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  1. Article ; Online: Adaptive robust structure exploration for complex systems based on model configuration and fusion.

    Qu, Yingfei / Liu, Wanbing / Wen, Junhao / Li, Ming

    PeerJ. Computer science

    2024  Volume 10, Page(s) e1983

    Abstract: Analyzing and obtaining useful information is challenging when facing a new complex system. Traditional methods often focus on specific structural aspects, such as communities, which may overlook the important features and result in biased conclusions. ... ...

    Abstract Analyzing and obtaining useful information is challenging when facing a new complex system. Traditional methods often focus on specific structural aspects, such as communities, which may overlook the important features and result in biased conclusions. To address this, this article suggests an adaptive algorithm for exploring complex system structures using a generative model. This method calculates and optimizes node parameters, which can reflect the latent structural characteristics of the complex system. The effectiveness and stability of this method have been demonstrated in comparative experiments on 10 sets of benchmark networks using our model parameter configuration scheme. To enhance adaptability, algorithm fusion strategies were also proposed and tested on two real-world networks. The results indicate that the algorithm can uncover multiple structural features, including clustering, overlapping, and local chaining. This adaptive algorithm provides a promising approach for exploring complex system structures.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Model and Property Analysis for a Ball-Hinged Three-Degree-of-Freedom Piezoelectric Spherical Motor.

    Wang, Zhenyu / Li, Jun / Liu, Wanbing / Jia, Guanshuai / Wang, Ban

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 5

    Abstract: Multi-degree-of-freedom piezoelectric motors have the advantages of high torque and resolution, simple structure, and direct drive, which are widely used in robot wrist joints, deep-sea mechanisms, medical equipment, and space mechanisms. To solve the ... ...

    Abstract Multi-degree-of-freedom piezoelectric motors have the advantages of high torque and resolution, simple structure, and direct drive, which are widely used in robot wrist joints, deep-sea mechanisms, medical equipment, and space mechanisms. To solve the problems of high force/torque coupling degree and ball low stator and rotor bonding strength of the traditional traveling wave type three-degree-of-freedom piezoelectric spherical motor, a new structure of ball-hinged piezoelectric spherical motor is proposed. Through coordinate transformation and force analysis, the driven mathematical model of the spherical motor is given. The model shows that the three degrees of freedom of the motor are coupled with each other. According to the mathematical model of the spherical motor, the mechanical properties of the motor are analyzed by the computer simulation. The results show that the stalling torque coefficient
    Language English
    Publishing date 2024-02-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24051470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Microbial phenolic metabolites 3-(3′,4′-dihydroxyphenyl)propanoic acid and 3′,4′-dihydroxyphenylacetic acid prevent obesity in mice fed with high-fat diet

    Chen, Wanbing / Liu, Ruonan / Zhu, Xiaoling / Lu, Qun / Yang, Hong / Liu, Rui

    Food Science and Human Wellness. 2024 Jan., v. 13, no. 1 p.327-338

    2024  

    Abstract: Obesity is associated with numerous metabolic disorders, and dietary polyphenols have been confirmed to have beneficial effects on the metabolism in obesity. However, the effect of 3-(3′,4′-dihydroxyphenyl)propanoic acid (DHPA) and 3′,4′- ... ...

