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  1. Article ; Online: COVID-19 in Immunocompromised Hosts: What We Know So Far.

    Fung, Monica / Babik, Jennifer M

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 72, Issue 2, Page(s) 340–350

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features and ... ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features and outcomes of COVID-19 among immunosuppressed patients, who are at presumed risk of more severe disease but who may also have decreased detrimental inflammatory responses, are not well characterized. We review the existing literature on COVID-19 among immunocompromised populations ranging from patients with cancer and solid-organ transplant recipients to patients with HIV and those receiving immunomodulatory therapy for autoimmune disease. Patients with malignancy and solid-organ transplant recipients may be at increased risk of severe COVID-19 disease and death, whereas for those with other types of immunocompromise, current evidence is less clear. Overall, further prospective controlled studies are needed to determine the attributable risk of immunocompromising conditions and therapies on COVID-19 disease prognosis.
    MeSH term(s) COVID-19 ; Humans ; Immunocompromised Host ; Pandemics ; SARS-CoV-2 ; Transplant Recipients
    Language English
    Publishing date 2021-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1505: Show issues Location:
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  2. Article: Maribavir for Cytomegalovirus Treatment in the Real World-Not a Silver Bullet.

    Fung, Monica / DeVoe, Catherine / Spottiswoode, Natasha / Doernberg, Sarah B

    Open forum infectious diseases

    2022  Volume 10, Issue 1, Page(s) ofac686

    Language English
    Publishing date 2022-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac686
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  3. Article ; Online: Delayed diagnosis and treatment of secondary syphilis in pancreas-kidney transplant recipient: Need for increased awareness of sexually transmitted infections in solid organ transplantation.

    Crossman, Hayley / Guterman, Elan / Fung, Monica

    Transplant infectious disease : an official journal of the Transplantation Society

    2021  Volume 24, Issue 1, Page(s) e13762

    MeSH term(s) Delayed Diagnosis ; HIV Infections ; Humans ; Kidney Transplantation/adverse effects ; Organ Transplantation ; Pancreas ; Sexually Transmitted Diseases/diagnosis ; Sexually Transmitted Diseases/drug therapy ; Syphilis
    Language English
    Publishing date 2021-12-14
    Publishing country Denmark
    Document type Letter
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13762
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5100: Show issues Location:
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  4. Article ; Online: Challenging boundaries: Organ transplants from donors with Listeria central nervous system infections.

    Lueking, Richard / Fung, Monica / Ramos-Salazar, Elizabeth / Katari, Sreelatha / Funk, Geoffrey A / Wolfe, Cameron R / La Hoz, Ricardo M

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2024  

    Abstract: Pretransplant mortality rates in the US remain high and are connected to effective organ donation and utilization. Thus, there is a need to maximize the utilization of available donors. In some cases, this has been safely achieved using organs from ... ...

    Abstract Pretransplant mortality rates in the US remain high and are connected to effective organ donation and utilization. Thus, there is a need to maximize the utilization of available donors. In some cases, this has been safely achieved using organs from donors with infectious complications. For example, several studies describe the use of organs from donors with bacterial meningitis due to pathogens such as Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus influenza, and Escherichia coli, with good outcomes. Listeria is an aerobic and facultatively anaerobic, nonspore-forming, Gram-positive rod that can affect the central nervous system, causing meningitis and meningoencephalitis. Due to its virulence, ability to cause intracellular infection, and lack of clinical data, people dying with listeria may not be evaluated for organ donation, may not have organs recovered, or may have their organs recovered but not transplanted. Herein, we describe the outcomes of 7 solid organ transplant recipients who received organs from 2 donors with Listeria monocytogenes central nervous system infection.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1016/j.ajt.2024.02.025
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    Zs.A 5542: Show issues Location:
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  5. Article ; Online: Solid organ transplant recipients with tuberculosis disease in California, 2010 to 2020.

