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  1. Article ; Online: Reply to Riuko Ohashi, Arndt Hartmann, Holger Moch, and Guido Martignoni's Letter to the Editor re: Svetlana Avulova, John C. Cheville, Christine M. Lohse, et al. Grading of Chromophobe Renal Cell Carcinoma: Evidence for a Four-tiered Classification Incorporating Coagulative Tumor Necrosis. Eur Urol 2021;79:225-31: Two-, Three-, or Four-tiered Grading of Chromophobe Renal Cancer: That's the Question!

    Avulova, Svetlana / Cheville, John C / Lohse, Christine M / Thompson, R Houston / Potretzke, Aaron M

    European urology

    2021  Volume 80, Issue 1, Page(s) e19

    MeSH term(s) Carcinoma, Renal Cell/surgery ; Humans ; Kidney Neoplasms/surgery ; Necrosis ; Nephrectomy
    Language English
    Publishing date 2021-04-17
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Re: Location of extrarenal tumor extension does not impact survival of patients with pT3a renal cell carcinoma. V. Margulis, P. Tamboli, S. F. Matin, M. Meisner, D. A. Swanson and C. G. Wood. J Urol 2007; 178: 1878-1882.

    Thompson, R Houston / Cheville, John C / Leibovich, Bradley C / Blute, Michael L

    The Journal of urology

    2008  Volume 180, Issue 1, Page(s) 409; author reply 409–10

    MeSH term(s) Carcinoma, Renal Cell/mortality ; Carcinoma, Renal Cell/pathology ; Humans ; Kidney Neoplasms/mortality ; Kidney Neoplasms/pathology ; Neoplasm Invasiveness ; Neoplasm Staging ; Survival Rate
    Language English
    Publishing date 2008-07
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2008.03.073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Temperament in Toddlers With and Without Prelingual Hearing Loss.

    Castellanos, Irina / Houston, Derek M

    Journal of speech, language, and hearing research : JSLHR

    2023  Volume 67, Issue 1, Page(s) 232–243

    Abstract: ... b) examine possible associations between temperament, demographic, and communication factors; and (c ...

    Abstract Purpose: The purpose of this study is to examine parent-reported ratings of temperament in toddlers with and without prelingual hearing loss.
    Method: The parent-completed Early Childhood Behavior Questionnaire (ECBQ) was used to assess temperament in toddlers aged 18-36 months. Three dimensions of temperament were examined: surgency, negative affectivity, and effortful control. Analyses were conducted to (a) examine differences in temperament across toddlers with and without prelingual hearing loss; (b) examine possible associations between temperament, demographic, and communication factors; and (c) determine if the ECBQ is sensitive to differences in hearing, communication, and listening skills among toddlers with prelingual hearing loss.
    Results: The parent-completed ECBQ revealed that toddlers with prelingual hearing loss differed from their hearing peers on some but not all dimensions of temperament. Specifically, children with prelingual hearing loss were rated as displaying higher levels of surgency and lower levels of effortful control but comparable levels of negative affectivity when compared to their hearing peers. Regression analyses revealed that chronological age and communication strategy predicted scores of effortful control in toddlers with prelingual hearing loss, whereas chronological age alone predicted scores of effortful control in toddlers with hearing. Finally, the ECBQ appears to contain "listening" items that skew (lower) levels of effortful control in toddlers with prelingual hearing loss, such that only the group effect of higher levels of surgency remained after removing these "listening" items. Correlations between the original and our modified ECBQ (removing the "listening" items) revealed strong associations, reflective of high construct validity.
    Conclusions: This was the first study to measure temperament in toddlers with prelingual hearing loss using the ECBQ. Our results revealed differences between children with and without prelingual hearing loss centering on the dimension of surgency. Examining differences in temperament during the toddler period of development may be particularly important and useful for predicting functional outcomes following prelingual hearing loss.
    MeSH term(s) Humans ; Child, Preschool ; Child ; Temperament ; Child Behavior ; Parents ; Communication ; Hearing Loss
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1364086-0
    ISSN 1558-9102 ; 1092-4388
    ISSN (online) 1558-9102
    ISSN 1092-4388
    DOI 10.1044/2023_JSLHR-23-00182
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  4. Article ; Online: Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists.

