It is important to investigate the laws of reservoir multi-objective optimization operations, because it can obtain the best benefits from inter-basin water transfer projects to mitigate water shortage in intake areas. Given the multifaceted demands of the Hanjiang to Wei River Water Diversion Project, China (referred hereafter as “the Project”), an easy-to-operate multi-objective optimal model based on simulation is built and applied to search the multi-objective optimization operation rules between power generation and energy consumption. The Project includes two reservoirs connected by a water transfer tunnel. One is Huangjinxia, located in the mainstream of Hanjiang with abundant inflow but no regulation ability, and the other is Sanhekou, located in the tributary of Hanjiang with multi-year regulation ability but less water. The layout of the Project increases the difficulty of reservoir joint optimization operations. Therefore, an improved Non-dominated Sorting Genetic Algorithm-II (I-NSGA-II) with a feasible search space is proposed to solve the model based on long-term series data. The results show that: (1) The validated simulation model is helpful to obtain Pareto front curves to reveal the rules between power generation and energy consumption. (2) Choosing a reasonable search step size to build a feasible search space based on simulation results for the I-NSGA-II can help find more optimized solutions. Considering the influence of the initial populations of the algorithm and limited computing ability of computers, the qualified rate of Pareto points solved by I-NSGA-II are superior to NSGA-II. (3) According to the characteristics of the Project, water transfer ratio threshold value of two reservoirs are quantified for maximize economic benefits. Moreover, the flood season is a critical operation period for the Project, in which both reservoirs should supply more water to intake areas to ensure the energy balanced of the entire system. The findings provide an easy-to-operate multi-objective operation model with the I-NSGA-II that can easily be applied in optimal management of inter-basin water transfer projects by relevant authorities.
Keywords	algorithms ; computers ; energy ; financial economics ; power generation ; river water ; simulation models ; water shortages ; China
Language	English
Dates of publication	2019-0602
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2521238-2
ISSN	2073-4441
ISSN	2073-4441
DOI	10.3390/w11061159
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Article ; Online: Identification of sources, characteristics and photochemical transformations of dissolved organic matter with EEM-PARAFAC in the Wei River of China

Luo, Yuanyuan / Zhang, Yangyang / Lang, Mengfan / Guo, Xuetao / Xia, Tianjiao / Wang, Tiecheng / Jia, Hanzhong / Zhu, Lingyan

Front. Environ. Sci. Eng.. 2021 Oct., v. 15, no. 5 p.96-96

2021

Abstract: ... the sources and characteristics of DOM in surface water and sediment samples of the Wei River, China ... rapidly. These data describe the characteristics of DOM in the Wei River and are crucial to understanding ...

Abstract	Dissolved organic matter (DOM) in rivers is a critical regulator of the cycling and toxicity of pollutants and the behavior of DOM is a key indicator for the health of the environment. We investigated the sources and characteristics of DOM in surface water and sediment samples of the Wei River, China. Dissolved organic carbon (DOC) concentration and ultraviolet absorbance at 254 nm (UV₂₅₄) increased in the surface water and were decreased in the sediment downstream, indicating that the source of DOM in the water differed from the sediment. Parallel factor (PARAFAC) analysis of the excitation-emission matrices (EEM) revealed the presence of terrestrial humus-like, microbial humus-like and tryptophan-like proteins in the surface water, whereas the sediment contained UVA humic-like, UVC humic-like and fulvic-like in the sediment. The DOM in the surface water and sediment were mainly derived from microbial metabolic activity and the surrounding soil. Surface water DOM displayed greater photodegradation potential than sediment DOM. PARAFAC analysis indicated that the terrestrial humic-like substance in the water and the fulvic-like component in the sediment decomposed more rapidly. These data describe the characteristics of DOM in the Wei River and are crucial to understanding the fluctuations in environmental patterns.
Keywords	absorbance ; biochemical pathways ; dissolved organic carbon ; photolysis ; rivers ; sediments ; soil ; surface water ; toxicity ; China
Language	English
Dates of publication	2021-10
Size	p. 96.
Publishing place	Higher Education Press
Document type	Article ; Online
Note	NAL-AP-2-clean
ZDB-ID	2662203-8
ISSN	2095-221X ; 2095-2201
ISSN (online)	2095-221X
ISSN	2095-2201
DOI	10.1007/s11783-020-1340-z
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Article: Characteristics of the traditional Liu-Wei-Di-Huang prescription reassessed in modern pharmacology

CHENG, Xiao-Rui / QI, Chun-Hui / WANG, Tong-Xing / ZHANG, Yong-Xiang / ZHOU, Wen-Xia

Chinese journal of natural medicines. 2019 Feb., v. 17, no. 2

2019

Abstract: Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription ...

Abstract	Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription in traditional Chinese medicine with promising pharmacological characteristics that can be further exploited and developed in modern medicine. We provide a comprehensive and detailed literature report on the clinical and experimental pharmacology of LW, including its quality control parameters, phytochemistry, pharmacokinetics, and toxicology. Our literature review indicates that the LW prescription possesses a unique combination of pharmacological characteristics that can be safely used for treating very different diseases. Quality control and pharmacokinetic parameters of LW are mostly based on its major bioactive phytochemical constituents. We postulate that modulating or rebalancing the neuroendocrine immunomodulation network in the body is the underlying mechanism of the multiple pharmacological activities displayed by LW.
Keywords	chemical constituents of plants ; immunomodulation ; kidneys ; medicinal properties ; Oriental traditional medicine ; pharmacokinetics ; quality control ; toxicology
Language	English
Dates of publication	2019-02
Size	p. 103-121.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(19)30013-5
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