LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 46445

Search options

  1. Article ; Online: Integrated Brain Metabolomics and Network Pharmacology Analysis to Reveal the Improvement Effect of Bai Chan Ting on Parkinson's Disease.

    Zhang, Na / Fu, Jiaqi / Gao, Xin / Lu, Fang / Lu, Yi / Liu, Shumin

    BioMed research international

    2022  Volume 2022, Page(s) 6113093

    Abstract: Background: Baichanting (BCT),a traditional Chinese medicine prescription, is a combination of : Materials and methods: By integrating network pharmacology with metabolomic research, the protective effect of BCT against PD was investigated using a ... ...

    Abstract Background: Baichanting (BCT),a traditional Chinese medicine prescription, is a combination of
    Materials and methods: By integrating network pharmacology with metabolomic research, the protective effect of BCT against PD was investigated using a transgenic mouse model for
    Results: 101 putative target genes were identified by the network pharmacology analysis in relation to the treatment of PD with BCT. According to the functional enrichment analysis, the proposed mechanism was primarily related to the transport of neurotransmitters, the metabolism of arachidonic acid, dopamine, and alpha-amino acids, as well as the transport of dopamine and the negative regulation of amino acid transport. 25 distinct endogenous metabolites were shown to be potential biomarkers for the BCT for treating PD based on metabolomics. These metabolites were mostly implicated in the important methionine and cysteine, tyrosine, histidine, and arginine and proline metabolic pathways. These results somewhat agreed with those of the network pharmacology analysis.
    Conclusions: In conclusion, this study showed that BCT could delay the occurrence and development of PD by improving the brain metabolic disorder of
    Language English
    Publishing date 2022-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2022/6113093
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Online: Ferri-chiral compounds with potentially switchable Dresselhaus spin split-ting

    Huang, Pu / Xia, Zhiguo / Gao, Xiaoqing / Rondinelli, James M. / Zhang, Xiuwen / Zhang, Han / Poeppelmeier, Kenneth R. / Zunger, Alex

    2020  

    Abstract: Spin splitting of energy bands can be induced by relativistic spin-orbit interactions in materials without inversion symmetry. Whereas polar space group symmetries permit Rashba (R-1) spin splitting with helical spin textures in momentum space, which ... ...

    Abstract Spin splitting of energy bands can be induced by relativistic spin-orbit interactions in materials without inversion symmetry. Whereas polar space group symmetries permit Rashba (R-1) spin splitting with helical spin textures in momentum space, which could be reversed upon switching a ferroelectric polarization via applied electric fields, the ordinary Dresselhaus effect (D-1A) is ac-tive only in materials exhibiting nonpolar noncentrosymmetric crystal classes with atoms occupy-ing exclusively non-polar lattice sites. Consequently, the spin-momentum locking induced by D-1A is not electric field-switchable. An alternative type of Dresselhaus symmetry, referred to as D-1B, exhibits crystal class constraints similar to D-1A (all dipoles add up to zero), but unlike D-1A, at least one polar site is occupied. We find that this behavior exists in a class of ferri-chiral crys-tals, which in principle could be reversed upon a change in chirality. Focusing on alkali metal chalcogenides, we identify NaCu5S3 in the nonentiamorphic ferri-chiral structure, which exhibits CuS3 chiral units differing in the magnitude of their Cu displacements. We then synthesize NaCu5S3 (space group P6322) and confirm its ferri-chiral structure with power x-ray diffraction. Our electronic structure calculations demonstrate it exhibits D-1B spin splitting as well as a ferri-chiral phase transition, revealing spin splitting interdependent on chirality. Our electronic struc-ture calculations show that a few percent biaxial tensile strain can reduce (or nearly quench) the switching barrier separating the monodomain ferri-chiral P6322 states. We discuss what type of external stimuli might switch the chirality so as to reverse the (non-helical) Dresselhaus D-1B spin texture, offering an alternative to the traditional reversal of the (helical) Rashba spin texture.

    Comment: 27 pages, 12 figures
    Keywords Condensed Matter - Materials Science
    Subject code 539
    Publishing date 2020-07-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: [The establishment of Ting Hsien Experimental Project of Rural Health Service and its influence].

