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  1. Article ; Online: Reply to Chang et al.

    Su, Chia-Ping / Chan, K Arnold / Huang, Ching-Tai / Fang, Chi-Tai

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2022  Volume 75, Issue 9, Page(s) 1677

    Language English
    Publishing date 2022-06-15
    Publishing country United States
    Document type Letter
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciac464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correction: Chang et al. Decursinol Angelate Arrest Melanoma Cell Proliferation by Initiating Cell Death and Tumor Shrinkage via Induction of Apoptosis.

    Chang, Sukkum Ngullie / Khan, Imran / Kim, Chang Geon / Park, Seon Min / Choi, Dong Kyu / Lee, Heejin / Hwang, Buyng Su / Kang, Sun Chul / Park, Jae Gyu

    International journal of molecular sciences

    2022  Volume 23, Issue 3

    Abstract: The author wishes to make the following correction to this paper [ ... ]. ...

    Abstract The author wishes to make the following correction to this paper [...].
    Language English
    Publishing date 2022-01-31
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23031629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Combination of Individual Herb of Mi-Jian-Chang-Pu Formula Exerts a Synergistic Effect in the Treatment of Ischemic Stroke in Rats.

    Lu, Fangfang / Su, Xiaojuan / Liu, Jingjing / Zong, Rong / Ding, Shuqin / Yang, Lingling / Liu, Jing / Wilson, Gidion / Li, Liuyan / Yang, Youyue / Wang, Xiaoying / Wang, Weibiao / Ma, Xueqin

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 9365760

    Abstract: Mi-Jian-Chang-Pu formula (MJCPF), composed of ...

    Abstract Mi-Jian-Chang-Pu formula (MJCPF), composed of
    MeSH term(s) Animals ; Male ; Rats ; Brain Ischemia/drug therapy ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/metabolism ; Ischemic Stroke ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Rats, Sprague-Dawley ; Stroke/drug therapy
    Chemical Substances asarone ; crocin (877GWI46C2) ; Neuroprotective Agents
    Language English
    Publishing date 2022-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/9365760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: In-Situ Radar Observation of Shallow Lunar Regolith at the Chang’E-5 Landing Site

    Feiyang Fang / Chunyu Ding / Jianqing Feng / Yan Su / Ravi Sharma / Iraklis Giannakis

    Remote Sensing, Vol 15, Iss 21, p

    Research Progress and Perspectives

    2023  Volume 5173

    Abstract: China accomplished a historic milestone in 2020 when the mission Chang’e-5 (CE-5) to the Lunar’s ...

    Abstract China accomplished a historic milestone in 2020 when the mission Chang’e-5 (CE-5) to the Lunar’s surface was successfully launched. An extraordinary component of this mission is the “Lunar Regolith Penetrating Radar” (LRPR) housed within its lander, which currently stands as the most advanced payload in terms of vertical resolution among all penetrating radars employed in lunar exploration. This provides an unprecedented opportunity for high-precision research into the interior structure of the shallow lunar regolith. Previous studies have achieved fruitful research results based on the data from LRPR, updating our perception of the shallow-level regolith of the Moon. This paper provides an overview of the new advancements achieved by the LRPR in observing the basic structure of the shallow regolith of the Moon. It places special emphasis on the role played by the LRPR in revealing details about the shallow lunar regolith’s structure, its estimated dielectric properties, the provenance of the regolith materials from the landing area, and its interpretation of the geological stratification at the landing site. Lastly, it envisions the application and developmental trends of in situ radar technology in future lunar exploration.
    Keywords CE-5 mission ; lunar regolith ; dielectric properties ; lunar radar detection ; the Moon ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Potential Therapeutic Effects of Mi-Jian-Chang-Pu Decoction on Neurochemical and Metabolic Changes of Cerebral Ischemia-Reperfusion Injury in Rats.

    Liu, Jingjing / Yang, Lingling / Niu, Yang / Su, Chao / Wang, Yingli / Ren, Ruru / Chen, Jianyu / Ma, Xueqin

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 7319563

    Abstract: As a traditional Chinese medicine formula, Mi-Jian-Chang-Pu decoction (MJCPD) has been successfully ... the changes of GSH, GSSG, GSH-PX, GSSG/GSH, LDH, L-LA, IL-6, TNF- ...