    Abstract Obesity is associated with numerous metabolic disorders, and dietary polyphenols have been confirmed to have beneficial effects on the metabolism in obesity. However, the effect of 3-(3′,4′-dihydroxyphenyl)propanoic acid (DHPA) and 3′,4′-dihydroxyphenylacetic acid (DHAA), two main metabolites of dietary polyphenols, on obesity remains poorly understood. In this study, DHPA and DHAA were found to alleviate obesity, as well as regulate insulin resistance, lipid metabolism, and oxidative stress response in high-fat diet (HFD) mice. Surprisingly, the 16S rRNA sequencing and UHPLC-Q-TOF/MS demonstrated that DHPA and DHAA only slightly disturbed the intestinal microbiome, but significantly altered the urine metabolome of HFD mice mainly by regulating pentose and glucuronate interconversion, tyrosine metabolism, pentose phosphate and tricarboxylic acid (TCA) cycle as indicated by metabolic pathway analysis based on Kyoto Encyclopedia of Genes and Genomes (KEGG) database. Correlation analysis revealed that the differential metabolites are strongly associated with body weight, blood glucose, insulin level, and superoxide dismutase (SOD) enzyme activity. Our results revealed that DHPA and DHAA exert their anti-obesity effect by regulating important metabolites in the glucose, lipid and tyrosine metabolism pathways.
    Keywords anti-obesity effects ; biochemical pathways ; blood glucose ; databases ; enzyme activity ; food science ; genome ; glucose ; high fat diet ; humans ; insulin ; insulin resistance ; intestinal microorganisms ; lipid metabolism ; lipids ; metabolites ; metabolome ; obesity ; oxidative stress ; pentoses ; phosphates ; polyphenols ; propionic acid ; stress response ; superoxide dismutase ; tyrosine ; urine ; Dietary polyphenol metabolites ; Gut microbiota ; Metabonomics
    Language English
    Dates of publication 2024-01
    Size p. 327-338.
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 2712869-6
    ISSN 2213-4530
    ISSN 2213-4530
    DOI 10.26599/FSHW.2022.9250027
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Effect of valve leaflet surface patterning on valve hydrodynamic performance.

    Wang, Aili / Wang, Yumiao / Liu, Wanbing / Liu, Li / Zhou, Jianye

    The International journal of artificial organs

    2023  Volume 46, Issue 10-11, Page(s) 569–573

    Abstract: Objective: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.: Methods: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ... ...

    Abstract Objective: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance.
    Methods: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test.
    Results: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased.
    Conclusion: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.
    MeSH term(s) Hydrodynamics ; Heart Valve Prosthesis ; Hemodynamics ; Prosthesis Design ; Bioprosthesis ; Aortic Valve
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80456-3
    ISSN 1724-6040 ; 0391-3988
    ISSN (online) 1724-6040
    ISSN 0391-3988
    DOI 10.1177/03913988231192118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A newly isolated intestinal bacterium involved in the C-ring cleavage of flavan-3-ol monomers and the antioxidant activity of the metabolites.

    Wang, Li / Liu, Ruonan / Yan, Fangfang / Chen, Wanbing / Zhang, Mo / Lu, Qun / Huang, Bijun / Liu, Rui

    Food & function

    2024  Volume 15, Issue 2, Page(s) 580–590

    Abstract: Flavan-3-ols are an important class of secondary metabolites in many plants. Their bioavailability and bioactivity are largely determined by the metabolism of intestinal microbiota. However, little is known about the intestinal bacteria involved in the ... ...

    Abstract Flavan-3-ols are an important class of secondary metabolites in many plants. Their bioavailability and bioactivity are largely determined by the metabolism of intestinal microbiota. However, little is known about the intestinal bacteria involved in the metabolism of flavan-3-ols and the activities of the metabolites. C-ring cleavage is the initial and key step in the metabolism of flavan-3-ol monomers. Here, we isolated a strain from porcine cecum content, which is capable of cleaving the heterocyclic C-ring to form 1-(3',4'-dihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl)propan-2-ol from (+)-catechin and (-)-epicatechin, and 1-(3',4',5'-trihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl) propan-2-ol from (-)-epigallocatechin. The strain was identified as
    MeSH term(s) Animals ; Swine ; Catechin/pharmacology ; Catechin/metabolism ; Intestines/microbiology ; Antioxidants/pharmacology ; Flavonoids/pharmacology ; Flavonoids/metabolism
    Chemical Substances flavan-3-ol (35HDD3NRIE) ; Catechin (8R1V1STN48) ; Antioxidants ; Flavonoids
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo03601d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An examination of Wuhan City healthcare personnel afflicted with SARS-CoV-2 Omicron variants between December 15, 2022, and January 5, 2023, during the rapid Omicron outbreak in China.

    He, Yingyu / Huang, Yuan / Zhang, Fang / Zheng, Shangen / Liu, Wanbing / Liu, Lei

    Journal of infection in developing countries

    2023  Volume 17, Issue 11, Page(s) 1518–1521

    Language English
    Publishing date 2023-11-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.18050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The cyclic AMP receptor protein (CRP) controls expression of the ferric uptake regulator (Fur) in

    Liu, Lei / Liu, Wanbing / He, Yingyu / Liu, Yan / Zhang, Yiquan

    Canadian journal of microbiology

    2022  Volume 68, Issue 7, Page(s) 501–506

    Abstract: ... Yersinia ... ...

