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Article: Innovative association network of new energy vehicle charging stations in China: Structural evolution and policy implications.

Hu, Feng / Wei, Shaobin / Qiu, Liping / Hu, Hao / Zhou, Haiyan

2024 Volume 10, Issue 2, Page(s) e24764

Abstract: New energy vehicles (NEVs) can effectively reduce emissions and alleviate global climate problems, and are crucial to global sustainable development. China is the world's largest seller of NEVs, but charging stations have always been a major constraint ... ...

Abstract	New energy vehicles (NEVs) can effectively reduce emissions and alleviate global climate problems, and are crucial to global sustainable development. China is the world's largest seller of NEVs, but charging stations have always been a major constraint to the development of NEVs. To clearly characterize the structural characteristics of an innovation association network of NEV charging stations, this study analyzes the structural characteristics of China's innovation association network of NEV charging stations with the patent data since 2007 in the Incopat Global Patent Database from the three perspectives of province, city and patent applicant using method of social network analysis (SNA). The findings show the following: (1) The innovation association network of NEV charging stations has been expanded constantly, with the association strength evidently increasing. (2) The innovation association network of NEV charging stations exhibits a typical core-periphery structure, with the quantity of nodes with high association strength varying little, and the quantity of nodes with low- and medium-association strengths exhibiting an evident increasing trend. (3) The effect of regional central cities is enhanced, with an evident group structure. There has been no information barrier caused by excessive small group formation in the province association network, whereas there are small group development trends in city and patent applicant cooperation networks. In addition, policy recommendations for further expanding technological innovation in charging stations to promote the development of the NEV industry are discussed based on the study results.
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e24764
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Comparisons of short-term and long-term results between laparoscopic between open pancreaticoduodenectomy for pancreatic tumors: A systematic review and meta-analysis.

Qiu, Hongquan / Zhang, Liang / Wang, Dongzhi / Miao, Haiyan / Zhang, Yu

Frontiers in genetics

2023 Volume 13, Page(s) 1072229

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2023-01-20
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2022.1072229
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Article: [Clinical and genetic analysis of a child with Culler-Jones syndrome due to variant of GLI2 gene].

Fan, Yanshi / Ding, Shuxia / Wu, Junhua / Qiu, Haiyan

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

2023 Volume 40, Issue 2, Page(s) 217–221

Abstract: Objective: To explore the genetic basis for a child featuring short stature and postaxial polydactyly.: Methods: A child who presented at Ningbo Women & Children's Hospital in May 2021 due to the"discovery of growth retardation for more than two ... ...

Abstract	Objective: To explore the genetic basis for a child featuring short stature and postaxial polydactyly. Methods: A child who presented at Ningbo Women & Children's Hospital in May 2021 due to the"discovery of growth retardation for more than two years" was selected as the subject. Peripheral blood samples of the child and his parents were collected for the extraction of genomic DNA. Whole exome sequencing was carried out for the child, and candidate variant was verified by Sanger sequencing of his family members. Results: The child was found to harbor a heterozygous c.3670C>T (p.Q1224) variant of the GLI2 gene, which may lead to premature termination of protein translation. The variant was not detected in either parent. Conclusion: The child was diagnosed with Culler-Jones syndrome. The c.3670C>T (p.Q1224*) variant of the GLI2 gene probably underlay the disease in this child.
MeSH term(s)	Child ; Female ; Humans ; Fingers ; Mutation ; Nuclear Proteins/genetics ; Polydactyly/genetics ; Toes ; Zinc Finger Protein Gli2/genetics
Chemical Substances	GLI2 protein, human ; Nuclear Proteins ; Zinc Finger Protein Gli2
Language	Chinese
Publishing date	2023-01-30
Publishing country	China
Document type	Case Reports ; English Abstract ; Journal Article
ISSN	1003-9406
ISSN	1003-9406
DOI	10.3760/cma.j.cn511389-20210927-00779
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Article ; Online: Generation and enhancement of the sum sideband under double radiation pressure.