    Abstract As a traditional Chinese medicine formula, Mi-Jian-Chang-Pu decoction (MJCPD) has been successfully used in patients with language dysfunction and hemiplegia after ischemic stroke (IS). Given the excellent protective effects of MJCPD against nerve damage caused by IS in clinical settings, the present investigation mainly focused on its underlying mechanism on ischemia-reperfusion (IR) injury. Firstly, by applying the MCAO-induced cerebral IR injury rats, the efficacy of MJCPD on IS was estimated using the neurological deficit score, TTC, HE, and IHC staining, and neurochemical measurements. Secondly, an UHPLC-QTOF-MS/MS-based nontargeted metabolomics was developed to elucidate the characteristic metabolites. MJCPD groups showed significant improvements in the neurological score, infarction volume, and histomorphology, and the changes of GSH, GSSG, GSH-PX, GSSG/GSH, LDH, L-LA, IL-6, TNF-
    MeSH term(s) Animals ; Brain Ischemia/drug therapy ; Glutathione Disulfide ; Humans ; Ischemic Stroke ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/drug therapy ; Reperfusion Injury/metabolism ; Tandem Mass Spectrometry
    Chemical Substances Glutathione Disulfide (ULW86O013H)
    Language English
    Publishing date 2022-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/7319563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Lunar Regolith Structure and Electromagnetic Properties of Chang’E-5 Landing Site

    Li, Yuxi / Zhou, Bin / Shen, Shaoxiang / Lu, Wei / Tang, Chuanjun / Li, Shidong / Su, Yan / Dai, Shun / Fang, Guangyou

    Remote Sensing. 2022 Sept. 11, v. 14, no. 18

    2022  

    Abstract: On 1 December 2020, China’s Chang’E-5 (CE-5) probe successfully landed in the northeastern Oceanus ...

    Abstract On 1 December 2020, China’s Chang’E-5 (CE-5) probe successfully landed in the northeastern Oceanus Procellarum. This work mainly presents the results of Lunar Regolith Penetrating Radar (LRPR) equipped on the CE-5 Lander. The lunar regolith structure of the landing site from the surface to 3-m depth is unveiled by LRPR, which found that abundant rock fragments are distributed in uniform lunar regolith. The imaging result proved that the drilling and sampling process was prevented by big rocks at about 100 cm depth. On the basis of the response of lunar soil to electromagnetic (EM) wave, the EM properties of the landing site estimate that the relative dielectric constant and the loss tangent are 2.520 ± 0.186 and 0.0133 ± 0.0020, respectively.
    Keywords dielectric properties ; radar ; regolith ; soil ; China
    Language English
    Dates of publication 2022-0911
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2513863-7
    ISSN 2072-4292
    ISSN 2072-4292
    DOI 10.3390/rs14184539
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Evidence of water on the lunar surface from Chang’E-5 in-situ spectra and returned samples

    Jianjun Liu / Bin Liu / Xin Ren / Chunlai Li / Rong Shu / Lin Guo / Songzheng Yu / Qin Zhou / Dawei Liu / Xingguo Zeng / Xingye Gao / Guangliang Zhang / Wei Yan / Hongbo Zhang / Lihui Jia / Shifeng Jin / Chunhua Xu / Xiangjin Deng / Jianfeng Xie /
    Jianfeng Yang / Changning Huang / Wei Zuo / Yan Su / Weibin Wen / Ziyuan Ouyang

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 10

    Abstract: Laboratory analysis of returned Chang’E-5 samples from the lunar surface show their hydroxyl ...

    Abstract Laboratory analysis of returned Chang’E-5 samples from the lunar surface show their hydroxyl contents to be on the weak end of lunar hydration features.
    Keywords Science ; Q
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Pleiocarpumlignan A, a new dineolignan from Piper pleiocarpum Chang ex Tseng

    Xu, Wen-Hui / Su, Xiao-Min / Zhang, Xin-Min / Qi, JianHua / Wang, Dawei / Wang, Meng / Liang, Qian

    Natural product research. 2020 Oct. 1, v. 34, no. 19

    2020  

    Abstract: The investigation of chemical constituents from the whole plants Piper pleiocarpum Chang ex Tseng ... isolated from Piper pleiocarpum Chang ex Tseng. The ¹³C NMR spectra of 2 were completely assigned ...

