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  1. Article ; Online: Prenatal diagnosis and genetic counselling of a maternally inherited chromosome 7q36.3 duplication with normal phenotype in a Chinese family.

    Liu, Fangfang / He, Chun / Quan, Yan

    Taiwanese journal of obstetrics & gynecology

    2024  Volume 63, Issue 2, Page(s) 250–252

    MeSH term(s) Pregnancy ; Female ; Humans ; Genetic Counseling ; Maternal Inheritance ; Prenatal Diagnosis ; Chromosome Duplication ; Phenotype ; Chromosomes ; China
    Language English
    Publishing date 2024-01-09
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2202946-1
    ISSN 1875-6263 ; 1875-6263
    ISSN (online) 1875-6263
    ISSN 1875-6263
    DOI 10.1016/j.tjog.2024.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Degradable bifunctional phototherapy composites based on upconversion nanoparticle-metal phenolic network for multimodal tumor therapy in the near-infrared biowindow.

    Liu, Fangfang / Li, Yong / Wei, Qin / Liu, Jinliang

    Journal of colloid and interface science

    2024  Volume 663, Page(s) 436–448

    Abstract: Phototherapy has garnered increasing attention as it allows for precise treatment of tumor sites with its accurate spatiotemporal control. In this study, we have successfully synthesized degradable bifunctional phototherapy agents (UCNPs@ ... ...

    Abstract Phototherapy has garnered increasing attention as it allows for precise treatment of tumor sites with its accurate spatiotemporal control. In this study, we have successfully synthesized degradable bifunctional phototherapy agents (UCNPs@mSiO
    MeSH term(s) Humans ; Phototherapy ; Photochemotherapy ; Neoplasms/drug therapy ; Combined Modality Therapy ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Metals ; Nanoparticles ; Cell Line, Tumor ; Tumor Microenvironment
    Chemical Substances Doxorubicin (80168379AG) ; Metals
    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.02.173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  3. Article ; Online: Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction.

    Li, Shuang / Zhao, Disong / Yang, Fangfang / Liu, Shufeng

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 5, Page(s) 570–573

    Abstract: A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions was proposed, using DNA strands as the fuel and lambda exonuclease as the fuel-consuming unit. This non-equilibrium system is reversible and ... ...

    Abstract A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions was proposed, using DNA strands as the fuel and lambda exonuclease as the fuel-consuming unit. This non-equilibrium system is reversible and temporally controllable. Furthermore, it can be well integrated into a DNA network to temporally control its cascade reaction or dynamic behaviour.
    MeSH term(s) DNA/genetics ; Recombination, Genetic
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc05061k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Engineering circular bacteriocins: structural and functional effects of α-helix exchanges and disulfide introductions in circularin A.

    Liu, Fangfang / van Heel, Auke J / Kuipers, Oscar P

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1337647

    Abstract: Circular bacteriocins form a distinct group of antimicrobial peptides (AMPs) characterized by their unique head-to-tail ligated circular structure and functional properties. They belong to the ribosomally synthesized and post-translationally modified ... ...

    Abstract Circular bacteriocins form a distinct group of antimicrobial peptides (AMPs) characterized by their unique head-to-tail ligated circular structure and functional properties. They belong to the ribosomally synthesized and post-translationally modified peptide (RiPP) family. The ribosomal origin of these peptides facilitates rapid diversification through mutations in the precursor genes combined with specific modification enzymes. In this study, we primarily explored the bacteriocin engineering potential of circularin A, a circular bacteriocin produced by
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1337647
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  5. Article ; Online: Electrohydrogenation of Nitriles with Amines by Cobalt Catalysis.

    Wang, Tiantian / He, Fangfang / Jiang, Wei / Liu, Jie

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 7, Page(s) e202316140

    Abstract: Catalytic hydrogenation of nitriles represents an efficient and sustainable one-step synthesis of valuable bulk and fine chemicals. We report herein a molecular cobalt electrocatalyst for selective hydrogenative coupling of nitriles with amines using ... ...

    Abstract Catalytic hydrogenation of nitriles represents an efficient and sustainable one-step synthesis of valuable bulk and fine chemicals. We report herein a molecular cobalt electrocatalyst for selective hydrogenative coupling of nitriles with amines using protons as the hydrogen source. The key to success for this reductive reaction is the use of an electrocatalytic approach for efficient cobalt-hydride generation through a sequence of cathodic reduction and protonation. As only electrons (e
    Language English
    Publishing date 2024-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202316140
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  6. Article ; Online: The role of TIA1 and TIAL1 in germinal center B cell function and survival.

    Wang, Yongqiang / Liu, Jisheng / Zhou, Fangfang

    Cellular & molecular immunology

    2023  Volume 20, Issue 9, Page(s) 1090–1092

    MeSH term(s) B-Lymphocytes ; Germinal Center
    Language English
    Publishing date 2023-08-25
    Publishing country China
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-023-01067-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6681: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Exploring the impact of natural resources and energy transition on CO

    Gu, Fangfang / Liu, Xiaohong

    Environmental science and pollution research international

    2023  Volume 30, Issue 36, Page(s) 86110–86121

    Abstract: As reported at the 26th UN Climate Change Conference (COP26), worsening climate situation has led to frequent extreme weather events around the world. The main cause of climate change is carbon emissions from human activities. While realizing rapid ... ...

