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  1. Article ; Online: Using two self-developed InDel panels to explore forensic traits and ancestral components in the Hui group.

    Yuan, Xi / Wang, Xi / Lan, Qiong / Li, Shuanglin / Lin, Yifeng / Zhao, Ming / Xu, Hui / Lei, Fanzhang / Shen, Chunmei / Zhu, Bofeng

    Genomics

    2023  Volume 116, Issue 1, Page(s) 110756

    Abstract: ... of these two panels were tested in the Chinese Hui group. By calculating forensic parameters and simulating ... paternity testing, and could assist in kinship identification in the Hui group. For full siblings, the true ...

    Abstract To address the challenges faced by forensic examiners in degraded DNA analysis, we have developed two different panels for various forensic applications, encompassing an AIM-InDel panel for ancestry inference and a Multi-InDel panel for individual identification, respectively. Herein, the efficiencies of these two panels were tested in the Chinese Hui group. By calculating forensic parameters and simulating family relationships, we verified that the Multi-InDel panel could be an effective tool for individual identification, paternity testing, and could assist in kinship identification in the Hui group. For full siblings, the true positive rate of kinship discrimination was 96.553%, when the threshold of log
    MeSH term(s) Humans ; China ; Ethnicity/genetics ; Gene Frequency ; Genetics, Population ; INDEL Mutation ; Minority Groups ; Phenotype ; East Asian People/genetics
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 356334-0
    ISSN 1089-8646 ; 0888-7543
    ISSN (online) 1089-8646
    ISSN 0888-7543
    DOI 10.1016/j.ygeno.2023.110756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Performance evaluation of an in-house panel containing 59 autosomal InDels for forensic identification in Chinese Hui and Mongolian groups.

    Fang, Yating / Liu, Yanfang / Xu, Hui / Zhu, Bofeng

    Genomics

    2022  Volume 115, Issue 1, Page(s) 110552

    Abstract: ... of these loci were investigated in Chinese Hui (n = 249) and Mongolian (n = 222) ethnic groups using direct ... that the values of the combined power of discrimination were 0.9999999999999999999999999999006 (Hui) and 0 ... 999999999999999999999999999738 (Mongolian), respectively. Moreover, the combined power of exclusion values were 0.99999817 (Hui ...

    Abstract In recent years, a novel multiplex system containing two mini-short tandem repeats, 59 autosomal InDels, two Y-chromosomal InDels, and the Amelogenin gene with all amplicons less than 200 bp has been constructed and validated by ourselves for forensic degration sample, and its forensic application efficiency has been studied in Chinese some populations. Herein, the population genetic polymorphisms of these loci were investigated in Chinese Hui (n = 249) and Mongolian (n = 222) ethnic groups using direct multiplex amplification and capillary electrophoresis platform. The forensic identification efficiencies of this self-developed system were further evaluated in these two groups. And the results showed that the values of the combined power of discrimination were 0.9999999999999999999999999999006 (Hui) and 0.999999999999999999999999999738 (Mongolian), respectively. Moreover, the combined power of exclusion values were 0.99999817 (Hui) and 0.99999779 (Mongolian). The 59 autosomal InDels used in this study exhibited high forensic identification efficiencies in 10 East Asian populations, which was also expected to be a new powerful tool for identifying degraded biological materials in East Asian populations.
    MeSH term(s) Humans ; Asian People/genetics ; China ; East Asian People ; Gene Frequency ; Genetics, Population ; INDEL Mutation ; Microsatellite Repeats ; Polymorphism, Genetic ; Mongolia
    Language English
    Publishing date 2022-12-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 356334-0
    ISSN 1089-8646 ; 0888-7543
    ISSN (online) 1089-8646
    ISSN 0888-7543
    DOI 10.1016/j.ygeno.2022.110552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The massive assimilation of indigenous East Asian populations in the origin of Muslim Hui people inferred from paternal Y chromosome.

    Wang, Chuan-Chao / Lu, Yan / Kang, Longli / Ding, Huiqian / Yan, Shi / Guo, Jianxin / Zhang, Qun / Wen, Shao-Qing / Wang, Ling-Xiang / Zhang, Manfei / Tong, Xinzhu / Huang, Xiufeng / Nie, Shengjie / Deng, Qiongying / Zhu, Bofeng / Jin, Li / Li, Hui

    American journal of physical anthropology

    2019  Volume 169, Issue 2, Page(s) 341–347

    Abstract: Objectives: The Hui people are the adherents of Muslim faith and distributing throughout China ... There are two contrasting hypotheses about the origin and diversification of the Hui people, namely ... methods: We collected 621 unrelated male individuals from 23 Hui populations all over China ...