    Lea Houston, Matilda / Morgan, Jody / Kelso, Celine

    Mini reviews in medicinal chemistry

    2023  Volume 24, Issue 1, Page(s) 92–109

    Abstract: Background: Synthetic cannabinoid receptor agonists (SCRAs) are the most diverse class of new psychoactive substances worldwide, with approximately 300 unique SCRAs identified to date. While the use of this class of drug is not particularly prevalent, ... ...

    Abstract Background: Synthetic cannabinoid receptor agonists (SCRAs) are the most diverse class of new psychoactive substances worldwide, with approximately 300 unique SCRAs identified to date. While the use of this class of drug is not particularly prevalent, SCRAs are associated with several deaths every year due to their severe toxicity.
    Methods: A thorough examination of the literature identified 15 new SCRAs with a significant clinical impact between 2015 and 2021.
    Results: These 15 SCRAs have been implicated in 154 hospitalizations and 209 deaths across the US, Europe, Asia, and Australasia during this time period.
    Conclusion: This narrative review provides pharmacodynamic, pharmacokinetic, and toxicologic data for SCRAs as a drug class, including an in-depth review of known pharmacological properties of 15 recently identified and emerging SCRAs for the benefit of researchers, policy makers, and clinicians who wish to be informed of developments in this field.
    MeSH term(s) Cannabinoid Receptor Agonists/pharmacology ; Asia
    Chemical Substances Cannabinoid Receptor Agonists
    Language English
    Publishing date 2023-05-12
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2104081-3
    ISSN 1875-5607 ; 1389-5575
    ISSN (online) 1875-5607
    ISSN 1389-5575
    DOI 10.2174/1389557523666230515163107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply by Authors.

    Houston Thompson, R / Lohse, Christine M / Leibovich, Bradley C / Gettman, Matthew T / Husmann, Douglas A / Viers, Boyd R

    Urology

    2024  

    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Letter
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2024.03.014
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  6. Article ; Online: Tree Nut and Peanut Consumption and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Houston, Lauren / Probst, Yasmine C / Chandra Singh, Mamatha / Neale, Elizabeth P

    Advances in nutrition (Bethesda, Md.)

    2023  Volume 14, Issue 5, Page(s) 1029–1049

    Abstract: Cardiovascular disease (CVD) is the leading cause of death globally. Habitual consumption of tree nuts and peanuts is associated with cardioprotective benefits. Food-based dietary guidelines globally recommend nuts as a key component of a healthy diet. ... ...

    Abstract Cardiovascular disease (CVD) is the leading cause of death globally. Habitual consumption of tree nuts and peanuts is associated with cardioprotective benefits. Food-based dietary guidelines globally recommend nuts as a key component of a healthy diet. This systematic review and meta-analysis were conducted to examine the relationship between tree nut and peanut consumption and risk factors for CVD in randomized controlled trials (RCTs) (PROSPERO: CRD42022309156). MEDLINE, PubMed, CINAHL, and Cochrane Central databases were searched up to 26 September, 2021. All RCT studies that assessed the effects of tree nut or peanut consumption of any dose on CVD risk factors were included. Review Manager software was used to conduct a random effect meta-analysis for CVD outcomes from RCTs. Forest plots were generated for each outcome, between-study heterogeneity was estimated using the I
    MeSH term(s) Humans ; Cardiovascular Diseases/prevention & control ; Cardiovascular Diseases/etiology ; Nuts ; Arachis ; Cholesterol, LDL ; Cholesterol, HDL ; Randomized Controlled Trials as Topic ; Cholesterol ; Triglycerides ; Apolipoproteins B
    Chemical Substances Cholesterol, LDL ; Cholesterol, HDL ; Cholesterol (97C5T2UQ7J) ; Triglycerides ; Apolipoproteins B
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2583634-1
    ISSN 2156-5376 ; 2156-5376
    ISSN (online) 2156-5376
    ISSN 2156-5376
    DOI 10.1016/j.advnut.2023.05.004
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  7. Article ; Online: Alcohol use during the COVID-19 pandemic: gender, parenthood, intimate partner violence, and stress.

