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  1. Article ; Online: Analysis of Characteristics of Endometrial Carcinoma in Peri- and Postmenopausal Women with Abnormal Uterine Bleeding.

    Yanli, Ye / Mei, Wang Tian / Cong, Li

    BioMed research international

    2024  Volume 2024, Page(s) 6509171

    Abstract: Objective: To analyze the menstrual characteristics of endometrial carcinoma and investigate whether abnormal uterine bleeding in the perimenopausal period differs from postmenopausal bleeding.: Methods: We conducted a retrospective analysis of 928 ... ...

    Abstract Objective: To analyze the menstrual characteristics of endometrial carcinoma and investigate whether abnormal uterine bleeding in the perimenopausal period differs from postmenopausal bleeding.
    Methods: We conducted a retrospective analysis of 928 cases of endometrial carcinoma in patients admitted from January 2016 to December 2022. We gathered fundamental clinical data and analyzed distinct clinical risk factors between the perimenopausal and postmenopausal groups. Furthermore, we computed the statistical variances in menarche, regular menstrual cycles, and the duration of abnormal uterine bleeding.
    Results: Perimenopausal patients with endometrial carcinoma exhibit similar factors to postmenopausal patients, especially if they have a history of menstrual cycles lasting more than 30 years, hypertension, abnormal uterine bleeding for over 1 year, and a high risk of endometrial carcinoma. Early intervention for abnormal uterine bleeding during the perimenopausal stage can prevent up to 80% of women from developing endometrial carcinoma.
    Conclusion: Perimenopause women experiencing abnormal uterine bleeding should be mindful of the risk of endometrial carcinoma, as this awareness can substantially decrease the occurrence of the disease.
    MeSH term(s) Humans ; Female ; Postmenopause ; Retrospective Studies ; Endometrial Neoplasms/complications ; Endometrial Neoplasms/epidemiology ; Uterine Hemorrhage ; Early Intervention, Educational
    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2024/6509171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: All-Inorganic Perovskite Solar Cells: Defect Regulation and Emerging Applications in Extreme Environments.

    Shen, Cong / Ye, Tengling / Yang, Peixia / Chen, Guanying

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2401498

    Abstract: All-inorganic perovskite solar cells (PSCs), such as ... ...

    Abstract All-inorganic perovskite solar cells (PSCs), such as CsPbX
    Language English
    Publishing date 2024-03-11
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202401498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Bimolecular Homolytic Substitution-Enabled Platform for Multicomponent Cross-Coupling of Unactivated Alkenes.

    Cong, Fei / Sun, Guo-Quan / Ye, Si-Han / Hu, Rui / Rao, Weidong / Koh, Ming Joo

    Journal of the American Chemical Society

    2024  Volume 146, Issue 15, Page(s) 10274–10280

    Abstract: The construction of C( ...

    Abstract The construction of C(
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c02284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  4. Article: Cognitive emotion regulation for improved mental health: A chain mediation study of Chinese high school students.

    Xue, Meijuan / Cong, Beile / Ye, Yiduo

    Frontiers in psychology

    2023  Volume 13, Page(s) 1041969

    Abstract: High school is a critical time for individual development, during which significant physical and mental changes related to puberty occur. Therefore, high school students' mental health requires more attention from schools, families, and society. Our ... ...

    Abstract High school is a critical time for individual development, during which significant physical and mental changes related to puberty occur. Therefore, high school students' mental health requires more attention from schools, families, and society. Our study explored high school students' present status and family functioning characteristics, psychological capital, cognitive-emotion regulation, and life satisfaction by surveying 917 students in China. Data were analysed using independent sample
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.1041969
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  5. Article ; Online: Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca

    Li, Zhangqiang / Cong, Ye / Wu, Tong / Wang, Tongtong / Lou, Xinyao / Yang, Xinyu / Yan, Nieng

    Cell research

    2024  

    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Letter
    ZDB-ID 1319303-x
    ISSN 1748-7838 ; 1001-0602
    ISSN (online) 1748-7838
    ISSN 1001-0602
    DOI 10.1038/s41422-024-00940-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5283: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Abalone adhesion: The role of various adhesion forces and their proportion to total adhesion force.

    Xi, Peng / Ye, Shaobo / Cong, Qian

    PloS one

    2023  Volume 18, Issue 6, Page(s) e0286567

    Abstract: Adhesion is the basic ability of many kinds of animals in nature, which ensures the survival and reproduction of animal populations. The aquatic abalone has a strong adhesion capacity. In this study, we observed the microscopic morphology of abalone ... ...

    Abstract Adhesion is the basic ability of many kinds of animals in nature, which ensures the survival and reproduction of animal populations. The aquatic abalone has a strong adhesion capacity. In this study, we observed the microscopic morphology of abalone abdominal foot surface, and found that the surface was covered with a large number of fibers. Then five types of force measuring plates were designed and processed for the adhesion test of abalone abdominal foot. According to the test results, the composition of abalone abdominal foot adhesion force was analyzed and the proportion of various adhesion force to the total adhesion force of abalone abdominal foot was calculated. Among them, the vacuum adhesion force accounts for more than half of the total adhesion force of abalone abdominal foot, and its proportion is more than 60%. Van der Waals force also plays an important role, and its proportion is more than 20%. The proportion of capillary force is very small, which is only about 1%. Its main role is to form a liquid film to prevent the gas from flowing into the sucker. The vacuum adhesion of abalone abdominal foot can be further divided into the whole adhesion of abdominal foot, the local adhesion of abdominal foot and the frictional equivalent vacuum adhesion. And the whole adhesion of abdominal foot is basically equivalent to the local adhesion of abdominal foot. This study quantifies the proportion of various adhesion forces to the total adhesion force of the abdominal foot, which provides a reference for the further study of other adhesive creatures and the design of bionic underwater adhesion devices.
    MeSH term(s) Animals ; Surface Properties ; Mechanical Phenomena ; Physical Phenomena ; Gastropoda ; Seafood
    Language English
    Publishing date 2023-06-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0286567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Role of protein degradation systems in colorectal cancer.

