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Article ; Online: Serendipity, opportunity and impact.

Mendelson, Marc

Southern African journal of infectious diseases

2022 Volume 37, Issue 2, Page(s) 401

Language	English
Publishing date	2022-02-14
Publishing country	South Africa
Document type	Journal Article
ZDB-ID	3046282-4
ISSN	2313-1810 ; 2312-0053
ISSN (online)	2313-1810
ISSN	2312-0053
DOI	10.4102/sajid.v37i2.401
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Article ; Online: BSAC Vanguard Series: Inequality and antibiotic resistance.

Mendelson, Marc

The Journal of antimicrobial chemotherapy

2021 Volume 77, Issue 2, Page(s) 277–278

Abstract: COVID-19 has highlighted the worldwide inequities in access to the tools needed to tackle the pandemic. The same is the case for antibiotic resistance (ABR), which is projected to cause far greater devastation. The truth is that unless we tackle the ... ...

Abstract	COVID-19 has highlighted the worldwide inequities in access to the tools needed to tackle the pandemic. The same is the case for antibiotic resistance (ABR), which is projected to cause far greater devastation. The truth is that unless we tackle the burden of infectious diseases in low- and middle-income countries (LMICs), we will not impact ABR worldwide. Despite valiant efforts we have largely failed to address antibiotic conservation. We have directed millions of dollars into developing new antibiotics and surveillance systems and mostly ignored interventions such as infection prevention. Insufficient resources are dedicated to interventions such as sanitation and clean water, vaccination and changes in agricultural practice to reduce reliance on antimicrobials. Large-scale public health interventions are required. Funding mechanisms must be found to support LMICs in making these changes. Action is required at the highest levels.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; COVID-19 ; Developing Countries ; Drug Resistance, Microbial ; Humans ; SARS-CoV-2
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-12-13
Publishing country	England
Document type	Journal Article
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkab426
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Zs.A 1197: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Speakers from low- and middle-income countries should have a greater voice at ESCMID conferences.

Mendelson, Marc

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

2021 Volume 27, Issue 8, Page(s) 1182

MeSH term(s)	Developing Countries ; Humans ; Societies, Medical
Language	English
Publishing date	2021-02-27
Publishing country	England
Document type	Letter
ZDB-ID	1328418-6
ISSN	1469-0691 ; 1470-9465 ; 1198-743X
ISSN (online)	1469-0691
ISSN	1470-9465 ; 1198-743X
DOI	10.1016/j.cmi.2021.02.022
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Zs.MO 284: Show issues

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Article ; Online: Could enhanced influenza and pneumococcal vaccination programs help limit the potential damage from SARS-CoV-2 to fragile health systems of southern hemisphere countries this winter?

Mendelson, Marc

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2020 Volume 94, Page(s) 32–33

Keywords	covid19
Language	English
Publishing date	2020-03-16
Publishing country	Canada
Document type	Editorial
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2020.03.030
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Article ; Online: Diagnostic imaging: Doing the right thing.

Mendelson, Richard M

Journal of medical imaging and radiation oncology

2020 Volume 64, Issue 3, Page(s) 353–360

Abstract: Inappropriate diagnostic imaging (DI) is a burgeoning issue and embraces its overuse and its misapplication. The obverse problem is one of underuse - that is when patients who should undergo imaging fail to do so. This article attempts to define these ... ...

Abstract	Inappropriate diagnostic imaging (DI) is a burgeoning issue and embraces its overuse and its misapplication. The obverse problem is one of underuse - that is when patients who should undergo imaging fail to do so. This article attempts to define these problems, examines the causes and effects and suggests some potential solutions.
MeSH term(s)	Diagnostic Imaging/standards ; Health Services Misuse ; Humans ; Unnecessary Procedures
Language	English
Publishing date	2020-02-12
Publishing country	Australia
Document type	Journal Article ; Review
ZDB-ID	2389687-5
ISSN	1754-9485 ; 1440-1673 ; 1754-9477 ; 0004-8461
ISSN (online)	1754-9485 ; 1440-1673
ISSN	1754-9477 ; 0004-8461
DOI	10.1111/1754-9485.13004
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Article ; Online: Use and reporting of inverse-probability-of-treatment weighting for multicategory treatments in medical research: a systematic review.

Bettega, François / Mendelson, Monique / Leyrat, Clémence / Bailly, Sébastien

Journal of clinical epidemiology

2024 Volume 170, Page(s) 111338

Abstract: Objectives: Causal inference methods for observational data represent an alternative to randomised controlled trials when they are not feasible or when real-world evidence is sought. Inverse-probability-of-treatment weighting (IPTW) is one of the most ... ...

