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  1. Article: Revealing the novel effect of Jinghua Weikang capsule against the antibiotic resistance of

    Jia, Xiaofen / Huang, Qiuyue / Lin, Miaomiao / Chu, Yingming / Shi, Zongming / Zhang, Xuezhi / Ye, Hui

    Frontiers in microbiology

    2022  Volume 13, Page(s) 962354

    Abstract: Background: Helicobacter pylori: Method: The agar plate dilution method, E-test method, and killing kinetics assay were used to evaluate the bactericidal effect of JWC on antibiotic-resistant : Results: JWC showed considerable antibacterial ... ...

    Abstract Background: Helicobacter pylori
    Method: The agar plate dilution method, E-test method, and killing kinetics assay were used to evaluate the bactericidal effect of JWC on antibiotic-resistant
    Results: JWC showed considerable antibacterial activity against drug-resistant
    Conclusion: The reversal of MTZ resistance by JWC may be achieved through the adhesin/efflux pump-biofilm pathway.
    Language English
    Publishing date 2022-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.962354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Jinghua Weikang capsule protects against Helicobacter pylori-induced inflammatory responses via the nuclear factor-kappa B signaling pathway.

    Shi, Zongming / Ye, Hui / Yu, Jing / Zhang, Xuezhi / Cheng, Hong / Li, Jiang

    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

    2020  Volume 38, Issue 3, Page(s) 366–372

    Abstract: Objective: To investigate the inhibitory effect of Jinghua Weikang capsule (JWC) on gastric ...

    Abstract Objective: To investigate the inhibitory effect of Jinghua Weikang capsule (JWC) on gastric inflammation induced by Helicobacter pylori (H. pylori) via the nuclear factor-kappa B (NF-¦ÊB) signaling pathway in Kunming mice.
    Methods: We investigated the anti-inflammation potential of JWC extract in vivo in a H. pylori-induced gastritis mouse model. The expression of inflammation-related molecules was evaluated by Western blotting, and the concentrations of in vivo inflammatory markers were measured by enzyme-linked immunosorbent assay. Inflammatory cell infiltration was evaluated by histopathological examination, and mRNA levels of related genes were evaluated by quantitative reverse transcription polymerase chain reaction.
    Results: JWC had a dose-dependent protective effect against H. pylori-induced gastritis by protecting gastric epithelial cells and inhibiting inflammatory cell infiltration. Mechanistically, JWC decreased the protein levels of phosphorylated I¦ÊB¦Á and NF-¦ÊB p65, mRNA levels of NF-¦ÊB pathway molecules, and plasma levels of tumor necrosis factor-¦Á and interleukin 1 beta.
    Conclusion: An important finding of our study is that JWC attenuated gastrointestinal inflammation and ulceration and exerted a protective effect against gastric injury via inhibition of inflammation reactions and regulating the canonical NF-κB signaling pathway in vivo.
    Language English
    Publishing date 2020-03-10
    Publishing country China
    Document type Journal Article
    ZDB-ID 603186-9
    ISSN 2589-451X ; 0254-6272 ; 0255-2922
    ISSN (online) 2589-451X ; 0254-6272
    ISSN 0255-2922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: In vitro bactericidal activity of Jinghua Weikang Capsule and its individual herb Chenopodium ambrosioides L. against antibiotic-resistant Helicobacter pylori.

    Liu, Wei / Liu, Yu / Zhang, Xue-Zhi / Li, Ning / Cheng, Hong

    Chinese journal of integrative medicine

    2012  Volume 19, Issue 1, Page(s) 54–57

    Abstract: Objective: To investigate the bactericidal effects of Jinghua Weikang Capsule and its major ... Jinghua Weikang Capsule or Chenopodium ambrosioides L. By means of time-kill curve method, the average ... the time-kill curves were charted.: Results: Both Jinghua Weikang Capsule and Chenopodium ambrosioides L ...

