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  1. Article: Fecal microbiota transplantation for recurrent

    Sandhu, Avnish / Chopra, Teena

    Therapeutic advances in gastroenterology

    2021  Volume 14, Page(s) 17562848211053105

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2021-12-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2440710-0
    ISSN 1756-2848 ; 1756-283X
    ISSN (online) 1756-2848
    ISSN 1756-283X
    DOI 10.1177/17562848211053105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cutaneous metastatic pancreatic adenocarcinoma.

    Nasser, Sarah / Husseini, Abraham / Pasula, Shirisha / Sandhu, Avnish

    BMJ case reports

    2021  Volume 14, Issue 11

    MeSH term(s) Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/drug therapy ; Administration, Cutaneous ; Humans ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/drug therapy ; Skin ; Skin Neoplasms/drug therapy
    Language English
    Publishing date 2021-11-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-245657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Novel Combination Therapy for Extensively Drug-Resistant

    Holger, Dana J / Kunz Coyne, Ashlan J / Zhao, Jing J / Sandhu, Avnish / Salimnia, Hossein / Rybak, Michael J

    Open forum infectious diseases

    2022  Volume 9, Issue 4, Page(s) ofac092

    Abstract: We report our clinical and laboratory experience treating a 50-year-old patient who was critically ill with extensively drug- ... ...

    Abstract We report our clinical and laboratory experience treating a 50-year-old patient who was critically ill with extensively drug-resistant
    Language English
    Publishing date 2022-03-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Strategies for Effective Infection Prevention Programs: Structures, Processes, and Funding.

    Dhar, Sorabh / Sandhu, Avnish L / Valyko, Amanda / Kaye, Keith S / Washer, Laraine

    Infectious disease clinics of North America

    2021  Volume 35, Issue 3, Page(s) 531–551

    Abstract: Successful Infection Prevention Programs (IPPs) consist of a multidisciplinary team led by a hospital epidemiologist and managed by infection preventionists. Knowledge of the economics of health care-associated infections (HAIs) and the ability to make a ...

    Abstract Successful Infection Prevention Programs (IPPs) consist of a multidisciplinary team led by a hospital epidemiologist and managed by infection preventionists. Knowledge of the economics of health care-associated infections (HAIs) and the ability to make a business plan is now essential to the success of programs. Prevention of HAIs is the core function of IPPs with impact on patient outcomes, quality of care, and cost savings for hospitals. This article discusses the structure and responsibilities of an IPP, the regulatory pressures and opportunities that these programs face, and how to build and manage a successful program.
    MeSH term(s) Cross Infection/economics ; Cross Infection/prevention & control ; Disease Outbreaks/prevention & control ; Hospitals ; Humans ; Infection Control/economics ; Infection Control/methods ; Infection Control/organization & administration ; Program Development
    Language English
    Publishing date 2021-08-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1077676-x
    ISSN 1557-9824 ; 0891-5520
    ISSN (online) 1557-9824
    ISSN 0891-5520
    DOI 10.1016/j.idc.2021.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The argument for rapid influenza polymerase chain reaction (PCR) during the COVID-19 pandemic: Quicker turnaround times correlated with decreased antimicrobial use, reduced admission rates, and shorter length of stay.

    Sandhu, Avnish K / LeRose, Jennifer J / Garg, Alpana / Polistico, Jordan / Chopra, Teena

    Infection control and hospital epidemiology

    2021  Volume 43, Issue 5, Page(s) 654–656

    Abstract: The innovation of rapid influenza polymerase chain reaction (XT-PCR) has allowed quick, highly sensitive test results. Consequently, physicians can differentiate influenza from other respiratory illnesses and rapidly initiate treatment. We examined the ... ...

    Abstract The innovation of rapid influenza polymerase chain reaction (XT-PCR) has allowed quick, highly sensitive test results. Consequently, physicians can differentiate influenza from other respiratory illnesses and rapidly initiate treatment. We examined the effect of implementing XT-PCR on antimicrobial use, admission rates, and length of stay at a tertiary healthcare system.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; COVID-19/diagnosis ; Humans ; Influenza, Human/diagnosis ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Length of Stay ; Pandemics ; Polymerase Chain Reaction/methods
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.86
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Omadacycline: a therapeutic review of use in community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections.

