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  1. Article ; Online: A Randomized, Phase 3, Double-Blind, Crossover Comparison of Multilayer, Extended-Release Methylphenidate (PRC-063), and Lisdexamfetamine in the Driving Performance of Young Adults With ADHD.

    Madaan, Vishal / Bhaskar, Sailaja / Donnelly, Graeme A E / Cox, Daniel J

    Journal of attention disorders

    2024  Volume 28, Issue 6, Page(s) 947–956

    Abstract: Objective: To compare PRC-063 (multilayer-release methylphenidate) and lisdexamfetamine dimesylate (LDX) on the driving performance of young adults with attention deficit hyperactivity disorder (ADHD) in a randomized, double-blind, crossover study.: ... ...

    Abstract Objective: To compare PRC-063 (multilayer-release methylphenidate) and lisdexamfetamine dimesylate (LDX) on the driving performance of young adults with attention deficit hyperactivity disorder (ADHD) in a randomized, double-blind, crossover study.
    Method: Following up to 21 days of each treatment in each treatment course (PRC-063/LDX or LDX/PRC-063), subjects completed a 15-hour driving simulator laboratory assessment. The primary outcome measure was the Tactical Driving Quotient (TDQ) and the Clinical Global Impressions-Improvement (CGI-I) scale was a secondary outcome measure.
    Results: Forty-four subjects completed the study. PRC-063 and LDX had equivalent effects on driving performance through a 15-hour time period (least square mean difference -0.3 [standard error 1.08], 95% confidence interval [-2.4, 1.8],
    Conclusions: PRC-063 and LDX had comparable effects on driving performance, from 1 through 15 hours, the last time point measured.
    MeSH term(s) Humans ; Young Adult ; Attention Deficit Disorder with Hyperactivity/drug therapy ; Attention Deficit Disorder with Hyperactivity/chemically induced ; Central Nervous System Stimulants/therapeutic use ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Lisdexamfetamine Dimesylate/therapeutic use ; Methylphenidate/therapeutic use ; Treatment Outcome
    Chemical Substances Central Nervous System Stimulants ; Lisdexamfetamine Dimesylate (SJT761GEGS) ; Methylphenidate (207ZZ9QZ49)
    Language English
    Publishing date 2024-02-25
    Publishing country United States
    Document type Clinical Trial, Phase III ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 2004350-8
    ISSN 1557-1246 ; 1087-0547
    ISSN (online) 1557-1246
    ISSN 1087-0547
    DOI 10.1177/10870547241226634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5196: Show issues Location:
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  2. Article ; Online: New Ways to Support the Recruitment of International Medical Graduates During the Pandemic.

    Khan, Manal / Madaan, Vishal

    Academic medicine : journal of the Association of American Medical Colleges

    2021  Volume 96, Issue 5, Page(s) 616

    MeSH term(s) COVID-19/epidemiology ; Foreign Medical Graduates ; Humans ; Internship and Residency ; Interviews as Topic/methods ; Pandemics ; Personnel Selection ; Physicians/supply & distribution ; SARS-CoV-2 ; United States
    Language English
    Publishing date 2021-07-27
    Publishing country United States
    Document type Letter
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000003980
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  3. Article ; Online: Non-US International Medical Graduates in Psychiatry Training During the COVID-19 Pandemic: Challenges and Novel Solutions.

    Elnajjar, Alaa / Khan, Manal / Foongsathaporn, Chayanin / Lu, Francis / Madaan, Vishal

    Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

    2022  Volume 47, Issue 2, Page(s) 205–210

    MeSH term(s) Humans ; COVID-19 ; Pandemics ; Education, Medical ; Psychiatry/education ; Foreign Medical Graduates
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Editorial
    ZDB-ID 1045331-3
    ISSN 1545-7230 ; 1042-9670
    ISSN (online) 1545-7230
    ISSN 1042-9670
    DOI 10.1007/s40596-022-01621-4
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  4. Article ; Online: Development Assessment Scale for Indian Infants: A Systematic Review and Perspective on Dwindling Cutoffs.

    Madaan, Priyanka / Saini, Lokesh / Sondhi, Vishal

    Indian journal of pediatrics

    2021  Volume 88, Issue 9, Page(s) 918–920

    Abstract: The Developmental Assessment Scale for Indian Infants (DASII) remains the mainstay in India for diagnostic confirmation and validation of upcoming screening tools for development in infants and toddlers. This is an Indian adaptation of Bayley Scales of ... ...

    Abstract The Developmental Assessment Scale for Indian Infants (DASII) remains the mainstay in India for diagnostic confirmation and validation of upcoming screening tools for development in infants and toddlers. This is an Indian adaptation of Bayley Scales of Infant Development which is the globally accepted gold standard. However, the DASII cutoff points used for categorizing development and distinguishing normal from abnormal development are not in agreement across different studies conducted over the last two decades in India. This is probably due to a lack of mention of cutoff points in the DASII manual and existing literature. The current systematic review summarizes the heterogeneity in literature for interpretation of DASII and its cutoff points. Also, a perspective on the ideal cutoff points is presented.
    MeSH term(s) Asian Continental Ancestry Group ; Child ; Child Development ; Developmental Disabilities ; Humans ; India ; Infant ; Mass Screening
    Language English
    Publishing date 2021-02-08
    Publishing country India
    Document type Journal Article ; Systematic Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-03671-2
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  5. Article ; Online: Distracted Driving With Attention-Deficit/Hyperactivity Disorder.

