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  1. Article ; Online: Alleviation of Dyspnea and Changes in Physical Activity Level by Air Flow to the Face With a Fan.

    Nagumo, Hideko / Miyagawa, Tetsuo / Sumitani, Mitsuhiro / Fujiwara, Miki / Saito, Hiroko / Takagi, Satoshi / Tsuda, Tohru / Imoto, Hisanori / Ohe, Motoki

    Respiratory care

    2023  Volume 68, Issue 12, Page(s) 1675–1682

    Abstract: Background: Dyspnea is an unpleasant subjective symptom and is associated with decreased physical activity level (PAL). Effect of blowing air toward the face has received a great deal of attention as a symptomatic therapy for dyspnea. However, little is ...

    Abstract Background: Dyspnea is an unpleasant subjective symptom and is associated with decreased physical activity level (PAL). Effect of blowing air toward the face has received a great deal of attention as a symptomatic therapy for dyspnea. However, little is known about the duration of its effect and its impact on PAL. Therefore, this study aimed to measure dyspnea severity and changes in dyspnea and PALs with air blasts to the face.
    Methods: The trial conducted was open-label, randomized, and controlled. This study included out-patients with dyspnea caused by chronic respiratory deficiency. Subjects were provided a small fan and instructed to blow air toward their faces either twice a day or when having trouble breathing. Subsequently, severity of dyspnea and PALs was measured using visual analog scale and physical activity scale for the elderly (PASE), respectively, before and after 3-week treatment. Amounts of changes in dyspnea and PALs before and after treatment were compared using analysis of covariance.
    Results: Overall, 36 subjects were randomized, and 34 were analyzed. Mean age was 75.4 y (26 males [76.5%] and 8 females [23.5%]). Visual analog scale score for dyspnea (SD) before treatment was 33 (13.9) mm and 42 (17.5) mm in the control and intervention groups, respectively. PASE score before treatment was 78.0 (45.1) and 57.7 (38.0) in the control and intervention groups, respectively. No significant difference in changes in dyspnea severity and PAL was observed between the 2 groups.
    Conclusions: No significant difference was observed for dyspnea and PALs in subjects after blowing air toward their own faces with a small fan for 3 weeks at home. Disease variability and impact of protocol violations were high due to small number of cases. Further studies with a design focused on subject protocol adherence and measurement methods are required to understand impact of air flow on dyspnea and PAL.
    MeSH term(s) Male ; Female ; Humans ; Aged ; Palliative Care ; Exercise ; Dyspnea/etiology ; Dyspnea/therapy
    Language English
    Publishing date 2023-11-25
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.10715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Emergent transcatheter arterial embolization to control critical blood pressure fluctuation associated with hypercatecholaminemic crisis in a patient with an unruptured retroperitoneal paraganglioma.

    Kariyasu, Toshiya / Machida, Haruhiko / Nishina, Yoshio / Tambo, Mitsuhiro / Miyagawa, Shogo / Rakue, Takayuki / Sumitani, Yoshikazu / Yasuda, Kazuki / Shibahara, Junji / Yokoyama, Kenichi

    Radiology case reports

    2021  Volume 16, Issue 8, Page(s) 2065–2071

    Abstract: Pheochromocytoma/paraganglioma (PPGL)-related hypercatecholaminemic crisis is a rare lethal condition caused by uncontrolled catecholamine secretion, occasionally leading to critical fluctuation in blood pressure (BP). Emergent transcatheter arterial ... ...