    Cui, Zihan / Cong, Mingqi / Yin, Shengjie / Li, Yuqi / Ye, Yuguang / Liu, Xi / Tang, Jing

    Cell death discovery

    2024  Volume 10, Issue 1, Page(s) 141

    Abstract: Protein degradation is essential for maintaining protein homeostasis. The ubiquitin‒proteasome system (UPS) and autophagy-lysosome system are the two primary pathways responsible for protein degradation and directly related to cell survival. In malignant ...

    Abstract Protein degradation is essential for maintaining protein homeostasis. The ubiquitin‒proteasome system (UPS) and autophagy-lysosome system are the two primary pathways responsible for protein degradation and directly related to cell survival. In malignant tumors, the UPS plays a critical role in managing the excessive protein load caused by cancer cells hyperproliferation. In this review, we provide a comprehensive overview of the dual roles played by the UPS and autolysosome system in colorectal cancer (CRC), elucidating their impact on the initiation and progression of this disease while also highlighting their compensatory relationship. Simultaneously targeting both protein degradation pathways offers new promise for enhancing treatment efficacy against CRC. Additionally, apoptosis is closely linked to ubiquitination and autophagy, and caspases degrade proteins. A thorough comprehension of the interplay between various protein degradation pathways is highly important for clarifying the mechanism underlying the onset and progression of CRC.
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2058-7716
    ISSN 2058-7716
    DOI 10.1038/s41420-023-01781-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: MOCAT: multi-omics integration with auxiliary classifiers enhanced autoencoder.

    Yao, Xiaohui / Jiang, Xiaohan / Luo, Haoran / Liang, Hong / Ye, Xiufen / Wei, Yanhui / Cong, Shan

    BioData mining

    2024  Volume 17, Issue 1, Page(s) 9

    Abstract: Background: Integrating multi-omics data is emerging as a critical approach in enhancing our understanding of complex diseases. Innovative computational methods capable of managing high-dimensional and heterogeneous datasets are required to unlock the ... ...

    Abstract Background: Integrating multi-omics data is emerging as a critical approach in enhancing our understanding of complex diseases. Innovative computational methods capable of managing high-dimensional and heterogeneous datasets are required to unlock the full potential of such rich and diverse data.
    Methods: We propose a Multi-Omics integration framework with auxiliary Classifiers-enhanced AuToencoders (MOCAT) to utilize intra- and inter-omics information comprehensively. Additionally, attention mechanisms with confidence learning are incorporated for enhanced feature representation and trustworthy prediction.
    Results: Extensive experiments were conducted on four benchmark datasets to evaluate the effectiveness of our proposed model, including BRCA, ROSMAP, LGG, and KIPAN. Our model significantly improved most evaluation measurements and consistently surpassed the state-of-the-art methods. Ablation studies showed that the auxiliary classifiers significantly boosted classification accuracy in the ROSMAP and LGG datasets. Moreover, the attention mechanisms and confidence evaluation block contributed to improvements in the predictive accuracy and generalizability of our model.
    Conclusions: The proposed framework exhibits superior performance in disease classification and biomarker discovery, establishing itself as a robust and versatile tool for analyzing multi-layer biological data. This study highlights the significance of elaborated designed deep learning methodologies in dissecting complex disease phenotypes and improving the accuracy of disease predictions.
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2438773-3
    ISSN 1756-0381
    ISSN 1756-0381
    DOI 10.1186/s13040-024-00360-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: GAPDH: unveiling its impact as a key hypoxia-related player in head and neck squamous cell carcinoma tumor progression, prognosis, and therapeutic potential.

    Peng, Cong / Ye, Huiping / Yi, Zhuguang

    American journal of cancer research

    2023  Volume 13, Issue 12, Page(s) 5846–5867

    Abstract: Head and neck squamous cell carcinoma (HNSCC), characterized by hypoxia patterns, ranks as the sixth most prevalent malignant tumor worldwide. Glyceraldehyde-3-phosphate dehydrogenase ( ...

    Abstract Head and neck squamous cell carcinoma (HNSCC), characterized by hypoxia patterns, ranks as the sixth most prevalent malignant tumor worldwide. Glyceraldehyde-3-phosphate dehydrogenase (
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2589522-9
    ISSN 2156-6976
    ISSN 2156-6976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: iSalivaomicDB: A comprehensive saliva omics database for insects.

    Zhang, Bo / Chen, Longfei / Xiao, Shan / Dang, Cong / Wang, Fang / Fang, Qi / Ye, Xinhai / Stanley, David W / Ye, Gongyin

    Insect science

    2024  

    Language English
    Publishing date 2024-03-07
    Publishing country Australia
    Document type Letter
    ZDB-ID 2179775-4
    ISSN 1744-7917 ; 1672-9609
    ISSN (online) 1744-7917
    ISSN 1672-9609
    DOI 10.1111/1744-7917.13349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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