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  1. Article: After the acute crisis - engaging people with psychosis in rehabilitation-oriented care.

    Siskind, Dan / Yung, Alison

    World psychiatry : official journal of the World Psychiatric Association (WPA)

    2022  Volume 21, Issue 2, Page(s) 246–247

    Language English
    Publishing date 2022-05-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2236130-3
    ISSN 2051-5545 ; 1723-8617
    ISSN (online) 2051-5545
    ISSN 1723-8617
    DOI 10.1002/wps.20970
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  2. Article ; Online: Making meaning of multimorbidity and severe mental illness: A viewpoint.

    Halstead, Sean / Siskind, Dan / Warren, Nicola

    The Australian and New Zealand journal of psychiatry

    2023  Volume 58, Issue 1, Page(s) 12–20

    Abstract: People living with severe mental illness, such as schizophrenia and bipolar affective disorder, frequently experience poorer physical health compared to those without mental illness. This issue has hitherto been approached through the disease-centred ... ...

    Abstract People living with severe mental illness, such as schizophrenia and bipolar affective disorder, frequently experience poorer physical health compared to those without mental illness. This issue has hitherto been approached through the disease-centred construct of
    MeSH term(s) Humans ; Multimorbidity ; Mental Disorders/epidemiology ; Schizophrenia/epidemiology ; Bipolar Disorder/epidemiology ; Comorbidity ; Chronic Disease
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 221140-3
    ISSN 1440-1614 ; 0004-8674
    ISSN (online) 1440-1614
    ISSN 0004-8674
    DOI 10.1177/00048674231195560
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  3. Article ; Online: Excess mortality from cancer in people with mental illness-Out of sight and out of mind.

    Kisely, Stephen / Siskind, Dan

    Acta psychiatrica Scandinavica

    2021  Volume 144, Issue 4, Page(s) 315–317

    MeSH term(s) Humans ; Mental Disorders/epidemiology ; Neoplasms/epidemiology
    Language English
    Publishing date 2021-09-22
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 103-x
    ISSN 1600-0447 ; 0001-690X
    ISSN (online) 1600-0447
    ISSN 0001-690X
    DOI 10.1111/acps.13363
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  4. Article: Benefits following community treatment orders have an inverse relationship with rates of use: meta-analysis and meta-regression.

    Kisely, Steve / McMahon, Laura / Siskind, Dan

    BJPsych open

    2023  Volume 9, Issue 3, Page(s) e68

    Abstract: Background: Community treatment order (CTO) use in Australia and New Zealand ranges from less than 40 per 100 000 population in Western Australia and Canterbury to over 100 per 100 000 in Victoria, South Australia and Waitemata. Recent publications on ... ...

    Abstract Background: Community treatment order (CTO) use in Australia and New Zealand ranges from less than 40 per 100 000 population in Western Australia and Canterbury to over 100 per 100 000 in Victoria, South Australia and Waitemata. Recent publications on CTO use now permit a meta-regression to investigate whether differences in CTO use by jurisdiction affect either the possible predictors or outcomes of CTOs.
    Aims: To assess whether factors associated with CTO placement or subsequent outcomes vary by rates of use.
    Method: A systematic search of PubMed/Medline, Embase, CINAHL, the Cochrane Central Register of Controlled Trials and PsycINFO for any Australian or New Zealand study comparing CTO cases with controls receiving voluntary psychiatric treatment. This study was prospectively registered with PROSPERO (protocol registration number: CRD42022351500).
    Results: There were 35 articles from 16 studies identified in the search, plus unpublished data from a further study. Of these, 29 publications were included in meta-analyses. Two were from New Zealand. People who were male, single and not engaged in work, study or home duties were significantly more likely to be on CTOs. In addition, those from migrant backgrounds were 47% more likely to be on an order. On meta-regression, cases in jurisdictions with higher CTO rates had higher proportions of females or individuals with diagnoses other than non-affective psychoses. High-use jurisdictions were also less likely to show reductions in readmission rates or bed-days.
    Conclusions: There are marked differences in the possible predictors and outcomes of CTO placement between high- and low-use jurisdictions in Australia and New Zealand. These findings may have implications elsewhere and indicate that better-targeted CTO placement might improve outcomes.
    Language English
    Publishing date 2023-04-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2829557-2
    ISSN 2056-4724
    ISSN 2056-4724
    DOI 10.1192/bjo.2023.28
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  5. Article ; Online: Letter to the editor: Comments on "Prevalence and predictors of QTc prolongation in patients seen in a clozapine clinic in a real-world setting in Australia".

    Tanzer, Timothy / Winckel, Karl / Isoardi, Katherine / Smith, Lesley / Andric, Teodora / Siskind, Dan

    Schizophrenia research

    2024  Volume 264, Page(s) 370–371

    MeSH term(s) Humans ; Clozapine/adverse effects ; Prevalence ; Antipsychotic Agents/adverse effects ; Risk Factors ; Long QT Syndrome/chemically induced ; Long QT Syndrome/epidemiology ; Electrocardiography
    Chemical Substances Clozapine (J60AR2IKIC) ; Antipsychotic Agents
    Language English
    Publishing date 2024-01-16
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2024.01.003
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  6. Article: Correction.

    Siskind, Dan

    BJPsych open

    2016  Volume 2, Issue 2, Page(s) 187

    Abstract: This corrects the article DOI: 10.1192/bjpo.bp.115.001073.]. ...