Liao, Qinghong / Ao, Jiawen / Song, Menglin / Qiu, Haiyan

Optics express

2023 Volume 31, Issue 17, Page(s) 27508–27519

Abstract: A theoretical scheme to enhance the sum sideband generation (SSG) via double radiation pressure is proposed. In this scheme, both sides of the double-cavity system are driven by red and blue detuned pump lasers and frequency components are generated at ... ...

Abstract	A theoretical scheme to enhance the sum sideband generation (SSG) via double radiation pressure is proposed. In this scheme, both sides of the double-cavity system are driven by red and blue detuned pump lasers and frequency components are generated at the sum sideband through optomechanical nonlinear interaction. The results show that the efficiency of SSG can be improved with orders of magnitude. We further investigate the properties of SSG in resolved and unresolved sideband regimes. The efficiencies of upper sum sideband generation (USSG) and lower sum sideband generation (LSSG) are the equivalent in the unresolved sideband regime when the threshold condition is satisfied. It is worth noting that with the increase of the ratio between the dissipation rate of the cavity field and the decay rate of the mechanical resonator (MR), the amplitude of the LSSG can be superior to that of the USSG. Our scheme may provide a potential application in realizing the measurement of high-precision weak forces and quantum-sensitive sensing.
Language	English
Publishing date	2023-09-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.494310
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Article ; Online: Silver Nanoparticles Improve the Biocompatibility and Reduce the Immunogenicity of Xenogeneic Scaffolds Derived from Decellularized Pancreas.

Qiu, Hongquan / Zhang, Liang / Wang, Dongzhi / Miao, Haiyan

Cellular reprogramming

2022 Volume 24, Issue 1, Page(s) 38–47

Abstract: Xenogeneic scaffolds derived from the decellularized pancreas are plausible biomedical materials for pancreatic tissue engineering applications. During the decellularized process, the ultrastructure of extracellular matrices, including collagen fibers, ... ...

Abstract	Xenogeneic scaffolds derived from the decellularized pancreas are plausible biomedical materials for pancreatic tissue engineering applications. During the decellularized process, the ultrastructure of extracellular matrices, including collagen fibers, was destructed, which leads to the decrease of mechanical strength and the immune-inflammatory response after transplantation
MeSH term(s)	Animals ; Endothelial Cells ; Metal Nanoparticles/chemistry ; Pancreas ; Rats ; Rats, Sprague-Dawley ; Silver/chemistry ; Silver/pharmacology ; Tissue Engineering/methods ; Tissue Scaffolds/chemistry
Chemical Substances	Silver (3M4G523W1G)
Language	English
Publishing date	2022-02-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2542436-1
ISSN	2152-4998 ; 1557-7457 ; 2152-4971
ISSN (online)	2152-4998 ; 1557-7457
ISSN	2152-4971
DOI	10.1089/cell.2021.0071
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Article ; Online: Identification of potential biomarkers and therapeutic targets related to post-traumatic stress disorder due to traumatic brain injury.

Qi, Peng / Huang, Mengjie / Ren, Xuewen / Zhai, Yongzhi / Qiu, Chen / Zhu, Haiyan

European journal of medical research

2024 Volume 29, Issue 1, Page(s) 44

Abstract: Background: Post-traumatic stress disorder (PTSD), a disease state that has an unclear pathogenesis, imposes a substantial burden on individuals and society. Traumatic brain injury (TBI) is one of the most significant triggers of PTSD. Identifying ... ...

