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Article: Seroprevalence of Human T-cell Lymphotropic Virus Types I/II Among Blood Donors in a Tertiary Hospital in Oman.

Al-Bulushi, Noora / Al Maamari, Khuloud / Alawi, Fatma Ba / Al-Riyami, Arwa Z / Al Marhoobi, Ali

2024 Volume 39, Issue 1, Page(s) e587

Abstract: Objectives: Routine blood donor screening of human T-cell lymphotropic virus (HTLV) has been practiced in Oman since 2017. Limited data exists on HTLV seroprevalence among Omanis. This study aims to determine the seroprevalence of HTLV-I/II among blood ... ...

Abstract	Objectives: Routine blood donor screening of human T-cell lymphotropic virus (HTLV) has been practiced in Oman since 2017. Limited data exists on HTLV seroprevalence among Omanis. This study aims to determine the seroprevalence of HTLV-I/II among blood donors attending a hospital-based blood bank to assess the need for a universal versus targeted screening. Methods: We conducted a retrospective review of blood donors' results attending a hospital blood bank between January 2017 and February 2020. Blood samples were screened for HTLV-I/II antibodies using ARCHITECT i2000SR. Reactive samples underwent further testing by immunoblot assay (MP Diagnostics HTLV Blot 2.4). Age, gender, and nationality were assessed. All components manufactured at the blood bank undergo leukoreduction before storage. Results: A total of 24 469 first-time blood donors were screened for HTLV antibodies. Most participants were male (n = 22 186, 90.7%), and the majority were Omani (n = 22 711, 92.8%). The age range was 18 to 64 years, with a median of 32 years. The seroreactivity rate was 0.2% (43; 95% CI: 0.12-0.23). Confirmatory testing by immunoblot revealed three indeterminate results (7.9%), of which two were Omani and one non-Omani donor, and the remaining 40 seroreactive donors tested negative. Conclusions: Our study revealed zero seroprevalence of confirmed HTLV among blood donors. The continuation of universal screening for first-time donors is a standard of care. With universal leukoreduction at Sultan Qaboos University Hospital and a very low risk of HTLV in Oman's population, the need for screening regular donors can be reconsidered if these findings are confirmed on a larger scale involving other blood banks in Oman.
Language	English
Publishing date	2024-01-31
Publishing country	Oman
Document type	Journal Article
ZDB-ID	2571431-4
ISSN	2070-5204 ; 1999-768X
ISSN (online)	2070-5204
ISSN	1999-768X
DOI	10.5001/omj.2024.42
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: E-learning in transfusion medicine: A scoping review.

Al-Riyami, Arwa Z / Vanden Broeck, Jana / Rahimi-Levene, Naomi / Das, Soumya / Saxon, Ben / Lin, Yulia / Stanworth, Simon J

Transfusion

2023 Volume 63, Issue 12, Page(s) 2362–2376

MeSH term(s)	Humans ; Transfusion Medicine/education ; Computer-Assisted Instruction ; Learning
Language	English
Publishing date	2023-10-24
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.17564
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Article: The ISBT e-learning module in transfusion reaction: An initiative for a global outreach.

Wasiluk, Tomasz / So-Osman, Cynthia / van den Burg, Peter / Herczenik, Eszter / Al-Riyami, Arwa Z

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2022 Volume 62, Issue 1, Page(s) 103633

MeSH term(s)	Humans ; Computer-Assisted Instruction ; Blood Transfusion ; Blood Banks
Language	English
Publishing date	2022-12-15
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2022.103633
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Zs.A 1739: Show issues

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Article: Preoperative Anemia is Associated with Increased Intraoperative Mortality in Patients Undergoing Cardiac Surgery.

Al-Riyami, Arwa Z / Baskaran, Balan / Panchatcharam, Sathiya M / Al-Sabti, Hilal

Oman medical journal

2021 Volume 36, Issue 3, Page(s) e267

Abstract: Objectives: We sought to investigate the incidence of preoperative anemia in cardiac surgery and its association with outcomes.: Methods: A retrospective review of clinical, laboratory, and transfusion data for all patients who underwent cardiac ... ...