    Abstract Pheochromocytoma/paraganglioma (PPGL)-related hypercatecholaminemic crisis is a rare lethal condition caused by uncontrolled catecholamine secretion, occasionally leading to critical fluctuation in blood pressure (BP). Emergent transcatheter arterial embolization (TAE) has been employed for spontaneous PPGL rupture, but never, to our knowledge, for critical fluctuation in BP associated with PPGL-related hypercatecholaminemic crisis. We describe here our experience utilizing this method to control critical fluctuation in BP associated with this crisis in a 44-year-old man with an unruptured retroperitoneal paraganglioma. The patient experienced sudden severe left abdominal pain and came to our emergency department, where he exhibited severe fluctuation in BP and underwent laboratory testing that showed hypercatecholaminuria and computed tomography (CT) that revealed a left retroperitoneal tumor with no apparent intra- or retroperitoneal hematoma. We performed emergent TAE from the left inferior phrenic artery using gelatin sponge, which stabilized his BP and relieved his abdominal pain. Histologic examination following elective surgical resection of the tumor confirmed our diagnosis of unruptured retroperitoneal paraganglioma. We believe that TAE represents an important option for the emergent treatment of the critical BP fluctuation associated with PPGL-related hypercatecholaminemic crisis.
    Language English
    Publishing date 2021-06-08
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2021.05.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Emergent transcatheter arterial embolization to control critical blood pressure fluctuation associated with hypercatecholaminemic crisis in a patient with an unruptured retroperitoneal paraganglioma

    Toshiya Kariyasu / Haruhiko Machida / Yoshio Nishina / Mitsuhiro Tambo / Shogo Miyagawa / Takayuki Rakue / Yoshikazu Sumitani / Kazuki Yasuda / Junji Shibahara / Kenichi Yokoyama

    Radiology Case Reports, Vol 16, Iss 8, Pp 2065-

    2021  Volume 2071

    Abstract: Pheochromocytoma/paraganglioma (PPGL)-related hypercatecholaminemic crisis is a rare lethal condition caused by uncontrolled catecholamine secretion, occasionally leading to critical fluctuation in blood pressure (BP). Emergent transcatheter arterial ... ...

    Abstract Pheochromocytoma/paraganglioma (PPGL)-related hypercatecholaminemic crisis is a rare lethal condition caused by uncontrolled catecholamine secretion, occasionally leading to critical fluctuation in blood pressure (BP). Emergent transcatheter arterial embolization (TAE) has been employed for spontaneous PPGL rupture, but never, to our knowledge, for critical fluctuation in BP associated with PPGL-related hypercatecholaminemic crisis. We describe here our experience utilizing this method to control critical fluctuation in BP associated with this crisis in a 44-year-old man with an unruptured retroperitoneal paraganglioma. The patient experienced sudden severe left abdominal pain and came to our emergency department, where he exhibited severe fluctuation in BP and underwent laboratory testing that showed hypercatecholaminuria and computed tomography (CT) that revealed a left retroperitoneal tumor with no apparent intra- or retroperitoneal hematoma. We performed emergent TAE from the left inferior phrenic artery using gelatin sponge, which stabilized his BP and relieved his abdominal pain. Histologic examination following elective surgical resection of the tumor confirmed our diagnosis of unruptured retroperitoneal paraganglioma. We believe that TAE represents an important option for the emergent treatment of the critical BP fluctuation associated with PPGL-related hypercatecholaminemic crisis.
    Keywords Critical blood pressure fluctuation ; Emergent transcatheter arterial embolization ; Hypercatecholaminemic crisis ; Retroperitoneal paraganglioma ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Mediastinal peripheral T-cell lymphoma diagnosed by repeated biopsies after an initial diagnosis of fibrosing mediastinitis.

    Kakuta, Naoko / Sumitani, Mitsuhiro / Sugitani, Arata / Nakahama, Kenji / Miki, Yuzo / Syoji, Seichi

    Respirology case reports

    2017  Volume 5, Issue 6, Page(s) e00272

    Abstract: We report a case of mediastinal peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) diagnosed by repeated biopsies. A 44-year-old man was admitted to our hospital with a 2-week history of facial swelling, neck distension, and dyspnoea on ... ...

