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  1. Article: [The effect of Ba Duan Jin on the balance of community-dwelling older adults: a cluster randomized control trial].

    Duan, L L / Zhao, Y B / Er, Y L / Ye, P P / Wang, W / Gao, X / Deng, X / Jin, Y / Wang, Y / Ji, C R / Ma, X Y / Gao, C / Zhao, Y H / Zhu, S Q / Su, S Z / Guo, X E / Peng, J J / Yu, Y / Yang, C /
    Su, Y Y / Zhao, M / Guo, L H / Wu, Y P / Luo, Y N / Meng, R L / Xu, H F / Liu, H Z / Ruan, H H / Xie, B / Zhang, H M / Liao, Y H / Chen, Y / Wang, L H

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2024  Volume 45, Issue 2, Page(s) 250–256

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Humans ; Female ; Aged ; Independent Living ; Exercise ; Health Education ; China
    Language Chinese
    Publishing date 2024-02-26
    Publishing country China
    Document type Randomized Controlled Trial ; English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20230506-00283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Three new Spinirta species from China (Araneae, Corinnidae), with the first description of the male of S. leigongshanensis Jin & Zhang, 2020.

    Zhang, L U / Jin, Chi / Zhang, Feng

    Zootaxa

    2023  Volume 5231, Issue 4, Page(s) 445–458

    Abstract: Three new species of the genus Spinirta Jin & Zhang, 2020 are described from China: S ... leigongshanensis Jin & Zhang, 2020 is described for the first time. Finally, we provide an updated distribution map ...

    Abstract Three new species of the genus Spinirta Jin & Zhang, 2020 are described from China: S. shenwushanensis sp. nov., S. lanceola sp. nov. and S. caudata sp. nov.. Additionally, the male of S. leigongshanensis Jin & Zhang, 2020 is described for the first time. Finally, we provide an updated distribution map of the genus.
    MeSH term(s) Male ; Animals ; Spiders ; China ; Animal Distribution
    Language English
    Publishing date 2023-02-01
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5231.4.6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Correction: Jin et al. Effects of Zinc Source and Level on the Intestinal Immunity of Xueshan Chickens under Heat Stress.

    Jin, Jian / Xue, Mengxiao / Tang, Yuchen / Zhang, Liangliang / Hu, Ping / Hu, Yun / Cai, Demin / Luo, Xugang / Sun, Ming-An

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 24

    Abstract: There were some errors in the original publication [ ... ]. ...

    Abstract There were some errors in the original publication [...].
    Language English
    Publishing date 2023-12-05
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13243748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Jin-Zhen oral liquid for pediatric coronavirus disease (COVID-19)

    Qian Dong / Hongmei Qiao / Huiyi Jiang / Lixiao Liu / Yanling Ge / Fang-Jiao Zong / Yanan Li / Bingzi Dong / Sujuan Hu / Dongmei Meng / Rong Jin / Xiangshi Wang / Hailing Chang / Xiaolong Xu / Chenjing Wang / Yu Cao / Han-Ting Zhang / Qingquan Liu

    Frontiers in Pharmacology, Vol

    A randomly controlled, open-label, and non-inferiority trial at multiple clinical centers

    2023  Volume 14

    Abstract: ... as a therapeutic option. Jin-Zhen Oral Liquid is widely used for pediatric acute bronchitis, while the efficacy and ... to moderate COVID-19. Children eligible for enrollment were randomly assigned in a 1:1 ratio to Jin-Zhen Oral ... randomly into the Jin-Zhen Oral Liquid (117 patients) and Jinhua Qinggan Granules (123 patients) groups ...

    Abstract Background: As the coronavirus disease 2019 (COVID-19) pandemic progressed, especially with the emergence of the Omicron variant, the proportion of infected children and adolescents increased significantly. Some treatment such as Chinese herbal medicine has been administered for COVID-19 as a therapeutic option. Jin-Zhen Oral Liquid is widely used for pediatric acute bronchitis, while the efficacy and safety in the treatment of pediatric COVID-19 are unclear.Methods: We conducted a randomized controlled, open-label, multicenter, non-inferiority clinical study involving hospitalized children with mild to moderate COVID-19. Children eligible for enrollment were randomly assigned in a 1:1 ratio to Jin-Zhen Oral Liquid (the treatment group) and Jinhua Qinggan Granules (the positive control group) and received the respective agent for 14 days, followed by a 14-day follow-up after discontinuation of the treatment. The primary efficacy endpoint was the time to first negative viral testing. The secondary endpoints were the time and rate of major symptoms disappearance, duration of hospitalization, and the proportion of symptoms changed from asymptomatic or mild to moderate or severe/critical illness. In addition, the safety end points of any adverse events were observed.Results: A total of 240 child patients were assigned randomly into the Jin-Zhen Oral Liquid (117 patients) and Jinhua Qinggan Granules (123 patients) groups. There was no significant difference of the baselines in terms of the clinical characteristics and initial symptoms between the two groups. After 14-day administration, the time to first negative viral testing in the Jin-Zhen group (median 6.0 days, 95% CI 5.0-6.0) was significantly shorter compared with the positive control Jinhua Qinggan Granules group (median 7.0 days, 95% CI 7.0-8.0). The time and rate of major clinical symptoms disappearance were comparable to the positive control. The symptom disappearance time of pharyngalgia and hospitalization duration were significantly shortened in the ...
    Keywords traditional Chinese medicine ; Jin-Zhen oral liquid ; pediatric COVID-19 ; randomized controlled clinical trial ; multiple clinical centers ; Therapeutics. Pharmacology ; RM1-950
    Subject code 610
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The Role of Zuo Jin Wan in Modulating the Tumor Microenvironment of Colorectal Cancer.

