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  1. Article ; Conference proceedings: Reports from the 17th Acute Disease Quality Initiative (ADQI) Consensus Consensus Conference on CRRT

    Kellum, John A.

    Blood purification 42, 3 , Seite 221-278

    Asiago, Italy, June 10-13, 2016

    2016  

    Event/congress Acute Disease Quality Initiative (ADQI) Consensus Conference on CRRT (17., 2016, Asiago)
    Author's details chairmen John A. Kellum, Claudio Ronco
    Collection Blood purification
    Language English
    Dates of publication 2016-9999
    Size Illustrationen
    Publishing place Basel, [2016]
    Publishing country Switzerland
    Document type Article ; Conference proceedings
    HBZ-ID HT019105222
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Zs A 1872 -42-

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  2. Book: Nephrology

    Kellum, John A.

    (Critical care clinics ; 31,4)

    2015  

    Author's details ed. John A. Kellum
    Series title Critical care clinics ; 31,4
    Collection
    Language English
    Size XV S., S. 622 - 866 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018820328
    ISBN 978-0-323-40078-7 ; 0-323-40078-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Se 990 -31,4- verfügbar in Königswinter Königswinter

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  3. Article ; Online: The authors reply.

    Gomez, Hernando / Kellum, John A

    Critical care medicine

    2023  Volume 51, Issue 2, Page(s) e61

    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Double the risk of death and other 'inconvenient truths' about oliguria.

    Kellum, John A / Murugan, Raghavan

    Intensive care medicine

    2023  Volume 49, Issue 11, Page(s) 1420–1421

    MeSH term(s) Humans ; Oliguria/etiology
    Language English
    Publishing date 2023-08-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-023-07187-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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  5. Article ; Online: Do Novel Biomarkers Have Utility in the Diagnosis and Prognosis of AKI? PRO.

    Kellum, John A / Goldstein, Stuart L

    Kidney360

    2023  Volume 4, Issue 12, Page(s) 1663–1666

    MeSH term(s) Humans ; Prognosis ; Biomarkers ; Acute Kidney Injury/diagnosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Journal Article
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Controversies in acute kidney injury

    Kellum, John A.

    16 tables

    (Contributions to nephrology ; 174)

    2011  

    Author's details vol. ed. John A. Kellum
    Series title Contributions to nephrology ; 174
    Collection
    Keywords Acute Kidney Injury / physiopathology ; Acute Kidney Injury / therapy ; Renal Replacement Therapy ; Nierenversagen ; Hämodialyse ; Nierentransplantation
    Subject Niere ; Blutdialyse ; Blutwäsche ; Akute Niereninsuffizienz ; Akutes Nierenversagen ; Akute Nierenschädigung
    Subject code 617.461044
    Language English
    Size VII, 258 S. : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland ; Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT017025426
    ISBN 978-3-8055-9810-1 ; 3-8055-9810-6 ; 9783805598118 ; 3805598114
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2011 A 4613 order for loan Magazin

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  7. Article ; Online: Endotoxic Septic Shock: Diagnosis and Treatment.

    Foster, Debra M / Kellum, John A

    International journal of molecular sciences

    2023  Volume 24, Issue 22

    Abstract: Endotoxin, also referred to as lipopolysaccharide (LPS), is a potent stimulator of the inflammatory cascade which may progress to sepsis and septic shock. The term endotoxic septic shock has been used for patients who have a clinical phenotype that is ... ...

    Abstract Endotoxin, also referred to as lipopolysaccharide (LPS), is a potent stimulator of the inflammatory cascade which may progress to sepsis and septic shock. The term endotoxic septic shock has been used for patients who have a clinical phenotype that is characterized by high endotoxin activity in addition to a high burden of organ failure; especially a pattern of organ failure including hepatic dysfunction, acute kidney injury, and various forms of endothelial dysfunction. Endotoxic septic shock has been a target for drug therapy for decades with no success. A likely barrier to their success was the inability to quantify endotoxin in the bloodstream. The Endotoxin Activity Assay (EAA) is positioned to change this landscape. In addition, medical devices using adsorptive technology in an extra-corporeal circulation has been shown to remove large quantities of endotoxin from the bloodstream. Focusing on the use of EAA to determine high concentrations of endotoxin will allow patients with endotoxic septic shock to be identified quickly and these patients may benefit most from removal of endotoxin using extracorporeal methods.
    MeSH term(s) Humans ; Shock, Septic/therapy ; Shock, Septic/drug therapy ; Sepsis ; Endotoxins ; Lipopolysaccharides
    Chemical Substances Endotoxins ; Lipopolysaccharides
    Language English
    Publishing date 2023-11-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242216185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The role of endotoxin in septic shock.