    Abstract As reported at the 26th UN Climate Change Conference (COP26), worsening climate situation has led to frequent extreme weather events around the world. The main cause of climate change is carbon emissions from human activities. While realizing rapid economic development, China has become the world's largest energy consumer and carbon emitter. To achieve the goal of carbon neutrality by 2060, it should reasonably use natural resources (NR) and promote energy transition (ET). In this study based on panel data on 30 Chinese provinces from 2004 to 2020, second generation panel unit root tests were performed after validating slope heterogeneity and cross-sectional dependency. Mean group (MG) estimation and error correction model were used to empirically test the impact of natural resources and energy transition on CO
    MeSH term(s) Humans ; Carbon Dioxide/analysis ; Cross-Sectional Studies ; China ; Renewable Energy ; Natural Resources ; Economic Development ; Carbon
    Chemical Substances Carbon Dioxide (142M471B3J) ; Carbon (7440-44-0)
    Language English
    Publishing date 2023-07-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28286-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  8. Article ; Online: Chloroplast immunity: A cornerstone of plant defense.

    Liu, Jie / Gong, Pan / Lu, Ruobin / Lozano-Durán, Rosa / Zhou, Xueping / Li, Fangfang

    Molecular plant

    2024  

    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393618-6
    ISSN 1752-9867 ; 1674-2052
    ISSN (online) 1752-9867
    ISSN 1674-2052
    DOI 10.1016/j.molp.2024.03.012
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  9. Article ; Online: 2-Aminopurine-based quencher-free DNA tweezers with fluorescence properties well tuned by surrounding bases.

    Yang, Fangfang / Li, Shuang / Wu, Jialiang / Liu, Shufeng

    Analytical methods : advancing methods and applications

    2024  Volume 16, Issue 4, Page(s) 576–582

    Abstract: Reversible structural changes in DNA nanomachines have great potential in the field of bioanalysis. Here, we demonstrate an assembly strategy for quencher-free and tunable DNA tweezers based on 2-aminopurine (2-AP), avoiding the tedious fluorescence ... ...

    Abstract Reversible structural changes in DNA nanomachines have great potential in the field of bioanalysis. Here, we demonstrate an assembly strategy for quencher-free and tunable DNA tweezers based on 2-aminopurine (2-AP), avoiding the tedious fluorescence labelling step. The conformational state of the tweezers could be controlled by specific oligonucleotides (fuel or anti-fuel). Taking advantage of the local environmental sensitivity of 2-AP, the structural changes of the tweezers were easily tracked, and multiple cyclic switching of the tweezers between the open and closed states was achieved. In addition, the influence of oligonucleotide structure on the fluorescence properties of 2-AP was deeply explored. We figured out that the fluorescence of 2-AP was highly quenched by the base-stacking of natural bases in DNA oligonucleotides. Moreover, by comprehensively regulating the type of bases surrounding the inserted 2-AP site, a sensitive fluorescence response towards dynamic change can be obtained. This principle of quencher-free nanodevices based on 2-AP provides a convenient method for monitoring the structural changes of DNA nanomachines.
    MeSH term(s) 2-Aminopurine/chemistry ; Fluorescence ; DNA/chemistry ; Oligonucleotides/chemistry ; Base Sequence
    Chemical Substances 2-Aminopurine (452-06-2) ; DNA (9007-49-2) ; Oligonucleotides
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d3ay01973j
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  10. Article ; Online: Successful treatment of 1 patient with chlorine-induced ARDS using awake self-prone positioning and nasal high-flow oxygen: A case report.

    Wang, Fugui / Liu, Fangfang / Lu, Houqing

    Medicine

    2024  Volume 103, Issue 3, Page(s) e36995

    Abstract: Rationale: Accidents involving chlorinated compounds in the context of cleaning are not uncommon. However, improving the treatment success rate for acute respiratory distress syndrome (ARDS) patients caused by chlorine gas presents significant ... ...

    Abstract Rationale: Accidents involving chlorinated compounds in the context of cleaning are not uncommon. However, improving the treatment success rate for acute respiratory distress syndrome (ARDS) patients caused by chlorine gas presents significant challenges.
    Patient concerns: A 28-year-old female was admitted to the intensive care unit after accidental inhalation of chlorine gas resulting in ARDS.
    Diagnoses: The patient was diagnosed with ARDS attributed to chlorine gas exposure.
    Interventions: The intervention involved utilizing a combination of awake self-prone positioning (ASPP) and high-flow nasal oxygen therapy for treatment.
    Outcomes: After continuous ASPP and high-flow nasal oxygen therapy, the patient quickly recovered and was transferred out of the intensive care unit on the 6th day without any adverse events.
    Lessons: ASPP combined with high-flow nasal oxygen therapy can improve patients' hypoxemia, prevent the need for intubation, avoid rapid deterioration of the condition, reduce treatment complexity, and lower mortality rate.
    MeSH term(s) Female ; Humans ; Adult ; Oxygen ; Chlorine ; Wakefulness ; Prone Position ; Respiratory Distress Syndrome/chemically induced ; Respiratory Distress Syndrome/therapy ; Patient Positioning/methods
    Chemical Substances Oxygen (S88TT14065) ; Chlorine (4R7X1O2820)
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000036995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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