    Abstract We report a case of mediastinal peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) diagnosed by repeated biopsies. A 44-year-old man was admitted to our hospital with a 2-week history of facial swelling, neck distension, and dyspnoea on exertion. Computed tomography of the chest showed a mediastinal mass. Initial needle biopsy and video-assisted thoracoscopic biopsy revealed the pathological diagnosis of fibrosing mediastinitis (FM). Glucocorticoid therapy (prednisolone) was temporarily effective in reducing tumour size. However, other laboratory features suggested that the diagnosis of FM might not be correct. After repeated biopsies, we established the diagnosis of mediastinal PTCL-NOS. With this correct diagnosis, appropriate therapy for PTCL resulted in the improvement of the clinical manifestations. This report suggests that the presence of malignant lymphoma should be considered in cases of mediastinal tumours, and repeated biopsies may be occasionally needed for consistent diagnosis.
    Language English
    Publishing date 2017-09-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2750180-2
    ISSN 2051-3380
    ISSN 2051-3380
    DOI 10.1002/rcr2.272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Multi-Institutional Prospective Cohort Study of Patients With Pulmonary Hypertension Associated With Respiratory Diseases.

    Tanabe, Nobuhiro / Kumamaru, Hiraku / Tamura, Yuichi / Taniguchi, Hiroyuki / Emoto, Noriaki / Yamada, Yoshihito / Nishiyama, Osamu / Tsujino, Ichizo / Kuraishi, Hiroshi / Nishimura, Yoshihiro / Kimura, Hiroshi / Inoue, Yoshikazu / Morio, Yoshiteru / Nakatsumi, Yasuto / Satoh, Toru / Hanaoka, Masayuki / Kusaka, Kei / Sumitani, Mitsuhiro / Handa, Tomohiro /
    Sakao, Seiicihiro / Kimura, Tomoki / Kondoh, Yasuhiro / Nakayama, Kazuhiko / Tanaka, Kensuke / Ohira, Hiroshi / Nishimura, Masaharu / Miyata, Hiroaki / Tatsumi, Koichiro

    Circulation journal : official journal of the Japanese Circulation Society

    2021  Volume 85, Issue 4, Page(s) 333–342

    Abstract: Background: There is limited evidence for pulmonary arterial hypertension (PAH)-targeted therapy in patients with pulmonary hypertension associated with respiratory disease (R-PH). Therefore, we conducted a multicenter prospective study of patients with ...

    Abstract Background: There is limited evidence for pulmonary arterial hypertension (PAH)-targeted therapy in patients with pulmonary hypertension associated with respiratory disease (R-PH). Therefore, we conducted a multicenter prospective study of patients with R-PH to examine real-world characteristics of responders by evaluating demographics, treatment backgrounds, and prognosis.Methods and Results:Among the 281 patients with R-PH included in this study, there was a treatment-naïve cohort of 183 patients with normal pulmonary arterial wedge pressure and 1 of 4 major diseases (chronic obstructive pulmonary diseases, interstitial pneumonia [IP], IP with connective tissue disease, or combined pulmonary fibrosis with emphysema); 43% of patients had mild ventilatory impairment (MVI), whereas 52% had a severe form of PH. 68% received PAH-targeted therapies (mainly phosphodiesterase-5 inhibitors). Among patients with MVI, those treated initially (i.e., within 2 months of the first right heart catheterization) had better survival than patients not treated initially (3-year survival 70.6% vs. 34.2%; P=0.01); there was no significant difference in survival in the group with severe ventilatory impairment (49.6% vs. 32.1%; P=0.38). Responders to PAH-targeted therapy were more prevalent in the group with MVI.
    Conclusions: This first Japanese registry of R-PH showed that a high proportion of patients with MVI (PAH phenotype) had better survival if they received initial treatment with PAH-targeted therapies. Responders were predominant in the group with MVI.
    MeSH term(s) Familial Primary Pulmonary Hypertension ; Humans ; Hypertension, Pulmonary/complications ; Hypertension, Pulmonary/drug therapy ; Japan ; Lung Diseases, Interstitial/complications ; Lung Diseases, Interstitial/drug therapy ; Prospective Studies ; Respiration Disorders/complications ; Respiration Disorders/drug therapy
    Language English
    Publishing date 2021-02-02
    Publishing country Japan
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-20-0939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Additive inoculation of influenza vaccine and 23-valent pneumococcal polysaccharide vaccine to prevent lower respiratory tract infections in chronic respiratory disease patients.

