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  1. Article ; Online: Areca nut and oral cancer.

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Oral diseases

    2024  

    Abstract: Introduction: The association between areca nut consumption and oral cancer has been a subject of increasing concern in global public health.: Global perspective: Areca nut, often chewed in various forms such as betel quid, is deeply rooted in ... ...

    Abstract Introduction: The association between areca nut consumption and oral cancer has been a subject of increasing concern in global public health.
    Global perspective: Areca nut, often chewed in various forms such as betel quid, is deeply rooted in cultural practices across Asia and other parts of the world. Epidemiological studies consistently reveal a significant correlation between areca nut use and the incidence of oral cancer, emphasizing the need for targeted preventive measures. The complex interplay of areca nut's bioactive compounds, particularly arecoline, with cellular processes, contributes to the initiation and progression of oral carcinogenesis. Mechanistic insights into the genotoxic and cytotoxic effects of its components underscore the urgency for comprehensive public health interventions.
    Public health: Efforts to address this public health challenge involve multidisciplinary approaches, encompassing education, policy implementation, and behavioral interventions. Understanding the socio-cultural factors influencing areca nut consumption is pivotal for designing effective awareness campaigns and cessation programs.
    Conclusion: As oral cancer remains a significant global health burden, unraveling the nuanced relationship between areca nut and its role in oral carcinogenesis is crucial for advancing preventive strategies and mitigating the impact of this modifiable risk factor.
    Language English
    Publishing date 2024-04-02
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14943
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    Zs.A 4427: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Clinical trials during COVID ‐19

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Head & Neck

    2020  Volume 42, Issue 7, Page(s) 1516–1518

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 1043-3074
    DOI 10.1002/hed.26223
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Tobacco use and vaping in the COVID-19 era.

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Head & neck

    2020  Volume 42, Issue 6, Page(s) 1240–1242

    Abstract: Health crises have become a popular topic of discussion. In the wave of the ongoing pandemic, experts have suggested the role of vaping and other tobacco product use exemplifying the vulnerability of the population to contract the COVID-19. We discuss ... ...

    Abstract Health crises have become a popular topic of discussion. In the wave of the ongoing pandemic, experts have suggested the role of vaping and other tobacco product use exemplifying the vulnerability of the population to contract the COVID-19. We discuss some of the events that led up to these conclusions and also offer a unique insight into another form of tobacco use that is potentially propagating its spread especially in the South Asian region-chewed tobacco. Both of these have been a perennial issue that head and neck cancer surgeons have been dealing with. Governments and head and neck cancer care providers now have an opportunity to deal with a common enemy in the midst of this pandemic.
    MeSH term(s) Asia ; COVID-19 ; Communicable Disease Control/methods ; Coronavirus Infections/prevention & control ; Female ; Global Health ; Head and Neck Neoplasms/diagnosis ; Head and Neck Neoplasms/epidemiology ; Humans ; Male ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Pneumonia, Viral/prevention & control ; Risk Assessment ; Smoking/adverse effects ; Smoking/epidemiology ; Tobacco Use/epidemiology ; Vaping/adverse effects ; Vaping/epidemiology ; Vulnerable Populations/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.26208
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    Zs.A 1493: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Clinical trials during COVID-19.

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Head & neck

    2020  Volume 42, Issue 7, Page(s) 1516–1518

    Abstract: As this ever-evolving pandemic lays itself, more of its impact is being understood. Until recently, most guidelines were reported to aid in managing and treating suspected or confirmed cases. Research institutions around the world are responding with a ... ...

    Abstract As this ever-evolving pandemic lays itself, more of its impact is being understood. Until recently, most guidelines were reported to aid in managing and treating suspected or confirmed cases. Research institutions around the world are responding with a sense of confusion. Some are continuing routinely, especially those who are overseeing clinical trials that could offer life-saving therapies, particularly against the novel coronavirus. Since research must continue even in the face of a shutdown, we aim to collate the currently available recommendations from various organizations and provide guidance to head and neck researchers across the world during these trying times.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Clinical Trials as Topic/organization & administration ; Coronavirus Infections/epidemiology ; Data Management ; Ethics Committees, Research ; Humans ; Informed Consent ; Occupational Health ; Pandemics ; Patient Safety ; Pneumonia, Viral/epidemiology ; Quarantine ; Risk Assessment ; SARS-CoV-2 ; Self Administration ; Telecommunications
    Keywords covid19
    Language English
    Publishing date 2020-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.26223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1493: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Tobacco use and vaping in the COVID ‐19 era

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Head & Neck

    2020  Volume 42, Issue 6, Page(s) 1240–1242

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 1043-3074
    DOI 10.1002/hed.26208
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Misleading Evidence of Electronic Cigarettes Efficacy for Tobacco Cessation

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Indian Journal of Medical and Paediatric Oncology

    2020  Volume 41, Issue 03, Page(s) 319–320

    Language English
    Publishing date 2020-05-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0971-5851 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0971-5851 ; 0975-2129
    DOI 10.4103/ijmpo.ijmpo_89_20
    Database Thieme publisher's database

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  7. Article ; Online: Incidence and impact of skip metastasis in the neck in early oral cancer: Reality or a myth?

    Gurmeet Singh, Arjun / Sathe, Pranav / Roy, Satadru / Thiagrajan, Shivakumar / Chaukar, Devendra / Chaturvedi, Pankaj

    Oral oncology

    2022  Volume 135, Page(s) 106201

    Abstract: Objectives: Varying evidence exists surrounding skip metastasis in clinically node-negative oral cancer. We aim to report its incidence, identify factors predicting its presence, and determine survival outcomes to possibly decide "adequacy" of neck ... ...