Abstract	Objectives: Causal inference methods for observational data represent an alternative to randomised controlled trials when they are not feasible or when real-world evidence is sought. Inverse-probability-of-treatment weighting (IPTW) is one of the most popular approaches to account for confounding in observational studies. In medical research, IPTW is mainly applied to estimate the causal effect of a binary treatment, even when the treatment has in fact multiple categories, despite the availability of IPTW estimators for multiple treatment categories. This raises questions about the appropriateness of the use of IPTW in this context. Therefore, we conducted a systematic review of medical publications reporting the use of IPTW in the presence of a multi-category treatment. Our objectives were to investigate the frequency of use and the implementation of these methods in practice, and to assess the quality of their reporting. Study design and setting: Using Pubmed, Embase and Web of Science, we screened 5660 articles and retained 106 articles in the final analysis that were from 17 different medical areas. This systematic review is registered on PROSPERO (CRD42022352669). Results: The number of treatment groups varied between 3 and 9, with a large majority of articles (90 [84.9%]) including 3 or 4 groups. The most commonly used method for estimating the weights was multinomial regression (51 [48.1%]) and generalized boosted models (48 [45.3%]). The covariates of the weight model were reported in 91 articles (85.9 %). Twenty-six articles (24.5 %) did not discuss the balance of covariates after weighting, and only 16 articles (15.1 %) referred to the assumptions needed to obtain correct inferences. Conclusion: The results of this systematic review illustrate that medical publications scarcely use IPTW methods for more than two treatment categories. Among the publications that did, the quality of reporting was suboptimal, in particular in regard to the assumptions and model building. IPTW for multi-category treatments could be applied more broadly in medical research, and the application of the proposed guidelines in this context will help researchers to report their results and to ensure reproducibility of their research.
Language	English
Publishing date	2024-03-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2024.111338
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Article: Antibodies to 5 M urea soluble chromosomal proteins from HeLa cells.

Dunn, B / Mendelson, E / Soares, N / Bustin, M

Biochimica et biophysica acta

1985 Volume 838, Issue 1, Page(s) 151–160

Abstract: The tissue specificity of a chromosomal protein fraction, extractable from chromatin with 5 M urea ... Electrophoresis in polyacrylamide gels indicates that each cell type has a different content of 5 M urea soluble proteins which are ... chromosomal proteins. Antibodies against 5 M urea soluble proteins extracted from HeLa cells were produced ...

Abstract	The tissue specificity of a chromosomal protein fraction, extractable from chromatin with 5 M urea at low ionic strength, has been examined in HeLa, A549 and HT 29 cells. Electrophoresis in polyacrylamide gels indicates that each cell type has a different content of 5 M urea soluble proteins which are distinguishable from the histones, from the tight DNA-binding proteins and from the high-mobility-group chromosomal proteins. Antibodies against 5 M urea soluble proteins extracted from HeLa cells were produced in mice. Although each of the mice tested prior to immunization contained a detectable amount of antibodies against both the 5 M urea soluble proteins and tight DNA-binding proteins, immunization elevated the level of the antibodies in the serum over 100-fold. The antibodies do not distinguish between the 5 M urea extracts obtained from different sources because most of the antibodies are directed against antigens shared by the cells studied. Immunofluorescence studies reveal that components which cross-react with 5 M urea soluble chromosomal proteins are also present in the cytoplasm. We conclude the following. (1) 5 M urea extracts from chromatin a group of proteins which differs among cells. (2) Mice contain detectable amounts of autoantibodies against these chromosomal proteins. (3) Immunization with the 5 M urea extractable fraction elicits antibodies against a restricted number of antigenic components which are shared among the cells studied. (4) 5 M urea extractable proteins are found both in the nucleus and cytoplasm; part of these may be cytoskeletal elements. Because the antisera do not react with histones, high-mobility-group proteins and tight DNA-binding proteins, they may be used for various functional studies on the 5 M urea extractable chromosomal protein fraction.
MeSH term(s)	Animals ; Antibodies/analysis ; Antibodies/immunology ; Antibody Specificity ; Antigens/immunology ; Cell Line ; Chromatin/analysis ; Chromosomal Proteins, Non-Histone/immunology ; Chromosomal Proteins, Non-Histone/isolation & purification ; Colonic Neoplasms/analysis ; Female ; HeLa Cells/analysis ; Humans ; Immunization ; Lung Neoplasms/analysis ; Mice ; Mice, Inbred BALB C/immunology ; Molecular Weight ; Solubility ; Urea
Chemical Substances	Antibodies ; Antigens ; Chromatin ; Chromosomal Proteins, Non-Histone ; Urea (8W8T17847W)
Language	English
Publishing date	1985-01-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	60-7
ISSN	1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
ISSN (online)	1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650
ISSN	0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
DOI	10.1016/0304-4165(85)90261-2
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Article: Sex differences in the effects of 1-(m-trifluoromethylphenyl) piperazine and 1-(m-chlorophenyl) piperazine on copulatory behavior in the rat.

Mendelson, S D / Gorzalka, B B

Neuropharmacology

1990 Volume 29, Issue 8, Page(s) 783–786

Abstract: Peripheral administrations of TFMPP (0.2- 1 mg/kg) or MCPP (1 mg/kg) facilitated lordosis behavior in female rats treated with estradiol benzoate, and had no effects in females primed with estradiol benzoate and progesterone. In contrast, TFMPP (1 mg/kg) ...

