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  1. Book: Pathophysiological aspects of anaemia and the clinical relevance of its correction

    Hörl, Walter H.

    (European journal of clinical investigation ; 35, Suppl. 3)

    2005  

    Author's details guest ed.: Walter H. Hörl
    Series title European journal of clinical investigation ; 35, Suppl. 3
    Collection
    Language English
    Size 106 S. : graph. Darst.
    Publisher Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014584659
    Database Catalogue ZB MED Medicine, Health

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    Zs A 677 -35,Suppl.3- not available for loan Zeitschriften-Lesesaal

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  2. Book ; Conference proceedings: Emerging insights in anaemia management

    Hörl, Walter H.

    the need for a flexible approach ; proceedings of a Technical Forum [Entitled "Emerging Insights in Anaemia Management: the Need for a Flexible Approach"] held at the 38th ERA-EDTA congress ; 26 June 2001, Vienna, Austria

    (Nephrology, dialysis, transplantation ; 17, Suppl. 6)

    2002  

    Institution European Renal Association
    Event/congress Technical Forum Entitled Emerging Insights in Anaemia Management: the Need for a Flexible Approach (2001, Wien)
    Author's details ed. Walter H. Hörl
    Series title Nephrology, dialysis, transplantation ; 17, Suppl. 6
    Collection
    Language English
    Size 21 S. : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT013410183
    Database Catalogue ZB MED Medicine, Health

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    Zs A 2198 -17,Suppl.6- not available for loan Zeitschriften-Lesesaal

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  3. Book: Replacement of renal function by dialysis

    Drukker, William / Hörl, Walter H.

    2004  

    Author's details Drukker ... Ed. by Walter H. Hörl
    Keywords Renal Dialysis / methods ; Renal Dialysis / adverse effects ; Kidney Failure / physiopathology ; Kidney Failure / therapy ; Kidney, Artificial ; Nierenfunktionsstörung ; Dialyse
    Subject Niere
    Language English
    Size XXI, 1606 S. : Ill., graph. Darst.
    Edition 5. ed., completely rewritten
    Publisher Kluwer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT014077598
    ISBN 1-4020-0083-9 ; 978-1-4020-0083-6
    Database Catalogue ZB MED Medicine, Health

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    2004 A 5005 order for loan Magazin

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  4. Book ; Conference proceedings: Abstracts / Congress of Nephrology 2000

    Hörl, Walter H.

    joint scientific meeting ; September 2 - 5, 2000, Vienna, Austria

    (Kidney & blood pressure research ; 23. 2000,3/5)

    2000  

    Institution Gesellschaft für Nephrologie
    Deutsche Arbeitsgemeinschaft für Klinische Nephrologie
    Event/congress Kongreß für Nephrologie (2000, Wien)
    Author's details Gesellschaft für Nephrologie ; Deutsche Arbeitsgemeinschaft für Klinische Nephrologie ... Eds.: W. H. Hörl
    Series title Kidney & blood pressure research ; 23. 2000,3/5
    Collection
    Keywords Nephrology / congresses ; Kidney Diseases / congresses
    Language English
    Size S. 146 - 353 : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT012815494
    ISBN 3-8055-7153-4 ; 978-3-8055-7153-1
    Database Catalogue ZB MED Medicine, Health

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    Zs A 1458 -23- not available for loan Zeitschriften-Lesesaal

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  5. Book ; Conference proceedings: 9th International Congress on Nutrition and Metabolism in Renal Disease

    Hörl, Walter H.

    Vienna/Austria, ... August 29th - September 1st, 1998

    (Wiener klinische Wochenschrift ; 110, Suppl. 4)

    1998  

    Institution International Society for Renal Nutrition and Metabolism
    Event/congress International Congress on Nutrition and Metabolism in Renal Disease (9, 1998, Wien)
    Author's details International Society of Renal Nutrition & Metabolism. Ed. by Walter H. Hörl
    Series title Wiener klinische Wochenschrift ; 110, Suppl. 4
    Collection
    Language English
    Size 70 S. : graph. Darst.
    Publisher Springer
    Publishing place Wien u.a.
    Publishing country Austria
    Document type Book ; Conference proceedings
    HBZ-ID HT009133910
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 902 -110,Suppl.4- not available for loan Zeitschriften-Lesesaal

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  6. Book: Fresenius Polysulfone - membrane developments to meet clinical demands

    Hörl, Walter H.