    Abstract Objective: To investigate the bactericidal effects of Jinghua Weikang Capsule and its major component Chenopodium ambrosioides L. on antibiotic-resistant Helicobacter pylori.
    Methods: Four clinical antibiotic-resistant H. pylori strains were isolated and incubated in liquid medium containing Jinghua Weikang Capsule or Chenopodium ambrosioides L. By means of time-kill curve method, the average colony counts and bactericidal rate were calculated at time points of 0, 4, 8 and 24 h after the incubation and the time-kill curves were charted.
    Results: Both Jinghua Weikang Capsule and Chenopodium ambrosioides L. at a concentration of 0.64 g/L showed obvious bactericidal effect against antibiotic-resistant H. pylori after 4 h of incubation.
    Conclusion: Jinghua Weikang Capsule and Chenopodium ambrosioides L. are considered to be active against antibiotic-resistant H. pylori in vitro.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Chenopodium ambrosioides ; Drug Resistance, Microbial ; Drugs, Chinese Herbal/pharmacology ; Helicobacter Infections/drug therapy ; Helicobacter Infections/physiopathology ; Helicobacter pylori/drug effects ; Helicobacter pylori/isolation & purification ; Humans ; In Vitro Techniques ; Microbial Sensitivity Tests ; Plant Preparations/pharmacology ; Sensitivity and Specificity
    Chemical Substances Anti-Bacterial Agents ; Drugs, Chinese Herbal ; Plant Preparations ; jinghua weikang
    Language English
    Publishing date 2012-12-29
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-012-1248-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Party membership and self-assessed health: Evidence from the Communist Party of China.

    Zhang, Pengfei / Gao, Jinghua

    SSM - population health

    2024  Volume 25, Page(s) 101631

    Abstract: Background: In some countries, party membership is often associated with returns. We studied the relationship between party membership and self-assessed health.: Methods: Data were obtained from the 2017 Chinese General Social Survey (N = 11,641). ... ...

    Abstract Background: In some countries, party membership is often associated with returns. We studied the relationship between party membership and self-assessed health.
    Methods: Data were obtained from the 2017 Chinese General Social Survey (N = 11,641). Self-assessed health was defined as the personal evaluation of physical and psychological well-being. Logistic regression was used to explore relevant associations.
    Results: Members of the Communist Party of China (CPC) were more likely than non-CPC respondents to register self-assessments of relatively healthy physical (beta = 0.319, SE = 0.098, P < 0.01, CI: 0.127-0.512) and psychological (beta = 0.257, SE = 0.072, P < 0.01, CI: 0.115-0.399) conditions.
    Conclusions: Previous studies have overlooked the health-related rewards of CPC membership. Reforms to China's public health system can be smoothly implemented probably because of the health benefits accrued to party members.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ISSN 2352-8273
    ISSN 2352-8273
    DOI 10.1016/j.ssmph.2024.101631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pollution Transfer under Intergovernmental Competition

    Hongmin Zhang / Jinghua Zhang

    Sustainability, Vol 15, Iss 21, p

    Suppression or Opportunity

    2023  Volume 15363

    Abstract: In recent years, the Sustainable Development Goals have introduced a “race to the top” mechanism to complement the “race to the bottom” in local governance and have an impact on pollution. This study utilizes the environmentally oriented accreditation of ...

    Abstract In recent years, the Sustainable Development Goals have introduced a “race to the top” mechanism to complement the “race to the bottom” in local governance and have an impact on pollution. This study utilizes the environmentally oriented accreditation of National Civilized Cities as a policy shock and applies the PSM-DID method to identify the pollution-relocation effects among cities triggered by the competition in local governance. The results indicate that environmentally oriented intergovernmental competition leads to the transfer of industrial enterprises to non-accredited cities, resulting in a significant increase in their pollution emissions and industrial pollution intensity. This indicates that the competition in asymmetric local governance will lead to the transfer of pollution to backward regions, which hampers the overall implementation efficiency of national environmental policies. Furthermore, heterogeneity analysis reveals that the impact is more significant for cities in the central and western regions. Being nominated for the National Civilized City accreditation helps to inhibit the influx of polluting enterprises. Cities that are not part of integrated environmental regulatory regions show a more pronounced increase in pollution emissions compared to other cities, indicating that symmetric local government environmental regulations and environmental collaborative governance contribute to restraining pollution transfer.
    Keywords intergovernmental competition ; pollution transfer ; environmental regulation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 333 ; 320
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: A novel enrofloxacin-degrading fungus, Humicola sp. KC0924g, isolated from the rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.