Abstract	Background: Post-traumatic stress disorder (PTSD), a disease state that has an unclear pathogenesis, imposes a substantial burden on individuals and society. Traumatic brain injury (TBI) is one of the most significant triggers of PTSD. Identifying biomarkers associated with TBI-related PTSD will help researchers to uncover the underlying mechanism that drives disease development. Furthermore, it remains to be confirmed whether different types of traumas share a common mechanism of action. Methods: For this study, we screened the eligible data sets from the Gene Expression Omnibus (GEO) database, obtained differentially expressed genes (DEGs) through analysis, conducted functional enrichment analysis on the DEGs in order to understand their molecular mechanisms, constructed a PPI network, used various algorithms to obtain hub genes, and finally evaluated, validated, and analyzed the diagnostic performance of the hub genes. Results: A total of 430 upregulated and 992 down-regulated differentially expressed genes were extracted from the TBI data set. A total of 1919 upregulated and 851 down-regulated differentially expressed genes were extracted from the PTSD data set. Functional enrichment analysis revealed that the differentially expressed genes had biological functions linked to molecular regulation, cell signaling transduction, cell metabolic regulation, and immune response. After constructing a PPI network and introducing algorithm analysis, the upregulated hub genes were identified as VNN1, SERPINB2, and ETFDH, and the down-regulated hub genes were identified as FLT3LG, DYRK1A, DCN, and FKBP8. In addition, by comparing the data with patients with other types of trauma, it was revealed that PTSD showed different molecular processes that are under the influence of different trauma characteristics and responses. Conclusions: By exploring the role of different types of traumas during the pathogenesis of PTSD, its possible molecular mechanisms have been revealed, providing vital information for understanding the complex pathways associated with TBI-related PTSD. The data in this study has important implications for the design and development of new diagnostic and therapeutic methods needed to treat and manage PTSD.
MeSH term(s)	Humans ; Stress Disorders, Post-Traumatic/genetics ; Gene Expression Profiling/methods ; Biomarkers/metabolism ; Algorithms ; Brain Injuries, Traumatic/genetics ; Computational Biology/methods
Chemical Substances	Biomarkers
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1329381-3
ISSN	2047-783X ; 0949-2321
ISSN (online)	2047-783X
ISSN	0949-2321
DOI	10.1186/s40001-024-01640-x
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Zs.A 4636: Show issues

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Article: Association between weight-adjusted waist index and serum total testosterone in males aged 6-19 years in the United States: Data from NHANES 2013-2016.

Wu, Zhifei / Bao, Lingling / Wang, Haiyan / Zheng, Jiajing / Chen, Yu / Wang, Wenjuan / Qiu, Dongkai

Heliyon

2024 Volume 10, Issue 6, Page(s) e27520

Abstract: Objective: This study aimed to estimate the association between weight-adjusted waist index and serum total testosterone (sTT) in males aged 6-19 years in the United States.: Methods: A cross-sectional study was conducted using data from the National ...

Abstract	Objective: This study aimed to estimate the association between weight-adjusted waist index and serum total testosterone (sTT) in males aged 6-19 years in the United States. Methods: A cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (NHANES) 2013-2016. sTT was considered as the response variable, and weight-adjusted waist circumference index (WWI) as the independent variable. Multiple linear regression was performed to estimate the association between the two variables, and subgroup analysis was performed to identify sensitive cohorts. Smoothing curve fitting and threshold effects analysis was carried out to assess possible nonlinear relationships between WWI and sTT. Results: The study included 4207 participants. The mean value of sTT (117.93 ng/dl) was used as the grouping basis, with 1066 participants having serum total testosterone levels above the mean. A negative association was observed between WWI and sTT [beta coefficient (β) = -72.50, 95% confidence interval (CI): -79.45, -65.55], which decreased as WWI increased (P for trend<0.05). Subgroup analysis indicated a stronger negative correlation in late adolescent (16-19 years) males (β = -128.94, 95% CI: -146.75, -111.13). The smoothing curve fit analysis revealed a U-shaped curve relationship for the negative correlation between WWI and sTT. Threshold effect analysis suggested a significant change when WWI exceeded 10.09 (β = -15.82, 95% CI: -24.11, -7.54), and stepwise threshold effect analysis indicated that this negative correlation became less stable when WWI exceeded 11.45 (β = -0.80, 95% CI: -9.15, 7.56). Conclusions: Participants with higher WWI exhibited lower total testosterone levels, and a negative association was found between WWI and total testosterone, particularly in late adolescent males aged 16-19 years. Among males aged 6-19 years, caution should be exercised regarding the risk of lower testosterone levels associated with elevated WWI, particularly when WWI is below 10.09.
Language	English
Publishing date	2024-03-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e27520
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Article ; Online: Identification of potential biomarkers and therapeutic targets related to post-traumatic stress disorder due to traumatic brain injury