Abstract	Objectives: We sought to investigate the incidence of preoperative anemia in cardiac surgery and its association with outcomes. Methods: A retrospective review of clinical, laboratory, and transfusion data for all patients who underwent cardiac surgery at Sultan Qaboos University Hospital between 2008 and 2014 was performed. Patients were divided into two groups, anemic and non-anemic, with anemia defined as hemoglobin levels < 13 g/dL (males) and < 12 g/dL (females). Clinical variables were compared using chi-square and independent Results: A total of 599 patients (69.9% males and 30.1% females) were included in the study; 69.3% underwent coronary artery bypass surgery. Preoperative anemia was found in 76.1% of females and 26.7% of male patients. Rates of intraoperative red blood cell transfusions were higher among anemic patients (75.9% vs. 52.3%, Conclusions: Preoperative anemia in cardiac surgery is independently associated with increased intraoperative mortality and early readmission rates post-surgery.
Language	English
Publishing date	2021-05-31
Publishing country	Oman
Document type	Journal Article
ZDB-ID	2571431-4
ISSN	2070-5204 ; 1999-768X
ISSN (online)	2070-5204
ISSN	1999-768X
DOI	10.5001/omj.2021.66
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Article: Red cell alloimmunization in transfusion-dependent and transfusion-independent beta thalassemia: A review from the Eastern Mediterranean Region (EMRO).

Al-Riyami, Arwa Z / Daar, Shahina

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2019 Volume 58, Issue 6, Page(s) 102678

Abstract: Background: β-Thalassemia is considered one of the common hemoglobin disorders in the Arabian Peninsula. Red blood cell (RBC) transfusion is a crucial component of the management of transfusion-dependent β-Thalassemia patients. Patients with Thalassemia ...

Abstract	Background: β-Thalassemia is considered one of the common hemoglobin disorders in the Arabian Peninsula. Red blood cell (RBC) transfusion is a crucial component of the management of transfusion-dependent β-Thalassemia patients. Patients with Thalassemia Intermedia (TI), also known as non-transfusion dependent β-thalassemia, have a wide clinical presentation and variable transfusion dependence. Rates of RBC alloimmunization and its risk factors in transfusion-dependent β-thalassemia patients varied between different reports. Risk of alloimmunization is higher in TI patients. Material and methods: A literature review on existing reports on alloimmunization rates and risk factors in transfusion dependent and non-transfusion dependent β-thalassemia in the Eastern Mediterranean region was performed. Results: A total of 17 publications were found. Reported rates of alloimmunization among transfusion-dependent β-Thalassemia patients ranged between 2.87 and 30 % and between 6.8 and 19.5 % among TI patients. Most centers utilize ABO and RhD matched RBCs. The most common antibodies described are anti-K and anti-E. The risk factors described included age at onset of transfusion, gender, history of splenectomy, duration of transfusion and number of units transfused. Rate of autoantibody formation ranged between 0.1 and 45 %. Conclusion: Our review showed variable alloimmunization rates and risk factors in thalassemia patients and scant data on TI patients. The commonest antibodies are anti-K and anti-E. Further studies are required in addressing the rate of alloimmunization, cross-match requirements and role of genotyping in this group of patients. Transfusion support of patients with thalassemia necessitates the availability of blood bank facilities and specialized expertise.
MeSH term(s)	Blood Transfusion ; Erythrocytes/immunology ; Humans ; Immunization ; Mediterranean Region ; beta-Thalassemia/etiology
Language	English
Publishing date	2019-11-07
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2019.102678
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Zs.A 1739: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
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Article ; Online: Transfusion in Haemoglobinopathies: Review and recommendations for local blood banks and transfusion services in Oman.

Al-Riyami, Arwa Z / Daar, Shahina

Sultan Qaboos University medical journal

2018 Volume 18, Issue 1, Page(s) e3–e12

Abstract: Sickle cell disease and homozygous β-thalassaemia are common haemoglobinopathies in Oman, with many implications for local healthcare services. The transfusions of such patients take place in many hospitals throughout the country. Indications for blood ... ...

Abstract	Sickle cell disease and homozygous β-thalassaemia are common haemoglobinopathies in Oman, with many implications for local healthcare services. The transfusions of such patients take place in many hospitals throughout the country. Indications for blood transfusions require local recommendations and guidelines to ensure standardised levels of care. This article summarises existing transfusion guidelines for this group of patients and provides recommendations for blood banks and transfusion services in Oman. This information is especially pertinent to medical professionals and policy-makers developing required services for the standardised transfusion support of these patients.
MeSH term(s)	Anemia, Sickle Cell/therapy ; Blood Banks/standards ; Blood Transfusion/methods ; Hemoglobinopathies/complications ; Hemoglobinopathies/therapy ; Humans ; Oman ; Review Literature as Topic ; beta-Thalassemia/therapy
Language	English
Publishing date	2018-04-04
Publishing country	Oman
Document type	Journal Article ; Review
ZDB-ID	2650196-X
ISSN	2075-0528 ; 2075-0528
ISSN (online)	2075-0528
ISSN	2075-0528
DOI	10.18295/squmj.2018.18.01.002
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Article ; Online: COVID-19 and the impact on blood availability and transfusion practices in low- and middle-income countries.