    Madaan, Vishal / Cox, Daniel J

    JAMA psychiatry

    2017  Volume 74, Issue 6, Page(s) 603–604

    MeSH term(s) Accidents, Traffic ; Attention Deficit Disorder with Hyperactivity ; Automobile Driving ; Distracted Driving ; Humans ; Motor Vehicles
    Language English
    Publishing date 2017-05-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2017.0864
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  6. Article: Risperidone: a review of efficacy studies in adolescents with schizophrenia.

    Madaan, Vishal

    Drugs of today (Barcelona, Spain : 1998)

    2009  Volume 45, Issue 1, Page(s) 55–62

    Abstract: Risperidone has been approved by the Food and Drug Administration for the treatment of schizophrenia in the adolescent population. This new indication has been a result of data obtained from two pivotal double-blind trials with supplemental information ... ...

    Abstract Risperidone has been approved by the Food and Drug Administration for the treatment of schizophrenia in the adolescent population. This new indication has been a result of data obtained from two pivotal double-blind trials with supplemental information from open-label and retrospective trials. This brief article provides an overview of risperidone's pharmacological profile followed by information on the double-blind trials that have resulted in the approval of risperidone for the treatment of adolescent schizophrenia.
    MeSH term(s) Adolescent ; Antipsychotic Agents/adverse effects ; Antipsychotic Agents/pharmacokinetics ; Antipsychotic Agents/therapeutic use ; Clinical Trials as Topic ; Humans ; Risperidone/adverse effects ; Risperidone/pharmacokinetics ; Risperidone/therapeutic use ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents ; Risperidone (L6UH7ZF8HC)
    Language English
    Publishing date 2009-01
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2009.45.1.1315074
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  7. Article: Lisdexamfetamine dimesylate for childhood ADHD.

    Madaan, Vishal

    Drugs of today (Barcelona, Spain : 1998)

    2008  Volume 44, Issue 5, Page(s) 319–324

    Abstract: Stimulants are extremely effective and safe and have been the mainstay for the pharmacological treatment of attention deficit hyperactivity disorder (ADHD) for many years. However, there have been some concerns regarding their abuse, especially by ... ...

    Abstract Stimulants are extremely effective and safe and have been the mainstay for the pharmacological treatment of attention deficit hyperactivity disorder (ADHD) for many years. However, there have been some concerns regarding their abuse, especially by teenagers and young adults. Lisdexamfetamine was recently approved for the treatment of ADHD in 6-12-year-olds and provides a novel approach to the treatment of ADHD. Lisdexamfetamine is a prodrug comprised of dextroamphetamine covalently attached to an essential amino acid, L-lysine. Following oral administration, the amide linkage between the two molecules is enzymatically hydrolyzed in the gastrointestinal tract, thus releasing active dextroamphetamine, which mediates the therapeutic effect in a fashion similar to other stimulants. The parent drug does not bind to sites responsible for the reuptake of norepinephrine and dopamine in vitro. Lisdexamfetamine does not produce high dextroamphetamine levels when injected or snorted, and thus may have lower abuse potential compared to conventional stimulants. Lisdexamfetamine appears to have efficacy and tolerability comparable to other extended-release stimulant formulations used to treat ADHD, but reduced potential for abuse-related liking effects. Compared to equivalent amounts of immediate-release dextroamphetamine.
    MeSH term(s) Attention Deficit Disorder with Hyperactivity/drug therapy ; Child ; Clinical Trials as Topic ; Dextroamphetamine/adverse effects ; Dextroamphetamine/pharmacokinetics ; Dextroamphetamine/pharmacology ; Dextroamphetamine/therapeutic use ; Humans ; Lisdexamfetamine Dimesylate
    Chemical Substances Lisdexamfetamine Dimesylate (SJT761GEGS) ; Dextroamphetamine (TZ47U051FI)
    Language English
    Publishing date 2008-05
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2008.44.5.1215724
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  8. Article ; Online: By fault or by default.

    Madaan, Vishal / Bestha, Durga Prasad

    Frontiers in psychiatry

    2012  Volume 3, Page(s) 27

    Language English
    Publishing date 2012-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640 ; 1664-0640
    ISSN (online) 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2012.00027
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  9. Article ; Online: Clonidine and auditory hallucinations.

    Bestha, Durga Prasad / Madaan, Vishal

    Innovations in clinical neuroscience

    2012  Volume 9, Issue 9, Page(s) 10

    Language English
    Publishing date 2012-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675366-2
    ISSN 2158-8341 ; 2158-8341
    ISSN (online) 2158-8341
    ISSN 2158-8341
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  10. Article ; Online: Underrepresented in Medicine Recruitment: Rationale, Challenges, and Strategies for Increasing Diversity in Psychiatry Residency Programs.

    Pierre, Joseph M / Mahr, Fauzia / Carter, Andrea / Madaan, Vishal

    Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

    2017  Volume 41, Issue 2, Page(s) 226–232

    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1045331-3
    ISSN 1545-7230 ; 1042-9670
    ISSN (online) 1545-7230
    ISSN 1042-9670
    DOI 10.1007/s40596-016-0499-x
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