    Wang, Jiajia / Hua, Dongming / Li, Mengyao / Liu, Ningning / Zhang, Yingru / Zhao, Yiyang / Jiang, Shasha / Hu, Xueqing / Wang, Yan / Zhu, Huirong

    Combinatorial chemistry & high throughput screening

    2024  

    Abstract: Introduction: Traditional Chinese medicine (TCM) can modulate the immune function of tumor patients in various ways. Zuojin Wan (ZJW, a 6:1 ratio of Huanglian and Wuzhuyu) can modulate the microenvironment of ulcerative colitis, but its role in ... ...

    Abstract Introduction: Traditional Chinese medicine (TCM) can modulate the immune function of tumor patients in various ways. Zuojin Wan (ZJW, a 6:1 ratio of Huanglian and Wuzhuyu) can modulate the microenvironment of ulcerative colitis, but its role in regulating the CRC microenvironment remains unclear. Exploring the role of ZJW in CRC immunomodulation may improve the antitumor effect of existing immunotherapeutic strategies.
    Material and methods: The active compounds of each herb in ZJW were obtained from the HIT2.0 database with literature evidence. Single-cell RNA sequencing data of CRC were obtained from published studies (PMID: 32451460, 32103181, and 32561858). Pathway enrichment was analyzed using the reactome database, and intergenic correlation analysis was performed using the corrplot R software package. ZJW-regulated gene expression was verified by RT-qPCR.
    Results: Huanglian and Wuzhu contain 19 and 4 compounds, respectively. Huang Lian targets 146 proteins, and Wu Zhu Yu targets 28 proteins based on evidence from the literature. ZJW regulates a range of biological processes associated with immune function, including cytokine signaling and Toll-Like Receptor 4 (TLR4) cascade. ZJW regulates malignant CRC cells, immune cells (including T-cells, B-cells, mast cells, NK/NKT cells, and myeloid cells), and other non-immune cells (including endothelial cells, enteric glial cells, and pericytes). We confirmed that ZJW significantly downregulated the expression of TIMP1 and MTDH.
    Conclusions: ZJW regulates a range of cells in the CRC microenvironment, including malignant CRC, immune cells, and stromal cells. In CRC cell lines, downregulation of TIMP1 and MTDH by ZJW may play an important role in the immunomodulation in CRC.
    Language English
    Publishing date 2024-01-25
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2064785-2
    ISSN 1875-5402 ; 1386-2073
    ISSN (online) 1875-5402
    ISSN 1386-2073
    DOI 10.2174/0113862073281374231228041841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5577: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: An Interview with Jin Zhang.

    Zhang, Jin

    Trends in pharmacological sciences

    2016  Volume 37, Issue 8, Page(s) 619–620

    MeSH term(s) Biosensing Techniques/methods ; Fluorescent Dyes/chemistry ; Humans ; Protein Kinases/metabolism ; Signal Transduction
    Chemical Substances Fluorescent Dyes ; Protein Kinases (EC 2.7.-)
    Language English
    Publishing date 2016
    Publishing country England
    Document type Interview
    ZDB-ID 282846-7
    ISSN 1873-3735 ; 0165-6147
    ISSN (online) 1873-3735
    ISSN 0165-6147
    DOI 10.1016/j.tips.2016.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1513: Show issues Location:
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    Zs.MG 6: Show issues

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  7. Article: Jin-Zhen oral liquid for pediatric coronavirus disease (COVID-19): A randomly controlled, open-label, and non-inferiority trial at multiple clinical centers.

    Dong, Qian / Qiao, Hongmei / Jiang, Huiyi / Liu, Lixiao / Ge, Yanling / Zong, Fang-Jiao / Li, Yanan / Dong, Bingzi / Hu, Sujuan / Meng, Dongmei / Jin, Rong / Wang, Xiangshi / Chang, Hailing / Xu, Xiaolong / Wang, Chenjing / Cao, Yu / Zhang, Han-Ting / Liu, Qingquan

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1094089

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1094089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Light People: Professor Dayong Jin.

