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  1. Article: Uncommon and Rare

    Fabrizio, Federico Pio / Attili, Ilaria / de Marinis, Filippo

    Cancers

    2024  Volume 16, Issue 7

    Abstract: Uncommon (ucEGFRmuts) and rare epidermal growth factor receptor ( ...

    Abstract Uncommon (ucEGFRmuts) and rare epidermal growth factor receptor (
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16071331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Conference proceedings: 12th National AIOM Conference - Thoracic Cancers

    De Marinis, Filippo

    29 - 31 March, 2006: Rome, Italy

    (Annals of oncology ; 17, Suppl. 2 ; National AIOM conference ; 12)

    2006  

    Institution Associazione Italiana di Oncologia Medica
    Event/congress National Conference Thoracic Cancers (2006, Rom)
    Author's details guest ed.: Filippo de Marinis
    Series title Annals of oncology ; 17, Suppl. 2
    National AIOM conference ; 12
    Collection
    Language English
    Size ii100 S. : Ill.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT014737339
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Looking for the high way in EGFR-positive non-small cell lung cancer through the evaluation of survival endpoints.

    Passaro, Antonio / de Marinis, Filippo

    Translational lung cancer research

    2020  Volume 8, Issue Suppl 4, Page(s) S334–S338

    Language English
    Publishing date 2020-01-30
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2754335-3
    ISSN 2226-4477 ; 2218-6751
    ISSN (online) 2226-4477
    ISSN 2218-6751
    DOI 10.21037/tlcr.2019.06.04
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Neoadjuvant Chemotherapy Plus Immunotherapy in Early-Stage Resectable Non-Small-Cell Lung Cancer.

    Passaro, Antonio / Attili, Ilaria / de Marinis, Filippo

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2022  Volume 40, Issue 25, Page(s) 2871–2877

    Abstract: The Oncology Grand Rounds series is designed to place original reports published in ... ...

    Abstract The Oncology Grand Rounds series is designed to place original reports published in the
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Humans ; Immunotherapy/methods ; Lung Neoplasms/drug therapy ; Neoadjuvant Therapy ; Small Cell Lung Carcinoma
    Language English
    Publishing date 2022-06-17
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.00873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Rescue Surgery after Immunotherapy/Tyrosine Kinase Inhibitors for Initially Unresectable Lung Cancer.

    Galetta, Domenico / De Marinis, Filippo / Spaggiari, Lorenzo

    Cancers

    2022  Volume 14, Issue 11

    Abstract: Background: We report the outcomes for unresectable patients with locally advanced or oligometastatic non-small cell lung cancer (NSCLC) treated with tyrosine kinase inhibitor (TKI) or immunotherapy who achieved a clinical downstaging so as to re-enter ... ...

    Abstract Background: We report the outcomes for unresectable patients with locally advanced or oligometastatic non-small cell lung cancer (NSCLC) treated with tyrosine kinase inhibitor (TKI) or immunotherapy who achieved a clinical downstaging so as to re-enter resectability.
    Methods: We retrospectively reviewed the clinical, surgical, and pathological data of 42 patients with histologically proven, inoperable NSCLC who received rescue surgery after a good response to TKI or immunotherapy between March 2014 and December 2021.
    Results: Of 42 patients, 39 underwent pulmonary resection with therapeutic intent (three explorative thoracotomies). There were 26 males, with a median age of 64 years (range, 41-78 years). Twenty-three patients received TKIs and 19 immunotherapies. Anatomic resection was performed in 97.4% of resected patients (38/39) including 30 lobectomies, one right upper sleeve lobectomy, five pneumonectomies, one tracheal sleeve pneumonectomy, and one bilobectomy; a patient underwent wedge resection. Of 10 procedures attempted via a robotic approach, two required conversion to thoracotomy. No intraoperative morbidity/mortality occurred. The median operative time was 190 (range, 80-426) minutes; estimated blood loss was 200 mL (range, 35-780 mL). Morbidity occurred in 13/39 (33.3%). The median length of hospital stay was 6.5 days (range, 4-23 days). Pathologic downstaging was 74.4% (29/39). With a median follow-up of 28.7 months, the 5-year disease-free interval was 46.5%, and the 5-year overall survival was 66.0%; 32/39 patients (82.1%) are alive, 10 with the disease.
    Conclusions: Lung resection for suspected residual disease after immunotherapy or TKIs is feasible, with encouraging pathological downstaging. Surgical operation may be technically challenging due to the presence of fibrosis, but significant morbidity appears to be rare. Outcomes are encouraging, with reasonable survival during the short-interval follow-up.
    Language English
    Publishing date 2022-05-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14112661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: CheckMate 9LA: broadening treatment options for patients with non-small-cell lung cancer.

    Passaro, Antonio / Attili, Ilaria / de Marinis, Filippo

    The Lancet. Oncology

    2021  Volume 22, Issue 2, Page(s) 157–159

    MeSH term(s) Antineoplastic Agents, Immunological/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Humans ; Ipilimumab/therapeutic use ; Lung Neoplasms/drug therapy ; Nivolumab/therapeutic use
    Chemical Substances Antineoplastic Agents, Immunological ; Ipilimumab ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2021-01-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(20)30701-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Dacomitinib in EGFR-positive non-small cell lung cancer: an attractive but broken option.

    Passaro, Antonio / de Marinis, Filippo

    Translational lung cancer research

    2018  Volume 7, Issue Suppl 2, Page(s) S100–S102

    Language English
    Publishing date 2018-05-17
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2754335-3
    ISSN 2226-4477 ; 2218-6751
    ISSN (online) 2226-4477
    ISSN 2218-6751
    DOI 10.21037/tlcr.2018.02.09
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Reply.

    Passaro, Antonio / Spitaleri, Gianluca / de Marinis, Filippo

    Clinical lung cancer

    2020  Volume 21, Issue 5, Page(s) e415–e416

    MeSH term(s) ErbB Receptors ; Humans ; Lung Neoplasms ; Mutation
    Chemical Substances EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1)
    Language English
    Publishing date 2020-02-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2145146-1
    ISSN 1938-0690 ; 1525-7304
    ISSN (online) 1938-0690
    ISSN 1525-7304
    DOI 10.1016/j.cllc.2020.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Uncommon

    Attili, Ilaria / Passaro, Antonio / Pisapia, Pasquale / Malapelle, Umberto / de Marinis, Filippo

    Current oncology (Toronto, Ont.)

    2022  Volume 29, Issue 1, Page(s) 255–266

    Abstract: Compound epidermal growth factor receptor ( ...

    Abstract Compound epidermal growth factor receptor (
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; ErbB Receptors ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use
    Chemical Substances Protein Kinase Inhibitors ; EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1)
    Language English
    Publishing date 2022-01-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol29010024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Incorporating atezolizumab in the adjuvant setting of non-small cell lung cancer: key discussion points from an expert multidisciplinary panel by Italian Association of Thoracic Oncology.

    de Marinis, Filippo / Attili, Ilaria / Gridelli, Cesare / Cecere, Fabiana / Curcio, Carlo / Facciolo, Francesco / Spaggiari, Lorenzo

    Frontiers in oncology

    2022  Volume 12, Page(s) 971042

    Language English
    Publishing date 2022-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.971042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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