    Sumitani, Mitsuhiro / Tochino, Yoshihiro / Kamimori, Takao / Fujiwara, Hiroshi / Fujikawa, Terumichi

    Internal medicine (Tokyo, Japan)

    2008  Volume 47, Issue 13, Page(s) 1189–1197

    Abstract: Background: An increased incidence of pneumococcal infection triggered by influenza infection has been reported.: Objective: To examine the effectiveness of the additive inoculation of influenza vaccine (I-V) and 23-valent pneumococcal vaccine (P-V) ... ...

    Abstract Background: An increased incidence of pneumococcal infection triggered by influenza infection has been reported.
    Objective: To examine the effectiveness of the additive inoculation of influenza vaccine (I-V) and 23-valent pneumococcal vaccine (P-V) to prevent lower respiratory tract infections.
    Methods: 105 Japanese patients with chronic respiratory disease underwent the additive inoculation of I-V and P-V between October 2002 and January 2003, and their medical records were used to retrospectively examine the number of bacterial respiratory infections, number of hospitalizations, and length of hospital stay in the 2 years prior to and after P-V inoculation. Among them [chronic obstructive pulmonary disease (COPD): 45; bronchial asthma: 24; bronchiectasis: 20 (including diffuse panbronchiolitis); and other diseases: 16], 98 patients were evaluated, except for seven patients who died of diseases other than respiratory infections within the 2 years after P-V inoculation. Subjects were 51 to 91 years of age (median: 74 yrs), the male-female ratio was 63:42, and 32 patients were on home oxygen therapy.
    Results: After P-V inoculation, decreases in the number of respiratory infections (3.16 vs. 1.95 infections; p=0.0004) and in the number of hospitalizations (0.79 vs. 0.43 hospitalizations; p=0.001) were observed. Furthermore, an analysis including other factors, i.e., number of patients on home oxygen therapy and influenza season, also revealed a decreased number of hospitalizations.
    Conclusions: The additive inoculation of I-V and P-V in Japanese patients with chronic respiratory disease prevented the development of bacterial respiratory infections and warrants further study in patients with respiratory disease.
    MeSH term(s) Aged ; Aged, 80 and over ; Community-Acquired Infections/prevention & control ; Female ; Humans ; Immunization Schedule ; Influenza Vaccines ; Longitudinal Studies ; Lung Diseases, Obstructive/complications ; Male ; Middle Aged ; Pneumococcal Vaccines ; Pneumonia, Bacterial/prevention & control ; Retrospective Studies
    Chemical Substances 23-valent pneumococcal capsular polysaccharide vaccine ; Influenza Vaccines ; Pneumococcal Vaccines
    Language English
    Publishing date 2008-07-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.47.0799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [A case of a septic pulmonary embolism-related implanted central venous port].

    Okada, Hideaki / Taira, Koichi / Tokunaga, Shinya / Daga, Haruko / Tsuda, Manabu / Miyamoto, Natsuko / Nishijima, Masayoshi / Sumitani, Mitsuhiro / Syoji, Seiichi / Takeda, Koji

    Gan to kagaku ryoho. Cancer & chemotherapy

    2013  Volume 40, Issue 3, Page(s) 389–392

    Abstract: We report a case of a 32-year-old woman with a septic pulmonary embolism-related implanted central venous port. She was treated with S-1/cisplatin(CDDP)chemotherapy for recurrent gastric cancer. Her disease was progressive after five courses of S-1/CDDP ... ...