    Abstract Yersinia pestis
    MeSH term(s) Bacterial Proteins/metabolism ; Cyclic AMP Receptor Protein/genetics ; Cyclic AMP Receptor Protein/metabolism ; Gene Expression Regulation, Bacterial ; Promoter Regions, Genetic ; Yersinia pestis/genetics ; Yersinia pestis/metabolism
    Chemical Substances Bacterial Proteins ; Cyclic AMP Receptor Protein
    Language English
    Publishing date 2022-07-08
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 280534-0
    ISSN 1480-3275 ; 0008-4166
    ISSN (online) 1480-3275
    ISSN 0008-4166
    DOI 10.1139/cjm-2021-0314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transcriptional Regulation of hmsB, A Temperature-Dependent Small RNA, by RovM in Yersinia pestis Biovar Microtus.

    Liu, Lei / Liu, Wanbing / He, Yingyu / Liu, Yan / Wu, Haisheng / Zhang, Yiquan / Zhang, Qinwen

    Current microbiology

    2023  Volume 80, Issue 5, Page(s) 182

    Abstract: HmsB, a temperature-dependent sRNA, promotes biofilm formation by Yersinia pestis, but whether its own expression is regulated by other regulators is still poorly understood. RovM is a global regulator that activates biofilm formation but represses the ... ...

    Abstract HmsB, a temperature-dependent sRNA, promotes biofilm formation by Yersinia pestis, but whether its own expression is regulated by other regulators is still poorly understood. RovM is a global regulator that activates biofilm formation but represses the virulence of Y. pestis. In this work, the results of primer extension, quantitative real-time PCR (qRT-PCR), and LacZ fusion demonstrated that RovM was able to activate hmsB expression. However, the results of electrophoretic mobility shift assay (EMSA) showed that His-RovM did not bind to the upstream DNA region of hmsB. Thus, RovM may exert its regulatory action on hmsB expression in an indirect manner. The data presented here enriched the content of the regulatory circuits that control gene expression in Y. pestis.
    MeSH term(s) Animals ; Yersinia pestis/genetics ; RNA ; Arvicolinae ; Temperature ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial
    Chemical Substances RNA (63231-63-0) ; Bacterial Proteins
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 134238-1
    ISSN 1432-0991 ; 0343-8651
    ISSN (online) 1432-0991
    ISSN 0343-8651
    DOI 10.1007/s00284-023-03293-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies.

    Zhao, Wanbing / Liu, Kaien / Fan, Yun / Zhao, Qinyue / Tao, Youqi / Zhang, Mengwei / Gan, Linhua / Yu, Wenbo / Sun, Bo / Li, Dan / Liu, Cong / Wang, Jian

    Cell discovery

    2024  Volume 10, Issue 1, Page(s) 27

    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Letter
    ISSN 2056-5968
    ISSN 2056-5968
    DOI 10.1038/s41421-023-00637-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Data-Driven Optimal Formation Control for Quadrotor Team With Unknown Dynamics.

    Zhao, Wanbing / Liu, Hao / Lewis, Frank L / Wang, Xinlong

    IEEE transactions on cybernetics

    2022  Volume 52, Issue 8, Page(s) 7889–7898

    Abstract: In this article, the data-driven optimal formation control problem is addressed for a heterogeneous quadrotor team with a virtual leader. Each quadrotor is considered as a highly nonlinear system with six degrees of freedom and the accurate dynamic ... ...

    Abstract In this article, the data-driven optimal formation control problem is addressed for a heterogeneous quadrotor team with a virtual leader. Each quadrotor is considered as a highly nonlinear system with six degrees of freedom and the accurate dynamic information of the quadrotor is difficult to obtain in practical applications. An optimal cascade formation controller, including a position controller and an attitude controller, is proposed to track a virtual leader and form a predesigned formation. By using the reinforcement learning (RL) approach, the optimal formation controller is learned from the quadrotor system data without any knowledge of dynamic information of the quadrotors. Simulation results of a heterogeneous multiquadrotor system in a formation flight are given to show the effectiveness of the proposed controllers.
    Language English
    Publishing date 2022-07-19
    Publishing country United States
    Document type Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2021.3049486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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