    Katrak, Shereen / Han, Emily / Readhead, Adam / Fung, Monica / Keh, Chris / Flood, Jennifer / Barry, Pennan

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2023  Volume 23, Issue 3, Page(s) 401–407

    Abstract: Using California Tuberculosis (TB) Registry data from 2010-2020, we compared the presentation and outcomes of patients with TB aged >15 years with and without solid organ transplantation (SOT). We matched to the United Network for Organ Sharing registry ... ...

    Abstract Using California Tuberculosis (TB) Registry data from 2010-2020, we compared the presentation and outcomes of patients with TB aged >15 years with and without solid organ transplantation (SOT). We matched to the United Network for Organ Sharing registry for 1987-2020 and the estimated time from transplantation to the diagnosis of TB, the incidence of posttransplant TB, and the probability of death and graft failure in SOT recipients with TB, compared to those without TB. From 2010-2020, there were 148 posttransplant TB cases. Patients with posttransplant TB were more likely to have extrapulmonary disease and more than twice as likely to die as TB patients without SOT (relative risk [RR], 2.2; 95% confidence interval [CI], 1.6-2.9). The median time from transplantation to TB diagnosis was 1.2 years, with the shortest time among lung transplant recipients. The incidence of TB disease among Californians with SOT was 56.0 per 100 000 person-years. The risk of death was higher among SOT recipients with posttransplant TB than those without (adjusted hazard ratio, 2.8; 95% CI, 2.0-4.1); the risk of graft failure was higher among kidney transplant recipients with posttransplant TB than those without (adjusted hazard ratio, 3.4; 95% CI, 1.7-6.9). An increased risk of death and graft failure in SOT recipients with posttransplant TB highlights the need for enhanced pretransplant TB prevention.
    MeSH term(s) Humans ; Transplant Recipients ; Risk Factors ; Tuberculosis ; Organ Transplantation/adverse effects ; California
    Language English
    Publishing date 2023-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1016/j.ajt.2022.11.019
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    Zs.A 5542: Show issues Location:
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  6. Article ; Online: Focal Nodular Hyperplasia-Like Lesions With Glypican-3 Positivity in Infancy.

    Berklite, Lara / Shenoy, Archana / Hollowell, Monica / Fung, Bonita / Ranganathan, Sarangarajan

    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

    2022  Volume 26, Issue 1, Page(s) 30–38

    Abstract: Purpose and context: Glypican-3 is often used to discriminate between neoplastic and nonneoplastic liver. In focal lesions, positivity may be considered suggestive of a malignancy such as hepatoblastoma. However, glypican-3 is also normally expressed in ...

    Abstract Purpose and context: Glypican-3 is often used to discriminate between neoplastic and nonneoplastic liver. In focal lesions, positivity may be considered suggestive of a malignancy such as hepatoblastoma. However, glypican-3 is also normally expressed in the immature liver. We present a series of 5 cases of focal nodular hyperplasia (FNH)-like lesions arising in very young patients with glypican-3 expression and highlight the challenges these lesions present in the differential diagnosis of hepatoblastoma.
    Methods: Cases were obtained from the files of 3 tertiary pediatric hospitals. Clinical data were obtained from the electronic medical record and histopathologic material including immunohistochemical stains were reviewed.
    Key results: Patients were aged 2 weeks to 6 months with peak AFP levels ranging from 88.6 to 204,696 ng/mL. Microscopically, all were variably demarcated hepatocellular lesions with cords of hepatocytes, marked sinusoidal dilatation, and occasional fibrous bands and areas reminiscent of central scar with bile ducts. No significant cytologic atypia or increased mitotic activity were present. All showed glypican-3 expression and were negative for nuclear beta-catenin with intact reticulin framework.
    Conclusions: Our study highlights the pitfalls of evaluating focal liver lesions in infants when high AFP levels and glypican-3 expression may reflect immaturity rather than neoplasia.
    MeSH term(s) Humans ; Infant ; Child ; Liver Neoplasms/pathology ; Focal Nodular Hyperplasia/diagnosis ; Focal Nodular Hyperplasia/metabolism ; Focal Nodular Hyperplasia/pathology ; Hepatoblastoma/diagnosis ; Glypicans/metabolism ; alpha-Fetoproteins/metabolism ; Liver/pathology ; Diagnosis, Differential
    Chemical Substances Glypicans ; alpha-Fetoproteins
    Language English
    Publishing date 2022-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1463498-3
    ISSN 1615-5742 ; 1093-5266
    ISSN (online) 1615-5742
    ISSN 1093-5266
    DOI 10.1177/10935266221122934
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    Zs.A 5063: Show issues Location:
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  7. Article ; Online: Systematic review for the serological testing for cold agglutinins: The BEST collaborative study.