    Abstract We report a case of a 32-year-old woman with a septic pulmonary embolism-related implanted central venous port. She was treated with S-1/cisplatin(CDDP)chemotherapy for recurrent gastric cancer. Her disease was progressive after five courses of S-1/CDDP combination therapy. Because of peritonitis carcinomatosa, her oral intake was poor, so we placed an implanted central venous port in her right subclavian vein. We administered 5-FU/Leucovorin/paclitaxel combination therapy and total parenteral nutrition from the port. Chemotherapy was effective, so we stopped total parenteral nutrition after one month. Two months later, multiple nodular shadows appeared in her left lung fields without apparent symptoms. Because we suspected septic pulmonary embolism related to the venous port, we removed the venous port promptly and administered antibiotics with a broad spectrum. Pulmonary shadows disappeared immediately, and no recurrence was observed afterward.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Catheterization, Central Venous/adverse effects ; Catheters, Indwelling/adverse effects ; Cisplatin/administration & dosage ; Drug Combinations ; Female ; Humans ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/surgery ; Oxonic Acid/administration & dosage ; Pulmonary Embolism/etiology ; Sepsis/complications ; Sepsis/drug therapy ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/surgery ; Tegafur/administration & dosage
    Chemical Substances Drug Combinations ; S 1 (combination) (150863-82-4) ; Tegafur (1548R74NSZ) ; Oxonic Acid (5VT6420TIG) ; Cisplatin (Q20Q21Q62J)
    Language Japanese
    Publishing date 2013-03
    Publishing country Japan
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 604842-0
    ISSN 0385-0684
    ISSN 0385-0684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [A case of sarcoidosis who showed rapid swelling of mediastinal and abdominal lymph nodes].

    Hasegawa, Yoshikazu / Kawano, Yuu / Sumitani, Mitsuhiro / Takeda, Kouji / Kashii, Tatsuhiko / Takihuji, Nobuhide / Terakawa, Kazuhiko

    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society

    2007  Volume 45, Issue 1, Page(s) 54–58

    Abstract: A 49-year-old woman noticed hoarseness and facial palsey three months prior to her visit to our hospital. Chest radiograph and CT scanning revealed bilateral mediastinal and hilar lymphadenopathy. Bronchofiberoptic biopsy showed sarcoidosis. Her symptoms ...

    Abstract A 49-year-old woman noticed hoarseness and facial palsey three months prior to her visit to our hospital. Chest radiograph and CT scanning revealed bilateral mediastinal and hilar lymphadenopathy. Bronchofiberoptic biopsy showed sarcoidosis. Her symptoms improved under no treatment. However, she showed rapid increase of mediastinal and abdominal lymph nodes swelling and elevation of serum level of sIL-2R during observation. Therefore, we must discriminate sarcoidosis-lymphoma syndrome from exacerbation of sarcoidosis. Mediastinoscopic biopsy was conducted for diagnosis, and it revealed exacerbation of sarcoidosis. We reported this rare case of rapid increase of mediastinal and abdominal lymph node swelling due to sarcoidosis.
    MeSH term(s) Abdomen ; Aged ; Biopsy ; Edema/etiology ; Edema/pathology ; Female ; Humans ; Lymph Nodes/pathology ; Lymphatic Diseases/pathology ; Mediastinoscopy ; Mediastinum/pathology ; Sarcoidosis/pathology
    Language Japanese
    Publishing date 2007-01
    Publishing country Japan
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 1456536-5
    ISSN 1345-9538 ; 1343-3490
    ISSN (online) 1345-9538
    ISSN 1343-3490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Case of Toxocara canis larva migrans cured by additional treatment with albendazole].

    Takamatsu, Kazufumi / Sumitani, Mitsuhiro / Nanjyou, Shigeki / Nishijima, Masayoshi / Syoji, Seiichi / Takifuji, Nobuhide / Kiyota, Hidemi / Daga, Haruko / Takeda, Koji

    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society

    2008  Volume 46, Issue 10, Page(s) 836–841

    Abstract: A 42-year-old man presented at our emergency department with fever, sputum, and dyspnea. His chest X-ray films showed ground-glass opacities mainly in the upper and middle lung fields. We diagnosed pneumonia, gave antibiotic treatment, and his symptoms ... ...