    Chopra, Teena / Sandhu, Avnish / Theriault, Nicolette / Meehan, Joni / Tillotson, Glenn

    Future microbiology

    2020  Volume 15, Page(s) 1319–1333

    Abstract: Omadacycline is a novel aminomethylcycline antimicrobial, US FDA approved for the treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. It is not susceptible to common tetracycline resistance ... ...

    Abstract Omadacycline is a novel aminomethylcycline antimicrobial, US FDA approved for the treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. It is not susceptible to common tetracycline resistance mechanisms, and has demonstrated efficacy against a broad spectrum of pathogens including resistant isolates, which are increasing in prevalence and complexity. It is available in both intravenous and oral formats, and can be administered in single, once daily doses or multiple doses, with no dosing adjustments required for sex, age, hepatic or renal impairment. It can be a good option for patients with low treatment adherence, and oral therapy may be used to reduce length of hospitalization for iv. treatment. This article reviews the
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacokinetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteria/classification ; Bacteria/drug effects ; Bacteria/isolation & purification ; Clinical Trials as Topic ; Community-Acquired Infections/drug therapy ; Drug Resistance, Bacterial/drug effects ; Microbial Sensitivity Tests ; Pneumonia, Bacterial/drug therapy ; Safety ; Skin Diseases, Bacterial/drug therapy ; Tetracyclines/chemistry ; Tetracyclines/pharmacokinetics ; Tetracyclines/pharmacology ; Tetracyclines/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Tetracyclines ; omadacycline (090IP5RV8F)
    Language English
    Publishing date 2020-09-22
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2020-0182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA, March–April 2020

    Avnish Sandhu / Glenn Tillotson / Jordan Polistico / Hossein Salimnia / Mara Cranis / Judy Moshos / Lori Cullen / Lavina Jabbo / Lawrence Diebel / Teena Chopra

    Emerging Infectious Diseases, Vol 26, Iss 9, Pp 2272-

    2020  Volume 2274

    Abstract: We describe 9 patients at a medical center in Detroit, Michigan, USA, with severe acute respiratory syndrome coronavirus 2 and Clostridioides difficile. Both infections can manifest as digestive symptoms and merit screening when assessing patients with ... ...

    Abstract We describe 9 patients at a medical center in Detroit, Michigan, USA, with severe acute respiratory syndrome coronavirus 2 and Clostridioides difficile. Both infections can manifest as digestive symptoms and merit screening when assessing patients with diarrhea during the coronavirus disease pandemic. These co-infections also highlight the continued importance of antimicrobial stewardship.
    Keywords Clostridiodes difficile ; co-infection ; diarrhea ; COVID-19 ; coronavirus disease ; SARS-CoV-2 ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The role of the social vulnerability index in personal protective equipment shortages, number of cases, and associated mortality during the coronavirus disease 2019 (COVID-19) pandemic in Michigan skilled nursing facilities.

    LeRose, Jennifer J / Merlo, Courtney / Duong, Phong / Harden, Kelsi / Rush, Rebecca / Artzberger, Adam / Sidhu, Nikki / Sandhu, Avnish / Chopra, Teena

    Infection control and hospital epidemiology

    2020  Volume 42, Issue 7, Page(s) 877–880

    Abstract: The Social Vulnerability Index (SVI) is used to stratify community need for support during disasters. We evaluated relationships between the SVI and personal protective equipment shortages, COVID-19 caseload, and mortality rates in skilled nursing ... ...

    Abstract The Social Vulnerability Index (SVI) is used to stratify community need for support during disasters. We evaluated relationships between the SVI and personal protective equipment shortages, COVID-19 caseload, and mortality rates in skilled nursing facilities (SNFs). In SVI quartile 4, personal protective equipment shortages were 2.3 times those in SNFs in quartile 1; COVID-19 case loads were 1.6 times those of SNFs in quartile 1; and mortality rates in were 1.9 times those of SNFs in SVI quartile 1.
    MeSH term(s) COVID-19 ; Humans ; Michigan/epidemiology ; Pandemics ; Personal Protective Equipment ; SARS-CoV-2 ; Skilled Nursing Facilities
    Keywords covid19
    Language English
    Publishing date 2020-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.1318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA, March-April 2020.

