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  1. Article ; Online: Imaging of COVID-19.

    Toussie, Danielle / Voutsinas, Nicholas / Chung, Michael / Bernheim, Adam

    Seminars in roentgenology

    2021  Volume 57, Issue 1, Page(s) 40–52

    Abstract: The novel coronavirus disease 2019 (COVID-19) emerged as the source of a global pandemic in late 2019 and early 2020 and quickly spread throughout the world becoming one of the worst pandemics in recent history. This chapter reviews the most up to date ... ...

    Abstract The novel coronavirus disease 2019 (COVID-19) emerged as the source of a global pandemic in late 2019 and early 2020 and quickly spread throughout the world becoming one of the worst pandemics in recent history. This chapter reviews the most up to date radiological literature and outlines the utility of thoracic imaging in COVID-19, defining both the common and the less typical imaging appearances during the acute and subacute phases of COVID-19. The short term complications and the long term sequela will also be discussed in the context of radiology, including pulmonary emboli, acute respiratory distress syndrome, superimposed infections, barotrauma, cardiac manifestations, pulmonary parenchymal scarring and fibrosis.
    MeSH term(s) COVID-19 ; Humans ; Lung/diagnostic imaging ; Radiography ; SARS-CoV-2
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80310-8
    ISSN 1558-4658 ; 0037-198X
    ISSN (online) 1558-4658
    ISSN 0037-198X
    DOI 10.1053/j.ro.2021.10.002
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  2. Article ; Online: Current imaging of PE and emerging techniques: is there a role for artificial intelligence?

    Azour, Lea / Ko, Jane P / Toussie, Danielle / Gomez, Geraldine Villasana / Moore, William H

    Clinical imaging

    2022  Volume 88, Page(s) 24–32

    Abstract: Acute pulmonary embolism (PE) is a critical, potentially life-threatening finding on contrast-enhanced cross-sectional chest imaging. Timely and accurate diagnosis of thrombus acuity and extent directly influences patient management, and outcomes. ... ...

    Abstract Acute pulmonary embolism (PE) is a critical, potentially life-threatening finding on contrast-enhanced cross-sectional chest imaging. Timely and accurate diagnosis of thrombus acuity and extent directly influences patient management, and outcomes. Technical and interpretive pitfalls may present challenges to the radiologist, and by extension, pose nuance in the development and integration of artificial intelligence support tools. This review delineates imaging considerations for diagnosis of acute PE, and rationale, hurdles and applications of artificial intelligence for the PE task.
    MeSH term(s) Acute Disease ; Artificial Intelligence ; Cross-Sectional Studies ; Diagnostic Imaging ; Humans ; Pulmonary Embolism/diagnostic imaging
    Language English
    Publishing date 2022-05-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2022.05.003
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  3. Article ; Online: Incidental CT findings in the lungs in COVID-19 patients presenting with abdominal pain.

    Voutsinas, Nicholas / Toussie, Danielle / Jacobi, Adam / Bernheim, Adam / Chung, Michael

    Clinical imaging

    2020  Volume 67, Page(s) 1–4

    Abstract: As the 2019 novel coronavirus disease (COVID-19) continues to spread, some patients are presenting with abdominal symptoms without respiratory complaints. Our case series documents four patients who presented with abdominal symptoms whose abdominopelvic ... ...

    Abstract As the 2019 novel coronavirus disease (COVID-19) continues to spread, some patients are presenting with abdominal symptoms without respiratory complaints. Our case series documents four patients who presented with abdominal symptoms whose abdominopelvic CT revealed incidental pulmonary parenchymal findings in the imaged lung bases and were subsequently confirmed positive for COVID-19 via laboratory testing. It remains to be seen whether these patients will eventually develop respiratory symptoms. While it is possible that the patients' abdominal complaints are coincidental with CT findings, it is interesting that patients can have such extensive incidental disease in the lungs on CT without respiratory symptoms.
    MeSH term(s) Abdominal Pain/complications ; Adult ; Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Female ; Humans ; Lung/pathology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-05-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2020.05.021
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  4. Article ; Online: Influence of coronary dominance on coronary artery calcification burden.