    Chen, Xueting / Zhang, Yuping / Liu, Jinghua

    International microbiology : the official journal of the Spanish Society for Microbiology

    2024  

    Abstract: A novel enrofloxacin-degrading fungus was isolated from a rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.. The isolate, designated KC0924g, was identified as a member of the genus Humicola based on morphological characteristics ... ...

    Abstract A novel enrofloxacin-degrading fungus was isolated from a rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.. The isolate, designated KC0924g, was identified as a member of the genus Humicola based on morphological characteristics and tandem conserved sequence analysis. The optimal temperature and pH for enrofloxacin degradation by strain KC0924g were 28 °C and 9.0, respectively. Under such condition, 98.2% of enrofloxacin with an initial concentration of 1 mg L
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1454951-7
    ISSN 1618-1905 ; 1139-6709
    ISSN (online) 1618-1905
    ISSN 1139-6709
    DOI 10.1007/s10123-024-00513-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The anti-tumor effect of silybin.

    Guo, Zhenli / Li, An / Song, Musheng / Zhang, Gai / Zhong, Jinghua

    Minerva medica

    2023  

    Language English
    Publishing date 2023-10-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.23.08741-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Huamoxiang 3, a variety bred for steaming and cooking type of whole grain black rice.

    Zhang, Qinglu / Zhang, Qifa / Xiao, Jinghua / Chen, Hao / Li, Yanhua / Yu, Sibin / He, Yuqing

    Molecular breeding : new strategies in plant improvement

    2024  Volume 44, Issue 4, Page(s) 31

    Language English
    Publishing date 2024-04-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1230924-2
    ISSN 1572-9788 ; 1380-3743
    ISSN (online) 1572-9788
    ISSN 1380-3743
    DOI 10.1007/s11032-024-01469-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Chemical proteomics approaches for protein post-translational modification studies.

    Zhang, Nan / Wu, Jinghua / Zheng, Qingfei

    Biochimica et biophysica acta. Proteins and proteomics

    2024  Volume 1872, Issue 4, Page(s) 141017

    Abstract: The diversity and dynamics of proteins play essential roles in maintaining the basic constructions and functions of cells. The abundance of functional proteins is regulated by the transcription and translation processes, while the alternative splicing ... ...

    Abstract The diversity and dynamics of proteins play essential roles in maintaining the basic constructions and functions of cells. The abundance of functional proteins is regulated by the transcription and translation processes, while the alternative splicing enables the same gene to generate distinct protein isoforms of different lengths. Beyond the transcriptional and translational regulations, post-translational modifications (PTMs) are able to further expand the diversity and functional scope of proteins. PTMs have been shown to make significant changes in the surface charges, structures, activation states, and interactome of proteins. Due to the functional complexity, highly dynamic nature, and low presence percentage, the study of protein PTMs remains challenging. Here we summarize and discuss the major chemical biology tools and chemical proteomics approaches to enrich and investigate the protein PTM of interest.
    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2918798-9
    ISSN 1878-1454 ; 1570-9639
    ISSN (online) 1878-1454
    ISSN 1570-9639
    DOI 10.1016/j.bbapap.2024.141017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Retraction Note: Ketamine exerts neurotoxic effects on the offspring of pregnant rats via the Wnt/β-catenin pathway.

    Zhang, Xintong / Zhao, Jinghua / Chang, Tian / Wang, Qi / Liu, Wenhan / Gao, Li

    Environmental science and pollution research international

    2024  Volume 31, Issue 15, Page(s) 23305

    Language English
    Publishing date 2024-03-05
    Publishing country Germany
    Document type Retraction of Publication
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32774-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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