    Kellum, John A / Ronco, Claudio

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 400

    Abstract: Septic shock can be caused by a variety of mechanisms including direct effects of bacterial toxins such as endotoxin. Annually, approximately 5-7 million patients worldwide develop sepsis with very high endotoxin activity in the blood and more than half ... ...

    Abstract Septic shock can be caused by a variety of mechanisms including direct effects of bacterial toxins such as endotoxin. Annually, approximately 5-7 million patients worldwide develop sepsis with very high endotoxin activity in the blood and more than half die. The term endotoxic septic shock has been used for these patients but it is important to emphasize that endotoxin may be a factor in all forms of septic shock including non-bacterial etiologies like COVID-19 since translocation of bacterial products is a common feature of septic shock. A pattern of organ failure including hepatic dysfunction, acute kidney injury and various forms of endothelial dysfunction ranging from disseminated intravascular coagulation to thrombotic microangiopathy characterize endotoxic septic shock. However, while characteristic, the clinical phenotype is not unique to patients with high endotoxin, and the diagnosis relies on the measurement of endotoxin activity in addition to clinical assessment. Therapies for endotoxic septic shock are limited with immune modulating therapies under investigation and extracorporeal blood purification still controversial in many parts of the world.
    MeSH term(s) Humans ; Shock, Septic ; Endotoxins ; COVID-19/complications ; Sepsis
    Chemical Substances Endotoxins
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04690-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Continuous renal replacement therapy

    Kellum, John A. / Bellomo, Rinaldo / Ronco, Claudio

    (Pittsburgh critical care medicine series)

    2016  

    Author's details edited by John A. Kellum, Rinaldo Bellomo, Claudio Ronco
    Series title Pittsburgh critical care medicine series
    Keywords Acute renal failure/Treatment ; Continuous arteriovenous hemofiltration ; Hemodialysis
    Subject code 616.61406
    Language English
    Size XV, 306 S. : Ill., graph. Darst., 21 cm
    Edition 2. ed.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018923650
    ISBN 978-0-19-022553-7 ; 0-19-022553-X
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2016 A 720 available for loan (reading room) Lesesaal EG

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  10. Article ; Online: Impact of Consensus Papers versus Randomized Trials in Critical Care Nephrology.

    Kellum, John A

    Blood purification

    2020  Volume 49, Issue 6, Page(s) 708–712

    Abstract: Introduction: Reports of consensus conferences are usually valued less than reports of clinical trials even when rigorous methodology is used. However, limited data are available comparing the impact of these 2 methods of shaping clinical practice.: ... ...

    Abstract Introduction: Reports of consensus conferences are usually valued less than reports of clinical trials even when rigorous methodology is used. However, limited data are available comparing the impact of these 2 methods of shaping clinical practice.
    Objective: Compare the publication impact of consensus conferences and clinical trials.
    Methods: Consensus publications from the Acute Disease Quality Initiative (ADQI) from 2002 through 2017 were identified and classified by subject matter. Randomized trials were identified in the same publication year and subject in journals, starting with the highest impact factor. Both publication types were matched, and total citations were determined for each using Google Scholar. A secondary analysis compared total costs for each publication type.
    Results and conclusions: Seventeen ADQI consensus conference reports and 17 randomized trials were identified. ADQI reports received a similar number of citations per paper (median, interquartile range) compared to randomized trials (132, 54-228; vs. 159, 60-340, p = ns). Similarly, 10 (58.8%) ADQI reports and 10 randomized trials were cited >100 times. On average, ADQI reports appeared in journals with lower impact factors compared to clinical trials (5.4 ± 4.6 vs. 25.4 ± 27.1; p < 0.01). The median cost per citation (USD 2017) for ADQI reports was USD 606.01 compared to almost twice this figure, USD 1,182.59, for clinical trials on the same topics (p = 0.09). Despite being published in lower impact factor journals, consensus reports on topics in critical care nephrology, received similar citations to randomized controlled trials published the same year.
    MeSH term(s) Acute Disease ; Consensus Development Conferences as Topic ; Critical Care/methods ; Humans ; Kidney Diseases/diagnosis ; Kidney Diseases/etiology ; Kidney Diseases/therapy ; Nephrology/methods ; Nephrology/standards ; Randomized Controlled Trials as Topic/standards
    Language English
    Publishing date 2020-04-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 605548-5
    ISSN 1421-9735 ; 0253-5068
    ISSN (online) 1421-9735
    ISSN 0253-5068
    DOI 10.1159/000507422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1872: Show issues Location:
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