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  1. Book: Selbsthilfe bei Long Covid

    Barizien, Nicolas / Uzan, Laurent / Samitier, Marie-Pierre

    das 8-Wochen-Programm gegen Müdigkeit, Geschmacksverlust, Kurzatmigkeit und Brain Fog in Folge einer Corona-Infektion

    2022  

    Title translation Covid long: Commment s'en sortir
    Author's details Nicolas Barizien, Laurent Uzan, Marie-Pierre Samitier
    Keywords Coronavirus ; Langzeitfolgen ; Atemnot ; Herz-Kreislaufprobleme ; Antriebslosigkeit ; Immunsystem stärken ; Depression ; Rehabilitation ; Konzentrationsschwäche ; Achtsamkeit ; natürlich heilen ; Neuinfektion ; Pandemie ; Therapie ; Long-COVID ; Selbsttherapie
    Subject Selbstbehandlung ; Eigentherapie
    Language German
    Size 224 Seiten, Illustrationen, 24 cm x 17 cm
    Edition 1. Auflage
    Publisher riva
    Publishing place München
    Publishing country Germany
    Document type Book
    HBZ-ID HT021431244
    ISBN 978-3-7423-2117-6 ; 3-7423-2117-X ; 9783745318937 ; 9783745318944 ; 3745318935 ; 3745318943
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Clinical characterization of dysautonomia in long COVID-19 patients.

    Barizien, Nicolas / Le Guen, Morgan / Russel, Stéphanie / Touche, Pauline / Huang, Florent / Vallée, Alexandre

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 14042

    Abstract: Increasing numbers of COVID-19 patients, continue to experience symptoms months after recovering from mild cases of COVID-19. Amongst these symptoms, several are related to neurological manifestations, including fatigue, anosmia, hypogeusia, headaches ... ...

    Abstract Increasing numbers of COVID-19 patients, continue to experience symptoms months after recovering from mild cases of COVID-19. Amongst these symptoms, several are related to neurological manifestations, including fatigue, anosmia, hypogeusia, headaches and hypoxia. However, the involvement of the autonomic nervous system, expressed by a dysautonomia, which can aggregate all these neurological symptoms has not been prominently reported. Here, we hypothesize that dysautonomia, could occur in secondary COVID-19 infection, also referred to as "long COVID" infection. 39 participants were included from December 2020 to January 2021 for assessment by the Department of physical medicine to enhance their physical capabilities: 12 participants with COVID-19 diagnosis and fatigue, 15 participants with COVID-19 diagnosis without fatigue and 12 control participants without COVID-19 diagnosis and without fatigue. Heart rate variability (HRV) during a change in position is commonly measured to diagnose autonomic dysregulation. In this cohort, to reflect HRV, parasympathetic/sympathetic balance was estimated using the NOL index, a multiparameter artificial intelligence-driven index calculated from extracted physiological signals by the PMD-200 pain monitoring system. Repeated-measures mixed-models testing group effect were performed to analyze NOL index changes over time between groups. A significant NOL index dissociation over time between long COVID-19 participants with fatigue and control participants was observed (p = 0.046). A trend towards significant NOL index dissociation over time was observed between long COVID-19 participants without fatigue and control participants (p = 0.109). No difference over time was observed between the two groups of long COVID-19 participants (p = 0.904). Long COVID-19 participants with fatigue may exhibit a dysautonomia characterized by dysregulation of the HRV, that is reflected by the NOL index measurements, compared to control participants. Dysautonomia may explain the persistent symptoms observed in long COVID-19 patients, such as fatigue and hypoxia. Trial registration: The study was approved by the Foch IRB: IRB00012437 (Approval Number: 20-12-02) on December 16, 2020.
    MeSH term(s) Adult ; COVID-19/complications ; Fatigue/complications ; Female ; Heart Rate ; Humans ; Male ; Middle Aged ; Primary Dysautonomias/complications ; Primary Dysautonomias/physiopathology
    Language English
    Publishing date 2021-07-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-93546-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: 'Post-COVID-19 chronic symptoms' - Author's reply.