    Azour, Lea / Steinberger, Sharon / Toussie, Danielle / Titano, Ruwanthi / Kukar, Nina / Babb, James / Jacobi, Adam

    Clinical imaging

    2021  Volume 77, Page(s) 283–286

    Abstract: Objective: To evaluate the influence of coronary artery dominance on observed coronary artery calcification burden in outpatients presenting for coronary computed tomography angiography (CCTA).: Methods: A 12-month retrospective review was performed ... ...

    Abstract Objective: To evaluate the influence of coronary artery dominance on observed coronary artery calcification burden in outpatients presenting for coronary computed tomography angiography (CCTA).
    Methods: A 12-month retrospective review was performed of all CCTAs at a single institution. Coronary arterial dominance, Agatston score and presence or absence of cardiovascular risk factors including hypertension (HTN), hyperlipidemia (HLD), diabetes and smoking were recorded. Dominance groups were compared in terms of calcium score adjusted for covariates using analysis of covariance based on ranks. Only covariates observed to be significant independent predictors of the relevant outcome were included in each analysis. All statistical tests were conducted at the two-sided 5% significance level.
    Results: 1223 individuals, 618 women and 605 men were included, mean age 60 years (24-93 years). Right coronary dominance was observed in 91.7% (n = 1109), left dominance in 8% (n = 98), and codominance in 1.3% (n = 16). The distribution of patients among Agatston score severity categories significantly differed between codominant and left (p = 0.008), and codominant and right (p = 0.022) groups, with higher prevalence of either zero or severe CAC in the codominant patients. There was no significant difference in Agatston score between dominance groups. In the subset of individuals with coronary artery calcification, Agatston score was significantly higher in codominant versus left dominant patients (mean Agatston score 595 ± 520 vs. mean 289 ± 607, respectively; p = 0.049), with a trend towards higher scores in comparison to the right-dominant group (p = 0.093). Significance was not maintained upon adjustment for covariates.
    Conclusions: While the distribution of Agatston score severity categories differed in codominant versus right- or left-dominant patients, there was no significant difference in Agatston score based on coronary dominance pattern in our cohort. Reporting and inclusion of codominant subsets in larger investigations may elucidate whether codominant anatomy is associated with differing risk.
    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/epidemiology ; Coronary Vessels/diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/epidemiology
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2021.06.008
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  5. Article ; Online: Differentiating Imaging Features of Post-lobectomy Right Middle Lobe Torsion.

    Tamizuddin, Farah / Ocal, Selin / Toussie, Danielle / Azour, Lea / Wickstrom, Maj / Moore, William H / Kent, Amie / Babb, James / Fansiwala, Kush / Flagg, Eric / Ko, Jane P

    Journal of thoracic imaging

    2023  

    Abstract: Purpose: The purpose of this study was to identify differences in imaging features between patients with confirmed right middle lobe (RML) torsion compared to those suspected yet without torsion.: Materials and methods: This retrospective study ... ...

    Abstract Purpose: The purpose of this study was to identify differences in imaging features between patients with confirmed right middle lobe (RML) torsion compared to those suspected yet without torsion.
    Materials and methods: This retrospective study entailing a search of radiology reports from April 1, 2014, to April 15, 2021, resulted in 52 patients with suspected yet without lobar torsion and 4 with confirmed torsion, supplemented by 2 additional cases before the search period for a total of 6 confirmed cases. Four thoracic radiologists (1 an adjudicator) evaluated chest radiographs and computed tomography (CT) examinations, and Fisher exact and Mann-Whitney tests were used to identify any significant differences in imaging features (P<0.05).
    Results: A reversed halo sign was more frequent for all readers (P=0.001) in confirmed RML torsion than patients without torsion (83.3% vs. 0% for 3 readers, one the adjudicator). The CT coronal bronchial angle between RML bronchus and bronchus intermedius was larger (P=0.035) in torsion (121.28 degrees) than nontorsion cases (98.26 degrees). Patients with torsion had a higher percentage of ground-glass opacity in the affected lobe (P=0.031). A convex fissure towards the adjacent lobe on CT (P=0.009) and increased lobe volume on CT (P=0.001) occurred more often in confirmed torsion.
    Conclusion: A reversed halo sign, larger CT coronal bronchial angle, greater proportion of ground-glass opacity, fissural convexity, and larger lobe volume on CT may aid in early recognition of the rare yet highly significant diagnosis of lobar torsion.
    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/RTI.0000000000000736
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  6. Article ; Online: Incidental CT findings in the lungs in COVID-19 patients presenting with abdominal pain