    Zhang, Q N / Liao, S S / Zhang, K L

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2016  Volume 46, Issue 4, Page(s) 221–228

    Abstract: ... College(PUMC), the Ting Hsien Experimental Project was a demonstration program ...

    Abstract Founded by the Chinese Mass Education Movement (MEM) led by Dr.James Yen and Peking Union Medical College(PUMC), the Ting Hsien Experimental Project was a demonstration program for health service in a rural county. Through a 8-year endeavor (1929-1937) and using a bottom-up approach, Dr. Chen Chih-chien and Dr.YaoHsun-yuan took the leadership of a group of dedicated PUMC graduates and students, and created a three-level(village-district-county) system to deliver both curative as well as preventive medical service for rural population. This project, under the full support of MEM and Dr. John Black Grant, Director of the Department of Public Health of PUMC, offered an important example for rural community health care in contemporary China. Moreover, it demonstrated and inspired the concepts of the primary health care advocated by World Health Organization 40 years later.
    MeSH term(s) China ; Delivery of Health Care ; History, 20th Century ; Humans ; Rural Health Services/history ; Rural Health Services/organization & administration ; Rural Population ; Universities
    Language Chinese
    Publishing date 2016-07-28
    Publishing country China
    Document type Historical Article ; Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    DOI 10.3760/cma.j.issn.0255-7053.2016.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4688: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Carbon nanotube amendment for treating dichlorodiphenyltrichloroethane and hexachlorocyclohexane remaining in Dong-ting Lake sediment - An implication for in-situ remediation.

    Zhang, Jian / Gong, Ji-Lai / Zeng, Guang-Ming / Yang, Hu-Cheng / Zhang, Peng

    The Science of the total environment

    2017  Volume 579, Page(s) 283–291

    Abstract: ... of Returning Farmland to Lake in China, which caused contamination of sediment in Dong-ting Lake ... concentrations of 0.058, 0.145 and 0.29wt% were used to manage residual DDTs and HCHs in Dong-ting Lake sediment ...

    Abstract Organochlorine pesticides (OCPs) were largely sprayed on the floodplain soils before the project of Returning Farmland to Lake in China, which caused contamination of sediment in Dong-ting Lake with dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) and posed threats to human health and other organisms. In this study, single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) at different concentrations of 0.058, 0.145 and 0.29wt% were used to manage residual DDTs and HCHs in Dong-ting Lake sediment. The efficacy was assessed by DDTs and HCHs deriving from the aqueous equilibrium experiment and uptake in semipermeable membrane devices (SPMDs). Desorption experiment and the quiescent flux experiment were conducted as well. The results showed that DDTs and HCHs were released from sediment. The p, p'-DDT was desorbed less readily than its metabolites and similarly α-HCH was desorbed less easily than other HCH isomers from sediment. Carbon nanotubes had great effects on treating DDTs and HCHs. The effectiveness of carbon nanotube amendment was dependent on type, dose and sediment-sorbent contact time In addition, carbon nanotubes being sprinkled on the surface of sediment as a cap and being injected into sediment as a mixture were considered as two effective ways to prevent DDTs and HCHs being released from sediment. Carbon nanotubes can be potentially useful as sorbents in in-situ remediation.
    Language English
    Publishing date 2017-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2016.11.105
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Potential distribution of Notopterygium incisum Ting ex H. T. Chang and its predicted responses to climate change based on a comprehensive habitat suitability model

    Zefang Zhao / Yanlong Guo / Haiyan Wei / Qiao Ran / Jing Liu / Quanzhong Zhang / Wei Gu

    Ecology and Evolution, Vol 10, Iss 6, Pp 3004-

    2020  Volume 3016

    Abstract: Abstract Notopterygium incisum Ting ex H. T. Chang is a rare and endangered ...

