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  1. Article ; Online: The Coming of a New Age: The Journal of Thoracic Oncology Goes Electronic in 2024.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 10, Page(s) 1257

    MeSH term(s) Humans ; Lung Neoplasms ; Medical Oncology ; Electronics
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tackling the High Cost of Oncology Drugs.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2021  Volume 16, Issue 11, Page(s) 1774–1777

    MeSH term(s) Antineoplastic Agents/therapeutic use ; Humans ; Lung Neoplasms/drug therapy ; Medical Oncology ; Pharmaceutical Preparations
    Chemical Substances Antineoplastic Agents ; Pharmaceutical Preparations
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2021.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Controversies in Thoracic Oncology.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2021  Volume 16, Issue 3, Page(s) 366–367

    MeSH term(s) Humans ; Lung Neoplasms ; Medical Oncology ; Thoracic Neoplasms/therapy
    Language English
    Publishing date 2021-02-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2021.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Expanding the KRASG12C Inhibitor Class: What Do We Need Next?

    Norman, Aurora / Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 7, Page(s) 844–846

    MeSH term(s) Humans ; Lung Neoplasms/drug therapy ; Enzyme Inhibitors/pharmacology
    Chemical Substances Enzyme Inhibitors
    Language English
    Publishing date 2023-12-26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation.

    Chattopadhyay, Sudipta / Adjei, Felicia / Kardos, Attila

    Journal of cardiovascular translational research

    2024  

    Abstract: Cardiac electrical biomarker (CEB), an indicator of ischaemia-induced change in myocyte polarity, has been proposed for diagnosis of acute coronary syndrome. However, effect of coronary occlusion on CEB has not been demonstrated. CEB was acquired before ( ...

    Abstract Cardiac electrical biomarker (CEB), an indicator of ischaemia-induced change in myocyte polarity, has been proposed for diagnosis of acute coronary syndrome. However, effect of coronary occlusion on CEB has not been demonstrated. CEB was acquired before (CEB0), during maximal adenosine hyperaemia (CEBhyp), balloon inflations (CEBmax) and 1 (CEB1h), 2 (CEB2h) and 3 (CEB3h) h after percutaneous coronary intervention along with pre- and post-procedural troponin-I. CEB of subjects with non-cardiac chest pain without risk factors was used as controls (CEBc). "Late recovery" (LR) of CEB was defined as CEB3h > median-CEB0. CEB was recorded in 75 patients undergoing stenting (group 1) including 8 with FFR < 0.8 (group 1a), 25 with FFR ≥ 0.8 (group 2) and 49 controls. In group 1, CEB0 (median, IQR) was higher than CEBc (48.0; 29.5-88.3 vs 30.0; 17.0-44.0; p < 0.001). CEBmax (185; 105.0-331.0) was higher than CEB0 (p < 0.0001). CEB1h (78.0; 31.5-143.8; p < 0.0001) and CEB2h (63.0; 31.5-114.3; p = 0.039) were higher than CEB0 while CEB3h (54.0; 24.3-94.8, p = 0.152) was similar. LR occurred in 50.7% patients. CEBmax predicted LR (OR 1.01, 95% CI 1.00-1.01, p < 0.001) (AUC 0.759, p < 0.001). CEB0 in group 1a and group 2 were similar (p = 0.524). CEBhyp was higher than CEB0 in group 1a (126.0, 109.5-266.0 vs 47.5, 20.5-73.5; p = 0.016) and group 2 (44.0, 27.8-104.8 vs 39.0, 24.0-90.3; p = 0.014). CEBhyp was higher in group 1a than 2 (p = 0.039). CEBhyp (AUC 0.75, p = 0.017) accurately predicted FFR < 0.8. Coronary arterial occlusion increases CEB that retains a "memory" of the ischaemic event. CEBhyp was higher only when FFR was ischaemic and accurately identified FFR < 0.8.
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2422411-X
    ISSN 1937-5395 ; 1937-5387
    ISSN (online) 1937-5395
    ISSN 1937-5387
    DOI 10.1007/s12265-024-10487-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: JTO Clinical and Research Reports Is Born.

    Adjei, Alex A

    JTO clinical and research reports

    2020  Volume 1, Issue 1, Page(s) 100014

    Language English
    Publishing date 2020-03-30
    Publishing country United States
    Document type Editorial
    ISSN 2666-3643
    ISSN (online) 2666-3643
    DOI 10.1016/j.jtocrr.2020.100014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A Call to Arms: Reducing Disparities in Lung Cancer Care Worldwide.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2020  Volume 15, Issue 11, Page(s) 1700–1702

    MeSH term(s) Ethnic Groups ; Healthcare Disparities ; Humans ; Lung Neoplasms/epidemiology ; Lung Neoplasms/therapy ; United States
    Language English
    Publishing date 2020-10-23
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2020.09.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An Oxidation Study of Phthalimide-Derived Hydroxylactams.

    Adjei, Bernard L / Luzzio, Frederick A

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 2

    Abstract: A systematic study of the oxidation of 3-hydroxy-2-substituted isoindolin-1-ones (hydroxylactams) and their conversion to the corresponding phthalimides was undertaken using three oxidants. Of special interest was the introduction of nickel peroxide ( ... ...

    Abstract A systematic study of the oxidation of 3-hydroxy-2-substituted isoindolin-1-ones (hydroxylactams) and their conversion to the corresponding phthalimides was undertaken using three oxidants. Of special interest was the introduction of nickel peroxide (NiO
    Language English
    Publishing date 2022-01-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27020548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Lung Cancer Worldwide.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2019  Volume 14, Issue 6, Page(s) 956

    MeSH term(s) Humans ; Lung Neoplasms ; Pulmonary Artery ; Saudi Arabia ; Smoking
    Language English
    Publishing date 2019-05-23
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2019.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Progress in the Diagnosis and Treatment of Thoracic Malignancies Continues Unabated.

    Adjei, Alex A

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2019  Volume 14, Issue 5, Page(s) 757

    MeSH term(s) Humans ; Lung Neoplasms/complications ; Lung Neoplasms/pathology ; Thoracic Neoplasms/diagnosis ; Thoracic Neoplasms/pathology ; Thoracic Neoplasms/secondary
    Language English
    Publishing date 2019-04-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2019.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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