    Abstract Objectives: The Hui people are the adherents of Muslim faith and distributing throughout China. There are two contrasting hypotheses about the origin and diversification of the Hui people, namely, the demic diffusion involving the mass movement of people or simple cultural diffusion.
    Materials and methods: We collected 621 unrelated male individuals from 23 Hui populations all over China. We comprehensively genotyped more than 100 informative Y-chromosomal single nucleotide polymorphisms and 17 Y-chromosomal short tandem repeats (STRs) on those samples.
    Results: Co-analyzed with published worldwide populations, our results suggest the origin of Hui people has involved massive assimilation of indigenous East Asians with about 70% in total of the paternal ancestry could be traced back to East Asia and the left 30% to various regions in West Eurasia.
    Discussion: The genetic structure of the extant Hui populations was primarily shaped by the indigenous East Asian populations as they contribute the majority part of the paternal lineages of Hui people. The West Eurasian admixture was probably a sex-biased male-driven process since we have not found such a high proportion of West Eurasian gene flow on autosomal STRs and maternal mtDNA.
    MeSH term(s) Anthropology, Physical ; Asian Continental Ancestry Group/genetics ; China ; Chromosomes, Human, Y/genetics ; Ethnic Groups/genetics ; Gene Flow/genetics ; Genetics, Population ; Humans ; Islam ; Male ; Polymorphism, Single Nucleotide/genetics
    Language English
    Publishing date 2019-03-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.23823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Occurrence of Enterocytozoon bieneusi in Chinese Tan sheep in the Ningxia Hui Autonomous Region, China.

    Peng, Jun-Jie / Zou, Yang / Li, Zhi-Xin / Liang, Qin-Li / Song, Hai-Yang / Li, Tao-Shan / Ma, Yuan-Yuan / Zhu, Xing-Quan / Zhou, Dong-Hui

    Parasitology research

    2019  Volume 118, Issue 9, Page(s) 2729–2734

    Abstract: ... species in the Ningxia Hui Autonomous Region, China. The objectives of the present study were to examine ... of Tan sheep from six farms in the Ningxia Hui Autonomous Region were examined by nested PCR ...

    Abstract Enterocytozoon bieneusi is a zoonotic parasite which is considered to be an opportunistic pathogen of humans and animals. A number of studies have reported E. bieneusi infection in various animals. However, no information is available on the occurrence of E. bieneusi in Tan sheep, a unique indigenous sheep species in the Ningxia Hui Autonomous Region, China. The objectives of the present study were to examine the prevalence and identify the genotypes of E. bieneusi in Tan sheep in China. A total of 1014 fecal specimens of Tan sheep from six farms in the Ningxia Hui Autonomous Region were examined by nested PCR amplification of the internal transcribed spacer (ITS) of nuclear ribosomal DNA. The total prevalence of E. bieneusi was 12.2% (124/1014), ranging from 0.5 to 22.2% on six farms. Sequence analysis identified 10 genotypes of E. bieneusi, including three known genotypes, BEB6, COS-I, and CHG13, and seven novel genotypes designated as NX1 to NX7, which all belonged to group 2 by phylogenetic analysis. This is the first report describing the prevalence of E. bieneusi in Tan sheep, and the new genotypes identified in the current study expand the genotype distribution of E. bieneusi. These findings provide baseline data and have implications for the epidemiology and control of E. bieneusi infection in Tan sheep.
    MeSH term(s) Animals ; China/epidemiology ; Enterocytozoon/classification ; Enterocytozoon/genetics ; Enterocytozoon/isolation & purification ; Genotype ; Microsporidiosis/epidemiology ; Microsporidiosis/parasitology ; Microsporidiosis/veterinary ; Phylogeny ; Prevalence ; Sheep ; Sheep Diseases/epidemiology ; Sheep Diseases/parasitology
    Language English
    Publishing date 2019-07-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-019-06398-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Male-Dominated Migration and Massive Assimilation of Indigenous East Asians in the Formation of Muslim Hui People in Southwest China.

    Wang, Qiyan / Zhao, Jing / Ren, Zheng / Sun, Jin / He, Guanglin / Guo, Jianxin / Zhang, Hongling / Ji, Jingyan / Liu, Yubo / Yang, Meiqing / Yang, Xiaomin / Chen, Jinwen / Zhu, Kongyang / Wang, Rui / Li, Yingxiang / Chen, Gang / Huang, Jiang / Wang, Chuan-Chao

    Frontiers in genetics

    2021  Volume 11, Page(s) 618614

    Abstract: The origin and diversification of Muslim Hui people in China via demic or simple cultural diffusion ... single nucleotide polymorphisms (SNPs) from 45 Hui and 14 Han Chinese individuals collected from Guizhou province in southwest ...

