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  1. Book ; Online: Aux marges de l'hérésie

    Mercier, Franck / Rosé, Isabelle / Rosé, Isabelle

    Inventions, formes et usages polémiques de l'accusation d'hérésie au Moyen Âge

    (Histoire)

    2018  

    Series title Histoire
    Keywords Early history: c 500 to c 1450/1500 ; Histoire médiévale ; Histoire religieuse
    Language fra
    Size 1 electronic resource (380 pages)
    Publisher Presses universitaires de Rennes
    Publishing place Rennes
    Document type Book ; Online
    Note French
    HBZ-ID HT030375001
    ISBN 9782753559042 ; 275355904X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Caveolins in cancer pathogenesis, prevention and therapy

    Mercier, Isabelle

    (Current cancer research)

    2012  

    Author's details Isabelle Mercier ed
    Series title Current cancer research
    Language English
    Size XI, 123 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017059893
    ISBN 978-1-4614-1000-3 ; 9781461410010 ; 1-4614-1000-2 ; 1461410010
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 5221 order for loan Magazin

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  3. Article ; Online: Reliability of an observation-based scoring grid to assess bimanual performance during unstandardized tasks in adults living with cerebral palsy.

    Gagné-Pelletier, Léandre / Poitras, Isabelle / Flamand, Véronique H / Mercier, Catherine

    Disability and rehabilitation

    2023  , Page(s) 1–6

    Abstract: Purpose: Most activities of daily living (ADLs) require the use of both upper extremities. However, few assessments exist to assess bimanual performance, especially among adults living with cerebral palsy (CP). The aim of this preliminary study is to ... ...

    Abstract Purpose: Most activities of daily living (ADLs) require the use of both upper extremities. However, few assessments exist to assess bimanual performance, especially among adults living with cerebral palsy (CP). The aim of this preliminary study is to assess the interrater reliability and convergent validity of the Assisting Hand Assessment (AHA) scoring grid applied to unstandardized ADLs.
    Materials and methods: For this validation study, nineteen adults living with spastic unilateral CP were videotaped performing seven bimanual ADLs. Three raters assessed the videos independently using the 20-item grid of the AHA. Gwet's AC2 was used to assess interrater reliability. Kendall's Tau-b correlation was used between the observation-based scoring grid and Jebsen-Taylor Hand Function Test (JTHFT) scores to assess convergent validity.
    Results: Interrater reliability was good (0.84, SD = 0.02). The correlation with the JTHFT was high (τb = -0.74;
    Conclusion: The results show the potential of using an observation-based scoring grid with unstandardized ADLs to assess bimanual performance in adults living with CP, but further research on psychometric properties is needed. This method allows for an assessment that is occupation-oriented, ecological, and meaningful.
    Language English
    Publishing date 2023-09-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104775-6
    ISSN 1464-5165 ; 0963-8288
    ISSN (online) 1464-5165
    ISSN 0963-8288
    DOI 10.1080/09638288.2023.2254700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1569: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Assembling the Current Pieces: The Puzzle of RNA-Mediated Regulation in

    Barrientos, Laura / Mercier, Noémie / Lalaouna, David / Caldelari, Isabelle

    Frontiers in microbiology

    2021  Volume 12, Page(s) 706690

    Abstract: The success of the major opportunistic ... ...

    Abstract The success of the major opportunistic human
    Language English
    Publishing date 2021-07-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.706690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Optimizing Epoch Length and Activity Count Threshold Parameters in Accelerometry: Enhancing Upper Extremity Use Quantification in Cerebral Palsy.

    Poitras, Isabelle / Gagné-Pelletier, Léandre / Clouâtre, Jade / Flamand, Véronique H / Campeau-Lecours, Alexandre / Mercier, Catherine

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 4

    Abstract: Various accelerometry protocols have been used to quantify upper extremity (UE) activity, encompassing diverse epoch lengths and thresholding methods. However, there is no consensus on the most effective approach. The aim of this study was to delineate ... ...

    Abstract Various accelerometry protocols have been used to quantify upper extremity (UE) activity, encompassing diverse epoch lengths and thresholding methods. However, there is no consensus on the most effective approach. The aim of this study was to delineate the optimal parameters for analyzing accelerometry data to quantify UE use in individuals with unilateral cerebral palsy (CP).
    Methods: A group of adults with CP (
    Results: In adults, results are comparable across epoch lengths, with the best
    Conclusions: The combination of epoch length and
    MeSH term(s) Child ; Adult ; Humans ; Cerebral Palsy ; Activities of Daily Living ; Upper Extremity ; Accelerometry/methods ; Wrist
    Language English
    Publishing date 2024-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24041100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Reproducibility in PD-L1 Immunohistochemistry Quantification through the Tumor Proportion Score and the Combined Positive Score: Could Dual Immunostaining Help Pathologists?