Barnes, Linda S / Al-Riyami, Arwa Z / Ipe, Tina S / Bloch, Evan M / Sibinga, Cees Smit / Eichbaum, Quentin G

Transfusion

2022 Volume 62, Issue 2, Page(s) 336–345

Abstract: Background/case studies: The coronavirus disease 2019 (COVID-19) pandemic disrupted the global blood supply. Low- and middle-income countries (LMICs) already experienced blood supply deficits that preceded the pandemic. We sought to characterize the ... ...

Abstract	Background/case studies: The coronavirus disease 2019 (COVID-19) pandemic disrupted the global blood supply. Low- and middle-income countries (LMICs) already experienced blood supply deficits that preceded the pandemic. We sought to characterize the challenges experienced during the pandemic, and adaptations, such as COVID-19 convalescent plasma (CCP). Study design/methods: A cross-sectional survey explored blood availability, challenges, and adaptations. The survey contained 31 questions, e-mailed in English, French, or Spanish, to selected LMIC blood transfusion practitioners. Data acquisition occurred between October 28 and December 28, 2020. A mixed methods analysis followed. Results/findings: A total of 31 responses from 111 invitations represented 26 LMIC countries. Languages included English (22, 71%), Spanish (7, 22.6%), and French (2, 6.4%). Most respondents (29/31, 93.5%) collected blood; 58% also transfused blood (18/31). The supply of blood came from hospital-based blood donations (61%, 11/18); blood suppliers (17%, 3/18); and both sources (22%, 4/18). Collectively, 77.4% (24/31) of respondents experienced a decline in blood availability, ranging from 10% to 50%. Contributing factors included public fear of COVID-19 (21/24); stay-at-home measures (18/24); logistics (14/24); and canceled blood drives (16/24). Adaptations included increased collaboration within and between institutions (17/27), donor eligibility changes (21/31); social media or phone promotion (22/39); and replacement donation (3/27). Fifteen of 31 responses reported CCP donation (48.4%); CCP transfusion occurred in 6 (19.4%). The primary barrier was engaging recovered patients for donation (7/15). Conclusion: Our survey describes challenges experienced by LMIC blood systems during the COVID-19 pandemic. While the decline in blood supplies was severe, adaptive measures included collaboration, outreach, and CCP programs.
MeSH term(s)	Blood Donors/supply & distribution ; Blood Transfusion ; COVID-19 ; Cross-Sectional Studies ; Developing Countries ; Humans ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.16798
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 284: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Managing blood supplies during natural disasters, humanitarian emergencies, and pandemics: lessons learned from COVID-19.

Van Denakker, Tayler A / Al-Riyami, Arwa Z / Feghali, Rita / Gammon, Richard / So-Osman, Cynthia / Crowe, Elizabeth P / Goel, Ruchika / Rai, Herleen / Tobian, Aaron A R / Bloch, Evan M

Expert review of hematology

2023 Volume 16, Issue 7, Page(s) 501–514

Abstract: Introduction: The COVID-19 pandemic has resulted in a historic public health crisis with widespread social and economic ramifications. The pandemic has also affected the blood supply, resulting in unprecedented and sustained blood shortages.: Areas ... ...

Abstract	Introduction: The COVID-19 pandemic has resulted in a historic public health crisis with widespread social and economic ramifications. The pandemic has also affected the blood supply, resulting in unprecedented and sustained blood shortages. Areas covered: This review describes the challenges of maintaining a safe and sufficient blood supply in the wake of natural disasters, humanitarian emergencies, and pandemics. The challenges, which are accentuated in low- and high-income countries, span the impact on human capacity (affecting blood donors and blood collections personnel alike), disruption to supply chains, and economic sustainability. COVID-19 imparted lessons on how to offset these challenges, which may be applied to future pandemics and public health crises. Expert opinion: Pandemic emergency preparedness plans should be implemented or revised by blood centers and hospitals to lessen the impact to the blood supply. Comprehensive planning should address the timely assessment of risk to the blood supply, rapid donor recruitment, and communication of need, measures to preserve safety for donors and operational staff, careful blood management, and resource sharing.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Emergencies ; Natural Disasters
Language	English
Publishing date	2023-05-09
Publishing country	England
Document type	Journal Article ; Review ; Research Support, N.I.H., Extramural
ZDB-ID	2516804-6
ISSN	1747-4094 ; 1747-4086
ISSN (online)	1747-4094
ISSN	1747-4086
DOI	10.1080/17474086.2023.2209716
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Zs.A 6943: Show issues