    Voutsinas, Nicholas / Toussie, Danielle / Jacobi, Adam / Bernheim, Adam / Chung, Michael

    Clinical Imaging

    2020  Volume 67, Page(s) 1–4

    Keywords Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1028123-x
    ISSN 0899-7071
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2020.05.021
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  7. Article: Incidental CT findings in the lungs in COVID-19 patients presenting with abdominal pain

    Voutsinas, Nicholas / Toussie, Danielle / Jacobi, Adam / Bernheim, Adam / Chung, Michael

    Clin Imaging

    Abstract: As the 2019 novel coronavirus disease (COVID-19) continues to spread, some patients are presenting with abdominal symptoms without respiratory complaints. Our case series documents four patients who presented with abdominal symptoms whose abdominopelvic ... ...

    Abstract As the 2019 novel coronavirus disease (COVID-19) continues to spread, some patients are presenting with abdominal symptoms without respiratory complaints. Our case series documents four patients who presented with abdominal symptoms whose abdominopelvic CT revealed incidental pulmonary parenchymal findings in the imaged lung bases and were subsequently confirmed positive for COVID-19 via laboratory testing. It remains to be seen whether these patients will eventually develop respiratory symptoms. While it is possible that the patients' abdominal complaints are coincidental with CT findings, it is interesting that patients can have such extensive incidental disease in the lungs on CT without respiratory symptoms.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #401515
    Database COVID19

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  8. Article ; Online: Leveraging IR's Adaptability During COVID-19: A Multicenter Single Urban Health System Experience.

    Manna, Sayan / Voutsinas, Nicholas / Maron, Samuel Z / Cedillo, Mario A / Toussie, Danielle / Nowakowski, F Scott / Lookstein, Robert A / Fischman, Aaron

    Journal of vascular and interventional radiology : JVIR

    2020  Volume 31, Issue 7, Page(s) 1192–1194

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/therapy ; Critical Care/methods ; Humans ; Intensive Care Units ; Internship and Residency ; Medical Staff, Hospital ; New York ; Pandemics ; Pneumonia, Viral/therapy ; Radiology, Interventional ; SARS-CoV-2 ; Urban Health ; Workflow
    Keywords covid19
    Language English
    Publishing date 2020-05-03
    Publishing country United States
    Document type Letter ; Multicenter Study
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2020.04.030
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  9. Article ; Online: Barotrauma in COVID 19: Incidence, pathophysiology, and effect on prognosis.

    Steinberger, Sharon / Finkelstein, Mark / Pagano, Andrew / Manna, Sayan / Toussie, Danielle / Chung, Michael / Bernheim, Adam / Concepcion, Jose / Gupta, Sean / Eber, Corey / Dua, Sakshi / Jacobi, Adam H

    Clinical imaging

    2022  Volume 90, Page(s) 71–77

    Abstract: Objectives: To investigate the incidence, risk factors, and outcomes of barotrauma (pneumomediastinum and subcutaneous emphysema) in mechanically ventilated COVID-19 patients. To describe the chest radiography patterns of barotrauma and understand the ... ...