    (Clinical nephrology ; 42, Suppl. 1)

    1994  

    Author's details guest ed.: W. H. Hörl
    Series title Clinical nephrology ; 42, Suppl. 1
    Collection
    Keywords Polymers ; Sulfones ; Biocompatible Materials ; Membranes, Artificial ; Hämodialyse ; Maschine ; Membranfilter
    Subject Ultrafilter ; Maschinen ; Blutdialyse ; Blutwäsche
    Language English
    Size S60 S. : Ill., graph. Darst.
    Publisher Dustri-Verl. Feistle
    Publishing place München-Deisenhofen
    Document type Book
    HBZ-ID HT006310679
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 873 -42,Suppl.1- verfügbar in Königswinter Königswinter

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  7. Article ; Online: Anaemia management and mortality risk in chronic kidney disease.

    Hörl, Walter H

    Nature reviews. Nephrology

    2013  Volume 9, Issue 5, Page(s) 291–301

    Abstract: Renal anaemia is a frequent complication in patients with chronic kidney disease (CKD). Severe anaemia (haemoglobin <90 g/l) is associated with increased risks of mortality and cardiac complications, such as left ventricular hypertrophy and ... ...

    Abstract Renal anaemia is a frequent complication in patients with chronic kidney disease (CKD). Severe anaemia (haemoglobin <90 g/l) is associated with increased risks of mortality and cardiac complications, such as left ventricular hypertrophy and cardiovascular disease, and impaired quality of life. Randomized controlled trials have tested the hypothesis that increasing haemoglobin level using erythropoiesis-stimulating agents (ESAs) lowers these risks and improves quality of life. Use of ESAs to normalize haemoglobin levels (to ≥130 g/l) versus the partial correction of anaemia (to haemoglobin levels of 90-110 g/l) has repeatedly been shown to have no cardiac benefit and to be associated with no incremental improvement in outcomes and quality of life (except fatigue), but has been shown to be associated with an increased risk of cardiovascular events and death. Use of more-intense iron dosing has been proposed in order to reduce ESA dosing but liberal intravenous iron therapy is also associated with complications, and its long-term safety has not yet been adequately investigated. For patients with CKD on dialysis, US medication labels recommend administering ESAs at doses sufficient to avoid transfusions, whereas European and Canadian labels recommend targeting haemoglobin levels of 100-120 g/l and 110-120 g/l, respectively. Treatment of anaemia to haemoglobin levels of 90-110 g/l in patients with CKD accomplishes what we want--a reduced need for transfusions and possible reductions in fatigue, while avoiding high doses of ESA or iron in order to achieve a specific haemoglobin goal.
    MeSH term(s) Anemia/drug therapy ; Anemia/mortality ; Blood Transfusion ; Hematinics/therapeutic use ; Humans ; Iron/therapeutic use ; Renal Insufficiency, Chronic/mortality ; Risk Factors
    Chemical Substances Hematinics ; Iron (E1UOL152H7)
    Language English
    Publishing date 2013-02-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/nrneph.2013.21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6334: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 107: Show issues

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  8. Article ; Online: Differentiating factors between erythropoiesis-stimulating agents: an update to selection for anaemia of chronic kidney disease.

    Hörl, Walter H

    Drugs

    2013  Volume 73, Issue 2, Page(s) 117–130

    Abstract: Erythropoiesis-stimulating agents (ESAs) have become a hallmark of anaemia therapy in patients with chronic kidney disease (CKD). Although different ESAs are available for the treatment of renal anaemia, each nephrologist should select a single ESA for ... ...