    Abstract The investigation of chemical constituents from the whole plants Piper pleiocarpum Chang ex Tseng resulted in the isolation of one new dineolignan, pleiocarpumlignan A (1), along with one known benzoate derivative, trans-2,3-diacetoxy-1-[(benzoy1oxy)methyl]-cyclohexa-4,6-diene (2), and two known neolignans (3–4) as (±)-trans-dehydrodiisoeugenol (3), (7R,8R,3′S)-△⁸′-3′,6′-dihydro-3′-methoxy-3,4-methylenedioxy-6′-oxo-8,3′,7,O,4′-lignan (4). Their structures were elucidated through extensive spectroscopic analyses including 1D, 2D NMR, HR-ESI-MS, and by comparison with the literature. All compounds (1–4) were firstly isolated from Piper pleiocarpum Chang ex Tseng. The ¹³C NMR spectra of 2 were completely assigned for the first time. Cytotoxic activities of these isolated compounds against five human cancer cell lines (including A-549, SMMC-7721, HL-60, MCF-7, and SW-480) were evaluated.
    Keywords Piper ; cell lines ; chemical composition ; cytotoxicity ; humans ; lignans ; literature ; neoplasm cells ; research ; spectral analysis
    Language English
    Dates of publication 2020-1001
    Size p. 2809-2815.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-light
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2019.1593167
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: A potential subsurface cavity in the continuous ejecta deposits of the Ziwei crater discovered by the Chang’E-3 mission

    Chunyu Ding / Zhiyong Xiao / Yan Su

    Earth, Planets and Space, Vol 73, Iss 1, Pp 1-

    2021  Volume 12

    Abstract: Abstract In the radargram obtained by the high-frequency lunar penetrating radar onboard the Chang ...

    Abstract Abstract In the radargram obtained by the high-frequency lunar penetrating radar onboard the Chang’E-3 mission, we notice a potential subsurface cavity that has a smaller permittivity compared to the surrounding materials. The two-way travel time between the top and bottom boundaries of the potential cavity is ~ 21 ns, and the entire zone is located within the continuous ejecta deposits of the Ziwei crater, which generally have similar physical properties to typical lunar regolith. We carried out numerical simulations for electromagnetic wave propagation to investigate the nature of this low-permittivity zone. Assuming different shapes for this zone, a comprehensive comparison between our model results and the observed radargram suggests that the roof of this zone is convex and slightly inclined to the south. Modeling subsurface materials with different relative permittivities suggests that the low-permittivity zone is most likely formed due to a subsurface cavity. The maximum vertical dimension of this potential cavity is ~ 3.1 m. While the continuous ejecta deposits of Ziwei crater are largely composed of pre-impact regolith, competent mare basalts were also excavated, which is evident by the abundant meter-scale boulders on the wall and rim of Ziwei crater. We infer that the subsurface cavity is supported by excavated large boulders, which were stacked during the energetic emplacement of the continuous ejecta deposits. However, the exact geometry of this cavity (e.g., the width) cannot be constrained using the single two-dimensional radar profile. This discovery indicates that large voids formed during the emplacement of impact ejecta should be abundant on the Moon, which contributes to the high bulk porosity of the lunar shallow crust, as discovered by the GRAIL mission. Our results further suggest that ground penetrating radar is capable of detecting and deciphering subsurface cavities such as lava tubes, which can be applied in future lunar and deep space explorations. Subsurface cavities of the Moon are ...
    Keywords Chang’E-3 ; Lunar penetrating radar ; Moon ; Impact crater ; Porosity ; Geography. Anthropology. Recreation ; G ; Geodesy ; QB275-343 ; Geology ; QE1-996.5
    Subject code 550
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A Novel Approach for Permittivity Estimation of Lunar Regolith Using the Lunar Penetrating Radar Onboard Chang’E-4 Rover

    Ruigang Wang / Yan Su / Chunyu Ding / Shun Dai / Chendi Liu / Zongyu Zhang / Tiansheng Hong / Qing Zhang / Chunlai Li

    Remote Sensing, Vol 13, Iss 3679, p

    2021  Volume 3679

    Abstract: ... 14%, and 9%, respectively. The thickness of the lunar regolith at the Chang’E 4 landing site is ...

    Abstract Accurate relative permittivity is essential to the further analysis of lunar regolith. The traditional hyperbola fitting method for the relative permittivity estimation using the lunar penetrating radar generally ignored the effect of the position and geometry of antennas. This paper proposed a new approach considering the antenna mounting height and spacing in more detail. The proposed method is verified by numerical simulations of the regolith models. Hence the relative permittivity of the lunar regolith is calculated using the latest high-frequency radar image obtained by the Yutu-2 rover within the first 24 lunar days. The simulation results show that the relative permittivity is underestimated when derived by the traditional method, especially at the shallow depth. The proposed method has improved the accuracy of the estimated lunar regolith relative permittivity at a depth of 0–3 m, 3–6 m, and 6–10 m by 35%, 14%, and 9%, respectively. The thickness of the lunar regolith at the Chang’E 4 landing site is reappraised to be 11.1 m, which improved by ~8% compared with previous studies.
    Keywords moon ; Chang’E 4 mission ; relative permittivity ; lunar regolith ; lunar penetrating radar ; Science ; Q
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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