    Mercier, Anaïs / Conan-Charlet, Virginie / Quintin-Roué, Isabelle / Doucet, Laurent / Marcorelles, Pascale / Uguen, Arnaud

    Cancers

    2023  Volume 15, Issue 10

    Abstract: We studied the pathologists' agreements in quantifying PD-L1 expression through the tumor proportion score (TPS) and the combined positive score (CPS) using single PD-L1 immunohistochemistry (S-IHC) and double immunohistochemistry (D-IHC) combining PD-L1 ...

    Abstract We studied the pathologists' agreements in quantifying PD-L1 expression through the tumor proportion score (TPS) and the combined positive score (CPS) using single PD-L1 immunohistochemistry (S-IHC) and double immunohistochemistry (D-IHC) combining PD-L1 staining and tumor cell markers. S-IHC and D-IHC were applied to 15 cancer samples to generate 60 digital IHC slides (30 whole slides images and 30 regions of interest of 1 mm
    Language English
    Publishing date 2023-05-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15102768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A six-participant pilot single-subject study of an individualized pain management program for people with spinal cord injury.

    Proulx, Ketsia / Lamontagne, Marie-Eve / Quirion, René / Deaudelin, Isabelle / Mercier, Catherine / Perreault, Kadija

    Spinal cord series and cases

    2023  Volume 9, Issue 1, Page(s) 2

    Abstract: Study design: Single-subject repeated measures design.: Objectives: To explore the impacts of a novel individualized interdisciplinary pain self-management program for persons living with spinal cord injury pain.: Setting: A large rehabilitation ... ...

    Abstract Study design: Single-subject repeated measures design.
    Objectives: To explore the impacts of a novel individualized interdisciplinary pain self-management program for persons living with spinal cord injury pain.
    Setting: A large rehabilitation institute for adults with physical disabilities in Quebec city (Quebec, Canada).
    Methods: Six persons having sustained a spinal cord injury and experiencing chronic pain participated. Following a five-week pre-intervention phase (baseline repeated measures) and a clinical evaluation, individualized intervention objectives were developed in collaboration with each participant. Then, participants completed a ten-week intensive intervention and a six-month consolidation phase. The program included cognitive behavioral therapy, and physical and pharmacological interventions, which were group- and individual-based. Outcome measures were the Canadian Occupational Performance Measure (COPM), the French-Canadian Chronic Pain Self-efficacy Scale (FC-CPSES), the Brief Pain Inventory (BPI), and the Hospital Anxiety and Depression Scale (HADS).
    Results: For five out of the six participants, a majority of outcomes improved during either of the intervention phases or both. Improvements in occupational performance were clinically significant for three participants. Pain interference and anxiety improved significantly in five participants, while pain self-efficacy and depressive symptoms improved in four participants.
    Conclusions: The results suggest that the pain self-management program was effective to reduce the impact of spinal cord injury pain. Further research is needed to replicate these results in a larger study and comprehend the factors favoring or undermining improvements with such programs, as well as their persistence over time.
    MeSH term(s) Adult ; Humans ; Pain Management/methods ; Chronic Pain/therapy ; Canada ; Cognitive Behavioral Therapy/methods ; Spinal Cord Injuries/rehabilitation
    Language English
    Publishing date 2023-01-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2058-6124
    ISSN (online) 2058-6124
    DOI 10.1038/s41394-022-00557-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  8. Article ; Online: Brief Report: A Multidisciplinary Initial Workup for Suspected Lung Cancer as Fast-Track Intervention to Histopathologic Diagnosis.

    Pujol, Jean-Louis / Mercier, Grégoire / Vasile, Maria / Serre, Isabelle / Vernhet-Kovacsik, Hélène / Bommart, Sébastien

    JTO clinical and research reports

    2023  Volume 4, Issue 6, Page(s) 100526

    Abstract: Guidelines for optimal timing of lung cancer diagnosis and treatment have been implemented in many countries, but the effect of fast-track interventions on the shortening of time interval is still debatable. In this study, the delay from the first ... ...

    Abstract Guidelines for optimal timing of lung cancer diagnosis and treatment have been implemented in many countries, but the effect of fast-track interventions on the shortening of time interval is still debatable. In this study, the delay from the first specialist visit to the histopathologic diagnosis was compared between two patient cohorts: before (n = 280) and after (n = 247) implementation of a fast-track multidisciplinary diagnosis program. The cumulative incidence function curves were compared, and hazard ratio was adjusted in the Cox model. The implementation allowed a statistically significant increase in the cumulative incidence of the lung cancer histopathologic diagnosis over time. Adjusted hazard ratio for patients accrued in the post-implementation cohort was 1.22 (1.03-1.45) (
    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3643
    ISSN (online) 2666-3643
    DOI 10.1016/j.jtocrr.2023.100526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Influence of Perioperative Factors on Patency After Endovascular and Hybrid Treatments of TASC II D Aortoiliac Occlusive Lesions.