    Abstract Objectives: To investigate the incidence, risk factors, and outcomes of barotrauma (pneumomediastinum and subcutaneous emphysema) in mechanically ventilated COVID-19 patients. To describe the chest radiography patterns of barotrauma and understand the development in relation to mechanical ventilation and patient mortality.
    Methods: We performed a retrospective study of 363 patients with COVID-19 from March 1 to April 8, 2020. Primary outcomes were pneumomediastinum or subcutaneous emphysema with or without pneumothorax, pneumoperitoneum, or pneumoretroperitoneum. The secondary outcomes were length of intubation and death. In patients with pneumomediastinum and/or subcutaneous emphysema, we conducted an imaging review to determine the timeline of barotrauma development.
    Results: Forty three out of 363 (12%) patients developed barotrauma radiographically. The median time to development of either pneumomediastinum or subcutaneous emphysema was 2 days (IQR 1.0-4.5) after intubation and the median time to pneumothorax was 7 days (IQR 2.0-10.0). The overall incidence of pneumothorax was 28/363 (8%) with an incidence of 17/43 (40%) in the barotrauma cohort and 11/320 (3%) in those without barotrauma (p ≤ 0.001). In total, 257/363 (71%) patients died with an increase in mortality in those with barotrauma 33/43 (77%) vs. 224/320 (70%). When adjusting for covariates, barotrauma was associated with increased odds of death (OR 2.99, 95% CI 1.25-7.17).
    Conclusion: Barotrauma is a frequent complication of mechanically ventilated COVID-19 patients. In comparison to intubated COVID-19 patients without barotrauma, there is a higher rate of pneumothorax and an increased risk of death.
    MeSH term(s) Barotrauma/complications ; Barotrauma/etiology ; COVID-19/epidemiology ; Humans ; Incidence ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/epidemiology ; Mediastinal Emphysema/etiology ; Pneumothorax/diagnostic imaging ; Pneumothorax/epidemiology ; Pneumothorax/etiology ; Prognosis ; Retrospective Studies ; Subcutaneous Emphysema/diagnostic imaging ; Subcutaneous Emphysema/epidemiology ; Subcutaneous Emphysema/etiology
    Language English
    Publishing date 2022-06-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2022.06.014
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  10. Article ; Online: The right upper lobe bronchus angle: A tool for differentiating fibrotic and non-fibrotic sarcoidosis.

    Salvatore, Mary / Toussie, Danielle / Pavlishyn, Nadiya / Yankelevitz, David / O'Connor, Timothy / Henschke, Claudia / Padilla, Maria

    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG

    2020  Volume 37, Issue 2, Page(s) 99–103

    Abstract: Purpose: To evaluate the Right Upper Lobe Bronchus Angle (RUL-BA) on chest CT in patients with Stage 4 sarcoidosis and compare to others with non-fibrotic sarcoidosis.: Methods: IRB approval was obtained for review of all chest CT scans performed ... ...

    Abstract Purpose: To evaluate the Right Upper Lobe Bronchus Angle (RUL-BA) on chest CT in patients with Stage 4 sarcoidosis and compare to others with non-fibrotic sarcoidosis.
    Methods: IRB approval was obtained for review of all chest CT scans performed from January 2015 through December 2017 that contained the word sarcoidosis using the computer program Montage. The most recent CT scans of 633 people were reviewed. The patients' age and sex at the time of their most recent CT scan were recorded. The radiographic diagnosis and the Right Upper Lobe Bronchus Angle (RUL-BA) were determined by a chest radiologist with 20 years of experience.
    Results: The RUL-BA increased with Stage 4 sarcoidosis, measuring on average 104 degrees, compared to the average angle of 88 degrees for those without fibrotic sarcoid. More often men's CT scans exhibited the earlier stages of sarcoidosis, and a higher number of women's scans showed fibrotic sarcoidosis. As would be expected, scans with advanced disease were typically from older patients; however, there was no correlation between age and degree of fibrosis as measured by increasing RUL-BA.
    Conclusion: The RUL-BA assists radiologists in differentiating fibrotic sarcoidosis from non-fibrotic sarcoidosis. Further research will determine if the RUL-BA measurement can help differentiate fibrotic sarcoid from other fibrotic lung diseases and if the angle can be used to follow disease progression.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Bronchi/diagnostic imaging ; Diagnosis, Differential ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Pulmonary Fibrosis/diagnostic imaging ; Sarcoidosis, Pulmonary/diagnostic imaging ; Severity of Illness Index ; Tomography, X-Ray Computed ; Young Adult
    Language English
    Publishing date 2020-06-30
    Publishing country Italy
    Document type Comparative Study ; Journal Article
    ZDB-ID 1339192-6
    ISSN 2532-179X ; 1124-0490
    ISSN (online) 2532-179X
    ISSN 1124-0490
    DOI 10.36141/svdld.v37i2.8965
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