    Jalink, Marit / Yan, Matthew T S / Cohn, Claudia S / Eichbaum, Quentin G / Fung, Mark K / Lu, Wen / Murphy, Michael F / Pagano, Monica B / Stanworth, Simon J / Shih, Andrew W

    Transfusion

    2024  

    Language English
    Publishing date 2024-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.17842
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    Zs.A 284: Show issues Location:
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  8. Article: Parapharyngeal tuberculoid mass: A rare complication of Bacillus Calmette-Guérin therapy for urothelial carcinoma in situ.

    Plonowska-Hirschfeld, Karolina A / Fung, Monica / Glastonbury, Christine / Ha, Patrick K

    Clinical case reports

    2021  Volume 9, Issue 6, Page(s) e04172

    Abstract: Local and systemic complications of Bacillus Calmette-Guérin therapy are important to recognize as they require prolonged antimicrobial therapy; molecular genomic testing may be key to diagnosis when culture data are inconclusive. ...

    Abstract Local and systemic complications of Bacillus Calmette-Guérin therapy are important to recognize as they require prolonged antimicrobial therapy; molecular genomic testing may be key to diagnosis when culture data are inconclusive.
    Language English
    Publishing date 2021-05-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.4172
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  9. Article ; Online: Multiple social and environmental factors affect wildland fire response of full or less-than-full suppression.

    Daniels, Molly C / Braziunas, Kristin H / Turner, Monica G / Ma, Ting-Fung / Short, Karen C / Rissman, Adena R

    Journal of environmental management

    2024  Volume 351, Page(s) 119731

    Abstract: Wildland fire incident commanders make wildfire response decisions within an increasingly complex socio-environmental context. Threats to human safety and property, along with public pressures and agency cultures, often lead commanders to emphasize full ... ...

    Abstract Wildland fire incident commanders make wildfire response decisions within an increasingly complex socio-environmental context. Threats to human safety and property, along with public pressures and agency cultures, often lead commanders to emphasize full suppression. However, commanders may use less-than-full suppression to enhance responder safety, reduce firefighting costs, and encourage beneficial effects of fire. This study asks: what management, socioeconomic, environmental, and fire behavior characteristics are associated with full suppression and the less-than-full suppression methods of point-zone protection, confinement/containment, and maintain/monitor? We analyzed incident report data from 374 wildfires in the United States northern Rocky Mountains between 2008 and 2013. Regression models showed that full suppression was most strongly associated with higher housing density and earlier dates in the calendar year, along with non-federal land jurisdiction, regional and national incident management teams, human-caused ignitions, low fire-growth potential, and greater fire size. Interviews with commanders provided decision-making context for these regression results. Future efforts to encourage less-than-full suppression should address the complex management context, in addition to the biophysical context, of fire response.
    MeSH term(s) United States ; Humans ; Wildfires ; Fires ; Forecasting ; Risk Management
    Language English
    Publishing date 2024-01-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.119731
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    Z 7556: Show issues

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  10. Article: How Early-Career Scientists Responded with Resiliency to the Space Created by the COVID-19 Pandemic.

    Fung, Fun Man / Jilani, Safia Z / Ohnsorg, Monica L / Pinals, Rebecca L / Saraf, Mohit / Tropp, Joshua / Carlton, Peter

    ACS central science

    2022  Volume 8, Issue 3, Page(s) 294–296

    Language English
    Publishing date 2022-02-14
    Publishing country United States
    Document type Editorial
    ISSN 2374-7943
    ISSN 2374-7943
    DOI 10.1021/acscentsci.2c00094
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