    Abstract [This corrects the article DOI: 10.1192/bjpo.bp.115.001073.].
    Language English
    Publishing date 2016-04-13
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 2829557-2
    ISSN 2056-4724
    ISSN 2056-4724
    DOI 10.1192/bjpo.bp.116.003103
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  7. Article ; Online: Clozapine-balancing the body and the mind.

    Siskind, Dan / Myles, Nick / Kisely, Steve

    The lancet. Psychiatry

    2022  Volume 9, Issue 5, Page(s) 338–339

    MeSH term(s) Antipsychotic Agents/adverse effects ; Clozapine/adverse effects ; Humans ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents ; Clozapine (J60AR2IKIC)
    Language English
    Publishing date 2022-03-22
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(22)00078-5
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  8. Article ; Online: Admissions for psychosis following agency-notified child maltreatment at 40-year-follow-up: Results from the Childhood Adversity and Lifetime Morbidity (CALM) cohort.

    Kisely, Steve / Arnautovska, Urska / Siskind, Dan / Warren, Nicola / Najman, Jake Moses

    Schizophrenia research

    2024  Volume 267, Page(s) 247–253

    Abstract: There is substantial evidence of an association between self-reported child maltreatment (CM) and subsequent psychosis in retrospective data. Such findings may be affected by recall bias. Prospective studies of notifications to statutory agencies address ...

    Abstract There is substantial evidence of an association between self-reported child maltreatment (CM) and subsequent psychosis in retrospective data. Such findings may be affected by recall bias. Prospective studies of notifications to statutory agencies address recall bias but are less common and subject to attrition bias. These studies may therefore be underpowered to detect significant associations for some CM types such as sexual abuse. This study therefore linked administrative health data to a large birth cohort that included notifications to child protection agencies. We assessed psychiatric outcomes of CM as measured by inpatient admissions for non-affective psychoses (ICD10 codes F20-F29) to both public and private hospitals in Brisbane, Australia. Follow-up was up to 40 years old. There were 6087 cohort participants whose data could be linked to the administrative health data. Of these, 10.1 % had been the subject of a CM notification. Seventy-two participants (1.2 %) had been admitted for non-affective psychosis by 40-year follow-up. On adjusted analysis, all notified and substantiated types of CM were associated with admissions for non-affective psychosis. This included neglect, physical, sexual or emotional abuse, as well as notifications for multiple CM types. For instance, there was a 2.72-fold increase in admissions following any agency notification (95 % CI = 1.53-4.85). All maltreatment types therefore show a significant association with subsequent admissions for psychosis up to the age of 40. Screening for CM in individuals who present with psychosis is, therefore, indicated, as well as greater awareness that survivors of CM may be at higher risk of developing psychotic symptoms.
    Language English
    Publishing date 2024-04-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2024.03.040
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  9. Article ; Online: Response rates to sequential trials of antipsychotic medications according to algorithms or treatment guidelines in psychotic disorders. A systematic review and meta-analysis.

    O'Donoghue, Brian / Piacenza, Francesco / Plapp, Helena / Siskind, Dan / Lyne, John

    Schizophrenia research

    2024  

    Abstract: Background: There is a relative lack of research evaluating the outcomes when treatment guidelines or algorithms for psychotic disorders are followed. This systematic review and meta-analysis determined the response rates to antipsychotic medications at ...

    Abstract Background: There is a relative lack of research evaluating the outcomes when treatment guidelines or algorithms for psychotic disorders are followed. This systematic review and meta-analysis determined the response rates to antipsychotic medications at different stages of these algorithms and whether these response rates differ in first episode cohorts.
    Methods: Data sources: A systematic search strategy was conducted across four databases PubMed, EMBASE, PsycINFO (Ovid) and CINAHL. Studies that had sequential trials of different antipsychotic medications were included. A meta-analysis of proportions was performed using random effects models and sub-group analysis in first episode psychosis studies.
    Results: Of the 4078 unique articles screened, fourteen articles, from nine unique studies, were eligible and included 2522 participants. The proportion who experienced a response to any antipsychotic in the first stage of an algorithm was 0.53 (95 % C.I.:0.38,0.68) and this decreased to 0.26 (95 % C.I.:0.15,0.39) in the second stage. When clozapine was used in the third stage, the proportion that achieved a response was 0.43 (95 % C.I. 0.19, 0.69) compared to 0.26 (95 % C.I.:0.05,0.54) if a different antipsychotic was used. Four studies included 907 participants with a first episode of psychosis and the proportions that achieved a response were: 1st stage: 0.63 (95 % C.I.: 0.45, 0.79); 2nd stage: 0.34 (95 % C.I.:0.16,0.55); clozapine 3rd stage: 0.45 (95 % C.I.:0.0,0.97), different antipsychotic 3rd stage: 0.15 (95 % C.I.,0.01,0.37).
    Discussion: These findings support the recommendation to have a trial of clozapine after two other antipsychotic medications have been found to be ineffective.
    Language English
    Publishing date 2024-03-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2024.02.035
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  10. Article ; Online: Phenelzine discontinuation: A bitter pill to swallow.

    Smith, Lesley / Siskind, Dan

    The Australian and New Zealand journal of psychiatry

    2020  Volume 55, Issue 8, Page(s) 831–832

    MeSH term(s) Humans ; Phenelzine
    Chemical Substances Phenelzine (O408N561GF)
    Language English
    Publishing date 2020-10-10
    Publishing country England
    Document type Letter
    ZDB-ID 221140-3
    ISSN 1440-1614 ; 0004-8674
    ISSN (online) 1440-1614
    ISSN 0004-8674
    DOI 10.1177/0004867420965700
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