    Abstract Abstract Notopterygium incisum Ting ex H. T. Chang is a rare and endangered traditional Chinese medicinal plant. In this research, we built a comprehensive habitat suitability (CHS) model to analyze the potential suitable habitat distribution of this species in the present and future in China. First, using nine different algorithms, we built an ensemble model to explore the possible impacts of climate change on the habitat distribution of this species. Then, based on this model, we built a CHS model to further identify the distribution characteristics of N. incisum‐suitable habitats in three time periods (current, 2050s, and 2070s) while considering the effects of soil and vegetation conditions. The results indicated that the current suitable habitat for N. incisum covers approximately 83.76 × 103 km2, and these locations were concentrated in the Tibet Autonomous Region, Gansu Province, Qinghai Province, and Sichuan Province. In the future, the areas of suitable habitat for N. incisum would significantly decrease and would be 69.53 × 103 km2 and 60.21 × 103 km2 in the 2050s and 2070s, respectively. However, the area of marginally suitable habitat would remain relatively stable. This study provides a more reliable and comprehensive method for modelling the current and future distributions of N. incisum, and it provides valuable insights for highlighting priority areas for medicinal plant conservation and resource utilization.
    Keywords climate change ; ensemble model ; Notopterygium incisum Ting ex H. T. Chang ; potential distribution ; species distribution models ; Ecology ; QH540-549.5
    Subject code 333
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book: Zhong ji ting li

    Lin, Ling / Zhang, Nian / Zhou, Xiaobing

    ke ben 3 = Intermediate Listening : Textbook 3

    (Jie ti han yu : 阶梯汉语 ; = Step by step chinese / Zhou Xiaobing ; 3)

    2007  

    Author's details Lin Ling, Zhang Nian
    Series title Jie ti han yu : 阶梯汉语
    = Step by step chinese / Zhou Xiaobing ; 3
    Language Chinese
    Size 171 S., ill
    Publisher Hua yu jiao xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787802000278 ; 7802000270
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Book: Zhong ji ting li

    Lin, Ling / Zhang, Ge / Zhou, Xiaobing

    ke ben 2 = Intermediate Listening : Textbook 2

    (Jie ti han yu : 阶梯汉语 ; = Step by step chinese / Zhou Xiaobing ; 2)

    2007  

    Author's details Lin Ling, Zhang Ge
    Series title Jie ti han yu : 阶梯汉语
    = Step by step chinese / Zhou Xiaobing ; 2
    Language Chinese
    Size 178 S., ill
    Publisher Hua yu jiao xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787802000261 ; 7802000262
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book: Zhong ji ting li

    Lin, Ling / Zhang, Nian / Zhou, Xiaobing

    lian xi ce 3 = Intermediate Listening : Workbook 3

    (Jie ti han yu : 阶梯汉语 ; = Step by step chinese / Zhou Xiaobing ; 3)

    2007  

    Author's details Lin Ling, Zhang Nian
    Series title Jie ti han yu : 阶梯汉语
    = Step by step chinese / Zhou Xiaobing ; 3
    Language Chinese
    Size 135 S.
    Publisher Hua yu jiao xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787802000230 ; 7802000238
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book: Zhong ji ting li

    Lin, Ling / Zhang, Ge / Zhou, Xiaobing

    lian xi ce 2 = Intermediate Listening : Workbook 2

    (Jie ti han yu : 阶梯汉语 ; = Step by step chinese / Zhou Xiaobing ; 2)

    2007  

    Author's details Lin Ling, Zhang Ge
    Series title Jie ti han yu : 阶梯汉语
    = Step by step chinese / Zhou Xiaobing ; 2
    Language Chinese
    Size 137 S., ill
    Publisher Hua yu jiao xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787802000223 ; 780200022X
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book: Qiang po zheng yu xiang ting zhi liao

    Zhang, Wen

    (Zhonghua nü zi xue yuan xue shu wen ku)

    2014  

    Author's details Zhang Wen zhu
    Series title Zhonghua nü zi xue yuan xue shu wen ku
    MeSH term(s) Obsessive-Compulsive Disorder/therapy ; Play Therapy/methods
    Language Chinese
    Size 2, 3, 2, 4, 170 pages :, illustrations.
    Edition Di 1 ban.
    Document type Book
    ISBN 9787516146668 ; 7516146668
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top