    Abstract Erythropoiesis-stimulating agents (ESAs) have become a hallmark of anaemia therapy in patients with chronic kidney disease (CKD). Although different ESAs are available for the treatment of renal anaemia, each nephrologist should select a single ESA for an individual patient. Epoetin alfa and epoetin beta have been used 1-3 times weekly but extended-interval dosing up to every 4 weeks is also effective in a substantial majority of CKD patients. However, the epoetin dose necessary to achieve or maintain target haemoglobin (Hb) levels increases substantially as the dosing interval increases. Subcutaneous administration of short-acting ESAs is more effective than the intravenous route of administration. Darbepoetin alfa and the continuous erythropoietin receptor activator (CERA) have been developed as a treatment for anaemia with extended administration intervals (every 2 weeks and every 4 weeks, respectively). Dose requirements for these long-acting ESAs are independent of the route of administration. Patents of short-acting ESAs have expired, which has opened the field for biosimilars. Epoetin biosimilars approved by the European Medicines Agency (EMA) or the US Food and Drug Administration (FDA) have been shown to have a comparable efficacy and safety profile to their originators. An alarming increase in pure red cell aplasia (PRCA) in Thailand with follow-on epoetins manufactured in Asia (but also those manufactured in Latin America) indicates that stringent country-specific approval and pharmacovigilance protocols for ESAs manufactured in non-North American and non-EU European countries are urgently needed. Two PRCA cases occurring with subcutaneous HX575 (one certain, one likely) indicate that chances of inducing a more immunogenic product are unpredictable, even with a biosimilar epoetin approved under the EMA biosimilar approval pathway. Phase III clinical trials with peginesatide, a pegylated synthetic peptide-based ESA without any homology to erythropoietin raised safety concerns in non-dialysis CKD patients but not in dialysis patients.
    MeSH term(s) Anemia/drug therapy ; Anemia/etiology ; Biosimilar Pharmaceuticals ; Darbepoetin alfa ; Erythropoiesis/drug effects ; Erythropoietin/adverse effects ; Erythropoietin/analogs & derivatives ; Erythropoietin/therapeutic use ; Hematinics/adverse effects ; Hematinics/therapeutic use ; Humans ; Injections, Intravenous/methods ; Injections, Subcutaneous/methods ; Peptides/adverse effects ; Peptides/therapeutic use ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/therapeutic use ; Randomized Controlled Trials as Topic ; Red-Cell Aplasia, Pure/chemically induced ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy ; Time Factors
    Chemical Substances Biosimilar Pharmaceuticals ; Hematinics ; Peptides ; continuous erythropoietin receptor activator ; Erythropoietin (11096-26-7) ; Darbepoetin alfa (15UQ94PT4P) ; Polyethylene Glycols (3WJQ0SDW1A) ; peginesatide (JX56W9N61Q)
    Language English
    Publishing date 2013-01-22
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 120316-2
    ISSN 1179-1950 ; 0012-6667
    ISSN (online) 1179-1950
    ISSN 0012-6667
    DOI 10.1007/s40265-012-0002-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 762: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Book ; Conference proceedings: New aspects of human polymorphonuclear leukocytes

    Hörl, Walter H.

    [proceedings of a Workshop on New Aspects of Human Polymorphonuclear Leukocytes, held October 26 - 28, 1989, in Freiburg, Germany]

    (Advances in experimental medicine and biology ; 297)

    1991  

    Event/congress Workshop on New Aspects of Human Polymorphonuclear Leukocytes (1989, FreiburgimBreisgau)
    Author's details ed. by W. H. Hörl
    Series title Advances in experimental medicine and biology ; 297
    Collection
    Keywords Neutrophils / congresses ; Neutrophiler Granulozyt
    Language English
    Size VIII, 228 S. : Ill., graph. Darst.
    Publisher Plenum Pr
    Publishing place New York u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT003905293
    ISBN 0-306-43906-9 ; 978-0-306-43906-3
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 3192 -297- verfügbar in Königswinter Königswinter

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  10. Book: Academic festschrift on the occasion of the sixty fifth birthday of Professor August Heidland

    Heidland, August / Hörl, Walter H.

    (Nephrology, dialysis, transplantation ; 9, Suppl. 3)

    1994  

    Author's details ed.: W. H. Hoerl
    Series title Nephrology, dialysis, transplantation ; 9, Suppl. 3
    Collection
    Keywords Kidney Diseases / essays
    Language English
    Size 50 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT006260173
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 2198 -9,Suppl.3- verfügbar in Königswinter Königswinter

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