    Colton, Kassidy C / Godleski, Stephanie A / Baschnagel, Joseph S / Houston, Rebecca J / DeHarder, Shine M

    AIMS public health

    2023  Volume 10, Issue 2, Page(s) 360–377

    Abstract: Some preliminary work during the COVID-19 pandemic indicates that adult alcohol use increased, particularly for parents. This cross-sectional study examined the quantity and frequency of adults' alcohol use during the early stages of the pandemic. ... ...

    Abstract Some preliminary work during the COVID-19 pandemic indicates that adult alcohol use increased, particularly for parents. This cross-sectional study examined the quantity and frequency of adults' alcohol use during the early stages of the pandemic. Additionally, the influences of gender, parenthood, COVID-19-related stressors and intimate partner violence (IPV) on alcohol consumption were examined. The sample consisted of 298 adults (98 parents) from across the United States who completed self-report surveys through Qualtrics at the beginning of the pandemic in May 2020. In the present study, all men reported higher levels of drinking compared to all women. Although stress levels did not impact alcohol consumption, findings indicate that increased IPV experiences were associated with higher levels of heavy drinking during the pandemic. Results also suggested that having children in the home particularly impacted drinking levels during the pandemic, above and beyond the influence of gender, IPV, and stress levels. These findings suggest that parenthood may have had a cascading influence on drinking experiences during the COVID-19 pandemic. Implications and recommendations for further research are discussed.
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2777115-5
    ISSN 2327-8994 ; 2327-8994
    ISSN (online) 2327-8994
    ISSN 2327-8994
    DOI 10.3934/publichealth.2023027
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  8. Article ; Online: Diminished airway host innate response in people with cystic fibrosis who experience frequent pulmonary exacerbations.

    Houston, Claire J / Alkhatib, Aya / Einarsson, Gísli G / Tunney, Michael M / Taggart, Clifford C / Downey, Damian G

    The European respiratory journal

    2024  Volume 63, Issue 2

    Abstract: Rationale: Pulmonary exacerbations are clinically impactful events that accelerate cystic fibrosis (CF) lung disease progression. The pathophysiological mechanisms underlying an increased frequency of pulmonary exacerbations have not been explored.: ... ...

    Abstract Rationale: Pulmonary exacerbations are clinically impactful events that accelerate cystic fibrosis (CF) lung disease progression. The pathophysiological mechanisms underlying an increased frequency of pulmonary exacerbations have not been explored.
    Objectives: To compare host immune response during intravenous antibiotic treatment of pulmonary exacerbations in people with CF who have a history of frequent
    Methods: Adults with CF were recruited at onset of antibiotic treatment of a pulmonary exacerbation and were categorised as infrequent or frequent exacerbators based on their pulmonary exacerbation frequency in the previous 12 months. Clinical parameters, sputum bacterial load and sputum inflammatory markers were measured on day 0, day 5 and at the end of treatment. Shotgun proteomic analysis was performed on sputum using liquid chromatography-mass spectrometry.
    Measurements and main results: Many sputum proteins were differentially enriched between infrequent and frequent exacerbators (day 0 n=23 and day 5 n=31). The majority of these proteins had a higher abundance in infrequent exacerbators and were secreted innate host defence proteins with antimicrobial, antiprotease and immunomodulatory functions. Several differentially enriched proteins were validated using ELISA and Western blot including secretory leukocyte protease inhibitor (SLPI), lipocalin-1 and cystatin SA. Sputum from frequent exacerbators demonstrated potent ability to cleave exogenous recombinant SLPI in a neutrophil elastase dependent manner. Frequent exacerbators had increased sputum inflammatory markers (interleukin (IL)-1β and IL-8) and total bacterial load compared to infrequent exacerbators.
    Conclusions: A diminished innate host protein defence may play a role in the pathophysiological mechanisms of frequent CF pulmonary exacerbations. Frequent exacerbators may benefit from therapies targeting this dysregulated host immune response.
    MeSH term(s) Adult ; Humans ; Cystic Fibrosis/complications ; Proteomics ; Lung ; Sputum/chemistry ; Anti-Bacterial Agents/therapeutic use ; Disease Progression
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01228-2023
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  9. Article ; Online: Recruitment, retention, and experiences of Australian male dietitians: A cross-sectional online survey.