    Abstract Objectives: Varying evidence exists surrounding skip metastasis in clinically node-negative oral cancer. We aim to report its incidence, identify factors predicting its presence, and determine survival outcomes to possibly decide "adequacy" of neck dissection for this select group.
    Methods: A review of audit records (clinical and pathologic) was undertaken to identify early stage (cT1/T2 cN0) oral squamous carcinoma patients operated between January 2016 and December 2020. Skip metastasis was defined as presence of nodal metastases distant from the primary tumour and at a lower level without metastases at levels above this. The factors predicting its presence were determined using chi-square and multivariate tests. Survival analysis was performed using Kaplan-Meier and regression hazard models.
    Results: Occult metastasis rate was 17.9 % among 761 patients, with 47.1 % travelling to level I. Skip metastasis at level III was seen in 1.2 % and level IV was 0.3 %. Presence of PNI predicted the presence of skip metastasis at level III (p = 0.041, OR-0.241, 95 %CI 0.062-0.942) and no significant factors were identified for level IV. The 5-year disease-free survival was significantly reduced with isolated level IV metastasis (50 % vs 79.6 %, p = 0.017). Isolated occult metastasis at level Ia was in 0.3 %, all from tongue cancers. Their presence did not impact the 5-year overall survival (100 % vs 90.7 %, p = 0.628) and disease-specific survival (100 % vs 92.5 %, p = 0.675).
    Conclusion: The negligible incidence of skip metastasis to level IV in a clinically node negative neck suggests that clearance up to level III might be adequate in a large majority of patients.
    MeSH term(s) Humans ; Lymphatic Metastasis/pathology ; Incidence ; Lymph Nodes/pathology ; Neoplasm Staging ; Retrospective Studies ; Mouth Neoplasms/pathology ; Neck Dissection
    Language English
    Publishing date 2022-10-12
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2022.106201
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    Zs.A 4869: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article: Clinical trials during COVID-19

    Singh, Arjun Gurmeet / Chaturvedi, Pankaj

    Head Neck

    Abstract: As this ever-evolving pandemic lays itself, more of its impact is being understood. Until recently, most guidelines were reported to aid in managing and treating suspected or confirmed cases. Research institutions around the world are responding with a ... ...

    Abstract As this ever-evolving pandemic lays itself, more of its impact is being understood. Until recently, most guidelines were reported to aid in managing and treating suspected or confirmed cases. Research institutions around the world are responding with a sense of confusion. Some are continuing routinely, especially those who are overseeing clinical trials that could offer life-saving therapies, particularly against the novel coronavirus. Since research must continue even in the face of a shutdown, we aim to collate the currently available recommendations from various organizations and provide guidance to head and neck researchers across the world during these trying times.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #141730
    Database COVID19

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  9. Article ; Online: SMOKING AND OTHER ADDICTIONS RELATED TO CANCER OF THE HEAD AND NECK

    Arjun Gurmeet Singh / Pankaj Chaturvedi

    Revista Médica Clínica Las Condes, Vol 29, Iss 4, Pp 405-

    2018  Volume 410

    Abstract: Head and neck canceris a major health problem globally with the projected incidence of 1,176,149 cases, an approximate 20% increase, in 2020. Most research today is directed towards reducing this incidence by understanding the mechanism and etiologic ... ...

    Abstract Head and neck canceris a major health problem globally with the projected incidence of 1,176,149 cases, an approximate 20% increase, in 2020. Most research today is directed towards reducing this incidence by understanding the mechanism and etiologic factors associated. Majority of these factors are habitual, with tobacco use being the most common. There are many variations in the use of tobacco ranging from smoked to smokeless, as well as novel innovations like e-cigarette and tobacco tablets, being introduced today. There are also many studies suggesting tobacco use as a gateway drug to other habitual substances, including alcohol and marijuana use. Many of these substances are now being utilized more by the youth than adults, which might develop a shift in the age of incidence in the future. Few countries have asignificant population of immigrants, who bring with thema diverse range of traditional habits, the effects of which still have to be studied on the population. An overview of the various habitual etiologiesassociated with head and neck cancers, and their mechanism of action have been reviewed here so as to get a holistic idea of these substances. Resumen: El cáncer de cabeza y cuello es un problema de salud relevante en el mundo, con una incidencia proyectada de 1176149 casos, un aumento aproximado del 20%, en 2020. La mayoría de las investigaciones actuales apuntan a reducir esta incidencia con la comprensión de los mecanismo de su génesis y los factores etiológicos asociados. La mayoría de estos factores son adicciones, siendo el uso del tabaco el más común. Hay muchas variaciones en el uso del tabaco que van desde con o sin combustión, así como novedosas innovaciones como el cigarrillo electrónico y las tabletas de tabaco, que se están introduciendo hoy en día. También hay muchos estudios que sugieren el uso del tabaco como una droga de entrada al uso de otras sustancias adictivas, incluido el consumo de alcohol y marihuana. Muchas de estas sustancias ahora están siendo utilizadas más por los ...
    Keywords Medicine ; R
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Navigating the impact of COVID ‐19 on palliative care for head and neck cancer

    Singh, Arjun Gurmeet / Deodhar, Jayita / Chaturvedi, Pankaj

    Head & Neck

    2020  Volume 42, Issue 6, Page(s) 1144–1146

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 1043-3074
    DOI 10.1002/hed.26211
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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