    Davido, Benjamin / Seang, Sophie / Barizien, Nicolas / Tubiana, Roland / de Truchis, Pierre

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2020  Volume 27, Issue 3, Page(s) 495–496

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2020.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical characterization of dysautonomia in long COVID-19 patients

    Nicolas Barizien / Morgan Le Guen / Stéphanie Russel / Pauline Touche / Florent Huang / Alexandre Vallée

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 7

    Abstract: Abstract Increasing numbers of COVID-19 patients, continue to experience symptoms months after recovering from mild cases of COVID-19. Amongst these symptoms, several are related to neurological manifestations, including fatigue, anosmia, hypogeusia, ... ...

    Abstract Abstract Increasing numbers of COVID-19 patients, continue to experience symptoms months after recovering from mild cases of COVID-19. Amongst these symptoms, several are related to neurological manifestations, including fatigue, anosmia, hypogeusia, headaches and hypoxia. However, the involvement of the autonomic nervous system, expressed by a dysautonomia, which can aggregate all these neurological symptoms has not been prominently reported. Here, we hypothesize that dysautonomia, could occur in secondary COVID-19 infection, also referred to as “long COVID” infection. 39 participants were included from December 2020 to January 2021 for assessment by the Department of physical medicine to enhance their physical capabilities: 12 participants with COVID-19 diagnosis and fatigue, 15 participants with COVID-19 diagnosis without fatigue and 12 control participants without COVID-19 diagnosis and without fatigue. Heart rate variability (HRV) during a change in position is commonly measured to diagnose autonomic dysregulation. In this cohort, to reflect HRV, parasympathetic/sympathetic balance was estimated using the NOL index, a multiparameter artificial intelligence-driven index calculated from extracted physiological signals by the PMD-200 pain monitoring system. Repeated-measures mixed-models testing group effect were performed to analyze NOL index changes over time between groups. A significant NOL index dissociation over time between long COVID-19 participants with fatigue and control participants was observed (p = 0.046). A trend towards significant NOL index dissociation over time was observed between long COVID-19 participants without fatigue and control participants (p = 0.109). No difference over time was observed between the two groups of long COVID-19 participants (p = 0.904). Long COVID-19 participants with fatigue may exhibit a dysautonomia characterized by dysregulation of the HRV, that is reflected by the NOL index measurements, compared to control participants. Dysautonomia may explain the persistent ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 150
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Prehabilitation Program in Elderly Patients: A Prospective Cohort Study of Patients Followed Up Postoperatively for Up to 6 Months.

    Malot, Claire / Durand-Bouteau, Astrid / Barizien, Nicolas / Bizard, Antoine / Kennel, Titouan / Fischler, Marc / Minnella, Enrico / Le Guen, Morgan

    Journal of clinical medicine

    2021  Volume 10, Issue 19

    Abstract: The preoperative period may be an opportune period to optimize patients' physical condition with a multimodal preoperative program. The impact of a "prehabilitation" program on elderly patients is discussed. This mono-center observational cohort study ... ...

    Abstract The preoperative period may be an opportune period to optimize patients' physical condition with a multimodal preoperative program. The impact of a "prehabilitation" program on elderly patients is discussed. This mono-center observational cohort study included consecutively 139 patients planned for major abdominal and thoracic surgery, with 44 in the control group (age < 65) and 95 in the elderly group (age > 65). All patients followed a "prehabilitation" program including exercise training, nutritional optimization, psychological support, and behavioral change. Seventeen patients in the control group and 45 in the elderly group completed the study at six months. The 6-minute walk test (6 MWT) increased in both groups from the initial evaluation to the last (median value of 80 m (interquartile range 51) for those under 65 years; 59 m (34) for the elderly group;
    Language English
    Publishing date 2021-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10194500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: 'Post-COVID-19 chronic symptoms' – Author's reply

    Davido, Benjamin / Seang, Sophie / Barizien, Nicolas / Tubiana, Roland / de Truchis, Pierre

    Clinical Microbiology and Infection ; ISSN 1198-743X

    2020  

    Keywords Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.cmi.2020.09.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Prehabilitation Program in Elderly Patients

    Claire Malot / Astrid Durand-Bouteau / Nicolas Barizien / Antoine Bizard / Titouan Kennel / Marc Fischler / Enrico Minnella / Morgan Le Guen

    Journal of Clinical Medicine, Vol 10, Iss 4500, p

    A Prospective Cohort Study of Patients Followed Up Postoperatively for Up to 6 Months

    2021  Volume 4500

    Abstract: The preoperative period may be an opportune period to optimize patients’ physical condition with a multimodal preoperative program. The impact of a “prehabilitation” program on elderly patients is discussed. This mono-center observational cohort study ... ...