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Article ; Online: Preoperative Anemia is Associated with Increased Intraoperative Mortality in Patients Undergoing Cardiac Surgery

Arwa Z. Al-Riyami / Balan Baskaran / Sathiya M. Panchatcharam / Hilal Al-Sabti

Oman Medical Journal, Vol 36, Iss 3, Pp e267-e

2021 Volume 267

Abstract: Objectives: We sought to investigate the incidence of preoperative anemia in cardiac surgery and its association with outcomes. Methods: A retrospective review of clinical, laboratory, and transfusion data for all patients who underwent cardiac surgery ... ...

Abstract	Objectives: We sought to investigate the incidence of preoperative anemia in cardiac surgery and its association with outcomes. Methods: A retrospective review of clinical, laboratory, and transfusion data for all patients who underwent cardiac surgery at Sultan Qaboos University Hospital between 2008 and 2014 was performed. Patients were divided into two groups, anemic and non-anemic, with anemia defined as hemoglobin levels < 13 g/dL (males) and < 12 g/dL (females). Clinical variables were compared using chi-square and independent t-test. Factors influencing preoperative mortality were analyzed using multivariate binary logistics regression. Results: A total of 599 patients (69.9% males and 30.1% females) were included in the study; 69.3% underwent coronary artery bypass surgery. Preoperative anemia was found in 76.1% of females and 26.7% of male patients. Rates of intraoperative red blood cell transfusions were higher among anemic patients (75.9% vs. 52.3%, p < 0.001). Anemic patients had a worse risk profile with higher incidence of diabetes mellitus (53.8% vs. 38.9%, p < 0.001), congestive heart failure (51.4% vs. 28.3%, p < 0.001), arrhythmia (16.5% vs. 8.6%, p =0.004), and cerebrovascular disease (10.0% vs. 4.9%, p =0.015). In addition, they had a higher risk of overall mortality (6.4% vs. 2.6%, p =0.023). Preoperative anemia remained a risk factor for intraoperative mortality after logistic regression (odds ratio = 4.08, 95% confidence interval: 1.43–11.66; p= 0.009). Conclusions: Preoperative anemia in cardiac surgery is independently associated with increased intraoperative mortality and early readmission rates post-surgery.
Keywords	retrospective studies ; blood transfusion ; anemia ; cardiac surgical procedures ; Medicine ; R
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Oman Medical Specialty Board
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preoperative Anemia is Associated with Increased Intraoperative Mortality in Patients Undergoing Cardiac Surgery

Arwa Z. Al-Riyami / Balan Baskaran / Sathiya M. Panchatcharam / Hilal Al-Sabti

Oman Medical Journal, Vol 36, Iss 3, Pp e267-e

2021 Volume 267

Abstract	Objectives: We sought to investigate the incidence of preoperative anemia in cardiac surgery and its association with outcomes. Methods: A retrospective review of clinical, laboratory, and transfusion data for all patients who underwent cardiac surgery at Sultan Qaboos University Hospital between 2008 and 2014 was performed. Patients were divided into two groups, anemic and non-anemic, with anemia defined as hemoglobin levels < 13 g/dL (males) and < 12 g/dL (females). Clinical variables were compared using chi-square and independent t-test. Factors influencing preoperative mortality were analyzed using multivariate binary logistics regression. Results: A total of 599 patients (69.9% males and 30.1% females) were included in the study; 69.3% underwent coronary artery bypass surgery. Preoperative anemia was found in 76.1% of females and 26.7% of male patients. Rates of intraoperative red blood cell transfusions were higher among anemic patients (75.9% vs. 52.3%, p < 0.001). Anemic patients had a worse risk profile with higher incidence of diabetes mellitus (53.8% vs. 38.9%, p < 0.001), congestive heart failure (51.4% vs. 28.3%, p < 0.001), arrhythmia (16.5% vs. 8.6%, p =0.004), and cerebrovascular disease (10.0% vs. 4.9%, p =0.015). In addition, they had a higher risk of overall mortality (6.4% vs. 2.6%, p =0.023). Preoperative anemia remained a risk factor for intraoperative mortality after logistic regression (odds ratio = 4.08, 95% confidence interval: 1.43–11.66; p= 0.009). Conclusions: Preoperative anemia in cardiac surgery is independently associated with increased intraoperative mortality and early readmission rates post-surgery.
Keywords	retrospective studies ; blood transfusion ; anemia ; cardiac surgical procedures ; Medicine ; R
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Oman Medical Specialty Board
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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