    Kriens, Myriam / Jayet, Jérémie / Gallien, Yves / Mercier, Lucie / Javerliat, Isabelle / Coggia, Marc / Coscas, Raphaël

    Annals of vascular surgery

    2023  Volume 99, Page(s) 252–261

    Abstract: Background: Treatment of Trans-Atlantic Inter-Society Consensus (TASC) II D aortoiliac occlusive disease (AIOD D) remains a controversial topic. Although current recommendations support conventional surgical treatment, several recent studies have ... ...

    Abstract Background: Treatment of Trans-Atlantic Inter-Society Consensus (TASC) II D aortoiliac occlusive disease (AIOD D) remains a controversial topic. Although current recommendations support conventional surgical treatment, several recent studies have reported promising results with endovascular and hybrid strategies. The purpose of this work was to describe the outcomes of endovascular and hybrid management of AIOD D and to investigate the influence of perioperative factors on patency.
    Methods: This was a retrospective single-center study covering the period from 2016 to 2021. The primary end point was primary patency at 12 months. Secondary endpoints included technical success rate, 30-day mortality, early major complication rate, primary assisted and secondary patency at 12 months, and primary patency at 24 months. After descriptive statistical analysis, a survival analysis was conducted using the Kaplan-Meier method. Eighteen perioperative factors potentially associated with primary patency were studied by univariate and multivariate analysis adjusted by a Cox regression model.
    Results: In all, 82 patients (112 limbs) had undergone an attempt at endovascular (n = 55, 67%) or hybrid (n = 27, 33%) treatment for AIOD D over the study period. The technical success rate was 99%. The 30-day mortality rate was 3%. The early major complication rate was 11%. The primary patency rates at 12 and 24 months were 87.9% [80.3; 96.3] and 77% [66.3; 89.3], respectively. The primary assisted and secondary patency rates at 12 months were 92.6% [86.3; 99.2] and 96% [91.4; 100]. Among the perioperative factors studied, the heavily calcified nature of the target lesions was the only variable significantly associated with primary patency loss in the multivariate analysis (P = 0.021).
    Conclusion: Although the results of endovascular and hybrid treatment of AOID D are acceptable, future studies should focus on improving patency rates in heavily calcified lesions. Specific tools of endovascular preparation (intravascular lithotripsy, atherectomy) may represent interesting ways of research.
    MeSH term(s) Humans ; Arterial Occlusive Diseases/diagnostic imaging ; Arterial Occlusive Diseases/surgery ; Risk Factors ; Retrospective Studies ; Consensus ; Endovascular Procedures ; Treatment Outcome ; Vascular Patency ; Iliac Artery/diagnostic imaging ; Iliac Artery/surgery ; Atherosclerosis ; Stents
    Language English
    Publishing date 2023-10-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2023.08.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2882: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Accelerometry-Based Metrics to Evaluate the Relative Use of the More Affected Arm during Daily Activities in Adults Living with Cerebral Palsy.

    Poitras, Isabelle / Clouâtre, Jade / Campeau-Lecours, Alexandre / Mercier, Catherine

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 3

    Abstract: Adults living with cerebral palsy (CP) report bimanual and unimanual difficulties that interfere with their participation in activities of daily living (ADL). There is a lack of quantitative methods to assess the impact of these motor dysfunctions on the ...

    Abstract Adults living with cerebral palsy (CP) report bimanual and unimanual difficulties that interfere with their participation in activities of daily living (ADL). There is a lack of quantitative methods to assess the impact of these motor dysfunctions on the relative use of each arm. The objective of this study was to evaluate the concurrent and discriminative validity of accelerometry-based metrics when used to assess bimanual and unimanual functions.
    Methods: A group of control subjects and hemiplegic adults living with CP performed six ADL tasks, during which they were wearing an Actigraph GT9X on each wrist and being filmed. Four bimanual and unimanual metrics were calculated from both accelerometry-based and video-based data; these metrics were then compared to one other with an intraclass correlation coefficient (ICC). Some of these metrics were previously validated in other clinical population, while others were novel. The discriminative validity was assessed through comparisons between groups and between tasks.
    Results: The concurrent validity was considered as good to excellent (ICC = 0.61-0.97) depending on the experience of the raters. The tasks made it possible to discriminate between groups.
    Conclusion: The proposed accelerometry-based metrics are a promising tool to evaluate bimanual and unimanual functions in adults living with CP.
    MeSH term(s) Accelerometry ; Activities of Daily Living ; Adult ; Arm ; Benchmarking ; Cerebral Palsy/diagnosis ; Humans ; Upper Extremity
    Language English
    Publishing date 2022-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22031022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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