    Abstract The preoperative period may be an opportune period to optimize patients’ physical condition with a multimodal preoperative program. The impact of a “prehabilitation” program on elderly patients is discussed. This mono-center observational cohort study included consecutively 139 patients planned for major abdominal and thoracic surgery, with 44 in the control group (age < 65) and 95 in the elderly group (age > 65). All patients followed a “prehabilitation” program including exercise training, nutritional optimization, psychological support, and behavioral change. Seventeen patients in the control group and 45 in the elderly group completed the study at six months. The 6-minute walk test (6 MWT) increased in both groups from the initial evaluation to the last (median value of 80 m (interquartile range 51) for those under 65 years; 59 m (34) for the elderly group; p = 0.114). The 6 MWT was also similar after one month of prehabilitation for both populations. The rate of postoperative complications was similar in the two groups. Prehabilitation showed equivalence in patients over 65 years of age compared to younger patients in terms of increase in functional capabilities and of postoperative evolution. This multimodal program represents a bundle of care that can benefit a frailer population.
    Keywords prehabilitation ; elderly ; surgery ; walk test ; Medicine ; R
    Subject code 796
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: High incidence of hyperventilation syndrome after COVID-19.

    Taverne, Jérémie / Salvator, Hélène / Leboulch, Cécile / Barizien, Nicolas / Ballester, Marie / Imhaus, Etienne / Chabi-Charvillat, Marie-Laure / Boulin, Anne / Goyard, Céline / Chabrol, Alexandre / Catherinot, Emilie / Givel, Claire / Couderc, Louis-Jean / Tcherakian, Colas

    Journal of thoracic disease

    2021  Volume 13, Issue 6, Page(s) 3918–3922

    Language English
    Publishing date 2021-06-29
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-20-2753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The role of athletes' pain-related anxiety in pain-related attentional processes.

    Bardel, Marie-Héloïse / Woodman, Tim / Perreaut-Pierre, Edith / Barizien, Nicolas

    Anxiety, stress, and coping

    2013  Volume 26, Issue 5, Page(s) 573–583

    Abstract: Numerous researchers have highlighted the social determinants of athletes' attitude toward pain, yet little is known about the role of cognitive processes and emotions that are related to pain in sport endeavors. There is evidence, in a dot probe ... ...

    Abstract Numerous researchers have highlighted the social determinants of athletes' attitude toward pain, yet little is known about the role of cognitive processes and emotions that are related to pain in sport endeavors. There is evidence, in a dot probe paradigm, that individuals with chronic pain selectively orient their attention toward pain-related stimuli, but no studies have differentiated between the two attentional processes of hypervigilance that are evident in athletes: facilitated detection of threat and difficulty in disengaging attention from threatening stimuli. In the present study using a dot probe paradigm, we examined whether professional rugby players (N=58) with high pain-related anxiety (HPA) would show an attentional bias for pain-related threat, and whether this hypervigilance would reflect difficulty disengaging from threat or facilitated detection of threat. Rugby players with HPA oriented their attention toward pain-related threat with a concomitant difficulty disengaging from threat. Difficulty disengaging from painful stimuli may increase anxiety, and thus be maladaptive in sport. This is the first study to identify pain-related anxiety as a vulnerability marker in athletes' attentional biases.
    MeSH term(s) Adolescent ; Adult ; Analysis of Variance ; Anxiety/psychology ; Athletes/psychology ; Athletes/statistics & numerical data ; Attention/physiology ; Football ; France ; Humans ; Pain/psychology ; Photic Stimulation/methods ; Reaction Time/physiology ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2013-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1115932-7
    ISSN 1477-2205 ; 1061-5806
    ISSN (online) 1477-2205
    ISSN 1061-5806
    DOI 10.1080/10615806.2012.757306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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