    Zhang, Ying

    Light, science & applications

    2021  Volume 10, Issue 1, Page(s) 234

    Abstract: ... Dayong Jin, a Distinguished Professor at the University of Technology Sydney and a Chair Professor ... Dayong Jin to provide his perspectives on his work, end-user driven research, student mentoring and team ... Jin, and appreciate his style and the story behind his success. ...

    Abstract Editorial: He pioneered a new family of nanoscopic probes that can up-convert infrared photons into intense visible light, and won the Australian Museum Eureka Prize for Interdisciplinary Scientific Research in 2015. He created new kinds of microscopes that allow us to watch molecules at work inside living cells, and won the Australian Prime Minister's Prize for Science Malcolm McIntosh Prize for Physical Scientist of the Year 2017. The Australian newspaper identified him among 100 "rock stars of Australia's new economy" as the Knowledge Nation 100. This year, at his age of 42, he won the Australian Laureate Fellowship and was elected to the fellowship of Australian Academy of Technology and Engineering. This is Dayong Jin, a Distinguished Professor at the University of Technology Sydney and a Chair Professor at Southern University of Science and Technology, as well as the editorial manager in Sydney office and the perspective column editor of Light: Science & Applications (LSA). Light People is a featured column of high-end interviews with outstanding scientists. On this issue, it is our great honor to invite Professor Dayong Jin to provide his perspectives on his work, end-user driven research, student mentoring and team building philosophy. In the following, let's take a closer look at the research life of Professor Dayong Jin, and appreciate his style and the story behind his success.
    Language English
    Publishing date 2021-11-27
    Publishing country England
    Document type News
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-021-00673-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Protective effect of compatible herbs in Jin-Gu-Lian formula against

    Lian, Dongyin / Chen, Tengfei / Yan, Lihua / Hou, Hongping / Gao, Shuangrong / Hu, Qin / Zhang, Guangping / Li, Han / Song, Ling / Gao, Yunhang / Pu, Yunxi / Chen, Ying / Peng, Bo

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1133982

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1133982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Network pharmacology-based analysis of Jin-Si-Wei on the treatment of Alzheimer's disease.

    Zhi, Jiayi / Yin, Li / Zhang, Zhoudong / Lv, Yaozhong / Wu, Fan / Yang, Yang / Zhang, Enming / Li, Huanqiu / Lu, Ning / Zhou, Mengze / Hu, Qinghua

    Journal of ethnopharmacology

    2023  Volume 319, Issue Pt 3, Page(s) 117291

    Abstract: Ethnopharmacological relevance: Jin-Si-Wei (JSW), a traditional Chinese medicine (TCM) formula ...

    Abstract Ethnopharmacological relevance: Jin-Si-Wei (JSW), a traditional Chinese medicine (TCM) formula, have cognitive enhancing effect and delay the memory decline in an animal model of AD， which has been reported. However, the therapeutic mechanism of JSW in the treatment of AD remains unclear.
    Aim of the study: This study aimed to verify the pharmacodynamics of JSW in the treatment of AD, and to explore its potential mechanism based on network pharmacology, molecular docking and experimental validation both in vitro and in vivo.
    Materials and methods: In this study, the underlying mechanism of JSW against AD was investigated by the integration of network pharmacology. Then, the core pathways and biological process of JSW were verified by experiment, including behavioral test and pathological and biochemical assays with 6-month-old APP
    Results: A Drug-Ingredient-Target network was established, which included 363 ingredients and 116 targets related to the JSW treatment of AD. The main metabolic pathway of JSW treatment for AD is neuroactive ligand-receptor interaction pathway, and biological processes are mainly involved in Aβ metabolic process. In vivo experiments, compared with APP/PS1 mice, the cognitive and memory ability of mice was significantly improved after JSW administration. In brain tissue of APP/PS1 mice, JSW could increase the contents of low-density lipoprotein receptor-related protein 1 (LRP-1), enkephalinase (NEP) and Acetyl choline (ACh), and decrease the contents of Aβ
    Conclusions: JSW improves AD in APP/PS1 mice, and this therapeutic effect may be achieved in part by altering the neuroactive ligand-receptor interaction pathway.
    MeSH term(s) Humans ; Animals ; Mice ; Alzheimer Disease/drug therapy ; Ligands ; Molecular Docking Simulation ; Network Pharmacology ; Neuroblastoma ; Amyloid beta-Protein Precursor/genetics ; Amyloid Precursor Protein Secretases
    Chemical Substances Ligands ; Amyloid beta-Protein Precursor ; Amyloid Precursor Protein Secretases (EC 3.4.-)
    Language English
    Publishing date 2023-11-02
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.117291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1494: Show issues Location:
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