    Abstract The origin and diversification of Muslim Hui people in China via demic or simple cultural diffusion is a long-going debate. We here generated genome-wide data at nearly 700,000 single nucleotide polymorphisms (SNPs) from 45 Hui and 14 Han Chinese individuals collected from Guizhou province in southwest China. We applied principal component analysis (PCA), ADMIXTURE,
    Language English
    Publishing date 2021-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2020.618614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing.

    Chen, Chong / Li, Yuchun / Tao, Ruiyang / Jin, Xiaoye / Guo, Yuxin / Cui, Wei / Chen, Anqi / Yang, Yue / Zhang, Xingru / Zhang, Jingyi / Li, Chengtao / Zhu, Bofeng

    Genes

    2020  Volume 11, Issue 11

    Abstract: ... provides a pivotal way for us to investigate the formation histories of populations. The Hui minority ... the world as reference data, to comprehensively dissect the matrilineal landscape of Hui group. Our results ... demonstrated that Hui group exhibited closer genetic relationships with Chinese Han populations from different ...

    Abstract Mitochondrial DNA (mtDNA), coupled with maternal inheritance and relatively high mutation rates, provides a pivotal way for us to investigate the formation histories of populations. The Hui minority with Islamic faith is one of the most widely distributed ethnic groups in China. However, the exploration of Hui's genetic architecture from the complete mitochondrial genome perspective has not been detected yet. Therefore, in this study, we employed the complete mitochondrial genomes of 98 healthy and unrelated individuals from Northwest China, as well as 99 previously published populations containing 7274 individuals from all over the world as reference data, to comprehensively dissect the matrilineal landscape of Hui group. Our results demonstrated that Hui group exhibited closer genetic relationships with Chinese Han populations from different regions, which was largely attributable to the widespread of haplogroups D4, D5, M7, B4, and F1 in these populations. The demographic expansion of Hui group might occur during the Late Pleistocene. Finally, we also found that Hui group might have gene exchanges with Uygur, Tibetan, and Tajik groups in different degrees and retained minor genetic imprint of European-specific lineages, therefore, hinting the existence of multi-ethnic integration events in shaping the genetic landscape of Chinese Hui group.
    MeSH term(s) Asian People/genetics ; China/ethnology ; DNA, Mitochondrial/genetics ; Ethnicity/genetics ; Genetic Variation ; Genetics, Population ; Genome, Mitochondrial ; Haplotypes ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Population Dynamics ; Principal Component Analysis
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2020-11-14
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes11111352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers.

    Chen, Chong / Jin, Xiaoye / Zhang, Xingru / Zhang, Wenqing / Guo, Yuxin / Tao, Ruiyang / Chen, Anqi / Xu, Qiannan / Li, Min / Yang, Yue / Zhu, Bofeng

    Frontiers in genetics

    2021  Volume 12, Page(s) 705753

    Abstract: The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed ... A-STRs), into 90 unrelated male individuals from the Chinese Northwest Hui group to comprehensively ... based distinct alleles were identified from 58 short tandem repeats (STRs) in 90 unrelated Northwest Hui ...

    Abstract The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China. In the present study, we employed the length and sequence polymorphisms-based typing system of 231 molecular markers, i.e., amelogenin, 22 phenotypic-informative single nucleotide polymorphisms (PISNPs), 94 identity-informative single nucleotide polymorphisms (IISNPs), 24 Y-chromosomal short tandem repeats (Y-STRs), 56 ancestry-informative single nucleotide polymorphisms (AISNPs), 7 X-chromosomal short tandem repeats (X-STRs), and 27 autosomal short tandem repeats (A-STRs), into 90 unrelated male individuals from the Chinese Northwest Hui group to comprehensively explore its forensic characteristics and genetic background. Total of 451 length-based and 652 sequence-based distinct alleles were identified from 58 short tandem repeats (STRs) in 90 unrelated Northwest Hui individuals, denoting that the sequence-based genetic markers could pronouncedly provide more genetic information than length-based markers. The forensic characteristics and efficiencies of STRs and IISNPs were estimated, both of which externalized high polymorphisms in the Northwest Hui group and could be further utilized in forensic investigations. No significant departure from the Hardy-Weinberg equilibrium (HWE) expectation was observed after the Bonferroni correction. Additionally, four group sets of reference population data were exploited to dissect the genetic background of the Northwest Hui group separately from different perspectives, which contained 26 populations for 93 IISNPs, 58 populations for 17 Y-STRs, 26 populations for 55 AISNPs (raw data), and 109 populations for 55 AISNPs (allele frequencies). As a result, the analyses based on the Y-STRs indicated that the Northwest Hui group primarily exhibited intimate genetic relationships with reference Hui groups from Chinese different regions except for the Sichuan Hui group and secondarily displayed close genetic relationships with populations from Central and West Asia, as well as several Chinese groups. However, the AISNP analyses demonstrated that the Northwest Hui group shared more intimate relationships with current East Asian populations apart from reference Hui group, harboring the large proportion of ancestral component contributed by East Asia.
    Language English
    Publishing date 2021-10-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2021.705753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Occurrence of Enterocytozoon bieneusi in Chinese Tan sheep in the Ningxia Hui Autonomous Region, China