Abstract	Peripheral administrations of TFMPP (0.2- 1 mg/kg) or MCPP (1 mg/kg) facilitated lordosis behavior in female rats treated with estradiol benzoate, and had no effects in females primed with estradiol benzoate and progesterone. In contrast, TFMPP (1 mg/kg) and MCPP (1 mg/kg) inhibited copulatory behavior in male rats. It is concluded that there are sex differences in the effects of TFMPP and MCPP on copulatory behavior in the rat. Moreover, it is suggested that the effects of these drugs on copulatory behavior may be mediated by activation of 5-HT1B and/or 5-HT1C receptors, or by blockade of activity at 5-HT3 receptors.
MeSH term(s)	Animals ; Anticonvulsants/pharmacology ; Copulation/drug effects ; Estradiol/analogs & derivatives ; Estradiol/pharmacology ; Female ; Male ; Ovariectomy ; Piperazines/pharmacology ; Progesterone/pharmacology ; Rats ; Rats, Inbred Strains ; Receptors, Serotonin/drug effects ; Serotonin/physiology ; Sex Factors ; Sexual Behavior, Animal/drug effects
Chemical Substances	Anticonvulsants ; Piperazines ; Receptors, Serotonin ; 1-(3-trifluoromethylphenyl)piperazine (25R3ONU51C) ; Serotonin (333DO1RDJY) ; Progesterone (4G7DS2Q64Y) ; Estradiol (4TI98Z838E) ; estradiol-17 beta-benzoate (983-30-2) ; 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (98Y1I8ZD4M)
Language	English
Publishing date	1990-08
Publishing country	England
Document type	Journal Article
ZDB-ID	218272-5
ISSN	1873-7064 ; 0028-3908
ISSN (online)	1873-7064
ISSN	0028-3908
DOI	10.1016/0028-3908(90)90133-c
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Article ; Online: New-Onset Tinnitus After Dorsal Root Ganglion Stimulator Implantation: A Case Report.

Pressler, Mark P / Brenner, Brian / Kohan, Lynn R / Mendelson, Andrew M

A&A practice

2024 Volume 18, Issue 3, Page(s) e01747

Abstract: Dorsal column (dcSCS) and dorsal root ganglion stimulation (DRG-S) complications are similar, typically related to placement and device failure. We present the first case of tinnitus after DRG-S implantation. The patient presented with complex regional ... ...

Abstract	Dorsal column (dcSCS) and dorsal root ganglion stimulation (DRG-S) complications are similar, typically related to placement and device failure. We present the first case of tinnitus after DRG-S implantation. The patient presented with complex regional pain syndrome (CRPS) type 2. After previous failed treatments, she had a lumbosacral DRG-S trial, which provided relief; however, she briefly noted ringing in her ears. After permanent implantation, she reported persistent, intolerable left-sided tinnitus. Tinnitus can be modulated by secondary somatosensory inputs to the cochlear nucleus from the dcSCS. Therefore, lumbosacral DRG-S stimulating distal sensory neurons leading to tinnitus is a feasible complication.
MeSH term(s)	Female ; Humans ; Tinnitus/etiology ; Tinnitus/therapy ; Ganglia, Spinal ; Spinal Nerve Roots
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	2575-3126
ISSN (online)	2575-3126
DOI	10.1213/XAA.0000000000001747
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Book: ACR BI-RADS®-Atlas der Mammadiagnostik

D'Orsi, Carl J. / Sickles, Edward A. / Mendelson, Ellen B. / Walthers, Eduard M.

Richtlinien zu Befundung, Managementempfehlungen und Monitoring

2016

Institution	American College of Radiology
Author's details	American College of Radiology (Hrsg) ; herausgegeben von Dr. med. Eduard M. Walthers, Marburg/Lahn ; Autoren und Herausgeber der 5. englischen Auflage: Carl J. D'Orsi, Edward A. Sickles, Ellen B. Mendelson [und 7 andere]
Keywords	Befunderstellung ; Befundungssystem ; MR-Mammographie ; Mammographie ; Ultraschall ; Mamma ; Krankheit ; Bildgebendes Verfahren ; Befund ; Standardisierung ; Qualitätssicherung
Subject	Beschaffenheitssicherung ; Unternehmen ; Befunderhebung ; Medizinischer Befund ; Klinischer Befund ; Bildgebendes Diagnoseverfahren ; Diagnostik ; Bilddiagnostik ; Bildgebende Methode ; Medical Imaging ; Medizinische Bildgebung ; Bildgebende Diagnostik ; Bildgebende Verfahren ; Imaging ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Brust ; Busen ; Weibliche Brust
Subject code	618.19075720218
Language	German
Size	XVI, 529 Seiten, 788 Illustrationen, 29 cm
Edition	Deutsche Übersetzung der 5. englischen Auflage, 2013
Publisher	Springer
Publishing place	Berlin
Publishing country	Germany
Document type	Book
HBZ-ID	HT019027903
ISBN	978-3-662-48817-1 ; 9783662488188 ; 3-662-48817-5 ; 3662488183
Database	Catalogue ZB MED Medicine, Health

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