    Abstract A 42-year-old man presented at our emergency department with fever, sputum, and dyspnea. His chest X-ray films showed ground-glass opacities mainly in the upper and middle lung fields. We diagnosed pneumonia, gave antibiotic treatment, and his symptoms improved. However he later showed eosinophilia. We performed additional workup, and diagnosed Toxocara canis larva migrans. We treated him with albendazole for four weeks, but his eosinophil count rose again from the end of treatment one month later. Therefore we performed additional treatment with albendazole for 8 weeks, after which the clinical imaging findings and serum antibody titer improved. There are few reports about additional treatment for Toxocara canis larva migrans, and there is not yet a consensus. We think that we should consider additional treatment in cases that do not show improvement on initial treatment.
    MeSH term(s) Adult ; Albendazole/administration & dosage ; Animals ; Anthelmintics/administration & dosage ; Dogs ; Humans ; Larva Migrans, Visceral/diagnosis ; Larva Migrans, Visceral/drug therapy ; Male ; Pulmonary Eosinophilia/drug therapy ; Pulmonary Eosinophilia/etiology ; Toxocara canis ; Treatment Outcome
    Chemical Substances Anthelmintics ; Albendazole (F4216019LN)
    Language Japanese
    Publishing date 2008-10
    Publishing country Japan
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 1456536-5
    ISSN 1345-9538 ; 1343-3490
    ISSN (online) 1345-9538
    ISSN 1343-3490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Clinical relevance of sputum cytology and chest X-ray in patients with suspected lung tumors.

    Sumitani, Mitsuhiro / Takifuji, Nobuhide / Nanjyo, Shigeki / Imahashi, Yumiko / Kiyota, Hidemi / Takeda, Koji / Yamamoto, Ryoji / Tada, Hirohito

    Internal medicine (Tokyo, Japan)

    2008  Volume 47, Issue 13, Page(s) 1199–1205

    Abstract: Objective: To review diagnostic procedures, therapeutic modalities, and follow-up methods in patients with suspected lung tumors.: Methods: We retrospectively examined 70 patients who underwent a complete medical checkup because they had been ... ...

    Abstract Objective: To review diagnostic procedures, therapeutic modalities, and follow-up methods in patients with suspected lung tumors.
    Methods: We retrospectively examined 70 patients who underwent a complete medical checkup because they had been positive for sputum cytology and had presented no chest X-ray findings for the 10-year period between 1994 and 2004. To make a diagnosis, we conducted the first complete medical checkup that included chest X-ray, sputum cytology, chest computed tomography (CT), and bronchoscopy. In the case that no diagnosis could be made, we repeated the chest X-ray and sputum cytology every 3 to 6 months and additionally conducted chest CT and bronchoscopy according to abnormal findings.
    Results: Among 70 patients, there were 36 and 13 who were diagnosed during the first complete medical checkup and follow-up, respectively, 13 who remained undiagnosed, and eight for whom follow-up was discontinued. Among the 49 diagnosed patients, 40, 8, and 1 patient had lung cancer, upper respiratory tract carcinoma (URTC), and esophageal carcinoma (EC), respectively. Among the 40 patients with lung cancer, 34 had a stage 0 or I tumor and 15 were radically treatable by photodynamic therapy and endobronchial irradiation. Nine among 11 patients whose lung cancer was detected during follow-up had a stage 0 or IA tumor.
    Conclusion: Not only lung cancer but also URTC and EC were successfully detected in patients who were positive for sputum cytology and presented negative chest X-ray. Radical treatment was possible in 38 (76%) of 50 diagnosed patients, thus indicating the importance of follow-up through these procedures.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Bronchoscopy ; Early Diagnosis ; Female ; Histocytochemistry ; Humans ; Japan ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Male ; Mass Chest X-Ray ; Middle Aged ; Photochemotherapy ; Retrospective Studies ; Sputum/cytology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2008-07-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.47.0777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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