    Peng, Jun-Jie / Zou, Yang / Li, Zhi-Xin / Liang, Qin-Li / Song, Hai-Yang / Li, Tao-Shan / Ma, Yuan-Yuan / Zhu, Xing-Quan / Zhou, Dong-Hui

    Parasitology research. 2019 Sept., v. 118, no. 9

    2019  

    Abstract: ... species in the Ningxia Hui Autonomous Region, China. The objectives of the present study were to examine ... of Tan sheep from six farms in the Ningxia Hui Autonomous Region were examined by nested PCR ...

    Abstract Enterocytozoon bieneusi is a zoonotic parasite which is considered to be an opportunistic pathogen of humans and animals. A number of studies have reported E. bieneusi infection in various animals. However, no information is available on the occurrence of E. bieneusi in Tan sheep, a unique indigenous sheep species in the Ningxia Hui Autonomous Region, China. The objectives of the present study were to examine the prevalence and identify the genotypes of E. bieneusi in Tan sheep in China. A total of 1014 fecal specimens of Tan sheep from six farms in the Ningxia Hui Autonomous Region were examined by nested PCR amplification of the internal transcribed spacer (ITS) of nuclear ribosomal DNA. The total prevalence of E. bieneusi was 12.2% (124/1014), ranging from 0.5 to 22.2% on six farms. Sequence analysis identified 10 genotypes of E. bieneusi, including three known genotypes, BEB6, COS-I, and CHG13, and seven novel genotypes designated as NX1 to NX7, which all belonged to group 2 by phylogenetic analysis. This is the first report describing the prevalence of E. bieneusi in Tan sheep, and the new genotypes identified in the current study expand the genotype distribution of E. bieneusi. These findings provide baseline data and have implications for the epidemiology and control of E. bieneusi infection in Tan sheep.
    Keywords Enterocytozoon bieneusi ; epidemiology ; farms ; feces ; genotype ; indigenous species ; internal transcribed spacers ; parasites ; phylogeny ; polymerase chain reaction ; ribosomal DNA ; secondary infection ; sequence analysis ; sheep ; sheep diseases ; China
    Language English
    Dates of publication 2019-09
    Size p. 2729-2734.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 284966-5
    ISSN 1432-1955 ; 0932-0113 ; 0044-3255
    ISSN (online) 1432-1955
    ISSN 0932-0113 ; 0044-3255
    DOI 10.1007/s00436-019-06398-4
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui.

    Yao, Hong-Bing / Wang, Chuan-Chao / Tao, Xiaolan / Shang, Lei / Wen, Shao-Qing / Zhu, Bofeng / Kang, Longli / Jin, Li / Li, Hui

    Scientific reports

    2016  Volume 6, Page(s) 38656

    Abstract: ... Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely ... 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations ... and Hui people during their Islamization. The dataset generated in present study are also valuable ...

    Abstract There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry. Our analysis found no evidence of substantial gene flow from Middle East or Europe into Dongxiang and Hui people during their Islamization. The dataset generated in present study are also valuable for forensic identification and paternity tests in China.
    Language English
    Publishing date 2016-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep38656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Jian kang yu she hui

    Zhu, Pingyi

    Hua ren wei sheng xin shi

    2013  

    Title variant Hua ren wei sheng xin shi
    Author's details Zhu Pingyi bian
    MeSH term(s) Public Health/history ; Attitude to Health ; Communicable Disease Control/history ; History, 19th Century ; History, 20th Century
    Keywords China
    Language Chinese
    Size ii, 353 p :, ill. ;, 23 cm.
    Edition Chu ban.
    Publisher Lian jing chu ban shi ye gu fen you xian gong si
    Publishing place Taibei Shi
    Document type Book
    ISBN 9789570841220 ; 9570841222
    Database Catalogue of the US National Library of Medicine (NLM)

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