Peng Qi / Mengjie Huang / Xuewen Ren / Yongzhi Zhai / Chen Qiu / Haiyan Zhu

European Journal of Medical Research, Vol 29, Iss 1, Pp 1-

2024 Volume 13

Abstract: Abstract Background Post-traumatic stress disorder (PTSD), a disease state that has an unclear pathogenesis, imposes a substantial burden on individuals and society. Traumatic brain injury (TBI) is one of the most significant triggers of PTSD. ... ...

Abstract	Abstract Background Post-traumatic stress disorder (PTSD), a disease state that has an unclear pathogenesis, imposes a substantial burden on individuals and society. Traumatic brain injury (TBI) is one of the most significant triggers of PTSD. Identifying biomarkers associated with TBI-related PTSD will help researchers to uncover the underlying mechanism that drives disease development. Furthermore, it remains to be confirmed whether different types of traumas share a common mechanism of action. Methods For this study, we screened the eligible data sets from the Gene Expression Omnibus (GEO) database, obtained differentially expressed genes (DEGs) through analysis, conducted functional enrichment analysis on the DEGs in order to understand their molecular mechanisms, constructed a PPI network, used various algorithms to obtain hub genes, and finally evaluated, validated, and analyzed the diagnostic performance of the hub genes. Results A total of 430 upregulated and 992 down-regulated differentially expressed genes were extracted from the TBI data set. A total of 1919 upregulated and 851 down-regulated differentially expressed genes were extracted from the PTSD data set. Functional enrichment analysis revealed that the differentially expressed genes had biological functions linked to molecular regulation, cell signaling transduction, cell metabolic regulation, and immune response. After constructing a PPI network and introducing algorithm analysis, the upregulated hub genes were identified as VNN1, SERPINB2, and ETFDH, and the down-regulated hub genes were identified as FLT3LG, DYRK1A, DCN, and FKBP8. In addition, by comparing the data with patients with other types of trauma, it was revealed that PTSD showed different molecular processes that are under the influence of different trauma characteristics and responses. Conclusions By exploring the role of different types of traumas during the pathogenesis of PTSD, its possible molecular mechanisms have been revealed, providing vital information for understanding ...
Keywords	Traumatic brain injury ; Post-traumatic stress disorder ; Bioinformatic analysis ; Differentially expressed genes ; Biomarker ; Medicine ; R
Subject code	150
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Rewiring carbon flow in

Gao, E-Bin / Wu, Junhua / Ye, Penglin / Qiu, Haiyan / Chen, Huayou / Fang, Zhen

Frontiers in microbiology

2023 Volume 14, Page(s) 1211004

Abstract: Cyanobacteria are an excellent microbial photosynthetic platform for sustainable carbon dioxide fixation. One bottleneck to limit its application is that the natural carbon flow pathway almost transfers ... ...

Abstract	Cyanobacteria are an excellent microbial photosynthetic platform for sustainable carbon dioxide fixation. One bottleneck to limit its application is that the natural carbon flow pathway almost transfers CO
Language	English
Publishing date	2023-05-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1211004
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Article: Contrasting patterns of genetic and phenotypic divergence of two sympatric congeners,

Qiu, Tian / Liu, Zhiyuan / Li, Haiyan / Yang, Ji / Liu, Bao / Yang, Yunfei

Frontiers in plant science

2023 Volume 14, Page(s) 1299128

Abstract: Habitat heterogeneity leads to genome-wide differentiation and morphological and ecological differentiation, which will progress along the speciation continuum, eventually leading to speciation. ...

Abstract	Habitat heterogeneity leads to genome-wide differentiation and morphological and ecological differentiation, which will progress along the speciation continuum, eventually leading to speciation.
Language	English
Publishing date	2023-12-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1299128
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