    Sandhu, Avnish / Tillotson, Glenn / Polistico, Jordan / Salimnia, Hossein / Cranis, Mara / Moshos, Judy / Cullen, Lori / Jabbo, Lavina / Diebel, Lawrence / Chopra, Teena

    Emerging infectious diseases

    2020  Volume 26, Issue 9

    Abstract: We describe 9 patients at a medical center in Detroit, Michigan, USA, with severe acute respiratory syndrome coronavirus 2 and Clostridioides difficile. Both infections can manifest as digestive symptoms and merit screening when assessing patients with ... ...

    Abstract We describe 9 patients at a medical center in Detroit, Michigan, USA, with severe acute respiratory syndrome coronavirus 2 and Clostridioides difficile. Both infections can manifest as digestive symptoms and merit screening when assessing patients with diarrhea during the coronavirus disease pandemic. These co-infections also highlight the continued importance of antimicrobial stewardship.
    MeSH term(s) Adult ; Aged ; Anti-Bacterial Agents/adverse effects ; Antimicrobial Stewardship ; Betacoronavirus ; COVID-19 ; Clostridioides difficile ; Clostridium Infections/chemically induced ; Clostridium Infections/epidemiology ; Clostridium Infections/microbiology ; Coinfection/epidemiology ; Coinfection/microbiology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/microbiology ; Female ; Humans ; Male ; Michigan/epidemiology ; Middle Aged ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/microbiology ; Population Surveillance ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents
    Keywords covid19
    Language English
    Publishing date 2020-05-22
    Publishing country United States
    Document type Letter
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2609.202126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pandemic response gaps: Infection prevention and control lessons learned during coronavirus disease 2019 (COVID-19) outbreaks in skilled nursing facilities in Detroit, Michigan.

    Sandhu, Avnish / Polistico, Jordan Micah F / Meyer, Monica P / Gonzalez, Gonzalo / Kiama, Keith / Lebednick, Mark / Prentiss, Tyler / Misikir, Helina / Heinonen, Jessica / Zervos, John / Kilgore, Paul E / Zervos, Marcus J / Fink, Lauren R / Rehman, Najibah K / Maples, Catherine / Chopra, Teena

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 6, Page(s) 915–919

    Abstract: Background: Hospitalizations among skilled nursing facility (SNF) residents in Detroit increased in mid-March 2020 due to the coronavirus disease 2019 (COVID-19) pandemic. Outbreak response teams were deployed from local healthcare systems, the Centers ... ...

    Abstract Background: Hospitalizations among skilled nursing facility (SNF) residents in Detroit increased in mid-March 2020 due to the coronavirus disease 2019 (COVID-19) pandemic. Outbreak response teams were deployed from local healthcare systems, the Centers for Disease Control and Prevention (CDC), and the Detroit Health Department (DHD) to understand the infection prevention and control (IPC) gaps in SNFs that may have accelerated the outbreak.
    Methods: We conducted 2 point-prevalence surveys (PPS-1 and PPS-2) at 13 Detroit SNFs from April 8 to May 8, 2020. The DHD and partners conducted facility-wide severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing of all residents and staff and collected information regarding resident cohorting, staff cohorting, and personnel protective equipment (PPE) utilized during that time.
    Results: Resident cohorting had been implemented in 7 of 13 (58.3%) SNFs prior to point-prevalence survey 1 (PPS-1), and other facilities initiated cohorting after obtaining PPS-1 results. Cohorting protocols of healthcare practitioners and environmental service staff were not established in 4 (31%) of 13 facilities, and in 3 facilities (23.1%) the ancillary staff were not assigned to cohorts. Also, 2 SNFs (15%) had an observation unit prior to PPS-1, 2 (15%) had an observation unit after PPS-1, 4 (31%) could not establish an observation unit due to inadequate space, and 5 (38.4%) created an observation unit after PPS-2.
    Conclusion: On-site consultations identified gaps in IPC knowledge and cohorting that may have contributed to ongoing transmission of SARS-CoV-2 among SNF residents despite aggressive testing measures. Infection preventionists (IPs) are critical in guiding ongoing IPC practices in SNFs to reduce spread of COVID-19 through response and prevention.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Skilled Nursing Facilities ; Michigan/epidemiology ; SARS-CoV-2 ; Pandemics/prevention & control ; Disease Outbreaks/prevention & control
    Language English
    Publishing date 2022-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2022.181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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