    Stefoska-Needham, Anita / Weber, Christopher M / Beck, Eleanor J / Craddock, Joel C / Houston, Lauren A

    Nutrition & dietetics: the journal of the Dietitians Association of Australia

    2023  Volume 81, Issue 2, Page(s) 160–169

    Abstract: Aim: Male dietitians are under-represented in the global dietetics workforce, including in Australia. This study explores Australian males' experiences as dietitians in the Australian workforce, with the aim to identify influences that initially ... ...

    Abstract Aim: Male dietitians are under-represented in the global dietetics workforce, including in Australia. This study explores Australian males' experiences as dietitians in the Australian workforce, with the aim to identify influences that initially attracted them to dietetics, as well as barriers that may affect their decision to stay in or leave the profession.
    Methods: A cross-sectional, semi-quantitative web-based survey was distributed to male dietitians using purposive, snowball sampling. Closed and open-ended questions were included. Descriptive statistics were generated, and content analysis of free-text responses identified major themes.
    Results: Seventy-one respondents opened the survey link, of which 65 respondents attempted the survey. Fifty-four (83.1%) respondents agreed that dietetics is female-dominated. An interest in food and nutrition was the most reported reason for studying dietetics (73.8%). Of the 55 respondents who were not intending to retire in the next 5 years, 15 (27.3%) stated they were somewhat or extremely likely to leave the profession of dietetics. Respondents identified issues that impacted their experiences as a male dietitian, including gender differences, a lack of male role models, barriers to career progression/employment, and perceptions of a lack of respect and impact within healthcare.
    Conclusions: Australian male dietitians perceive systemic, social, and personal factors that have influenced their career experiences. Greater exposure to prominent male role models may be self-perpetuating in improving male dietitian recruitment and eventually, retention. A multi-pronged approach is needed to improve the rate of recruitment of male dietitians, with a role for tertiary education providers and peak dietetics bodies.
    MeSH term(s) Humans ; Male ; Cross-Sectional Studies ; Australia ; Nutritionists ; Adult ; Surveys and Questionnaires ; Middle Aged ; Dietetics ; Career Choice ; Personnel Selection ; Female
    Language English
    Publishing date 2023-12-19
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2082047-1
    ISSN 1747-0080 ; 1446-6368
    ISSN (online) 1747-0080
    ISSN 1446-6368
    DOI 10.1111/1747-0080.12858
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  10. Article: Niche partitioning and the storage effect facilitate coexistence in an amphibian community.

    Brooks, George C / Caruso, Nicholas M / Chandler, Houston C / Haas, Carola A

    Ecology and evolution

    2023  Volume 13, Issue 10, Page(s) e10629

    Abstract: Virtually all natural community assemblages are dominated by a handful of common species. Dominant species can exert negative impacts on biodiversity through competitive exclusion, and thus there is a strong incentive to understand imbalances in ... ...

    Abstract Virtually all natural community assemblages are dominated by a handful of common species. Dominant species can exert negative impacts on biodiversity through competitive exclusion, and thus there is a strong incentive to understand imbalances in community composition, changes in dominance hierarchies through time, and mechanisms of coexistence. Pond-breeding amphibians that utilize ephemeral wetlands provide an excellent opportunity to evaluate theoretical predictions of community composition in stochastic environments. One of the most striking features of pond-breeding amphibians is the marked stochastic fluctuations in abundance across years. Given strong theoretical and empirical links between evenness and biomass, one would expect community evenness to change from year to year. Moreover, if different species exhibit different boom-and-bust reproductive cycles, then a storage effect may help to explain why one species does not outcompete all others. Here, we explore the interplay between biotic and abiotic conditions in shaping amphibian communities at two ephemeral wetlands on Eglin Air Force Base, Florida. We document consistent community composition over 6 years of monitoring, resulting from a lack of species turnover and similar responses of all community members to environmental conditions. The similar dynamics of species argues against a storage effect as the sole mechanism for coexistence and instead points to niche partitioning as a more important factor. In support of this conclusion, we show that the degree of synchrony in breeding migrations only correlates with environmental conditions within species, not between species. The lack of pattern seen between species implies that individuals are somewhat constrained in the timing of breeding migrations, perhaps owing in part to competition with other community members. We hope that our work reinvigorates interest in amphibian communities and highlights ephemeral wetlands as model systems to study community dynamics in stochastic environments.
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.10629
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